KEGG   ORTHOLOGY: K10159
Entry
K10159                      KO                                     

Name
TLR2, CD282
Definition
toll-like receptor 2
Pathway
ko04145  Phagosome
ko04151  PI3K-Akt signaling pathway
ko04613  Neutrophil extracellular trap formation
ko04620  Toll-like receptor signaling pathway
ko05132  Salmonella infection
ko05134  Legionellosis
ko05140  Leishmaniasis
ko05142  Chagas disease
ko05144  Malaria
ko05145  Toxoplasmosis
ko05146  Amoebiasis
ko05152  Tuberculosis
ko05161  Hepatitis B
ko05162  Measles
ko05168  Herpes simplex virus 1 infection
ko05169  Epstein-Barr virus infection
ko05170  Human immunodeficiency virus 1 infection
ko05171  Coronavirus disease - COVID-19
ko05205  Proteoglycans in cancer
ko05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
ko05321  Inflammatory bowel disease
ko05323  Rheumatoid arthritis
Disease
H00344  Leprosy
H01358  Atopic dermatitis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    K10159  TLR2, CD282; toll-like receptor 2
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    K10159  TLR2, CD282; toll-like receptor 2
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    K10159  TLR2, CD282; toll-like receptor 2
   04620 Toll-like receptor signaling pathway
    K10159  TLR2, CD282; toll-like receptor 2
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    K10159  TLR2, CD282; toll-like receptor 2
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    K10159  TLR2, CD282; toll-like receptor 2
  09163 Immune disease
   05323 Rheumatoid arthritis
    K10159  TLR2, CD282; toll-like receptor 2
   05321 Inflammatory bowel disease
    K10159  TLR2, CD282; toll-like receptor 2
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    K10159  TLR2, CD282; toll-like receptor 2
   05134 Legionellosis
    K10159  TLR2, CD282; toll-like receptor 2
   05152 Tuberculosis
    K10159  TLR2, CD282; toll-like receptor 2
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    K10159  TLR2, CD282; toll-like receptor 2
   05161 Hepatitis B
    K10159  TLR2, CD282; toll-like receptor 2
   05171 Coronavirus disease - COVID-19
    K10159  TLR2, CD282; toll-like receptor 2
   05162 Measles
    K10159  TLR2, CD282; toll-like receptor 2
   05168 Herpes simplex virus 1 infection
    K10159  TLR2, CD282; toll-like receptor 2
   05169 Epstein-Barr virus infection
    K10159  TLR2, CD282; toll-like receptor 2
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    K10159  TLR2, CD282; toll-like receptor 2
   05144 Malaria
    K10159  TLR2, CD282; toll-like receptor 2
   05145 Toxoplasmosis
    K10159  TLR2, CD282; toll-like receptor 2
   05140 Leishmaniasis
    K10159  TLR2, CD282; toll-like receptor 2
   05142 Chagas disease
    K10159  TLR2, CD282; toll-like receptor 2
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K10159  TLR2, CD282; toll-like receptor 2
  09183 Protein families: signaling and cellular processes
   04147 Exosome
    K10159  TLR2, CD282; toll-like receptor 2
   04054 Pattern recognition receptors
    K10159  TLR2, CD282; toll-like receptor 2
   04090 CD molecules
    K10159  TLR2, CD282; toll-like receptor 2
   00536 Glycosaminoglycan binding proteins
    K10159  TLR2, CD282; toll-like receptor 2
Membrane trafficking [BR:ko04131]
 Endocytosis
  Phagocytosis
   Toll-like receptors
    K10159  TLR2, CD282; toll-like receptor 2
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of breast milk
   K10159  TLR2, CD282; toll-like receptor 2
Pattern recognition receptors [BR:ko04054]
 Membrane-bound pattern recognition receptors
  Toll-like receptors
   K10159  TLR2, CD282; toll-like receptor 2
CD molecules [BR:ko04090]
 Proteins
  K10159  CD282, TLR2; toll-like receptor 2
Glycosaminoglycan binding proteins [BR:ko00536]
 Hyaluronan
  Cell surface receptors
   K10159  TLR2, CD282; toll-like receptor 2
Genes
HSA: 7097(TLR2)
PTR: 471325(TLR2)
PPS: 100994768(TLR2)
GGO: 101128447(TLR2)
PON: 100456464(TLR2)
NLE: 100604724(TLR2)
MCC: 574290(TLR2)
MCF: 102146068(TLR2)
CSAB: 103236415
RRO: 104677747(TLR2)
RBB: 108529041(TLR2)
CJC: 100404611(TLR2)
SBQ: 101045472(TLR2)
MMU: 24088(Tlr2)
MCAL: 110291353(Tlr2)
MPAH: 110320724(Tlr2)
RNO: 310553(Tlr2)
MUN: 110541773(Tlr2)
CGE: 100771475(Tlr2)
NGI: 103750991(Tlr2)
HGL: 101724657(Tlr2)
CCAN: 109701180(Tlr2)
OCU: 100009578(TLR2)
TUP: 102482498(TLR2)
CFA: 448807(TLR2)
VVP: 112933419(TLR2)
AML: 100465129(TLR2)
