KEGG   ORTHOLOGY: K11405Help
Entry
K11405                      KO                                     

Name
HDAC8
Definition
histone deacetylase 8 [EC:3.5.1.98]
Pathway
ko05034  Alcoholism
ko05165  Human papillomavirus infection
ko05203  Viral carcinogenesis
Disease
H00631  Cornelia de Lange syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 09160 Human Diseases
  09161 Cancers: Overview
   05203 Viral carcinogenesis
    K11405  HDAC8; histone deacetylase 8
  09165 Substance dependence
   05034 Alcoholism
    K11405  HDAC8; histone deacetylase 8
  09172 Infectious diseases: Viral
   05165 Human papillomavirus infection
    K11405  HDAC8; histone deacetylase 8
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins
    K11405  HDAC8; histone deacetylase 8
Enzymes [BR:ko01000]
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.1  In linear amides
    3.5.1.98  histone deacetylase
     K11405  HDAC8; histone deacetylase 8
Chromosome and associated proteins [BR:ko03036]
 Eukaryotic Type
  Histone modification proteins
   HDACs (histone deacetylases)
    Class I HDACs
     K11405  HDAC8; histone deacetylase 8
BRITE hierarchy
Other DBs
GO: 0004407
Genes
HSA: 55869(HDAC8)
PTR: 465712(HDAC8)
PPS: 100988053(HDAC8)
GGO: 101150249(HDAC8)
PON: 100434761(HDAC8)
NLE: 100587031(HDAC8)
MCC: 699642(HDAC8)
MCF: 102131773(HDAC8)
CSAB: 103232180(HDAC8)
RRO: 104660893 104671474(HDAC8)
RBB: 108514096 108527707(HDAC8)
CJC: 100396535(HDAC8)
SBQ: 101040990(HDAC8)
MMU: 70315(Hdac8)
RNO: 363481(Hdac8)
CGE: 100765184
NGI: 103751938(Cited1)
HGL: 101697998(Hdac8)
OCU: 100352038(HDAC8)
TUP: 102484908(HDAC8)
CFA: 480957(HDAC8)
AML: 100480623(HDAC8)
UMR: 103680190(HDAC8)
ORO: 101367808(HDAC8) 101382725
FCA: 101096383(HDAC8)
PTG: 102959505(HDAC8)
AJU: 106982392(HDAC8)
BTA: 540666(HDAC8)
BOM: 102270486(HDAC8)
PHD: 102340610(HDAC8)
CHX: 102184131(HDAC8) 108633221
OAS: 101110121(HDAC8)
SSC: 100625846(HDAC8)
CFR: 102505871(HDAC8)
CDK: 105098583(HDAC8)
BACU: 103005377(HDAC8) 103017578
LVE: 103078231(HDAC8)
OOR: 101276416(HDAC8)
ECB: 100052401(HDAC8)
EPZ: 103563223(HDAC8)
EAI: 106835298(HDAC8)
HAI: 109374770(HDAC8)
RSS: 109455995(HDAC8)
PALE: 102892497(HDAC8)
LAV: 100662291(HDAC8)
TMU: 101343522
MDO: 100618462(HDAC8)
SHR: 100913510(HDAC8)
OAA: 100079804(HDAC8)
GGA: 422182(HDAC8)
MGP: 100542785(HDAC8)
CJO: 107312522(HDAC8)
APLA: 101793806(HDAC8)
ACYG: 106049533(HDAC8)
TGU: 100219810(HDAC8)
GFR: 102043759(HDAC8)
FAB: 101807442(HDAC8)
PHI: 102111947(HDAC8)
PMAJ: 107203764(HDAC8)
CCAE: 111929292(HDAC8)
CCW: 104691577(HDAC8)
FPG: 101910931(HDAC8)
FCH: 102050152(HDAC8)
CLV: 102088526(HDAC8)
EGZ: 104133014(HDAC8)
AAM: 106497411(HDAC8)
ASN: 102375867(HDAC8)
PSS: 102447836(HDAC8)
CMY: 102947739(HDAC8)
CPIC: 101943033(HDAC8)
ACS: 100556612(hdac8)
PVT: 110080216(HDAC8)
PBI: 103065493(HDAC8)
GJA: 107108500(HDAC8)
XLA: 444137(hdac8.L)
XTR: 100145561(hdac8)
NPR: 108802990(HDAC8)
DRE: 406740(hdac8)
SGH: 107557496 107596466(hdac8)
CCAR: 109093625 109094311(hdac8)
IPU: 108267424(hdac8)
AMEX: 103047773(hdac8)
TRU: 101070514(hdac8)
MZE: 101473694(hdac8)
OLA: 101169816(hdac8)
XMA: 102234196(hdac8)
PRET: 103480413(hdac8)
NFU: 107377009(hdac8)
KMR: 108250384(hdac8)
CSEM: 103386271(hdac8)
LCF: 108902093(hdac8)
SDU: 111233461(hdac8)
HCQ: 109516507(hdac8)
BPEC: 110153879(hdac8)
MALB: 109973873(hdac8)
SASA: 106578052 106609057(hdac8)
OTW: 112214503(hdac8)
ELS: 105028222(hdac8)
SFM: 108922873(hdac8)
LCM: 102346366(HDAC8)
CMK: 103177112(hdac8)
CIN: 100175490
SPU: 586295
APLC: 110984510
SKO: 100373017
MDE: 101895615
TCA: 659641
DPA: 109542437
NVL: 108558602
BMOR: 101738400
PMAC: 106709108
PRAP: 111004393
HAW: 110370940
DNX: 107164905
CLEC: 106662884
ZNE: 110830570
FCD: 110844525
CRG: 105329992
OBI: 106874142
SHX: MS3_04161
EGL: EGR_08567
EPA: 110249971
ADF: 107356625
HMG: 100213777
AQU: 100639815
LBC: LACBIDRAFT_310201(HDA16205)
ABP: AGABI1DRAFT102828(AGABI1DRAFT_102828)
ABV: AGABI2DRAFT152937(AGABI2DRAFT_152937)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Yamauchi Y, Boukari H, Banerjee I, Sbalzarini IF, Horvath P, Helenius A
  Title
Histone deacetylase 8 is required for centrosome cohesion and influenza A virus entry.
  Journal
PLoS Pathog 7:e1002316 (2011)
DOI:10.1371/journal.ppat.1002316
  Sequence
[hsa:55869]
Reference
  Authors
Hu E, Chen Z, Fredrickson T, Zhu Y, Kirkpatrick R, Zhang GF, Johanson K, Sung CM, Liu R, Winkler J
  Title
Cloning and characterization of a novel human class I histone deacetylase that functions as a transcription repressor.
  Journal
J Biol Chem 275:15254-64 (2000)
DOI:10.1074/jbc.M908988199
  Sequence
[hsa:55869]
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