KEGG   ORTHOLOGY: K11406Help
Entry
K11406                      KO                                     

Name
HDAC4_5
Definition
histone deacetylase 4/5 [EC:3.5.1.98]
Pathway
ko04371  Apelin signaling pathway
ko05034  Alcoholism
ko05165  Human papillomavirus infection
ko05169  Epstein-Barr virus infection
ko05203  Viral carcinogenesis
Disease
H00561  Brachydactyly-mental retardation syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04371 Apelin signaling pathway
    K11406  HDAC4_5; histone deacetylase 4/5
 09160 Human Diseases
  09161 Cancers
   05203 Viral carcinogenesis
    K11406  HDAC4_5; histone deacetylase 4/5
  09164 Substance dependence
   05034 Alcoholism
    K11406  HDAC4_5; histone deacetylase 4/5
  09167 Infectious diseases
   05169 Epstein-Barr virus infection
    K11406  HDAC4_5; histone deacetylase 4/5
   05165 Human papillomavirus infection
    K11406  HDAC4_5; histone deacetylase 4/5
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins
    K11406  HDAC4_5; histone deacetylase 4/5
Enzymes [BR:ko01000]
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.1  In linear amides
    3.5.1.98  histone deacetylase
     K11406  HDAC4_5; histone deacetylase 4/5
Chromosome and associated proteins [BR:ko03036]
 Eukaryotic Type
  Histone modification proteins
   HDACs (histone deacetylases)
    Class II HDACs
     K11406  HDAC4_5; histone deacetylase 4/5
BRITE hierarchy
Other DBs
GO: 0004407
Genes
HSA: 10014(HDAC5) 9759(HDAC4)
PTR: 454721(HDAC5) 460060(HDAC4)
PPS: 100970870(HDAC4) 100985135(HDAC5)
GGO: 101128693(HDAC5) 101142824(HDAC4)
PON: 100440788(HDAC4) 100458256(HDAC5)
NLE: 100581124(HDAC4) 100585277(HDAC5)
MCC: 710605(HDAC4) 710797 711456(HDAC5)
MCF: 102115906(HDAC4) 102140055(HDAC5)
CSAB: 103218195(HDAC4) 103243334(HDAC5)
RRO: 104654705(HDAC5) 104660448(HDAC4)
RBB: 108531930(HDAC4) 108532177(HDAC5)
CJC: 100386059(HDAC4) 100400747(HDAC5)
SBQ: 101036245(HDAC4) 101048948(HDAC5)
MMU: 15184(Hdac5) 208727(Hdac4)
RNO: 363287(Hdac4) 84580(Hdac5)
CGE: 100689350(Hdac5) 100767877(Hdac4)
NGI: 103730826(Hdac4) 103738280(Hdac5)
HGL: 101696612(Hdac4) 101721186(Hdac5)
OCU: 100338458(HDAC4) 100355860(HDAC7) 100356004(PICK1) 100358981(HDAC5) 103347301
TUP: 102481827(HDAC5) 102490757(HDAC4)
CFA: 490941(HDAC5) 607662(HDAC4)
AML: 100468249(HDAC5) 100478591(HDAC4)
UMR: 103662823(HDAC4) 103665860(HDAC5)
ORO: 101372422(HDAC4) 101374137(HDAC5)
FCA: 101093384(HDAC4) 101098019(HDAC5)
PTG: 102960966(HDAC5) 102963015(HDAC4)
AJU: 106967107(HDAC4) 106974278(HDAC5)
BTA: 504242(HDAC5) 517559(HDAC4)
BOM: 102271862(HDAC5) 102282588(HDAC4)
BIU: 109556936(HDAC4) 109573873(HDAC5)
PHD: 102335385(HDAC4) 102344448(HDAC5)
CHX: 102180254(HDAC5) 102187736(HDAC4)
OAS: 101108012(HDAC4) 101113686(HDAC5)
SSC: 100515165(HDAC5) 100624050(HDAC4)
CFR: 102503564(HDAC4) 102514257(HDAC5) 106730661
CDK: 105101051(HDAC5) 105103240(HDAC4)
BACU: 103005269(HDAC5) 103006122(HDAC4)
LVE: 103070550(HDAC5) 103079661(HDAC4)
OOR: 101271394(HDAC4) 101280818(HDAC5)
ECB: 100051252(HDAC5) 100067014(HDAC4)
EPZ: 103551196(HDAC5) 103555986(HDAC4)
EAI: 106832203(HDAC4) 106836446(HDAC5)
MYB: 102246168(HDAC4) 102247726(HDAC5)
