KEGG   ORTHOLOGY: K08042Help
Entry
K08042                      KO                                     

Name
ADCY2
Definition
adenylate cyclase 2 [EC:4.6.1.1]
Pathway
ko00230  Purine metabolism
ko01100  Metabolic pathways
ko01522  Endocrine resistance
ko04015  Rap1 signaling pathway
ko04020  Calcium signaling pathway
ko04022  cGMP-PKG signaling pathway
ko04024  cAMP signaling pathway
ko04062  Chemokine signaling pathway
ko04072  Phospholipase D signaling pathway
ko04114  Oocyte meiosis
ko04211  Longevity regulating pathway
ko04213  Longevity regulating pathway - multiple species
ko04261  Adrenergic signaling in cardiomyocytes
ko04270  Vascular smooth muscle contraction
ko04371  Apelin signaling pathway
ko04540  Gap junction
ko04611  Platelet activation
ko04713  Circadian entrainment
ko04714  Thermogenesis
ko04723  Retrograde endocannabinoid signaling
ko04724  Glutamatergic synapse
ko04725  Cholinergic synapse
ko04727  GABAergic synapse
ko04750  Inflammatory mediator regulation of TRP channels
ko04911  Insulin secretion
ko04912  GnRH signaling pathway
ko04913  Ovarian steroidogenesis
ko04914  Progesterone-mediated oocyte maturation
ko04915  Estrogen signaling pathway
ko04916  Melanogenesis
ko04918  Thyroid hormone synthesis
ko04921  Oxytocin signaling pathway
ko04922  Glucagon signaling pathway
ko04923  Regulation of lipolysis in adipocytes
ko04925  Aldosterone synthesis and secretion
ko04926  Relaxin signaling pathway
ko04927  Cortisol synthesis and secretion
ko04928  Parathyroid hormone synthesis, secretion and action
ko04934  Cushing syndrome
ko04935  Growth hormone synthesis, secretion and action
ko04970  Salivary secretion
ko04971  Gastric acid secretion
ko04972  Pancreatic secretion
ko04976  Bile secretion
ko05032  Morphine addiction
ko05163  Human cytomegalovirus infection
ko05166  Human T-cell leukemia virus 1 infection
ko05200  Pathways in cancer
ko05414  Dilated cardiomyopathy (DCM)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    K08042  ADCY2; adenylate cyclase 2
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    K08042  ADCY2; adenylate cyclase 2
   04371 Apelin signaling pathway
    K08042  ADCY2; adenylate cyclase 2
   04020 Calcium signaling pathway
    K08042  ADCY2; adenylate cyclase 2
   04072 Phospholipase D signaling pathway
    K08042  ADCY2; adenylate cyclase 2
   04024 cAMP signaling pathway
    K08042  ADCY2; adenylate cyclase 2
   04022 cGMP-PKG signaling pathway
    K08042  ADCY2; adenylate cyclase 2
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    K08042  ADCY2; adenylate cyclase 2
  09144 Cellular community - eukaryotes
   04540 Gap junction
    K08042  ADCY2; adenylate cyclase 2
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    K08042  ADCY2; adenylate cyclase 2
   04062 Chemokine signaling pathway
    K08042  ADCY2; adenylate cyclase 2
  09152 Endocrine system
   04911 Insulin secretion
    K08042  ADCY2; adenylate cyclase 2
   04922 Glucagon signaling pathway
    K08042  ADCY2; adenylate cyclase 2
   04923 Regulation of lipolysis in adipocytes
    K08042  ADCY2; adenylate cyclase 2
   04912 GnRH signaling pathway
    K08042  ADCY2; adenylate cyclase 2
   04913 Ovarian steroidogenesis
    K08042  ADCY2; adenylate cyclase 2
   04915 Estrogen signaling pathway
    K08042  ADCY2; adenylate cyclase 2
   04914 Progesterone-mediated oocyte maturation
    K08042  ADCY2; adenylate cyclase 2
