KEGG   ORTHOLOGY: K11430Help
Entry
K11430                      KO                                     

Name
EZH2
Definition
histone-lysine N-methyltransferase EZH2 [EC:2.1.1.43]
Pathway
ko00310  Lysine degradation
ko05206  MicroRNAs in cancer
Disease
H01613  Follicular lymphoma
H01751  Weaver syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Amino acid metabolism
   00310 Lysine degradation
    K11430  EZH2; histone-lysine N-methyltransferase EZH2
 Human Diseases
  Cancers
   05206 MicroRNAs in cancer
    K11430  EZH2; histone-lysine N-methyltransferase EZH2
Enzymes [BR:ko01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.43  histone-lysine N-methyltransferase
     K11430  EZH2; histone-lysine N-methyltransferase EZH2
Chromosome and associated proteins [BR:ko03036]
 Eukaryotic Type
  Histone modification proteins
   HMTs (histone methyltransferases)
    HKMTs (histone lysine methyltransferases)
     K11430  EZH2; histone-lysine N-methyltransferase EZH2
   Polycomb group proteins
    PRC2-EZH2 complex
     K11430  EZH2; histone-lysine N-methyltransferase EZH2
BRITE hierarchy
Other DBs
RN: R03875 R03938 R04866 R04867
GO: 0018024
Genes
HSA: 2146(EZH2)
PTR: 745437(EZH2)
PPS: 100971244(EZH2)
GGO: 101147968(EZH2)
PON: 100447447(EZH2)
NLE: 100580962(EZH2)
MCC: 709075(EZH2)
MCF: 102146280(EZH2)
CSAB: 103227182(EZH2)
RRO: 104667012(EZH2)
RBB: 108522307(EZH2)
CJC: 100394758(EZH2)
SBQ: 101051611(EZH2)
MMU: 14056(Ezh2)
RNO: 312299(Ezh2)
CGE: 100758055(Ezh2)
NGI: 103731383(Ezh2)
HGL: 101702710(Ezh2)
CCAN: 109695508(Ezh2)
OCU: 100345157(EZH2)
TUP: 102495627(EZH2)
CFA: 475511(EZH2)
AML: 100466177(EZH2)
UMR: 103668955(EZH2)
ORO: 101369941(EZH2)
FCA: 101087309(EZH2)
PTG: 102956220(EZH2)
AJU: 106981407(EZH2)
BTA: 509106(EZH2)
BOM: 102287858(EZH2)
BIU: 109557756(EZH2)
PHD: 102335328(EZH2)
CHX: 102190101(EZH2)
OAS: 101120745(EZH2)
SSC: 100625497(EZH2)
CFR: 102515793(EZH2)
CDK: 105085196(EZH2)
BACU: 103011369(EZH2)
LVE: 103069623(EZH2)
OOR: 101280796(EZH2)
ECB: 100051290(EZH2)
EPZ: 103553703(EZH2)
EAI: 106842131(EZH2)
MYB: 102246299(EZH2)
MYD: 102768989(EZH2)
HAI: 109395452(EZH2)
RSS: 109451287(EZH2)
PALE: 102886689(EZH2)
LAV: 100664312(EZH2)
TMU: 101359039
MDO: 100013390(EZH2)
SHR: 100926678(EZH2)
OAA: 100073485(EZH2)
GGA: 420784(EZH2)
MGP: 100540374(EZH2)
CJO: 107309835(EZH2)
APLA: 101793453(EZH2)
ACYG: 106048735(EZH2)
TGU: 100226728(EZH2)
GFR: 102038673(EZH2)
FAB: 101809240(EZH2)
PHI: 102099930(EZH2)
PMAJ: 107200653(EZH2)
CCW: 104688925(EZH2)
FPG: 101911332(EZH2)