UMR: 103658031
UAH: 113255769(TLR2)
ORO: 101363280(TLR2) 101367407
ELK: 111154734
FCA: 493797(TLR2)
PTG: 102962241 102964242
PPAD: 109262509(TLR2)
AJU: 106982476
BTA: 281534(TLR2)
BOM: 102268835(TLR2)
BIU: 109571498(TLR2)
BBUB: 102397791(TLR2)
CHX: 100860747(TLR2)
OAS: 554262(TLR2)
SSC: 396623(TLR2)
CFR: 102523960(TLR2)
CDK: 105099662(TLR2)
BACU: 102998386(TLR2)
LVE: 103090179
OOR: 101276053
DLE: 111187714(TLR2)
PCAD: 102976342(TLR2)
ECB: 100009701(TLR2)
EPZ: 103553736(TLR2)
EAI: 106821799(TLR2)
MYB: 102256005(TLR2)
MYD: 102761137(TLR2)
MNA: 107525584(TLR2)
HAI: 109382017(TLR2)
DRO: 112312607(TLR2)
PALE: 102893057(TLR2)
RAY: 107510758(TLR2)
MJV: 108390634(TLR2)
LAV: 100654442(TLR2)
TMU: 101342847
MDO: 100024558(TLR2)
SHR: 100932981(TLR2)
PCW: 110213633(TLR2)
OAA: 100081248(TLR2)
GGA: 374141(TLR2A) 769014(TLR2B)
MGP: 104910743 109363679 109363685
CJO: 107313061 107313069
NMEL: 110398324(TLR2)
APLA: 101791786(TLR2) 110351185
ACYG: 106032264(TLR2) 106049058
TGU: 100219691(TLR2)
SCAN: 103826229(TLR2)
GFR: 102034174 102036739 102045171
FAB: 101811742 101811943(TLR2) 101812558
PHI: 102104379 102104560(TLR2) 102106628
PMAJ: 107202976(TLR2)
CCAE: 111927833 111927834
CCW: 104697168(TLR2)
ETL: 114066323(TLR2)
FPG: 101915501 101923386(TLR2) 101923563
FCH: 102051584(TLR2) 102058278
CLV: 102084454 102084767(TLR2)
EGZ: 104126737 104126791(TLR2) 104127978
NNI: 104008501 104014466 104021229(TLR2) 104021230 104022406
ACUN: 113479805 113479806(TLR2)
PADL: 103921773 103921774
AAM: 106491872 106491913
ASN: 102368109(TLR2) 102368346 102383113 102383734 102384063
AMJ: 102569653 102571171(CD14) 102572093(TLR2) 106740518(TLR2)
PSS: 102445063 102457158(TLR2) 102457570 102458059
CMY: 102934124 102943966
CPIC: 101932351(TLR2) 101932616 101937770(CD14) 101939272
ACS: 100553042 100564001(tlr2) 100564196 100564690 103278612 103278613(cd14)
PVT: 110069865 110072767(TLR2) 110082123
PBI: 103049109 103050528 103064827(TLR2)
PMUR: 107283615(CD14) 107288063 107289574(TLR2)
TSR: 106544777(TLR2) 106553961
PMUA: 114586776 114601154(CD14)
GJA: 107107978 107108593(TLR2) 107118830 107119739
XLA: 108699311 108699322 108699606 108700404 108706656 108710847
XTR: 100485512 100485771(tlr2) 100485927 100487973 116409470
NPR: 108788197(TLR2) 108791424 108795015
DRE: 403125(tlr2) 403133(tlr18)
SRX: 107717772 107722930
SANH: 107663243 107689857 107702532(tlr2)
SGH: 107590711 107597981
CCAR: 109060541 109073772 109074587
IPU: 108258959(tlr2) 108272691(TLR18)
PHYP: 113533829 113535686(tlr2)
AMEX: 103042489 103044794 103045101
EEE: 113583650 113589619
TRU: 101068527 101068557(tlr2)
TNG: GSTEN00004567G001
LCO: 104923941 104934739 104938453
NCC: 104943968
MZE: 101463793 101470585 101484533 106675443 106675704
ONL: 100694547(tlr2) 100705953 102076284 102076916(tlr2) 102077009 109202487
OLA: 101155381 101162959 101173259
XMA: 102226787 102227045 102230797
XCO: 114140250 114157991 114158033
PRET: 103460805(tlr2) 103477637 103480941
CVG: 107082271(tlr2) 107082292 107084756
NFU: 107379226 107395103
KMR: 108239773 108243184(tlr18) 108248293(tlr2)
ALIM: 106526902 106529226
AOCE: 111586854(tlr2)
CSEM: 103388693
POV: 109633418 109646959(tlr2)
LCF: 108883170 108885865 108901668(tlr2) 108902352
SDU: 111216599(tlr2) 111222405 111236680 111240019
SLAL: 111668167 111669232
HCQ: 109512204
BPEC: 110160272 110170449
MALB: 109968926
SASA: 106580799 106605325 106608430
OTW: 112229323 112237807
SALP: 111965103 112076105
ELS: 105028681 105030906(tlr2)
SFM: 108926796
PKI: 111838449
LCM: 102350366 102355189 102367073(TLR2)
CMK: 103185476 103185499 103189760
RTP: 109912800 109923613 109928617
CSCU: 111628016
PCAN: 112561167
CRG: 105324722
AMIL: 114952281
PDAM: 113685912
DGT: 114528769
 » show all
Reference
PMID:9596645
  Authors
Chaudhary PM, Ferguson C, Nguyen V, Nguyen O, Massa HF, Eby M, Jasmin A, Trask BJ, Hood L, Nelson PS
  Title
Cloning and characterization of two Toll/Interleukin-1 receptor-like genes TIL3 and TIL4: evidence for a multi-gene receptor family in humans.
  Journal
Blood 91:4020-7 (1998)
  Sequence
[hsa:7097]
Reference
  Authors
Kang JY, Nan X, Jin MS, Youn SJ, Ryu YH, Mah S, Han SH, Lee H, Paik SG, Lee JO
  Title
Recognition of lipopeptide patterns by Toll-like receptor 2-Toll-like receptor 6 heterodimer.
  Journal
Immunity 31:873-84 (2009)
DOI:10.1016/j.immuni.2009.09.018
  Sequence
[mmu:24088]
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