KEGG   ORTHOLOGY: K07199Help
Entry
K07199                      KO                                     

Name
PRKAB
Definition
5'-AMP-activated protein kinase, regulatory beta subunit
Pathway
ko04068  FoxO signaling pathway
ko04152  AMPK signaling pathway
ko04211  Longevity regulating pathway
ko04213  Longevity regulating pathway - multiple species
ko04371  Apelin signaling pathway
ko04530  Tight junction
ko04710  Circadian rhythm
ko04714  Thermogenesis
ko04910  Insulin signaling pathway
ko04920  Adipocytokine signaling pathway
ko04921  Oxytocin signaling pathway
ko04922  Glucagon signaling pathway
ko04931  Insulin resistance
ko04932  Non-alcoholic fatty liver disease (NAFLD)
ko05410  Hypertrophic cardiomyopathy (HCM)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04371 Apelin signaling pathway
    K07199  PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
   04068 FoxO signaling pathway
    K07199  PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
   04152 AMPK signaling pathway
    K07199  PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04530 Tight junction
    K07199  PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    K07199  PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
   04922 Glucagon signaling pathway
    K07199  PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
   04920 Adipocytokine signaling pathway
    K07199  PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
   04921 Oxytocin signaling pathway
    K07199  PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
  09149 Aging
   04211 Longevity regulating pathway
    K07199  PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
   04213 Longevity regulating pathway - multiple species
    K07199  PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
  09159 Environmental adaptation
   04710 Circadian rhythm
    K07199  PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
   04714 Thermogenesis
    K07199  PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
 09160 Human Diseases
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy (HCM)
    K07199  PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease (NAFLD)
    K07199  PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
   04931 Insulin resistance
    K07199  PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
BRITE hierarchy
Genes
HSA: 5564(PRKAB1) 5565(PRKAB2)
PTR: 452297(PRKAB1) 457245(PRKAB2)
PPS: 100972311(PRKAB2) 100975205(PRKAB1)
GGO: 101126241(PRKAB1) 101151966(PRKAB2)
PON: 100173201(PRKAB1)
NLE: 100597131(PRKAB2) 100600676(PRKAB1)
MCC: 695737(PRKAB1) 699806(PRKAB2)
MCF: 101925338(PRKAB2) 102133927(PRKAB1)
CSAB: 103239238(PRKAB1) 103247234(PRKAB2)
RRO: 104666241(PRKAB1) 104678672(PRKAB2)
RBB: 108517082(PRKAB2) 108534006(PRKAB1)
CJC: 100406673(PRKAB2) 100409760(PRKAB1)
SBQ: 101029046(PRKAB1) 101051388(PRKAB2)
MMU: 108097(Prkab2) 19079(Prkab1)
MCAL: 110290879(Prkab2) 110295068(Prkab1)
MPAH: 110312867(Prkab1) 110320445(Prkab2)
RNO: 64562(Prkab2) 83803(Prkab1)