FCH: 102055584(EZH2)
CLV: 102093761(EZH2)
EGZ: 104125781(EZH2)
AAM: 106495267(EZH2)
ASN: 102372569(EZH2)
AMJ: 102562122(EZH2)
PSS: 102453330(EZH2)
CMY: 102932650(EZH2)
CPIC: 101937752(EZH2)
ACS: 100564989(ezh2)
PVT: 110088673(EZH2)
PBI: 103051581(EZH2)
GJA: 107119624(EZH2)
XLA: 100381148(ezh2.S) 399174(ezh2.L)
XTR: 550047(ezh2)
NPR: 108794364(EZH2)
DRE: 768133(ezh2)
SANH: 107686697(ezh2) 107695380
IPU: 108256455(ezh2)
AMEX: 103027230(ezh2)
TRU: 101068728(ezh2)
LCO: 104933871(ezh2)
NCC: 104940789(ezh2)
MZE: 101464777 112429845(ezh2)
OLA: 100125823(ezh2)
XMA: 102218572(ezh2)
PRET: 103457011(ezh2)
NFU: 107383138(ezh2)
CSEM: 103377188(ezh2)
LCF: 108884998(ezh2)
HCQ: 109521815(ezh2)
BPEC: 110158320(ezh2)
SASA: 106578387(ezh2) 106590561
ELS: 105022040(ezh2)
SFM: 108919665(ezh2) 108935505
CMK: 103187005(ezh2)
CIN: 100177449
APLC: 110990448
DME: Dmel_CG6502(E(z))
DSI: Dsimw501_GD12857(Dsim_GD12857)
MDE: 101887292
AAG: 5577466
AME: 552235(E(z))
BIM: 100747000
BTER: 100647736
SOC: 105197183
AEC: 105143480
ACEP: 105617407
PBAR: 105425935
CFO: 105250747
LHU: 105670949
PGC: 109855910
NVI: 100113526(E(z))
TCA: 659759
DPA: 109536169
NVL: 108560889
BMOR: 101739540 101745450(E(Z))
PMAC: 106718913
PRAP: 110995414
API: 100168406
DNX: 107161946
ZNE: 110841374
CEL: CELE_R06A4.7(mes-2)
CBR: CBG11099(Cbr-mes-2)
BMY: Bm1_55060
TSP: Tsp_01566
CRG: 105330640
MYI: 110442389
OBI: 106874217
LAK: 106181368
EPA: 110249650
HMG: 100201207
AQU: 109587656
ATH: AT1G02580(MEA) AT2G23380(CLF) AT4G02020(SWN)
LJA: Lj0g3v0213049.1(Lj0g3v0213049.1) Lj2g3v1890940.1(Lj2g3v1890940.1) Lj2g3v1890940.2(Lj2g3v1890940.2) Lj5g3v1598420.1(Lj5g3v1598420.1) Lj5g3v1598420.2(Lj5g3v1598420.2) Lj5g3v1598420.3(Lj5g3v1598420.3) Lj5g3v1598420.4(Lj5g3v1598420.4)
SLY: 100134891(EZ1) 100134892(EZ2) 101267964
DOSA: Os03t0307800-01(Os03g0307800) Os06t0275500-01(Os06g0275500)
ATS: 109742834(LOC109742834) 109781663(LOC109781663) 109781665(LOC109781665)
ZMA: 541954(mez1) 541955(mez3) 542659(mez2)
PPP: 112274954
MNG: MNEG_1960
MBE: MBM_04736
PNO: SNOG_00928 SNOG_16259(SNOG_16258)
PTE: PTT_08614
ZTR: MYCGRDRAFT_71291(SDG2401)
LBC: LACBIDRAFT_312288(SDG16204)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Margueron R, Li G, Sarma K, Blais A, Zavadil J, Woodcock CL, Dynlacht BD, Reinberg D
  Title
Ezh1 and Ezh2 maintain repressive chromatin through different mechanisms.
  Journal
Mol Cell 32:503-18 (2008)
DOI:10.1016/j.molcel.2008.11.004
  Sequence
[hsa:2146]
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