KEGG   ORTHOLOGY: K08675Help
Entry
K08675                      KO                                     

Name
PRSS15, PIM1
Definition
ATP-dependent Lon protease [EC:3.4.21.53]
Disease
H01824  CODAS syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors
    K08675  PRSS15, PIM1; ATP-dependent Lon protease
  09182 Protein families: genetic information processing
   03029 Mitochondrial biogenesis
    K08675  PRSS15, PIM1; ATP-dependent Lon protease
Enzymes [BR:ko01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.21  Serine endopeptidases
    3.4.21.53  endopeptidase La
     K08675  PRSS15, PIM1; ATP-dependent Lon protease
Peptidases and inhibitors [BR:ko01002]
 Serine peptidases
  Family S16: lon protease family
   K08675  PRSS15, PIM1; ATP-dependent Lon protease
Mitochondrial biogenesis [BR:ko03029]
 Mitochondrial quality control factors
  Regulator of mitochondrial biogenesis
   Other regulator of mitochondrial biogenesis
    K08675  PRSS15, PIM1; ATP-dependent Lon protease
BRITE hierarchy
Genes
HSA: 9361(LONP1)
PTR: 455623(LONP1)
PPS: 100976253(LONP1)
PON: 100461951(LONP1)
NLE: 100590941(LONP1)
MCC: 700284(LONP1)
MCF: 101866482(LONP1)
CSAB: 103233746(LONP1)
RRO: 104665476(LONP1)
RBB: 108512096(LONP1)
CJC: 100408135(LONP1)
SBQ: 101042739(LONP1)
MMU: 74142(Lonp1)
MCAL: 110284091(Lonp1)
MPAH: 110335615(Lonp1)
RNO: 170916(Lonp1)
MUN: 110546250(Lonp1)
CGE: 100771385(Lonp1)
NGI: 103737205(Lonp1)
HGL: 101710908(Lonp1)
CCAN: 109688221(Lonp1)
TUP: 102469312(LONP1)
CFA: 611425(LONP1)
VVP: 112935610(LONP1)
AML: 100468447(LONP1)
UAH: 113242858(LONP1)
ORO: 101367221(LONP1)
ELK: 111161696
FCA: 101093417(LONP1)
PPAD: 109255924(LONP1)
AJU: 106975449(LONP1)
BTA: 510796(LONP1)
BIU: 109561716(LONP1)
BBUB: 102413839(LONP1)
CHX: 102182026(LONP1)
OAS: 101109965(LONP1)
SSC: 100511917(LONP1)
CFR: 102505491(LONP1)
CDK: 105091759(LONP1)
LVE: 103076731(LONP1)
OOR: 101275103(LONP1)
DLE: 111165960(LONP1)
PCAD: 102980645(LONP1)
ECB: 100065045(LONP1)
EAI: 106832338(LONP1)
MNA: 107525668(LONP1)
HAI: 109388581(LONP1)
PALE: 102877695(LONP1)
RAY: 107510942(LONP1)
LAV: 100664035(LONP1)
TMU: 101354513
MDO: 100024990(LONP1)
SHR: 100926021(LONP1)
PCW: 110197391(LONP1)
OAA: 100074993(LONP1)
GGA: 768942(LONP1)
MGP: 100538450(LONP1)
CJO: 107325567(LONP1)
TGU: 100221382(LONP1)
CPIC: 101938534(LONP1)
PBI: 103066216(LONP1)
XLA: 108712696(lonp1.L)
XTR: 100492505(lonp1)
NPR: 108789637(LONP1)
DRE: 563257(lonp1)
SRX: 107744642
SGH: 107548847
PHYP: 113543618(lonp1)
AMEX: 103026089(lonp1)
EEE: 113591724(lonp1)
TRU: 101061296(lonp1)