   04921 Oxytocin signaling pathway
    K08042  ADCY2; adenylate cyclase 2
   04926 Relaxin signaling pathway
    K08042  ADCY2; adenylate cyclase 2
   04935 Growth hormone synthesis, secretion and action
    K08042  ADCY2; adenylate cyclase 2
   04918 Thyroid hormone synthesis
    K08042  ADCY2; adenylate cyclase 2
   04928 Parathyroid hormone synthesis, secretion and action
    K08042  ADCY2; adenylate cyclase 2
   04916 Melanogenesis
    K08042  ADCY2; adenylate cyclase 2
   04925 Aldosterone synthesis and secretion
    K08042  ADCY2; adenylate cyclase 2
   04927 Cortisol synthesis and secretion
    K08042  ADCY2; adenylate cyclase 2
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    K08042  ADCY2; adenylate cyclase 2
   04270 Vascular smooth muscle contraction
    K08042  ADCY2; adenylate cyclase 2
  09154 Digestive system
   04970 Salivary secretion
    K08042  ADCY2; adenylate cyclase 2
   04971 Gastric acid secretion
    K08042  ADCY2; adenylate cyclase 2
   04972 Pancreatic secretion
    K08042  ADCY2; adenylate cyclase 2
   04976 Bile secretion
    K08042  ADCY2; adenylate cyclase 2
  09156 Nervous system
   04724 Glutamatergic synapse
    K08042  ADCY2; adenylate cyclase 2
   04727 GABAergic synapse
    K08042  ADCY2; adenylate cyclase 2
   04725 Cholinergic synapse
    K08042  ADCY2; adenylate cyclase 2
   04723 Retrograde endocannabinoid signaling
    K08042  ADCY2; adenylate cyclase 2
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    K08042  ADCY2; adenylate cyclase 2
  09149 Aging
   04211 Longevity regulating pathway
    K08042  ADCY2; adenylate cyclase 2
   04213 Longevity regulating pathway - multiple species
    K08042  ADCY2; adenylate cyclase 2
  09159 Environmental adaptation
   04713 Circadian entrainment
    K08042  ADCY2; adenylate cyclase 2
   04714 Thermogenesis
    K08042  ADCY2; adenylate cyclase 2
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K08042  ADCY2; adenylate cyclase 2
  09165 Substance dependence
   05032 Morphine addiction
    K08042  ADCY2; adenylate cyclase 2
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy (DCM)
    K08042  ADCY2; adenylate cyclase 2
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    K08042  ADCY2; adenylate cyclase 2
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K08042  ADCY2; adenylate cyclase 2
   05163 Human cytomegalovirus infection
    K08042  ADCY2; adenylate cyclase 2
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    K08042  ADCY2; adenylate cyclase 2
Enzymes [BR:ko01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     K08042  ADCY2; adenylate cyclase 2
BRITE hierarchy
Other DBs
RN: R00089 R00434
GO: 0004016
Genes
HSA: 108(ADCY2)
PTR: 100608010(ADCY2)
PPS: 100992014(ADCY2)
GGO: 101141389(ADCY2)
PON: 100445431(ADCY2)
NLE: 100600367(ADCY2)
MCC: 695328(ADCY2)
MCF: 102130114(ADCY2)
CSAB: 103214981(ADCY2)
RRO: 104674083(ADCY2)
RBB: 108536960(ADCY2)
CJC: 100385658(ADCY2)
SBQ: 101043334(ADCY2)
MMU: 210044(Adcy2)
MCAL: 110307661(Adcy2)
MPAH: 110328764(Adcy2)
RNO: 81636(Adcy2)
MUN: 110550962
CGE: 100773811(Adcy2)
NGI: 103735350(Adcy2)
HGL: 101718304(Adcy2)
OCU: 100009201(ADCY2)
TUP: 102492353(ADCY2)
CFA: 478624(ADCY2)
VVP: 112934273(ADCY2)
AML: 100473195(ADCY2)
UMR: 103679250(ADCY2)
UAH: 113260807(ADCY2)
ORO: 101365382(ADCY2)
ELK: 111153427
FCA: 101094327(ADCY2)
PTG: 102949732(ADCY2)
PPAD: 109267830(ADCY2)
