KEGG   ORTHOLOGY: K09849Help
Entry
K09849                      KO                                     

Name
TRAF5
Definition
TNF receptor-associated factor 5
Pathway
ko04064  NF-kappa B signaling pathway
ko04217  Necroptosis
ko04621  NOD-like receptor signaling pathway
ko04657  IL-17 signaling pathway
ko04668  TNF signaling pathway
ko05131  Shigellosis
ko05163  Human cytomegalovirus infection
ko05168  Herpes simplex virus 1 infection
ko05169  Epstein-Barr virus infection
ko05170  Human immunodeficiency virus 1 infection
ko05200  Pathways in cancer
ko05203  Viral carcinogenesis
ko05222  Small cell lung cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04064 NF-kappa B signaling pathway
    K09849  TRAF5; TNF receptor-associated factor 5
   04668 TNF signaling pathway
    K09849  TRAF5; TNF receptor-associated factor 5
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    K09849  TRAF5; TNF receptor-associated factor 5
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    K09849  TRAF5; TNF receptor-associated factor 5
   04657 IL-17 signaling pathway
    K09849  TRAF5; TNF receptor-associated factor 5
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K09849  TRAF5; TNF receptor-associated factor 5
   05203 Viral carcinogenesis
    K09849  TRAF5; TNF receptor-associated factor 5
  09162 Cancer: specific types
   05222 Small cell lung cancer
    K09849  TRAF5; TNF receptor-associated factor 5
  09171 Infectious disease: bacterial
   05131 Shigellosis
    K09849  TRAF5; TNF receptor-associated factor 5
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    K09849  TRAF5; TNF receptor-associated factor 5
   05168 Herpes simplex virus 1 infection
    K09849  TRAF5; TNF receptor-associated factor 5
   05163 Human cytomegalovirus infection
    K09849  TRAF5; TNF receptor-associated factor 5
   05169 Epstein-Barr virus infection
    K09849  TRAF5; TNF receptor-associated factor 5
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system
    K09849  TRAF5; TNF receptor-associated factor 5
Ubiquitin system [BR:ko04121]
 Ubiquitin ligases (E3)
  Single Ring-finger type E3
   TRAF proteins
    K09849  TRAF5; TNF receptor-associated factor 5
BRITE hierarchy
Genes
HSA: 7188(TRAF5)
PTR: 457711(TRAF5)
PPS: 100978119(TRAF5)
GGO: 101130440(TRAF5)
PON: 100453867(TRAF5)
NLE: 100601779(TRAF5)
MCC: 711879(TRAF5)
MCF: 102142772(TRAF5)
CSAB: 103230138(TRAF5)
RRO: 104669508(TRAF5)
RBB: 108515877(TRAF5)
CJC: 100388423(TRAF5)
SBQ: 101031994(TRAF5)
MMU: 22033(Traf5)
MCAL: 110296886(Traf5)
MPAH: 110322137(Traf5)
RNO: 684173(Traf5)
MUN: 110566223(Traf5)
CGE: 100760758(Traf5)
NGI: 103727039(Traf5)
HGL: 101704164(Traf5)
CCAN: 109692314(Traf5)
OCU: 100340005(TRAF5)
TUP: 102478124(TRAF5)
CFA: 480019(TRAF5)
VVP: 112907150(TRAF5)
AML: 100475872(TRAF5)
UMR: 103672476(TRAF5)
UAH: 113262665(TRAF5)
ORO: 101373241(TRAF5)
ELK: 111150675
FCA: 101086032(TRAF5)
