KEGG   ORTHOLOGY: K10163Help
Entry
K10163                      KO                                     

Name
FOXP3, IPEX
Definition
forkhead box P3
Pathway
ko04659  Th17 cell differentiation
ko05321  Inflammatory bowel disease (IBD)
Disease
H00107  Other well-defined immunodeficiency syndromes
H00512  Permanent neonatal diabetes mellitus
H01971  IPEX syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    K10163  FOXP3, IPEX; forkhead box P3
 09160 Human Diseases
  09163 Immune disease
   05321 Inflammatory bowel disease (IBD)
    K10163  FOXP3, IPEX; forkhead box P3
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K10163  FOXP3, IPEX; forkhead box P3
Transcription factors [BR:ko03000]
 Eukaryotic type
  Helix-turn-helix
   Fork head/winged helix other regulators
    K10163  FOXP3, IPEX; forkhead box P3
BRITE hierarchy
Genes
HSA: 50943(FOXP3)
PTR: 740909(FOXP3)
PPS: 100990082(FOXP3)
GGO: 101130276(FOXP3)
PON: 100432872(FOXP3)
NLE: 100606735(FOXP3)
MCC: 574303(FOXP3)
MCF: 102120882(FOXP3)
CSAB: 103231966(FOXP3)
RRO: 104661817(FOXP3)
RBB: 108521365(FOXP3)
CJC: 100408633(FOXP3)
SBQ: 101035423(FOXP3)
MMU: 20371(Foxp3)
MCAL: 110286217(Foxp3)
MPAH: 110313390(Foxp3)
RNO: 317382(Foxp3)
MUN: 110561916(Foxp3)
CGE: 100757421(Foxp3)
NGI: 103741675(Foxp3)
HGL: 101722447(Foxp3)
CCAN: 109697194(Foxp3)
OCU: 100348270(FOXP3)
TUP: 102482059(FOXP3)
CFA: 491876(FOXP3)
VVP: 112907239(FOXP3)
AML: 100467988(FOXP3)
UMR: 103667451(FOXP3)
UAH: 113265955(FOXP3)
ORO: 101365686(FOXP3)
ELK: 111150492
FCA: 100037405(FOXP3)
PTG: 102972991(FOXP3)
PPAD: 109248099(FOXP3)
AJU: 106989015(FOXP3)
BTA: 506053(FOXP3)
BOM: 102285670(FOXP3)
BIU: 109555264(FOXP3)
BBUB: 102405704(FOXP3)
CHX: 102188755(FOXP3)
OAS: 100240742(FOXP3)
SSC: 444998(FOXP3)
CFR: 102505184(FOXP3)
CDK: 105106315(FOXP3)
BACU: 102998254(FOXP3)
LVE: 103083465(FOXP3)
OOR: 101280345(FOXP3)
DLE: 111169472(FOXP3)
PCAD: 102993238(FOXP3)
ECB: 100052226(FOXP3)
EPZ: 103545451(FOXP3)
EAI: 106826960(FOXP3)
MYB: 102259977(FOXP3)
MYD: 102770845(FOXP3)
MNA: 107541386(FOXP3)
HAI: 109374800(FOXP3)
DRO: 112322442(FOXP3)
PALE: 102882840(FOXP3)
RAY: 107515002(FOXP3)
MJV: 108404218(FOXP3)
LAV: 100667999(FOXP3)
TMU: 101361863
MDO: 100019598(FOXP3)
SHR: 100928075(FOXP3)
PCW: 110201010(FOXP3)
OAA: 100075823(FOXP3)
ASN: 102376811(FOXP3)
ACS: 103277757(foxp3)
PVT: 110078611(FOXP3)
PMUA: 114587352(FOXP3)
XLA: 100158268(foxp3.L) 108700514(foxp3.S)
XTR: 100485747(foxp3)
NPR: 108788500(FOXP3)
PHYP: 113529946
AMEX: 103040869(foxp3) 111194604
XMA: 102225546
XCO: 114142250
PRET: 103466967
CVG: 107091006
SFM: 108934796(foxp3)
PKI: 111847802(foxp3)
LCM: 102353004(FOXP3)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Brunkow ME, Jeffery EW, Hjerrild KA, Paeper B, Clark LB, Yasayko SA, Wilkinson JE, Galas D, Ziegler SF, Ramsdell F
  Title
Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse.
  Journal
Nat Genet 27:68-73 (2001)
DOI:10.1038/83784
  Sequence
[hsa:50943]
Reference
  Authors
Mu J, Tai X, Iyer SS, Weissman JD, Singer A, Singer DS
  Title
Regulation of MHC class I expression by Foxp3 and its effect on regulatory T cell function.
  Journal
J Immunol 192:2892-903 (2014)
DOI:10.4049/jimmunol.1302847
  Sequence
[mmu:20371]
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