KEGG   ORTHOLOGY: K11838Help
Entry
K11838                      KO                                     

Name
USP7, UBP15
Definition
ubiquitin carboxyl-terminal hydrolase 7 [EC:3.4.19.12]
Pathway
ko04068  FoxO signaling pathway
ko05169  Epstein-Barr virus infection
ko05203  Viral carcinogenesis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04068 FoxO signaling pathway
    K11838  USP7, UBP15; ubiquitin carboxyl-terminal hydrolase 7
 09160 Human Diseases
  09161 Cancer: overview
   05203 Viral carcinogenesis
    K11838  USP7, UBP15; ubiquitin carboxyl-terminal hydrolase 7
  09172 Infectious disease: viral
   05169 Epstein-Barr virus infection
    K11838  USP7, UBP15; ubiquitin carboxyl-terminal hydrolase 7
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors
    K11838  USP7, UBP15; ubiquitin carboxyl-terminal hydrolase 7
  09182 Protein families: genetic information processing
   04121 Ubiquitin system
    K11838  USP7, UBP15; ubiquitin carboxyl-terminal hydrolase 7
Enzymes [BR:ko01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.19  Omega peptidases
    3.4.19.12  ubiquitinyl hydrolase 1
     K11838  USP7, UBP15; ubiquitin carboxyl-terminal hydrolase 7
Peptidases and inhibitors [BR:ko01002]
 Cysteine peptidases
  Family C19: ubiquitin-specific protease family
   K11838  USP7, UBP15; ubiquitin carboxyl-terminal hydrolase 7
Ubiquitin system [BR:ko04121]
 Deubiquitinating enzyme (DUB)
  Ubiquitin-specific proteases (UBPs)
   UBP/USP
    K11838  USP7, UBP15; ubiquitin carboxyl-terminal hydrolase 7
BRITE hierarchy
Other DBs
GO: 0004843
Genes
HSA: 7874(USP7)
PTR: 453907(USP7)
PPS: 100979081(USP7)
GGO: 101152862(USP7)
PON: 100437824(USP7)
NLE: 100583734(USP7)
MCC: 714625(USP7)
MCF: 101926240(USP7)
CSAB: 103228044(USP7)
RRO: 104678381(USP7)
RBB: 108531140(USP7)
CJC: 100410859(USP7)
SBQ: 101038759(USP7)
MMU: 252870(Usp7)
MCAL: 110312081(Usp7)
MPAH: 110314512 110329340(Usp7)
RNO: 360471(Usp7)
MUN: 110553202(Usp7)
CGE: 100769056(Usp7)
NGI: 103731591(Usp7)
HGL: 101715332(Usp7)
CCAN: 109695879(Usp7)
OCU: 100358775(USP7)
TUP: 102472042 102486409(USP7)
CFA: 479854(USP7)
VVP: 112923306(USP7)
AML: 100468835(USP7)
UMR: 103668586(USP7)
UAH: 113270814(USP7)
ORO: 101379726(USP7)
ELK: 111155980
FCA: 101088134(USP7)
PTG: 102950246(USP7)
PPAD: 109278301(USP7)
AJU: 106971787(USP7)
BTA: 514813(USP7)
BOM: 102264982(USP7)
BIU: 109578469(USP7)
BBUB: 102408990(USP7)
CHX: 102188997(USP7)
OAS: 101106735(USP7)
SSC: 100190899(USP7)
CFR: 102504036(USP7)
CDK: 105098596(USP7)
BACU: 103006618(USP7)
LVE: 103075423(USP7)
OOR: 101271260(USP7)
DLE: 111163479(USP7)
PCAD: 102996770(USP7) 114485182
ECB: 100057484(USP7)
EPZ: 103556240(USP7)
EAI: 106836766(USP7)