MUN: 110545578(Prkab1) 110545905(Prkab2)
CGE: 100755226(Prkab1) 100772359(Prkab2)
NGI: 103726789(Prkab1) 103731998(Prkab2)
HGL: 101705863(Prkab1) 101720100(Prkab2)
CCAN: 109696161(Prkab1) 109696888(Prkab2)
OCU: 100340412(PRKAB2) 100348780(PRKAB1)
TUP: 102471560(PRKAB1) 102477154(PRKAB2)
CFA: 100856379(PRKAB2) 486295(PRKAB1)
VVP: 112907666(PRKAB2) 112932888(PRKAB1)
AML: 100463656(PRKAB1) 100475764(PRKAB2)
UMR: 103678332(PRKAB1) 103678391(PRKAB2)
UAH: 113247754(PRKAB2) 113267029(PRKAB1)
ORO: 101372153(PRKAB1) 101383756(PRKAB2)
FCA: 101092284(PRKAB2) 101094051(PRKAB1)
PTG: 102952112(PRKAB1) 102972403(PRKAB2)
PPAD: 109259142(PRKAB2) 109277549(PRKAB1)
AJU: 106971697(PRKAB1) 106985832(PRKAB2)
BTA: 512665(PRKAB2) 534107(PRKAB1)
BOM: 102275377(PRKAB2) 102278235(PRKAB1)
BIU: 109555847(PRKAB2) 109571380(PRKAB1)
BBUB: 102390878(PRKAB1) 102412137(PRKAB2)
CHX: 102169928(PRKAB2) 102181705(PRKAB1)
OAS: 101107899(PRKAB1) 101113114(PRKAB2)
SSC: 100156537(PRKAB1) 100157793(PRKAB2)
CFR: 102510343(PRKAB1) 102516135(PRKAB2)
CDK: 105089467(PRKAB2) 105104898(PRKAB1)
BACU: 103015065(PRKAB1) 103019135(PRKAB2)
LVE: 103085288(PRKAB1) 103089470(PRKAB2)
OOR: 101270605(PRKAB2) 101289338(PRKAB1)
DLE: 111179952(PRKAB2) 111186924(PRKAB1)
PCAD: 102993617(PRKAB2) 102995296(PRKAB1)
ECB: 100034094(PRKAB1) 100034095(PRKAB2)
EPZ: 103540717(PRKAB1) 103542394(PRKAB2)
EAI: 106844778(PRKAB1) 106847656(PRKAB2)
MYB: 102242848(PRKAB1) 102250933(PRKAB2)
MYD: 102766305(PRKAB2) 102768765(PRKAB1)
MNA: 107528511(PRKAB1) 107543870(PRKAB2)
HAI: 109386179(PRKAB1) 109389886(PRKAB2)
DRO: 112310730(PRKAB1) 112317360(PRKAB2)
PALE: 102886980(PRKAB1) 102887949(PRKAB2)
RAY: 107500976(PRKAB2) 107513175(PRKAB1)
MJV: 108403327(PRKAB2) 108408200(PRKAB1)
LAV: 100665273(PRKAB2) 100676546(PRKAB1)
MDO: 100013848(PRKAB2) 100014200(PRKAB1)
SHR: 100919221(PRKAB1) 105750525(PRKAB2)
PCW: 110219773(PRKAB2) 110222786(PRKAB1)
OAA: 100083731(PRKAB2) 100093063(PRKAB1)
GGA: 416986(PRKAB1) 427017(PRKAB2)
MGP: 100543948(PRKAB1) 100551469(PRKAB2)
CJO: 107317110(PRKAB2) 107321393(PRKAB1)
NMEL: 110402546(PRKAB2) 110406386(PRKAB1)
APLA: 101803934(PRKAB2) 101805480(PRKAB1)
ACYG: 106031361(PRKAB1) 106041622(PRKAB2)
TGU: 100218045(PRKAB2) 100220812(PRKAB1)
LSR: 110478962(PRKAB2) 110481337(PRKAB1)
SCAN: 103818046(PRKAB1) 103824682(PRKAB2)
GFR: 102039548(PRKAB2) 102045511(PRKAB1)
FAB: 101807095(PRKAB1) 101807509(PRKAB2)
PHI: 102108217(PRKAB1) 102110041(PRKAB2)
PMAJ: 107208034(PRKAB2) 107211650(PRKAB1)
CCAE: 111932675(PRKAB2) 111936584(PRKAB1)
CCW: 104688531(PRKAB1) 104695440(PRKAB2)
ETL: 114056606(PRKAB1) 114063939(PRKAB2)
FPG: 101918959(PRKAB1) 101922375(PRKAB2)
FCH: 102054722(PRKAB2) 102057661(PRKAB1)
CLV: 102096409(PRKAB2) 102096945(PRKAB1)
EGZ: 104129861(PRKAB1) 104132070(PRKAB2)
NNI: 104010405(PRKAB2) 104011465(PRKAB1)
ACUN: 113482653(PRKAB2) 113485960(PRKAB1)
PADL: 103914003(PRKAB2) 103922641(PRKAB1)
AAM: 106486336(PRKAB1) 106499653(PRKAB2)
ASN: 102382402(PRKAB1) 102383969(PRKAB2)
AMJ: 102560973(PRKAB2) 102568469(PRKAB1)
