KEGG   ORTHOLOGY: K11832Help
Entry
K11832                      KO                                     

Name
USP1
Definition
ubiquitin carboxyl-terminal hydrolase 1 [EC:3.4.19.12]
Pathway
ko03460  Fanconi anemia pathway
Brite
KEGG Orthology (KO) [BR:ko00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03460 Fanconi anemia pathway
    K11832  USP1; ubiquitin carboxyl-terminal hydrolase 1
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors
    K11832  USP1; ubiquitin carboxyl-terminal hydrolase 1
  09182 Protein families: genetic information processing
   04121 Ubiquitin system
    K11832  USP1; ubiquitin carboxyl-terminal hydrolase 1
   03400 DNA repair and recombination proteins
    K11832  USP1; ubiquitin carboxyl-terminal hydrolase 1
Enzymes [BR:ko01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.19  Omega peptidases
    3.4.19.12  ubiquitinyl hydrolase 1
     K11832  USP1; ubiquitin carboxyl-terminal hydrolase 1
Peptidases and inhibitors [BR:ko01002]
 Cysteine peptidases
  Family C19: ubiquitin-specific protease family
   K11832  USP1; ubiquitin carboxyl-terminal hydrolase 1
Ubiquitin system [BR:ko04121]
 Deubiquitinating enzyme (DUB)
  Ubiquitin-specific proteases (UBPs)
   UBP/USP
    K11832  USP1; ubiquitin carboxyl-terminal hydrolase 1
DNA repair and recombination proteins [BR:ko03400]
 Eukaryotic type
  DSBR (double strand breaks repair)
   FA (Fanconi anemia) pathway
    Other FA pathway factors
     K11832  USP1; ubiquitin carboxyl-terminal hydrolase 1
BRITE hierarchy
Other DBs
GO: 0004843
Genes
HSA: 7398(USP1)
PTR: 456901(USP1)
PPS: 100982030(USP1)
GGO: 101124390(USP1)
PON: 100443075(USP1)
NLE: 100593568(USP1)
MCC: 695157(USP1)
MCF: 102140426(USP1)
CSAB: 103224705(USP1)
RRO: 104668056(USP1)
RBB: 108532907(USP1)
CJC: 100411303(USP1)
SBQ: 101037206(USP1)
MMU: 230484(Usp1)
MCAL: 110292834(Usp1)
MPAH: 110323098(Usp1)
RNO: 313387(Usp1)
CGE: 100754655(Usp1)
NGI: 103745294(Usp1)
HGL: 101716794(Usp1)
CCAN: 109686141(Usp1)
OCU: 100358366(USP1)
TUP: 102496372(USP1)
CFA: 479549(USP1)
VVP: 112926075(USP1)
AML: 100473360(USP1)
UMR: 103663070(USP1)
UAH: 113254591(USP1)
ORO: 101365740(USP1)
ELK: 111143364
FCA: 101080903(USP1)
PTG: 102965527(USP1)
PPAD: 109266754(USP1)
AJU: 106975049(USP1)
BTA: 516328(USP1)
BOM: 102275237(USP1)
BIU: 109556215(USP1)
BBUB: 102393164(USP1)
CHX: 102187448(USP1)
OAS: 101107236(USP1)
SSC: 100523071(USP1)
CFR: 102522295(USP1)
CDK: 105096281(USP1)
BACU: 103008560(USP1)
LVE: 103085454(USP1)
OOR: 101277953(USP1)
DLE: 111178475(USP1) 111178911
ECB: 100070397(USP1)
EPZ: 103557297(USP1)
EAI: 106839757(USP1)
MYB: 102252055(USP1)
MYD: 102751651(USP1)
MNA: 107533772(USP1)
HAI: 109389715(USP1)
DRO: 112309306(USP1)
PALE: 102898461(USP1)
RAY: 107508512(USP1)
MJV: 108408077(USP1)
LAV: 100668820(USP1)
TMU: 101350476
MDO: 100031700(USP1)
SHR: 100919331(USP1)
PCW: 110212898(USP1)
OAA: 103165248(USP1)
GGA: 424685(USP1)
MGP: 100550349(USP1)
CJO: 107317711(USP1)
NMEL: 110402765(USP1)
APLA: 101791738(USP1)
ACYG: 106032976(USP1)
TGU: 100218324(USP1)
LSR: 110477240(USP1)
SCAN: 103815064(USP1)
GFR: 102033112(USP1)