MYB: 102244142(USP7)
MYD: 102765208(USP7)
MNA: 107526815(USP7)
HAI: 109395275(USP7)
PALE: 102897683(USP7)
RAY: 107515372(USP7)
MJV: 108398942(USP7)
LAV: 100665823(USP7)
TMU: 101353384
MDO: 100018496(USP7)
SHR: 100921052(USP7)
PCW: 110198581(USP7)
OAA: 100074824(USP7)
GGA: 395126(USP7)
MGP: 100549535(USP7) 104913369
CJO: 107320832(USP7)
NMEL: 110405717(USP7)
APLA: 101789752(USP7)
ACYG: 106041212(USP7)
TGU: 100221531(USP7)
LSR: 110475648(USP7)
SCAN: 103817734(USP7)
GFR: 102042457(USP7)
FAB: 101807896(USP7)
PHI: 102113371(USP7)
PMAJ: 107211224(USP7)
CCAE: 111922427 111935927(USP7)
CCW: 104684700(USP7)
ETL: 114058633(USP7)
FPG: 101912182(USP7)
FCH: 102048670(USP7)
CLV: 102097347(USP7)
EGZ: 104127642(USP7)
NNI: 104023443(USP7)
ACUN: 113485557(USP7)
PADL: 103917559(USP7)
AAM: 106482615(USP7)
ASN: 102381850(USP7)
AMJ: 102576037(USP7)
PSS: 102452147(USP7) 102463945
CMY: 102935657(USP7)
CPIC: 101934793(USP7)
ACS: 100567733(usp7)
PVT: 110090438(USP7)
PBI: 103061755(USP7)
PMUR: 107296635(USP7)
PMUA: 114584971(USP7)
GJA: 107125671(USP7)
XLA: 100158365(usp7.S) 108701518(usp7.L)
XTR: 100124302(usp7)
NPR: 108798125(USP7)
DRE: 553758(usp7)
SANH: 107685919
IPU: 108278830(usp7)
PHYP: 113546922(usp7)
AMEX: 103024319(usp7)
EEE: 113572850(usp7)
TRU: 101078683(usp7)
LCO: 104917634(usp7)
NCC: 104965842(usp7)
MZE: 101467618(usp7) 101468977
ONL: 100709815(usp7)
OLA: 101165311(usp7)
XMA: 102227868(usp7)
XCO: 114159576(usp7)
PRET: 103468578(usp7)
CVG: 107093525(usp7)
NFU: 107376398(usp7)
KMR: 108236196(usp7)
ALIM: 106534243(usp7)
CSEM: 103393241(usp7)
POV: 109641940(usp7)
LCF: 108881085(usp7)
SDU: 111230229(usp7)
HCQ: 109512580(usp7)
BPEC: 110155738(usp7)
MALB: 109958908(usp7)
OTW: 112240744(usp7)
SALP: 112077597(usp7)
ELS: 105013471(usp7)
SFM: 108937431(usp7)
PKI: 111849192(usp7)
LCM: 102352615(USP7)
CMK: 103186075(usp7)
RTP: 109911764 109915840(usp7)
CIN: 100177157
SPU: 575057
APLC: 110986042
DME: Dmel_CG1490(Usp7)
DER: 6551297
DSI: Dsimw501_GD15945(Dsim_GD15945)
DSR: 110179674
DPE: 6598275
DMN: 108153574
DWI: 6649007
DAZ: 108619214
DNV: 108656914
DHE: 111596802
MDE: 101896805
LCQ: 111681273
AAG: 23687579
AALB: 109420687
AME: 409332
BIM: 100749463
BTER: 100650609
OBB: 114881511
SOC: 105196644
MPHA: 105829404
AEC: 105148460
ACEP: 105627448
PBAR: 105430919
VEM: 105565626
HST: 105183281
DQU: 106743254
CFO: 105258317
LHU: 105676891
OBO: 105279525
PCF: 106793462
NVI: 100498674(Usp7)
CSOL: 105365856
TCA: 663824(USP7)
DPA: 109538246
ATD: 109598246
NVL: 108556314
API: 100158926
AGS: 114121230
RMD: 113548661
BTAB: 109041804
CLEC: 106669810
ZNE: 110827606
FCD: 110844028
PVM: 113820154
TUT: 107362577
DPTE: 113797211
PTEP: 107444438
CEL: CELE_H19N07.2(math-33)
