KEGG   ORTHOLOGY: K07436Help
Entry
K07436                      KO                                     

Name
CYP24A1
Definition
vitamin D3 24-hydroxylase [EC:1.14.15.16]
Pathway
ko00100  Steroid biosynthesis
ko01100  Metabolic pathways
ko04928  Parathyroid hormone synthesis, secretion and action
ko05206  MicroRNAs in cancer
Disease
H01371  Hypercalcemia infantile
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09103 Lipid metabolism
   00100 Steroid biosynthesis
    K07436  CYP24A1; vitamin D3 24-hydroxylase
 09150 Organismal Systems
  09152 Endocrine system
   04928 Parathyroid hormone synthesis, secretion and action
    K07436  CYP24A1; vitamin D3 24-hydroxylase
 09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    K07436  CYP24A1; vitamin D3 24-hydroxylase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450
    K07436  CYP24A1; vitamin D3 24-hydroxylase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.15  With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.15.16  vitamin D3 24-hydroxylase
     K07436  CYP24A1; vitamin D3 24-hydroxylase
Cytochrome P450 [BR:ko00199]
 Cytochrome P450, animal type
  CYP24 family
   K07436  CYP24A1; vitamin D3 24-hydroxylase
BRITE hierarchy
Other DBs
RN: R09515 R09516
GO: 0008403 0030342
Genes
HSA: 1591(CYP24A1)
PTR: 746729(CYP24A1)
PPS: 100971976
GGO: 101142284
PON: 100457433
NLE: 100603459
MCC: 698937
MCF: 102117231
CSAB: 103243965(CYP24A1)
RRO: 104662355
RBB: 108521781
CJC: 100393283
SBQ: 101054511
MMU: 13081(Cyp24a1)
MCAL: 110289544
MPAH: 110318266
RNO: 25279(Cyp24a1)
MUN: 110545262
CGE: 100751280
NGI: 103735781
HGL: 101716773
CCAN: 109694681
OCU: 100347441
TUP: 102471055
CFA: 485935(CYP24A1)
VVP: 112931920
AML: 100479790
UMR: 103669826
UAH: 113258741
ORO: 101384402
ELK: 111141789
FCA: 101096141
PTG: 102967619
PPAD: 109272242
AJU: 106970319
BTA: 540080(CYP24A1)
BOM: 102272075
BIU: 109567562
BBUB: 102396198
CHX: 102178921
OAS: 100170323(CYP24)
SSC: 397145(CYP24A1)
CFR: 102516204
CDK: 105098859
BACU: 103015403
LVE: 103082411
OOR: 101271151
DLE: 111186695
PCAD: 102977275
ECB: 100053452(CYP24A1)
EPZ: 103554239
EAI: 106825434
MYD: 102772049
MNA: 107536509
DRO: 112304205
PALE: 102878689
RAY: 107498143
MJV: 108390269
LAV: 100663262
TMU: 101353460
MDO: 100028177
SHR: 100916072
PCW: 110206681
OAA: 100078505
GGA: 395827(CYP24A1)
MGP: 100541378
CJO: 107323241
NMEL: 110408247
APLA: 101797037
ACYG: 106041795
TGU: 100226727
LSR: 110472394
SCAN: 103818886
GFR: 102044237
FAB: 101813067
PHI: 102111029
PMAJ: 107213207
CCAE: 111938004
CCW: 104687601
ETL: 114056255
FPG: 101919538
FCH: 102046853
CLV: 102098516
EGZ: 104132191
NNI: 104013059
ACUN: 113487633
PADL: 103919278
AAM: 106491745
ASN: 102382614
AMJ: 102574966(CYP24A1)
PSS: 102458142
CPIC: 101938071
PVT: 110071817
PBI: 103065707
PMUR: 107287085
TSR: 106547483
PMUA: 114599654
GJA: 107119104
XTR: 100496967 100497429(cyp24a1)
DRE: 100004700(cyp24a1)
CCAR: 109057669
IPU: 108271496(CYP24A1)
PHYP: 113532087
AMEX: 103030576
EEE: 113571660
TRU: 101077963
LCO: 104935382
NCC: 104966082
MZE: 101475325
ONL: 100690876
OLA: 101165632
XMA: 102225814
XCO: 114135962
PRET: 103464673
CVG: 107097105
NFU: 107385407
KMR: 108231477
ALIM: 106533681
AOCE: 111579624
CSEM: 103386736
POV: 109635373
LCF: 108873562
SDU: 111233601
SLAL: 111660685
HCQ: 109507475
BPEC: 110171174
MALB: 109951265
SASA: 106565076(CP24A) 106583685
ELS: 105016677
SFM: 108936451
PKI: 111835893
LCM: 102364004
CMK: 103191047
RTP: 109910917
DGT: 114535530
 » show all
TaxonomyKoalaUniProt
Reference
PMID:8506296
  Authors
Chen KS, Prahl JM, DeLuca HF
  Title
Isolation and expression of human 1,25-dihydroxyvitamin D3 24-hydroxylase cDNA.
  Journal
Proc Natl Acad Sci U S A 90:4543-7 (1993)
DOI:10.1073/pnas.90.10.4543
  Sequence
[hsa:1591]
Reference
  Authors
Prosser DE, Jones G
  Title
Enzymes involved in the activation and inactivation of vitamin D.
  Journal
Trends Biochem Sci 29:664-73 (2004)
DOI:10.1016/j.tibs.2004.10.005
LinkDB All DBs

DBGET integrated database retrieval system