AJU: 106971248(ADCY2)
BTA: 510708(ADCY2)
BOM: 102274117(ADCY2)
BIU: 109574822(ADCY2)
BBUB: 102412622(ADCY2)
CHX: 102171922(ADCY2)
OAS: 101102089(ADCY2)
SSC: 100517503(ADCY2)
CFR: 102510993(ADCY2)
CDK: 105094039(ADCY2)
BACU: 103020085(ADCY2)
LVE: 103084817(ADCY2)
OOR: 101286207(ADCY2)
DLE: 111178556(ADCY2)
PCAD: 102991224(ADCY2)
ECB: 100071337(ADCY2)
EPZ: 103562505
EAI: 106823001(ADCY2)
MYB: 102260356(ADCY2)
MYD: 102774384(ADCY2)
MNA: 107540528(ADCY2)
HAI: 109375976(ADCY2)
DRO: 112321008(ADCY2)
PALE: 102893265(ADCY2)
RAY: 107502700(ADCY2)
LAV: 100673570(ADCY2)
TMU: 101360334
MDO: 100013164(ADCY2)
SHR: 100922434(ADCY2)
PCW: 110220436(ADCY2)
OAA: 100089708(ADCY2)
GGA: 420935(ADCY2)
MGP: 100540738(ADCY2)
CJO: 107309543(ADCY2)
NMEL: 110394300(ADCY2)
APLA: 101803512(ADCY2)
ACYG: 106036531(ADCY2)
TGU: 100223820(ADCY2)
LSR: 110479527(ADCY2)
SCAN: 103815408(ADCY2)
GFR: 102038853(ADCY2)
FAB: 101808400(ADCY2)
PHI: 102113898(ADCY2)
PMAJ: 107199935(ADCY2)
CCAE: 111925673(ADCY2)
CCW: 104685925(ADCY2)
ETL: 114055132(ADCY2)
FPG: 101911647(ADCY2)
FCH: 102049688(ADCY2)
CLV: 102097532(ADCY2)
EGZ: 104126191(ADCY2)
NNI: 104018888(ADCY2)
ACUN: 113476067(ADCY2)
PADL: 103915154(ADCY2)
AAM: 106492356(ADCY2)
ASN: 102383838(ADCY2)
AMJ: 102562034(ADCY2)
PSS: 102444057(ADCY2)
CMY: 102930552(ADCY2)
CPIC: 101952054(ADCY2)
ACS: 100555265(adcy2) 103279577
PVT: 110089596
PBI: 103050340(ADCY2)
PMUR: 107297625(ADCY2)
TSR: 106545186 106550009(ADCY2)
PMUA: 114601220(ADCY2)
GJA: 107108835(ADCY2)
DRE: 557902(adcy2b) 563724(adcy2a)
IPU: 108272199(Adcy2) 108272792(ADCY2)
XCO: 114141804 114156097(adcy2)
CVG: 107084393 107091823(adcy2)
KMR: 108232311 108238708(adcy2)
OTW: 112229303(adcy2) 112265839
SALP: 111954801(adcy2) 111955524
ELS: 105012408(adcy2)
CMK: 103183192(adcy2)
RTP: 109920424(adcy2)
SPU: 575180
APLC: 110980095
SKO: 102803250
DME: Dmel_CG7978(Ac76E)
DER: 6545709
DSI: Dsimw501_GD14841(Dsim_GD14841)
DSR: 110189922
DMN: 108152507
DWI: 6638793
DAZ: 108614292
DNV: 108651863
DHE: 111604449
MDE: 101893904
AAG: 5571159
AALB: 109418769
AME: 552216
BIM: 100745521
BTER: 100647623
CCAL: 108631101
OBB: 114880740
SOC: 105197184
MPHA: 105835065
AEC: 105143483
ACEP: 105617405
PBAR: 105425936
VEM: 105559069
HST: 105184375
DQU: 106746346
CFO: 105250746
LHU: 105670932
PGC: 109855918
OBO: 105285379
PCF: 106792130
NVI: 100118148
CSOL: 105367877
MDL: 103577402
TCA: 660403
NVL: 108567526
BMOR: 101737606
BMAN: 114243277
PMAC: 106718962
PRAP: 110995397
HAW: 110373694
TNL: 113497935
API: 100164066
DNX: 107167195
AGS: 114123846
RMD: 113553384
BTAB: 109030143
CLEC: 106667432
ZNE: 110829129
FCD: 110849688
PTEP: 107452662
PCAN: 112577004
CRG: 105336030
MYI: 110458458
 » show all
TaxonomyKoalaUniProt
Reference
PMID:1427768
  Authors
Stengel D, Parma J, Gannage MH, Roeckel N, Mattei MG, Barouki R, Hanoune J
  Title
Different chromosomal localization of two adenylyl cyclase genes expressed in human brain.
  Journal
Hum Genet 90:126-30 (1992)
DOI:10.1007/BF00210755
  Sequence
[hsa:108]
Reference
  Authors
Hardin M, Zielinski J, Wan ES, Hersh CP, Castaldi PJ, Schwinder E, Hawrylkiewicz I, Sliwinski P, Cho MH, Silverman EK
  Title
CHRNA3/5, IREB2, and ADCY2 are associated with severe chronic obstructive pulmonary disease in Poland.
  Journal
Am J Respir Cell Mol Biol 47:203-8 (2012)
DOI:10.1165/rcmb.2012-0011OC
LinkDB All DBs

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