KEGG   ORTHOLOGY: K08774Help
Entry
K08774                      KO                                     

Name
TGFA
Definition
transforming growth factor, alpha
Pathway
ko01521  EGFR tyrosine kinase inhibitor resistance
ko04010  MAPK signaling pathway
ko04012  ErbB signaling pathway
ko04014  Ras signaling pathway
ko04151  PI3K-Akt signaling pathway
ko04915  Estrogen signaling pathway
ko05200  Pathways in cancer
ko05210  Colorectal cancer
ko05211  Renal cell carcinoma
ko05212  Pancreatic cancer
ko05214  Glioma
ko05215  Prostate cancer
ko05223  Non-small cell lung cancer
ko05225  Hepatocellular carcinoma
Disease
H00020  Colorectal cancer
H00048  Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    K08774  TGFA; transforming growth factor, alpha
   04010 MAPK signaling pathway
    K08774  TGFA; transforming growth factor, alpha
   04012 ErbB signaling pathway
    K08774  TGFA; transforming growth factor, alpha
   04151 PI3K-Akt signaling pathway
    K08774  TGFA; transforming growth factor, alpha
 09150 Organismal Systems
  09152 Endocrine system
   04915 Estrogen signaling pathway
    K08774  TGFA; transforming growth factor, alpha
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K08774  TGFA; transforming growth factor, alpha
  09162 Cancer: specific types
   05210 Colorectal cancer
    K08774  TGFA; transforming growth factor, alpha
   05212 Pancreatic cancer
    K08774  TGFA; transforming growth factor, alpha
   05225 Hepatocellular carcinoma
    K08774  TGFA; transforming growth factor, alpha
   05214 Glioma
    K08774  TGFA; transforming growth factor, alpha
   05211 Renal cell carcinoma
    K08774  TGFA; transforming growth factor, alpha
   05215 Prostate cancer
    K08774  TGFA; transforming growth factor, alpha
   05223 Non-small cell lung cancer
    K08774  TGFA; transforming growth factor, alpha
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    K08774  TGFA; transforming growth factor, alpha
BRITE hierarchy
Other DBs
GO: 0005155
Genes
HSA: 7039(TGFA)
PPS: 100973153(TGFA)
GGO: 101140326(TGFA)
PON: 100172994(TGFA)
NLE: 100607585(TGFA)
MCC: 613031(TGFA)
MCF: 102145541(TGFA)
CSAB: 103220091(TGFA)
RRO: 104661322(TGFA)
RBB: 108524582(TGFA)
CJC: 100402888(TGFA)
SBQ: 101045311(TGFA)
MMU: 21802(Tgfa)
MCAL: 110295684(Tgfa)
MPAH: 110316577(Tgfa)
RNO: 24827(Tgfa)
MUN: 110547163(Tgfa)
CGE: 100754730(Tgfa)
NGI: 103725901(Tgfa)
HGL: 101723712(Tgfa)
CCAN: 109701504(Tgfa)
OCU: 100009482(TGFA)
TUP: 102497817(TGFA)
CFA: 403431(TGFA)
AML: 100467724(TGFA)
UMR: 103671814(TGFA)
UAH: 113268295(TGFA)
ORO: 101384783(TGFA)
FCA: 101094921(TGFA)
PTG: 102956554(TGFA)
AJU: 106967765(TGFA)
BTA: 540388(TGFA)
BOM: 102264981(TGFA)
BIU: 109565956(TGFA)
BBUB: 102406217(TGFA)
PHD: 102339351(TGFA)
CHX: 102185926(TGFA)
OAS: 101106508(TGFA)
SSC: 397484(TGFA)
CFR: 102506694(TGFA)
CDK: 105088937(TGFA)
BACU: 103010563(TGFA)
LVE: 103076982(TGFA)
OOR: 101281424(TGFA)
DLE: 111167945(TGFA)
PCAD: 102973542(TGFA)
ECB: 100060423(TGFA)
EPZ: 103547583(TGFA)
EAI: 106828311(TGFA)
MYB: 102262078(TGFA)
MYD: 102768972(TGFA)
HAI: 109385384(TGFA)
RSS: 109438669(TGFA)
DRO: 112303034(TGFA)
PALE: 102887662(TGFA)
RAY: 107519111(TGFA)
LAV: 100665332(TGFA)
TMU: 101355918
MDO: 100032790(TGFA)
SHR: 100928770(TGFA)
PCW: 110207627(TGFA)
OAA: 100090413(TGFA)
GGA: 414743(TGFA)
MGP: 100542303(TGFA)
CJO: 107323712(TGFA)
NMEL: 110387213(TGFA)
ACYG: 106046246(TGFA)
TGU: 100222335(TGFA)
LSR: 110478619(TGFA)
GFR: 102032034
PHI: 102109017(TGFA)
CCAE: 111938749(TGFA)
ETL: 114066430(TGFA)
FPG: 101917220(SNRPG)
FCH: 102057058(TGFA)
CLV: 102097060(TGFA)
AAM: 106490250(TGFA)
ASN: 102379226(TGFA)
AMJ: 102570675(TGFA)
PSS: 102445585(TGFA)
CMY: 102947389(TGFA)
CPIC: 101939693(TGFA)
PVT: 110072211(TGFA)
PBI: 103053928(TGFA)
PMUR: 107283236(TGFA)
GJA: 107118762(TGFA)
XLA: 108696277(LOC733728.L) 108712769(tgfa.S) 496037(tgfa.L)
XTR: 100485434(tgfa) 733728
NPR: 108785348(TGFA) 108802996
DRE: 100034402(tgfa)
SGH: 107568177(tgfa)
IPU: 108271731
PHYP: 113533017
AMEX: 103044858
EEE: 113575949
TRU: 101076984
LCO: 104931327
NCC: 104955540(tgfa)
MZE: 101486967(tgfa)
OLA: 101166855
XMA: 102232831(tgfa)
XCO: 114134863
PRET: 103464582(tgfa)
NFU: 107385163
KMR: 108231156(tgfa)
AOCE: 111575277(tgfa)
CSEM: 103385772
POV: 109638459
LCF: 108889336
SDU: 111222913
HCQ: 109531425(tgfa)
BPEC: 110168760
MALB: 109958999
ELS: 105016898
SFM: 108920173(tgfa)
PKI: 111848546(tgfa)
LCM: 102367184(TGFA)
CMK: 103185867 103190258(tgfa)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:6088071
  Authors
Derynck R, Roberts AB, Winkler ME, Chen EY, Goeddel DV
  Title
Human transforming growth factor-alpha: precursor structure and expression in E. coli.
  Journal
Cell 38:287-97 (1984)
DOI:10.1016/0092-8674(84)90550-6
  Sequence
[hsa:7039]
LinkDB All DBs

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