KEGG   ORTHOLOGY: K11224
Entry
K11224                      KO                                     

Name
STAT5B
Definition
signal transducer and activator of transcription 5B
Pathway
ko04012  ErbB signaling pathway
ko04062  Chemokine signaling pathway
ko04217  Necroptosis
ko04630  JAK-STAT signaling pathway
ko04658  Th1 and Th2 cell differentiation
ko04659  Th17 cell differentiation
ko04917  Prolactin signaling pathway
ko04933  AGE-RAGE signaling pathway in diabetic complications
ko04935  Growth hormone synthesis, secretion and action
ko05161  Hepatitis B
ko05162  Measles
ko05166  Human T-cell leukemia virus 1 infection
ko05200  Pathways in cancer
ko05203  Viral carcinogenesis
ko05220  Chronic myeloid leukemia
ko05221  Acute myeloid leukemia
ko05223  Non-small cell lung cancer
Disease
H00931  Growth hormone insensitivity with immunodeficiency
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    K11224  STAT5B; signal transducer and activator of transcription 5B
   04630 JAK-STAT signaling pathway
    K11224  STAT5B; signal transducer and activator of transcription 5B
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    K11224  STAT5B; signal transducer and activator of transcription 5B
 09150 Organismal Systems
  09151 Immune system
   04658 Th1 and Th2 cell differentiation
    K11224  STAT5B; signal transducer and activator of transcription 5B
   04659 Th17 cell differentiation
    K11224  STAT5B; signal transducer and activator of transcription 5B
   04062 Chemokine signaling pathway
    K11224  STAT5B; signal transducer and activator of transcription 5B
  09152 Endocrine system
   04917 Prolactin signaling pathway
    K11224  STAT5B; signal transducer and activator of transcription 5B
   04935 Growth hormone synthesis, secretion and action
    K11224  STAT5B; signal transducer and activator of transcription 5B
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K11224  STAT5B; signal transducer and activator of transcription 5B
   05203 Viral carcinogenesis
    K11224  STAT5B; signal transducer and activator of transcription 5B
  09162 Cancer: specific types
   05221 Acute myeloid leukemia
    K11224  STAT5B; signal transducer and activator of transcription 5B
   05220 Chronic myeloid leukemia
    K11224  STAT5B; signal transducer and activator of transcription 5B
   05223 Non-small cell lung cancer
    K11224  STAT5B; signal transducer and activator of transcription 5B
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    K11224  STAT5B; signal transducer and activator of transcription 5B
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K11224  STAT5B; signal transducer and activator of transcription 5B
   05161 Hepatitis B
    K11224  STAT5B; signal transducer and activator of transcription 5B
   05162 Measles
    K11224  STAT5B; signal transducer and activator of transcription 5B
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K11224  STAT5B; signal transducer and activator of transcription 5B
Transcription factors [BR:ko03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   STAT
    K11224  STAT5B; signal transducer and activator of transcription 5B
Genes
HSA: 6777(STAT5B)
PTR: 454679(STAT5B)
PPS: 100989105(STAT5B)
GGO: 101128930
PON: 100462537(STAT5B)
NLE: 100602489
MCC: 709760(STAT5B)
MCF: 102127060(STAT5B)
CSAB: 103243413(STAT5B)
RRO: 104680321
RBB: 108518352
CJC: 100388552(STAT5B)
SBQ: 101043203(STAT5B)
MMU: 20851(Stat5b)
MCAL: 110306026(Stat5b)
MPAH: 110331105(Stat5b)
RNO: 25126(Stat5b)
MUN: 110550889
CGE: 100750571
NGI: 103735893(Stat5b)
HGL: 101722721(Stat5b)
CCAN: 109692057
OCU: 100348267(STAT5B)
TUP: 102492323(STAT5B)
CFA: 490969
VVP: 112910740(STAT5B)
AML: 100479246
UMR: 103672570(STAT5B)
UAH: 113265424
ORO: 101372217(STAT5B)
ELK: 111151253
FCA: 101090663(STAT5B)
PTG: 102972489(STAT5B)
PPAD: 109258541
AJU: 106972565
BTA: 282376(STAT5B)
BOM: 102283211(STAT5B)
BIU: 109573773(STAT5B)
BBUB: 102400858
CHX: 102176415(STAT5B)
OAS: 101122961
SSC: 397340(STAT5B)
CFR: 102511001(STAT5B)
CDK: 105090456
LVE: 103082258(STAT5B)
OOR: 101280265(STAT5B)
DLE: 111166483
PCAD: 102994339(STAT5B)
ECB: 100052954
EPZ: 103550391
EAI: 106826362(STAT5B)
MYB: 102241062(STAT5B)
MNA: 107528845
DRO: 112298560(STAT5B)
