KEGG   ORTHOLOGY: K10151Help
Entry
K10151                      KO                                     

Name
CCND2
Definition
G1/S-specific cyclin-D2
Pathway
ko04068  FoxO signaling pathway
ko04110  Cell cycle
ko04115  p53 signaling pathway
ko04151  PI3K-Akt signaling pathway
ko04218  Cellular senescence
ko04310  Wnt signaling pathway
ko04340  Hedgehog signaling pathway
ko04390  Hippo signaling pathway
ko04510  Focal adhesion
ko04630  JAK-STAT signaling pathway
ko04917  Prolactin signaling pathway
ko05162  Measles
ko05165  Human papillomavirus infection
ko05166  Human T-cell leukemia virus 1 infection
ko05169  Epstein-Barr virus infection
ko05200  Pathways in cancer
ko05202  Transcriptional misregulation in cancer
ko05203  Viral carcinogenesis
ko05206  MicroRNAs in cancer
Disease
H00023  Testicular cancer
H01885  Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    K10151  CCND2; G1/S-specific cyclin-D2
   04340 Hedgehog signaling pathway
    K10151  CCND2; G1/S-specific cyclin-D2
   04390 Hippo signaling pathway
    K10151  CCND2; G1/S-specific cyclin-D2
   04630 Jak-STAT signaling pathway
    K10151  CCND2; G1/S-specific cyclin-D2
   04068 FoxO signaling pathway
    K10151  CCND2; G1/S-specific cyclin-D2
   04151 PI3K-Akt signaling pathway
    K10151  CCND2; G1/S-specific cyclin-D2
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    K10151  CCND2; G1/S-specific cyclin-D2
   04115 p53 signaling pathway
    K10151  CCND2; G1/S-specific cyclin-D2
   04218 Cellular senescence
    K10151  CCND2; G1/S-specific cyclin-D2
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    K10151  CCND2; G1/S-specific cyclin-D2
 09150 Organismal Systems
  09152 Endocrine system
   04917 Prolactin signaling pathway
    K10151  CCND2; G1/S-specific cyclin-D2
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K10151  CCND2; G1/S-specific cyclin-D2
   05202 Transcriptional misregulation in cancer
    K10151  CCND2; G1/S-specific cyclin-D2
   05206 MicroRNAs in cancer
    K10151  CCND2; G1/S-specific cyclin-D2
   05203 Viral carcinogenesis
    K10151  CCND2; G1/S-specific cyclin-D2
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K10151  CCND2; G1/S-specific cyclin-D2
   05162 Measles
    K10151  CCND2; G1/S-specific cyclin-D2
   05169 Epstein-Barr virus infection
    K10151  CCND2; G1/S-specific cyclin-D2
   05165 Human papillomavirus infection
    K10151  CCND2; G1/S-specific cyclin-D2
BRITE hierarchy
Genes
HSA: 894(CCND2)
PTR: 747123(CCND2)
PPS: 100990850(CCND2)
GGO: 101139749(CCND2)
PON: 100457978(CCND2)
NLE: 100585770(CCND2)
MCC: 710379(CCND2)
MCF: 102119572(CCND2)
CSAB: 103218410(CCND2)
RRO: 104658979(CCND2)
RBB: 108536489(CCND2)
CJC: 100390172(CCND2)
SBQ: 101049141(CCND2)
MMU: 12444(Ccnd2)
MCAL: 110296334(Ccnd2)
MPAH: 110315929(Ccnd2)
RNO: 64033(Ccnd2)
MUN: 110548628(Ccnd2)
CGE: 100771544(Ccnd2)
NGI: 103727547(Ccnd2)
HGL: 101721480(Ccnd2)
OCU: 100009036(CCND2)
TUP: 102479902(CCND2)
CFA: 611782(CCND2)
VVP: 112917379(CCND2)
AML: 100471517(CCND2)
UMR: 103675743(CCND2)
UAH: 113258003(CCND2)
ORO: 101363193(CCND2)
FCA: 101090950(CCND2)
PTG: 102970259(CCND2)
AJU: 106965383(CCND2)
BTA: 615414(CCND2)
BOM: 102272576(CCND2)
BIU: 109559745(CCND2)
BBUB: 102410004(CCND2)
PHD: 102326040(CCND2)
CHX: 102180657(CCND2)
OAS: 100147799(CCND2)