MYD: 102752529(HDAC5) 102760146(HDAC4)
HAI: 109374070(HDAC4) 109394999(HDAC5)
RSS: 109434612(HDAC4) 109458513(HDAC5)
PALE: 102884149(HDAC4) 102887744(HDAC5)
LAV: 100657549 100676072(HDAC4) 111751790(HDAC5)
MDO: 100019600(HDAC5)
SHR: 100923523 100930442(HDAC5)
OAA: 100080036(HDAC4)
GGA: 374207(HDAC4)
MGP: 100546504(HDAC4)
CJO: 107316388(HDAC4) 107325068(HDAC5)
APLA: 101793488(HDAC4)
ACYG: 106034511(HDAC4)
TGU: 100222021(HDAC4)
GFR: 102033646(HDAC5) 102037013(HDAC4)
FAB: 101816758(HDAC4)
PHI: 102104006(HDAC5) 102111789(HDAC4)
PMAJ: 107199064(HDAC5) 107207466(HDAC4)
CCW: 104694575(HDAC4)
FPG: 101914331(HDAC5) 101918053(HDAC4)
FCH: 102049582(HDAC4) 102056554(HDAC5)
CLV: 102092668(HDAC4) 102098934(HDAC5)
EGZ: 104122546(HDAC4)
AAM: 106489325(HDAC4)
ASN: 102379663(HDAC4) 102380966(HDAC5)
AMJ: 102568102(HDAC5) 102576843(HDAC4)
PSS: 102446580(HDAC5) 102461734(HDAC4)
CMY: 102936440(HDAC5) 102945553(HDAC4)
CPIC: 101937368(HDAC5) 101950797(HDAC4)
ACS: 100567046(hdac4) 100567204(hdac5)
PVT: 110079145(HDAC5) 110081897(HDAC4)
PBI: 103054815(HDAC5) 103061054(HDAC4)
GJA: 107120120 107120475(HDAC5)
XLA: 108700835(hdac5.L) 108701411(hdac4.L) 108702540(hdac5.S) 108703026(hdac4.S)
XTR: 100487783(hdac5) 100489340(hdac4)
NPR: 108784023(HDAC5) 108793627(HDAC4)
DRE: 557486(hdac5) 568877(hdac4)
IPU: 108256906(hdac5) 108266195(hdac4)
AMEX: 103029534(hdac4) 103035634(hdac5) 103041643
TRU: 101065510(hdac5) 101072308(hdac4) 101077704
MZE: 101464986 101478760(hdac5) 101483031(hdac4)
OLA: 101157017 101168045(hdac5) 101175137(hdac4)
NFU: 107380874 107389385(hdac4) 107391815(hdac5)
CSEM: 103389529(hdac4) 103392446 103393597(hdac5)
BPEC: 110153179(hdac4) 110162386(hdac5)
ELS: 105013409(hdac5) 105016191(hdac4) 105023749
LCM: 102357880(HDAC4) 102360989(HDAC5)
CMK: 103183779(hdac5) 103186688(hdac4)
CIN: 100181525
SPU: 593178
APLC: 110977423
SKO: 102803546
DME: Dmel_CG1770(HDAC4)
DSI: Dsimw501_GD15892(Dsim_GD15892)
MDE: 101889299
AAG: 5574971
AME: 408331(HDAC4)
BIM: 100740538
BTER: 100645293
AEC: 105147447
ACEP: 105622622
PBAR: 105426239
HST: 105191048
CFO: 105250972
LHU: 105673647
PGC: 109863670
NVI: 100122308
TCA: 655770
DPA: 109534750
NVL: 108558701
PMAC: 106710379
PRAP: 110997140
PXY: 105381867
API: 100167876
DNX: 107166535
ZNE: 110832859
FCD: 110847836
DPX: DAPPUDRAFT_442965(HDA4)
TUT: 107361111
CEL: CELE_C10E2.3(hda-4)
CBR: CBG16328(Cbr-hda-4)
BMY: Bm1_04175
TSP: Tsp_04010
CRG: 105342879
MYI: 110450026
OBI: 106877934
SHX: MS3_03702
EPA: 110254626
HMG: 100215123
AQU: 100637903
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Wang AH, Bertos NR, Vezmar M, Pelletier N, Crosato M, Heng HH, Th'ng J, Han J, Yang XJ
  Title
HDAC4, a human histone deacetylase related to yeast HDA1, is a transcriptional corepressor.
  Journal
Mol Cell Biol 19:7816-27 (1999)
DOI:10.1128/MCB.19.11.7816
  Sequence
[hsa:9759]
Reference
  Authors
Grozinger CM, Hassig CA, Schreiber SL
  Title
Three proteins define a class of human histone deacetylases related to yeast Hda1p.
  Journal
Proc Natl Acad Sci U S A 96:4868-73 (1999)
DOI:10.1073/pnas.96.9.4868
  Sequence
[hsa:9759 10014]
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