KEGG   ORTHOLOGY: K08524Help
Entry
K08524                      KO                                     

Name
RXRA, NR2B1
Definition
retinoid X receptor alpha
Pathway
ko03320  PPAR signaling pathway
ko04151  PI3K-Akt signaling pathway
ko04659  Th17 cell differentiation
ko04919  Thyroid hormone signaling pathway
ko04920  Adipocytokine signaling pathway
ko04928  Parathyroid hormone synthesis, secretion and action
ko04932  Non-alcoholic fatty liver disease (NAFLD)
ko04976  Bile secretion
ko05160  Hepatitis C
ko05200  Pathways in cancer
ko05202  Transcriptional misregulation in cancer
ko05216  Thyroid cancer
ko05222  Small cell lung cancer
ko05223  Non-small cell lung cancer
ko05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    K08524  RXRA, NR2B1; retinoid X receptor alpha
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    K08524  RXRA, NR2B1; retinoid X receptor alpha
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    K08524  RXRA, NR2B1; retinoid X receptor alpha
   03320 PPAR signaling pathway
    K08524  RXRA, NR2B1; retinoid X receptor alpha
   04919 Thyroid hormone signaling pathway
    K08524  RXRA, NR2B1; retinoid X receptor alpha
   04928 Parathyroid hormone synthesis, secretion and action
    K08524  RXRA, NR2B1; retinoid X receptor alpha
  09154 Digestive system
   04976 Bile secretion
    K08524  RXRA, NR2B1; retinoid X receptor alpha
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K08524  RXRA, NR2B1; retinoid X receptor alpha
   05202 Transcriptional misregulation in cancer
    K08524  RXRA, NR2B1; retinoid X receptor alpha
  09162 Cancer: specific types
   05226 Gastric cancer
    K08524  RXRA, NR2B1; retinoid X receptor alpha
   05216 Thyroid cancer
    K08524  RXRA, NR2B1; retinoid X receptor alpha
   05222 Small cell lung cancer
    K08524  RXRA, NR2B1; retinoid X receptor alpha
   05223 Non-small cell lung cancer
    K08524  RXRA, NR2B1; retinoid X receptor alpha
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease (NAFLD)
    K08524  RXRA, NR2B1; retinoid X receptor alpha
  09172 Infectious disease: viral
   05160 Hepatitis C
    K08524  RXRA, NR2B1; retinoid X receptor alpha
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K08524  RXRA, NR2B1; retinoid X receptor alpha
  09183 Protein families: signaling and cellular processes
   03310 Nuclear receptors
    K08524  RXRA, NR2B1; retinoid X receptor alpha
Transcription factors [BR:ko03000]
 Eukaryotic type
  Zinc finger
   Cys4 hepatocyte nuclear factor 4-like
    K08524  RXRA, NR2B1; retinoid X receptor alpha
Nuclear receptors [BR:ko03310]
 2. Hepatocyte nuclear factor 4 like
  2B. Retinoid X receptor (RXR)
   K08524  RXRA, NR2B1; retinoid X receptor alpha
BRITE hierarchy
Other DBs
GO: 0004886
Genes
HSA: 6256(RXRA)
PTR: 464834(RXRA)
PPS: 100989625(RXRA)
GGO: 101128749(RXRA)
NLE: 100585339(RXRA)
MCC: 722068(RXRA)
MCF: 102133330(RXRA)
CSAB: 103239669(RXRA)
RRO: 104669710(RXRA)
RBB: 108513168(RXRA)
CJC: 100407498(RXRA)
SBQ: 101044148(RXRA)
MMU: 20181(Rxra)
MCAL: 110308122(Rxra)
MPAH: 110317492(Rxra)