SSC: 397162(CCND2)
CDK: 105091327(CCND2)
BACU: 103002964(CCND2)
LVE: 103077970(CCND2)
OOR: 101274693(CCND2)
DLE: 111176638(CCND2)
PCAD: 102981679(CCND2)
ECB: 100051150(CCND2)
EPZ: 103567717(CCND2)
EAI: 106831500(CCND2)
MYB: 102254218(CCND2)
MYD: 102755701(CCND2)
MNA: 107538904(CCND2)
HAI: 109392488(CCND2)
RSS: 109461009(CCND2)
DRO: 112312821(CCND2)
PALE: 102892640(CCND2)
RAY: 107513450(CCND2)
LAV: 100668070(CCND2)
TMU: 101351510
MDO: 100016259(CCND2)
PCW: 110218698(CCND2)
OAA: 100088940(CCND2)
GGA: 374047(CCND2)
MGP: 100550222(CCND2) 104909362
CJO: 107318017(CCND2)
NMEL: 110390646(CCND2)
APLA: 101802600(CCND2)
ACYG: 106046294(CCND2)
TGU: 100224096(CCND2)
LSR: 110479030(CCND2)
SCAN: 103819603(CCND2)
GFR: 102034688(CCND2)
FAB: 101818224(CCND2)
PHI: 102114518(CCND2)
PMAJ: 107204709(CCND2)
CCAE: 111930045(CCND2)
CCW: 104696177(CCND2)
ETL: 114067087(CCND2)
FPG: 101920354(CCND2)
FCH: 102053549(CCND2)
CLV: 102093196(CCND2)
EGZ: 104124210(CCND2)
NNI: 104021822(CCND2)
ACUN: 113475855
PADL: 103917223(CCND2)
AAM: 106489562(CCND2)
AMJ: 102564576(CCND2)
PSS: 102462674(CCND2)
CMY: 102931445(CCND2)
CPIC: 101939404(CCND2)
GJA: 107110411(CCND2)
XLA: 373667(ccnd2.L) 734882(ccnd2.S)
XTR: 100038071(ccnd2)
NPR: 108788361(CCND2)
DRE: 799608(ccnd2a)
IPU: 100528326(ccnd2) 108279704(CCND2) 108281084(ccnd3)
AMEX: 103031397(ccnd2) 103045792(ccnd3) 111193357
KMR: 108233174 108235802(ccnd3) 108237544(ccnd2)
CSEM: 103379657 103382708(ccnd2) 103385889(ccnd3) 103392544
MALB: 109961831(ccnd2) 109963107 109964433(ccnd3) 109969706
LCM: 102345953 102351286(CCND2)
CMK: 103182468(ccnd3) 103185578(ccnd2)
CIN: 100186373
SKO: 100303589(ccnd)
DME: Dmel_CG9096(CycD)
DER: 6550709
DSI: Dsimw501_GD15773(Dsim_GD15773)
DPE: 6603470
DWI: 6652925
DNV: 108658144
LCQ: 111677893
AAG: 5575093
AME: 413183
BIM: 100744328
BTER: 100642333
SOC: 105196203
MPHA: 105830325
AEC: 105149790
ACEP: 105619259
PBAR: 105427311
VEM: 105565318
HST: 105191023
DQU: 106748961
CFO: 105248357
PGC: 109855101
OBO: 105284703
PCF: 106790317
NVI: 100117434(cycD)
MDL: 103571676
TCA: 663226
DPA: 109541632
BMOR: 100862781(cycD)
PMAC: 106708805
PRAP: 110996554
HAW: 110372374
TNL: 113508375
PXY: 105385267
DNX: 107168411
BTAB: 109039503
CLEC: 106666256
FCD: 110851356
DPTE: 113798117
CEL: CELE_Y38F1A.5(cyd-1)
CBR: CBG02768(Cbr-cyd-1)
BMY: Bm1_02025
PCAN: 112566123
CRG: 105330764
OBI: 106878898
LAK: 106173892
SHX: MS3_06539
EGL: EGR_02547
EPA: 110247806
ADF: 107334967
PDAM: 113677260
SPIS: 111345418
HMG: 100198325
 » show all
TaxonomyKoalaUniProt
Reference
PMID:1386336
  Authors
Xiong Y, Menninger J, Beach D, Ward DC
  Title
Molecular cloning and chromosomal mapping of CCND genes encoding human D-type cyclins.
  Journal
Genomics 13:575-84 (1992)
DOI:10.1016/0888-7543(92)90127-E
  Sequence
[hsa:894]
Reference
PMID:9178893
  Authors
Sweeney KJ, Sarcevic B, Sutherland RL, Musgrove EA
  Title
Cyclin D2 activates Cdk2 in preference to Cdk4 in human breast epithelial cells.
  Journal
Oncogene 14:1329-40 (1997)
DOI:10.1038/sj.onc.1200951
  Sequence
[hsa:894]
Reference
  Authors
Jena N, Deng M, Sicinska E, Sicinski P, Daley GQ
  Title
Critical role for cyclin D2 in BCR/ABL-induced proliferation of hematopoietic cells.
  Journal
Cancer Res 62:535-41 (2002)
  Sequence
[mmu:12444]
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