FAB: 101819959(USP1)
PHI: 102114174(USP1)
PMAJ: 107208143(USP1)
CCAE: 111932978(USP1)
CCW: 104695142(USP1)
ETL: 114057164(USP1)
FPG: 101920556(USP1)
FCH: 102058157(USP1)
CLV: 102096717(USP1)
EGZ: 104123936(USP1)
NNI: 104009255(USP1)
ACUN: 113482797(USP1)
PADL: 103913330(USP1)
AAM: 106490530(USP1)
ASN: 102384046(USP1)
AMJ: 102558353(USP1)
PSS: 102446936(USP1)
CMY: 102935301(USP1)
CPIC: 101943153(USP1)
ACS: 100560711(usp1)
PVT: 110086663(USP1)
PBI: 103053739(USP1)
PMUR: 107287082(USP1)
TSR: 106542333(USP1)
PMUA: 114598905(USP1)
GJA: 107113835(USP1)
XLA: 398530(usp1-b) 447465(usp1.S)
XTR: 780036(usp1)
NPR: 108784907(USP1)
DRE: 322007(usp1)
SRX: 107717136(usp1) 107731620
SANH: 107692387(usp1)
SGH: 107556553(usp1) 107591200
IPU: 108271857(usp1)
PHYP: 113528206(usp1)
AMEX: 103031820(usp1)
EEE: 113587817(usp1)
TRU: 101070932(usp1)
LCO: 104919030(usp1)
NCC: 104962141(usp1)
MZE: 101483960(usp1)
ONL: 100692281(usp1)
OLA: 101167111(usp1)
XMA: 102223254(usp1)
XCO: 114151567(usp1)
PRET: 103463056(usp1)
CVG: 107097924(usp1)
NFU: 107392927(usp1)
KMR: 108238474(usp1)
ALIM: 106521633(usp1)
AOCE: 111575417(usp1)
CSEM: 103396022(usp1)
POV: 109636658(usp1)
LCF: 108887066 108893032(usp1)
SDU: 111238180(usp1)
SLAL: 111645371(usp1)
HCQ: 109530541(usp1)
BPEC: 110160059(usp1)
MALB: 109961716(usp1)
SASA: 106560492(usp1)
OTW: 112251370(usp1)
ELS: 105011905(usp1)
SFM: 108935346(usp1)
PKI: 111834809(usp1)
LCM: 102364423(USP1)
CMK: 103188830(usp1)
RTP: 109914306(usp1)
SPU: 576951
APLC: 110980306
SKO: 100366443
DME: Dmel_CG15817(Usp1)
DER: 6554872
DSI: Dsimw501_GD21429(Dsim_GD21429)
DSR: 110186855
DPE: 6595231
DMN: 108155268
DWI: 6649795
DAZ: 108615989
DNV: 108659360
DHE: 111595229
MDE: 101901131
LCQ: 111687911
AAG: 5574653
AME: 409389
BIM: 100744437
BTER: 100651944
CCAL: 108628532
OBB: 114879414
SOC: 105197507
MPHA: 105836375
AEC: 105154676
ACEP: 105626913
PBAR: 105424763
VEM: 105569872
HST: 105185496
DQU: 106745362
CFO: 105252110
LHU: 105678972
PGC: 109852754
OBO: 105283367
PCF: 106785234
NVI: 100216456
CSOL: 105361769
MDL: 103579689
TCA: 657237
NVL: 108567481
BMOR: 101736682
BMAN: 114245259
PMAC: 106719647
PRAP: 110995319
HAW: 110383949
TNL: 113500421
API: 100162534
DNX: 107167146
AGS: 114128377
RMD: 113559310
BTAB: 109034693
CLEC: 106669715
ZNE: 110829613
PVM: 113816604
PCAN: 112556047
CRG: 105333421
MYI: 110463580
OBI: 106878488
LAK: 106150593
EPA: 110241255
ADF: 107341483
AMIL: 114959447
PDAM: 113671447
SPIS: 111324788
DGT: 114529018
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Nijman SM, Huang TT, Dirac AM, Brummelkamp TR, Kerkhoven RM, D'Andrea AD, Bernards R
  Title
The deubiquitinating enzyme USP1 regulates the Fanconi anemia pathway.
  Journal
Mol Cell 17:331-9 (2005)
DOI:10.1016/j.molcel.2005.01.008
  Sequence
[hsa:7398]
Reference
  Authors
Murai J, Yang K, Dejsuphong D, Hirota K, Takeda S, D'Andrea AD
  Title
The USP1/UAF1 Complex Promotes Double-Strand Break Repair through Homologous Recombination.
  Journal
Mol Cell Biol 31:2462-9 (2011)
DOI:10.1128/MCB.05058-11
  Sequence
[gga:424685]
LinkDB All DBs

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