CMY: 102931879(PRKAB1) 102938628
CPIC: 101941080(PRKAB2) 101943824(PRKAB1)
ACS: 100553465(prkab1) 100554551(prkab2)
PVT: 110088958(PRKAB1) 110089841(PRKAB2)
PBI: 103053428 103056425(PRKAB1)
PMUR: 107288822(PRKAB1) 107301177(PRKAB2)
TSR: 106543036
PMUA: 114586440(PRKAB1) 114598478(PRKAB2)
GJA: 107119945(PRKAB2) 107122271(PRKAB1)
XLA: 108715739(prkab2.S) 108715919 380372(prkab2.L) 443998(prkab1.S)
XTR: 100127782(prkab2) 100380160(prkab1)
NPR: 108800403(PRKAB1)
DRE: 100170795(prkab2) 335232(prkab1b) 436905(prkab1a)
IPU: 100528577(aakb1) 108277360(prkab1) 108280523
LCM: 102345693(PRKAB2) 102350587(PRKAB1)
CMK: 103179976 103189858(prkab1)
CIN: 100184659
SPU: 592944
APLC: 110975207
SKO: 100371289
DME: Dmel_CG8057(alc)
DER: 6541042
DSI: Dsimw501_GD10101(Dsim_GD10101)
DSR: 110188970
DPE: 6592854
DMN: 108158668
DWI: 6652421
DAZ: 108616272
DNV: 108653486
DHE: 111603436
MDE: 101897466
LCQ: 111678225
AAG: 5573949
AALB: 109421303
AME: 409662
BIM: 100740818
BTER: 100649644
CCAL: 108624367
OBB: 114876081
SOC: 105200212
MPHA: 105829273
AEC: 105153371
ACEP: 105619482
PBAR: 105434289
VEM: 105564260
HST: 105184528
DQU: 106743034
CFO: 105255812
LHU: 105671840
PGC: 109858397
OBO: 105287660
NVI: 100120670(alc)
CSOL: 105364774
MDL: 103571613
TCA: 659775
ATD: 109609432
NVL: 108567643
BMOR: 100126177
BMAN: 114248640
PMAC: 106714859
PRAP: 110993995
HAW: 110376128
TNL: 113497553
API: 100166968
DNX: 107170076
AGS: 114119146
RMD: 113551221
BTAB: 109034357
CLEC: 106666494
ZNE: 110834362
FCD: 110859296
PVM: 113828134
TUT: 107364490
DPTE: 113793926
PTEP: 107437588
CEL: CELE_F55F3.1(aakb-1) CELE_Y47D3A.15(aakb-2)
CBR: CBG07378(Cbr-aakb-1) CBG13217(Cbr-aakb-2)
BMY: Bm1_18185
TSP: Tsp_05912
PCAN: 112571309
CRG: 105344372
MYI: 110452686
OBI: 106872364
EPA: 110235926
AMIL: 114975189
PDAM: 113664517
SPIS: 111325834
DGT: 114537076
HMG: 100212092
AQU: 100634103
ATH: AT4G16360 AT5G21170(AKINBETA1)
LJA: Lj0g3v0233389.1(Lj0g3v0233389.1) Lj6g3v1721620.1(Lj6g3v1721620.1)
SLY: 101055581 101055582 543678(Sip1) 543876(GAL83)
DOSA: Os03t0319100-01(Os03g0319100) Os05t0491200-01(Os05g0491200) Os07t0687300-01(Os07g0687300)
ATS: 109750595(LOC109750595) 109768115(LOC109768115) 109770856(LOC109770856)
APRO: F751_6239
SPO: SPCC1919.03c(amk2)
SMIN: v1.2.030067.t1(symbB.v1.2.030067.t1)
SPAR: SPRG_15880
 » show all
TaxonomyKoalaUniProt
Reference
PMID:8663446
  Authors
Dyck JR, Gao G, Widmer J, Stapleton D, Fernandez CS, Kemp BE, Witters LA
  Title
Regulation of 5'-AMP-activated protein kinase activity by the noncatalytic beta and gamma subunits.
  Journal
J Biol Chem 271:17798-803 (1996)
DOI:10.1074/jbc.271.30.17798
Reference
PMID:9224708
  Authors
Stapleton D, Woollatt E, Mitchelhill KI, Nicholl JK, Fernandez CS, Michell BJ, Witters LA, Power DA, Sutherland GR, Kemp BE
  Title
AMP-activated protein kinase isoenzyme family: subunit structure and chromosomal location.
  Journal
FEBS Lett 409:452-6 (1997)
DOI:10.1016/S0014-5793(97)00569-3
  Sequence
[hsa:5564]
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