CBR: CBG23105(Cbr-math-33)
BMY: Bm1_38125
TSP: Tsp_02424
PCAN: 112565816
CRG: 105348986
OBI: 106876495
LAK: 106157345
SHX: MS3_04405
EPA: 110239977
ADF: 107354120
AMIL: 114973790
PDAM: 113680326
SPIS: 111329693
DGT: 114519248
HMG: 100201254(usp7) 100215841
AQU: 100638474
ATH: AT3G11910(UBP13) AT5G06600(UBP12)
LJA: Lj0g3v0261909.1(Lj0g3v0261909.1) Lj0g3v0261909.2(Lj0g3v0261909.2) Lj0g3v0261909.3(Lj0g3v0261909.3) Lj2g3v2905020.1(Lj2g3v2905020.1) Lj5g3v1697410.1(Lj5g3v1697410.1) Lj6g3v1038860.1(Lj6g3v1038860.1) Lj6g3v1055600.1(Lj6g3v1055600.1)
DOSA: Os01t0771400-00(Os01g0771400) Os07t0163800-01(Os07g0163800) Os11t0573000-01(Os11g0573000) Os12t0489100-01(Os12g0489100)
ATS: 109741570(LOC109741570) 109747186(LOC109747186) 109770527(LOC109770527) 109779701(LOC109779701)
ATR: 18421576
APRO: F751_5126
SCE: YMR304W(UBP15)
ERC: Ecym_5671
KMX: KLMA_80201(UBP15)
NCS: NCAS_0D02390(NCAS0D02390)
NDI: NDAI_0I02530(NDAI0I02530)
TPF: TPHA_0L02290(TPHA0L02290)
TBL: TBLA_0C07020(TBLA0C07020)
TDL: TDEL_0G00410(TDEL0G00410)
KAF: KAFR_0I02600(KAFR0I02600)
PIC: PICST_90001(UBP15)
CAL: CAALFM_C210050WA(CaO19.1777)
SLB: AWJ20_1658(UBP15)
NCR: NCU03797
NTE: NEUTE1DRAFT37552(NEUTE1DRAFT_37552)
MGR: MGG_07468
SSCK: SPSK_02164
MAW: MAC_00470
MAJ: MAA_07334
CMT: CCM_09140
MBE: MBM_08527
ANG: ANI_1_684084(An09g05480)
PBL: PAAG_04327 PAAG_11336(PAAG_01673)
PTE: PTT_18104
SPO: SPBC713.02c(ubp15) SPCC188.08c(ubp5)
CNE: CNH02890
CNB: CNBL2960
ABP: AGABI1DRAFT53175(AGABI1DRAFT_53175)
ABV: AGABI2DRAFT199569(AGABI2DRAFT_199569)
MGL: MGL_3966
MRT: MRET_2815
DDI: DDB_G0276443(usp7)
DFA: DFA_03676(usp7)
PYO: PY17X_0212000(PY01440)
PCB: PCHAS_020900(PC001064.02.0)
TAN: TA04875
TPV: TP03_0494
BBO: BBOV_IV001730(21.m03027)
CPV: cgd8_1530
SMIN: v1.2.002654.t1(symbB.v1.2.002654.t1) v1.2.002654.t3(symbB.v1.2.002654.t3) v1.2.020858.t1(symbB.v1.2.020858.t1) v1.2.023344.t1(symbB.v1.2.023344.t1) v1.2.040915.t1(symbB.v1.2.040915.t1)
SPAR: SPRG_07869
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Felle M, Joppien S, Nemeth A, Diermeier S, Thalhammer V, Dobner T, Kremmer E, Kappler R, Langst G
  Title
The USP7/Dnmt1 complex stimulates the DNA methylation activity of Dnmt1 and regulates the stability of UHRF1.
  Journal
Nucleic Acids Res 39:8355-65 (2011)
DOI:10.1093/nar/gkr528
  Sequence
[hsa:7874]
Reference
PMID:9034339
  Authors
Everett RD, Meredith M, Orr A, Cross A, Kathoria M, Parkinson J
  Title
A novel ubiquitin-specific protease is dynamically associated with the PML nuclear domain and binds to a herpesvirus regulatory protein.
  Journal
EMBO J 16:566-77 (1997)
DOI:10.1093/emboj/16.3.566
  Sequence
[hsa:7874]
LinkDB All DBs

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