PTG: 102972430(TRAF5)
PPAD: 109254870(TRAF5)
AJU: 106966776(TRAF5)
BTA: 507234(TRAF5)
BOM: 102266053(TRAF5)
BIU: 109570606(TRAF5)
BBUB: 102413198(TRAF5)
CHX: 102188243(TRAF5)
OAS: 101119408(TRAF5)
SSC: 396616(TRAF5)
CFR: 102507430(TRAF5)
CDK: 105099319(TRAF5)
BACU: 103010499(TRAF5)
LVE: 103075051(TRAF5)
OOR: 101280074(TRAF5)
DLE: 111184706(TRAF5)
PCAD: 102986959(TRAF5)
ECB: 100055119(TRAF5)
EPZ: 103551972(TRAF5)
EAI: 106827146(TRAF5)
MYB: 102243439(TRAF5)
MYD: 102764568(TRAF5)
MNA: 107538857(TRAF5)
HAI: 109379157(TRAF5)
DRO: 112296542(TRAF5)
PALE: 102879730(TRAF5)
RAY: 107521637(TRAF5)
MJV: 108385436(TRAF5)
LAV: 100663885(TRAF5)
TMU: 101358050
MDO: 100022268(TRAF5)
SHR: 100926831(TRAF5)
PCW: 110222706(TRAF5)
OAA: 100078367(TRAF5)
GGA: 374055(TRAF5)
MGP: 100541595(TRAF5)
CJO: 107311111(TRAF5)
NMEL: 110396762(TRAF5)
APLA: 101797384(TRAF5)
ACYG: 106031523(TRAF5)
TGU: 100219054(TRAF5)
LSR: 110479943(TRAF5)
SCAN: 103821528(TRAF5)
GFR: 102042050(TRAF5)
FAB: 101821791(TRAF5)
PHI: 102104462(TRAF5)
PMAJ: 107201904(TRAF5)
CCAE: 111926165(TRAF5)
CCW: 104685651(TRAF5)
ETL: 114066923(TRAF5)
FPG: 101921400(TRAF5)
FCH: 102053015(TRAF5)
CLV: 102088528(TRAF5)
EGZ: 104128738(TRAF5)
NNI: 104019677(TRAF5)
ACUN: 113478255(TRAF5)
PADL: 103922096(TRAF5)
AAM: 106490486(TRAF5)
ASN: 102370403(TRAF5)
AMJ: 102564531(TRAF5)
PSS: 102459505(TRAF5)
CMY: 102929887(TRAF5)
CPIC: 101933745(TRAF5)
ACS: 100555319(traf5)
PVT: 110079501(TRAF5)
PBI: 103064879(TRAF5) 103067755
PMUR: 107288580(TRAF5)
TSR: 106552805(TRAF5)
PMUA: 114594702(TRAF5)
GJA: 107124212(TRAF5)
XLA: 108716445(traf5.L)
XTR: 100491604(traf5)
NPR: 108784349(TRAF5)
DRE: 563887(traf5)
IPU: 108271110
PHYP: 113534779
AMEX: 103031120
EEE: 113569092
LCO: 104936671
NCC: 104947442
MZE: 101481248
ONL: 100697176
OLA: 101170323
KMR: 108249386
AOCE: 111563258
CSEM: 103383406
LCF: 108892171
SDU: 111232930
SLAL: 111649752
MALB: 109971816
SASA: 106564804 106585043(TRAF5)
ELS: 105026840
SFM: 108933531(traf5)
PKI: 111853469(traf5)
LCM: 102355485(TRAF5)
CMK: 103178011(traf5)
RTP: 109920924
VEM: 105567053
ZNE: 110838498
TUT: 107368829
EPA: 110251088
AMIL: 114959668
PDAM: 113671840
SPIS: 111340649
DFA: DFA_02794
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Sun D, Novotny M, Bulek K, Liu C, Li X, Hamilton T
  Title
Treatment with IL-17 prolongs the half-life of chemokine CXCL1 mRNA via the adaptor TRAF5 and the splicing-regulatory factor SF2 (ASF).
  Journal
Nat Immunol 12:853-60 (2011)
DOI:10.1038/ni.2081
Reference
PMID:9511754
  Authors
Mizushima S, Fujita M, Ishida T, Azuma S, Kato K, Hirai M, Otsuka M, Yamamoto T, Inoue J
  Title
Cloning and characterization of a cDNA encoding the human homolog of tumor necrosis factor receptor-associated factor 5 (TRAF5).
  Journal
Gene 207:135-40 (1998)
DOI:10.1016/S0378-1119(97)00616-1
  Sequence
[hsa:7188]
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