PALE: 102884882
RAY: 107513822(STAT5B)
MJV: 108388330
LAV: 100669299(STAT5B)
TMU: 101354148
MDO: 100011470(STAT5B)
SHR: 100920307(STAT5B)
PCW: 110198412
OAA: 100092915(STAT5B)
GGA: 395556(STAT5B)
MGP: 100546986
CJO: 107325190
NMEL: 110388528(STAT5B)
APLA: 101790203
ACYG: 106047991
TGU: 100222731
LSR: 110471843
SCAN: 103821589
GFR: 102036670(STAT5B)
FAB: 101808879(STAT5B)
PHI: 102101483(STAT5B)
PMAJ: 107215121
CCAE: 111939998
CCW: 104697815
ETL: 114063604
FPG: 101918263(STAT5B)
FCH: 102053699
CLV: 102098622
EGZ: 104135093
NNI: 104009926
ASN: 102380420
AMJ: 102575674(STAT5B)
CMY: 102941843(STAT5B)
CPIC: 101932204
ACS: 100566752(stat5b)
PVT: 110074911
PBI: 103049078
PMUR: 107282650 107297709 107298083
TSR: 106541154
PMUA: 114583662
GJA: 107111494
XLA: 399176(stat5b.L) 414637(stat5b.S)
XTR: 100495240(stat5b)
NPR: 108788932
DRE: 369197(stat5a) 445474(stat5b)
SRX: 107716464 107727963 107729162 107730981 107755555
SANH: 107653267 107674616 107687020 107690298
SGH: 107551841 107556764 107560759 107568282
CCAR: 109049936 109059663 109071022 109074147 109090548
IPU: 108273804(Stat5b) 108279147(STAT5B)
PHYP: 113528082 113535356
AMEX: 103033010 103042656
EEE: 113581977 113591522
TRU: 101071345
TNG: GSTEN00022043G001
LCO: 104925974 104938972
NCC: 104948337 104952122
MZE: 101468393 101485426
ONL: 100690945 100692331
OLA: 101163082 101168657
XMA: 102226876 102235513
XCO: 114150687 114160262
PRET: 103469404 103482184
CVG: 107087640 107091800
NFU: 107378442 107396992
KMR: 108243804(stat5a) 108245177
ALIM: 106522102 106528084
AOCE: 111565177 111576400
CSEM: 103381659 103393172
POV: 109627022 109634198
LCF: 108876812 108879315 108901182
SDU: 111217479 111237041
SLAL: 111660431 111664358
HCQ: 109513793 109529297
BPEC: 110154167 110159495
MALB: 109964186 109966669
SASA: 100380532(sta5b) 106579144 106607295
OTW: 112223777
SALP: 111977867 111980766
ELS: 105013349 105027628
SFM: 108919537 108941722
PKI: 111856018
LCM: 102348150(STAT5B) 102350580(STAT6)
CMK: 103189177
RTP: 109924857 109929795
BFO: 118403966 118417526
CIN: 778770(stat-b) 778907
SPU: 576433
SKO: 100313741
DME: Dmel_CG4257(Stat92E)
DER: 6553695
DSE: 6619260
DSI: Dsimw501_GD20060(Dsim_GD20060)
DYA: Dyak_GE25067
DSR: 110188679
DPO: Dpse_GA26501
DPE: 6588035
DMN: 108155914
DWI: 111518517 111518527 26528977 26529701 26530204 6649639
DGR: Dgri_GH14167
DMO: Dmoj_GI10538
DAZ: 108615391
DNV: 108653502
DHE: 111595033 115483329
DVI: 6629898
MDE: 101895093
LCQ: 111679071
AGA: AgaP_AGAP000099(STAT2) AgaP_AGAP010423(STAT_ANOGA)
AAG: 5572256
AALB: 109422192
CQU: CpipJ_CPIJ016469 CpipJ_CPIJ016470 CpipJ_CPIJ016471
AME: 413742
BIM: 100743540
BTER: 100647789
CCAL: 108630675
OBB: 114873069
SOC: 105193817
MPHA: 105832515
AEC: 105148183
ACEP: 105624336
PBAR: 105433521
VEM: 105563878
HST: 105184844
DQU: 106749703
CFO: 105254529
LHU: 105672556
PGC: 109854643
OBO: 105281780
PCF: 106789625
NVI: 100121885
CSOL: 105361759
MDL: 103580774
TCA: 657965(Stat)
DPA: 109540291
ATD: 109594135
NVL: 108559383
BMOR: 100302627(Stat)
BMAN: 114244414
DPL: KGM_212956A KGM_212956B
PRAP: 110992522
HAW: 110381656
TNL: 113509063
PXY: 105387686 105395332 105396563
API: 100161101
DNX: 107161813 107165640
AGS: 114122874 114124139
RMD: 113551947 113554657
BTAB: 109041216
CLEC: 106661659 106661660
PHU: Phum_PHUM335200
ZNE: 110830516
FCD: 110847260 110849442 110852141 110852198 110855838 110856878 110857610
DPX: DAPPUDRAFT_97641
PVM: 113830023
ISC: IscW_ISCW005692
TUT: 107366189 107369996
DPTE: 113793271
CSCU: 111623415
PTEP: 107452174
CEL: CELE_Y51H4A.17(sta-1)
CBR: CBG13675(Cbr-sta-1)
BMY: Bm1_36470
LOA: LOAG_04974
NAI: NECAME_09201
TSP: Tsp_04456
HRO: HELRODRAFT_179436
PCAN: 112554412 112574768
MYI: 110460766 110463563 110463564
LAK: 106175814 106177519
EPA: 110233275 110234065
ADF: 107338381
AMIL: 114964117
SPIS: 111328363
HMG: 100206878
TAD: TRIADDRAFT_52438
AQU: 100641588
MBR: MONBRDRAFT_44371
SRE: PTSG_04084
 » show all
Reference
PMID:8732682
  Authors
Silva CM, Lu H, Day RN
  Title
Characterization and cloning of STAT5 from IM-9 cells and its activation by growth hormone.
  Journal
Mol Endocrinol 10:508-18 (1996)
DOI:10.1210/mend.10.5.8732682
  Sequence
[hsa:6777]
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