RNO: 25271(Rxra)
MUN: 110549176(Rxra)
CGE: 100768377(Rxra)
NGI: 103742823(Rxra)
HGL: 101723948(Rxra)
CCAN: 109695052(Rxra)
TUP: 102470277(RXRA)
CFA: 491278(RXRA)
VVP: 112906873(RXRA)
AML: 100479839(RXRA)
UMR: 103679944(RXRA)
UAH: 113266584(RXRA)
ORO: 101365135(RXRA)
FCA: 101085757(RXRA)
AJU: 106988254(RXRA)
BTA: 507554(RXRA)
BOM: 102265047(RXRA)
BIU: 109566619(RXRA)
BBUB: 102404333(RXRA)
PHD: 102332497
CHX: 106502091(RXRA) 108634606
OAS: 114113852(RXRA)
SSC: 397306(RXRA)
CFR: 102518674
CDK: 105106306(RXRA)
BACU: 103005517(RXRA)
LVE: 103083851(RXRA)
OOR: 101270600(RXRA)
DLE: 111177070(RXRA)
PCAD: 102992401(RXRA)
ECB: 100069096(RXRA)
EPZ: 103542697(RXRA)
EAI: 106845341(RXRA)
MYB: 102262918(RXRA)
MYD: 102762226(RXRA)
MNA: 107524613(RXRA)
HAI: 109381229(RXRA)
RSS: 109438438(RXRA)
DRO: 112302657 112306469(RXRA)
PALE: 102881572(RXRA)
RAY: 107502027(RXRA)
LAV: 100674208
TMU: 101353449
MDO: 100019466(RXRA)
SHR: 100926708(RXRA)
PCW: 110205364(RXRA)
OAA: 100074625
GGA: 417143(RXRA)
MGP: 100545391(RXRA)
CJO: 107321878(RXRA)
NMEL: 110406787(RXRA)
APLA: 101794030(RXRA)
ACYG: 106044107(RXRA)
TGU: 100231066(RXRA)
LSR: 110477629(RXRA)
SCAN: 103818959(RXRA)
GFR: 102037605(RXRA)
FAB: 101807658(RXRA)
PHI: 102099900(RXRA)
PMAJ: 107212084(RXRA)
CCAE: 111937054(RXRA)
CCW: 104688345(RXRA)
ETL: 114059088(RXRA)
FPG: 101923856(RXRA)
FCH: 102047863(RXRA)
CLV: 102098621(RXRA)
EGZ: 104129339(RXRA)
NNI: 104023200(RXRA)
ACUN: 113486536(RXRA)
PADL: 103915261(RXRA)
AAM: 106495473(RXRA)
ASN: 102384957(RXRA)
AMJ: 102567277(RXRA)
PSS: 102443949(RXRA)
CMY: 102934777(RXRA)
CPIC: 101935365(RXRA)
ACS: 100561503(rxra)
PVT: 110089296(RXRA)
PBI: 103051303
PMUR: 107292619
GJA: 107115577(RXRA)
XLA: 108699915 378685(rxra.L)
XTR: 100487877(rxra)
NPR: 108795632(RXRA)
DRE: 30464(rxrga) 555578(rxraa)
TRU: 101062011(rxra) 101064914
LCO: 104922748 104924865(rxra)
NCC: 104965568
MZE: 101473356(rxra)
OLA: 100125504(rxra) 100125506
XMA: 102218909 102234004(rxra)
XCO: 114140512 114149501(rxra)
PRET: 103474009(rxra) 103478548
NFU: 107396340(rxra)
KMR: 108241374(rxra)
CSEM: 103388487 103389488(rxra)
LCF: 108880296(rxra) 108891119
SDU: 111237507(rxra) 111238777
LCM: 102345799(RXRA) 102351060
CMK: 103184713(rxra) 103184778
CIN: 778746(rxr)
SPU: 579018
APLC: 110976278
SKO: 100329058
API: 100164958(Usp)
DNX: 107165733
AGS: 114130882
BTAB: 109032681
CLEC: 106665686
ZNE: 110832159
DPTE: 113797476
TSP: Tsp_03230
PCAN: 112574661
MYI: 110463383
OBI: 106868437
LAK: 106175291
SHX: MS3_01783
EPA: 110238100
PDAM: 113671412
SPIS: 111324734
 » show all
TaxonomyKoalaUniProt
Reference
PMID:2159111
  Authors
Mangelsdorf DJ, Ong ES, Dyck JA, Evans RM
  Title
Nuclear receptor that identifies a novel retinoic acid response pathway.
  Journal
Nature 345:224-9 (1990)
DOI:10.1038/345224a0
  Sequence
[hsa:6256]
Reference
  Authors
Lefebvre P, Benomar Y, Staels B
  Title
Retinoid X receptors: common heterodimerization partners with distinct functions.
  Journal
Trends Endocrinol Metab 21:676-83 (2010)
DOI:10.1016/j.tem.2010.06.009
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