KEGG ORTHOLOGY: K08030

ORTHOLOGY: K08030

Entry

K08030 KO

Name

NKX6-1

Definition

homeobox protein Nkx-6.1

Pathway

ko04950

Maturity onset diabetes of the young

Brite

KEGG Orthology (KO) [BR:ko00001]
09160 Human Diseases
  09167 Endocrine and metabolic disease
   04950 Maturity onset diabetes of the young
    K08030  NKX6-1; homeobox protein Nkx-6.1
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K08030  NKX6-1; homeobox protein Nkx-6.1
Transcription factors [BR:ko03000]
Eukaryotic type
  Helix-turn-helix
   Homeo domain ANTP: NKL
    K08030  NKX6-1; homeobox protein Nkx-6.1

Genes

HSA:	4825(NKX6-1)

PTR:	471184(NKX6-1)

PPS:	100980863(NKX6-1)

GGO:	101125547(NKX6-1)

PON:	100452932(NKX6-1)

NLE:	100599362(NKX6-1)

MCC:	706844(NKX6-1)

MCF:	102117152(NKX6-1)

CSAB:

103235908(NKX6-1)

RRO:	104672946(NKX6-1)

RBB:	108515056(NKX6-1)

CJC:	100411255(NKX6-1)

SBQ:	101046277(NKX6-1)

MMU:	18096(Nkx6-1)

MCAL:

110295088(Nkx6-1)

MPAH:

110330719(Nkx6-1)

RNO:	65193(Nkx6-1)

MUN:	110559967(Nkx6-1)

CGE:

100772326

NGI:	103748978(Nkx6-1)

HGL:	101725924(Nkx6-1)

CCAN:

109702391(Nkx6-1)

OCU:	100352599(NKX6-1)

TUP:	102476961(NKX6-1)

CFA:	487838(NKX6-1)

VVP:	112919682(NKX6-1)

AML:	100484069(NKX6-1)

UAH:	113263039(NKX6-1)

ORO:	101369764(NKX6-1)

ELK:

111157852

FCA:	101083167(NKX6-1)

PPAD:

109276434(NKX6-1)

AJU:	106981371(NKX6-1)

BTA:	616211(NKX6-1)

BOM:	102286643(NKX6-1)

BIU:	109560184(NKX6-1)

BBUB:

102407950(NKX6-1)

CHX:	108636284(NKX6-1)

OAS:	554330(NKX6-1)

SSC:	397289(NKX6-1)

CFR:	102512643(NKX6-1)

CDK:	105092209(NKX6-1)

BACU:

103020442(NKX6-1)

LVE:	103078159(NKX6-1)

OOR:	101281617(NKX6-1)

DLE:	111187674(NKX6-1)

PCAD:

102991273(NKX6-1)

ECB:	100062057(NKX6-1)

EPZ:	103563162(NKX6-1)

EAI:	106839424(NKX6-1)

HAI:	109387930(NKX6-1)

DRO:	112317724(NKX6-1)

PALE:

102887057(NKX6-1)

RAY:	107516442(NKX6-1)

MJV:

108391661

LAV:	100676719(NKX6-1)

TMU:

101346190

MDO:	100014461(NKX6-1)

SHR:	100927029(NKX6-1)

PCW:	110209853(NKX6-1)

OAA:	114815627(NKX6-1)

GGA:	395752(NKX6-1)

CJO:	107313332(NKX6-1)

NMEL:

110398565(NKX6-1)

APLA:

113843492

TGU:	100221914(NKX6-1)

LSR:	110468490(NKX6-1)

SCAN:

103826293(NKX6-1)

GFR:	102041432(NKX6-1)

PHI:	102103740(NKX6-1)

CCW:	120409919(NKX6-1)

ETL:	114057749(NKX6-1)

FPG:	101911623(NKX6-1)

CLV:

102097417

ASN:

102368808

AMJ:	102560653(NKX6-1)

CMY:	102944456(NKX6-1)

CPIC:

101940636(NKX6-1)

ACS:	100566166(nkx6-1)

PMUR:

107303188(NKX6-1)

TSR:	106548915(NKX6-1)

PMUA:

114604238(NKX6-1)

GJA:	107114183(NKX6-1)

XLA:	100101340(nkx6-1.L) 108704117

XTR:	549337(nkx6-1)

NPR:	108796140(NKX6-1)

DRE:	436748(nkx6.1)

SRX:	107706438 107722812

SANH:

107700773 107703597

SGH:	107589232(nkx6-1) 107591753

CCAR:

109068056 109080394 109091869

IPU:	108279193(nkx6-1)

PHYP:

113543212(nkx6-1)

AMEX:

103045404(nkx6-1)

EEE:	113570759(nkx6-1)

TRU:	101072825(nkx6-1)

TNG:	GSTEN00017153G001

LCO:	104933970(nkx6-1)

NCC:	104949089(nkx6-1)

MZE:	101473270(nkx6-1)

ONL:	100709199(nkx6-1)

OLA:	101156548(nkx6-1)

XMA:	102217630(nkx6-1)

XCO:	114149121(nkx6-1)

PRET:

103473493(nkx6-1)

CVG:	107096395(nkx6-1)

NFU:	107395174(nkx6-1)

KMR:	108242530(nkx6.1)

ALIM:

106513802(nkx6-1)

AOCE:

111587030(nkx6-1)

CSEM:

103390390(nkx6-1)

POV:	109640860(nkx6-1)

LCF:	108875548(nkx6-1)

SDU:	111238034(nkx6-1)

SLAL:

111649015

HCQ:	109517533(nkx6-1)

BPEC:

110161917(nkx6-1)

SASA:

106563667(nkx6-1) 106568160

OTW:	112219512(nkx6-1) 112257520

SALP:

111961406 111982158

ELS:	105014718(nkx6-1)

SFM:	108934180(nkx6-1)

PKI:	111842189(nkx6-1)

LCM:	102354358(NKX6-1)

RTP:

CIN:

SPU:

DER:

DSI:	Dsimw501_GD12614(Dsim_GD12614)

DYA:	Dyak_GE20015

DSR:

110182780

DPO:	Dpse_GA12313

DPE:

6601973

DMN:

108153581

DWI:

6651966

DGR:	Dgri_GH16803

DMO:	Dmoj_GI13817

DAZ:

DNV:

DHE:

MDE:

LCQ:

AGA:	AgaP_AGAP002431

AAG:

AME:

BIM:

BTER:

CCAL:

OBB:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:

DQU:

CFO:

LHU:

PGC:

OBO:

PCF:

NVI:

CSOL:

MDL:

TCA:

DPA:

ATD:

NVL:

DNX:

RMD:

FCD:

PVM:

TUT:

DPTE:

CBR:	CBG20882(Cbr-cog-1)

TSP:	Tsp_06645 Tsp_13445

SMM:	Smp_126870

OVI:	T265_00770

EGL:

PDAM:

SPIS:

Reference

PMID:11076772

Authors

Sander M, Sussel L, Conners J, Scheel D, Kalamaras J, Dela Cruz F, Schwitzgebel V, Hayes-Jordan A, German M

Title

Homeobox gene Nkx6.1 lies downstream of Nkx2.2 in the major pathway of beta-cell formation in the pancreas.

Journal

Development 127:5533-40 (2000)

Sequence

[mmu:18096]

LinkDB

DBGET integrated database retrieval system