LCO: 104927279(lonp1)
MZE: 101475120(lonp1)
ONL: 100708000(lonp1)
XMA: 102219683(lonp1)
XCO: 114151434(lonp1)
PRET: 103464218(lonp1)
NFU: 107394993(lonp1)
KMR: 108246953(lonp1)
ALIM: 106517295(lonp1)
AOCE: 111564042(lonp1)
CSEM: 103396817(lonp1)
LCF: 108900694(lonp1)
SDU: 111240094(lonp1)
SLAL: 111660174(lonp1)
HCQ: 109516958(lonp1)
MALB: 109972174
SASA: 106560597(lonp1)
OTW: 112251435(lonp1)
SALP: 111975733
ELS: 105031384(lonp1)
SFM: 108921380(lonp1)
PKI: 111847564(lonp1)
LCM: 102359473(LONP1)
CMK: 103188337(lonp1)
RTP: 109915921(lonp1)
CIN: 100178941
SPU: 100889553
DME: Dmel_CG8798(Lon)
DER: 6545346
DSI: Dsimw501_GD12266(Dsim_GD12266)
DSR: 110189879
DWI: 6643034
DNV: 108650987
DHE: 111605069
AAG: 5568011
AALB: 109399481
AME: 409459
BIM: 100748909
BTER: 100645793
CCAL: 108628100
OBB: 114882760
NVI: 100119946
TCA: 661788
DPA: 109540187
ATD: 109599976
NVL: 108560099
API: 100162246
DNX: 107169899
AGS: 114125525
RMD: 113550433
CEL: CELE_C34B2.6(lonp-1) CELE_Y75B8A.4(lonp-2)
CBR: CBG12802
BMY: Bm1_18860
SHX: MS3_03774
ATH: AT3G05780(LON3) AT3G05790(LON4) AT5G26860(LON1)
TCC: 18600571
GAB: 108469996
VRA: 106772262
VAR: 108325921
VUN: 114191692
CCAJ: 109819213
CAM: 101510578
LJA: Lj0g3v0183909.1(Lj0g3v0183909.1)
ADU: 107465214
AIP: 107618105
PXB: 103962312
ZJU: 107407834
MCHA: 111023269
CMAX: 111465425
CMOS: 111444355
CPEP: 111798716
JCU: 105647420
HBR: 110641817
MESC: 110621016
JRE: 108981232
QSU: 112028757
VVI: 100254508
BDI: 100844749
ATS: 109738385(LOC109738385)
SBI: 8077511
ZMA: 732810(LON2)
SITA: 101775616
SCE: YBL022C(PIM1)
CAL: CAALFM_CR04340WA(PIM1)
NCR: NCU05261
NTE: NEUTE1DRAFT61761(NEUTE1DRAFT_61761)
BFU: BCIN_07g06160(Bcpim1)
MBE: MBM_01738
ANI: AN6193.2
ANG: ANI_1_516024(An02g03760)
ABE: ARB_01104
TVE: TRV_04140
SPO: SPAC22F3.06c(lon1)
CNB: CNBD2440
MGL: MGL_4002
TAN: TA12745
TPV: TP02_0361
BBO: BBOV_III006020(17.m07531)
PPU: PP_1443(lon-I)
PST: PSPTO_4210(lon-2)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Bota DA, Davies KJ
  Title
Lon protease preferentially degrades oxidized mitochondrial aconitase by an ATP-stimulated mechanism.
  Journal
Nat Cell Biol 4:674-80 (2002)
DOI:10.1038/ncb836
Reference
  Authors
Lu B, Yadav S, Shah PG, Liu T, Tian B, Pukszta S, Villaluna N, Kutejova E, Newlon CS, Santos JH, Suzuki CK
  Title
Roles for the human ATP-dependent Lon protease in mitochondrial DNA maintenance.
  Journal
J Biol Chem 282:17363-74 (2007)
DOI:10.1074/jbc.M611540200
  Sequence
[hsa:9361]
LinkDB All DBs

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