KEGG   ORTHOLOGY: K13296Help
Entry
K13296                      KO                                     

Name
PDE3B
Definition
cGMP-inhibited 3',5'-cyclic phosphodiesterase B [EC:3.1.4.17]
Pathway
ko00230  Purine metabolism
ko01100  Metabolic pathways
ko04022  cGMP-PKG signaling pathway
ko04024  cAMP signaling pathway
ko04371  Apelin signaling pathway
ko04910  Insulin signaling pathway
ko04914  Progesterone-mediated oocyte maturation
ko04922  Glucagon signaling pathway
ko04923  Regulation of lipolysis in adipocytes
ko04924  Renin secretion
ko05032  Morphine addiction
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    K13296  PDE3B; cGMP-inhibited 3',5'-cyclic phosphodiesterase B
 09130 Environmental Information Processing
  09132 Signal transduction
   04371 Apelin signaling pathway
    K13296  PDE3B; cGMP-inhibited 3',5'-cyclic phosphodiesterase B
   04024 cAMP signaling pathway
    K13296  PDE3B; cGMP-inhibited 3',5'-cyclic phosphodiesterase B
   04022 cGMP-PKG signaling pathway
    K13296  PDE3B; cGMP-inhibited 3',5'-cyclic phosphodiesterase B
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    K13296  PDE3B; cGMP-inhibited 3',5'-cyclic phosphodiesterase B
   04922 Glucagon signaling pathway
    K13296  PDE3B; cGMP-inhibited 3',5'-cyclic phosphodiesterase B
   04923 Regulation of lipolysis in adipocytes
    K13296  PDE3B; cGMP-inhibited 3',5'-cyclic phosphodiesterase B
   04914 Progesterone-mediated oocyte maturation
    K13296  PDE3B; cGMP-inhibited 3',5'-cyclic phosphodiesterase B
   04924 Renin secretion
    K13296  PDE3B; cGMP-inhibited 3',5'-cyclic phosphodiesterase B
 09160 Human Diseases
  09165 Substance dependence
   05032 Morphine addiction
    K13296  PDE3B; cGMP-inhibited 3',5'-cyclic phosphodiesterase B
Enzymes [BR:ko01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.17  3',5'-cyclic-nucleotide phosphodiesterase
     K13296  PDE3B; cGMP-inhibited 3',5'-cyclic phosphodiesterase B
BRITE hierarchy
Other DBs
RN: R00191 R01234
GO: 0004119
Genes
HSA: 5140(PDE3B)
PTR: 451041(PDE3B)
PPS: 100972602(PDE3B)
GGO: 101149202(PDE3B)
PON: 100460789(PDE3B)
NLE: 100600080(PDE3B)
MCC: 698954(PDE3B)
MCF: 102139399(PDE3B)
CSAB: 103239798(PDE3B)
RRO: 104681940(PDE3B)
RBB: 108535503(PDE3B)
CJC: 100393923(PDE3B)
SBQ: 101046670(PDE3B)
MMU: 18576(Pde3b)
MCAL: 110297913(Pde3b)
MPAH: 110320990(Pde3b)
RNO: 29516(Pde3b)
MUN: 110549429(Pde3b)
CGE: 100775064(Pde3b)
NGI: 103750457(Pde3b)
HGL: 101724440(Pde3b)
CCAN: 109695445(Pde3b)
OCU: 100352820(PDE3B)
TUP: 102495517(PDE3B)
CFA: 611730(PDE3B)
VVP: 112926998(PDE3B)
AML: 100482771(PDE3B)
UMR: 103682384(PDE3B)
UAH: 113246251(PDE3B)
ORO: 101371957(PDE3B)
FCA: 101094877(PDE3B)
PTG: 102966458(PDE3B)
AJU: 106989114(PDE3B)
BTA: 533323(PDE3B)
BOM: 102284270(PDE3B) 102285991
BIU: 109569608(PDE3B)
BBUB: 102394766(PDE3B)
PHD: 102341685(PDE3B)
CHX: 102190893(PDE3B)
OAS: 101121291(PDE3B)
SSC: 100516060(PDE3B)
CFR: 102503956(PDE3B)
CDK: 105086706(PDE3B)
BACU: 103008332(PDE3B)
LVE: 103068542(PDE3B)
OOR: 101270317(PDE3B)
DLE: 111165285(PDE3B)
PCAD: 102986230(PDE3B)
ECB: 100071615(PDE3B)
EPZ: 103557936(PDE3B)
EAI: 106830429 106833050(PDE3B)
MYB: 102259206(PDE3B)
MYD: 102765733(PDE3B)
MNA: 107546709(PDE3B)
HAI: 109388277(PDE3B)
RSS: 109459726(PDE3B)
DRO: 112303291(PDE3B)
PALE: 102894289(PDE3B)
RAY: 107519402(PDE3B)
LAV: 100660871(PDE3B)
TMU: 101355565
MDO: 100029160(PDE3B)
SHR: 100934547(PDE3B)
PCW: 110220994(PDE3B)
OAA: 100088979(PDE3B)
GGA: 423064(PDE3B)
MGP: 100547369(PDE3B)
CJO: 107314630(PDE3B)
NMEL: 110401246(PDE3B)
APLA: 101798259(PDE3B)
ACYG: 106040925(PDE3B)
TGU: 100231533(PDE3B)
LSR: 110468046(PDE3B)
SCAN: 103827031(PDE3B)
GFR: 102035875(PDE3B)
FAB: 101814223(PDE3B)
PHI: 102110415(PDE3B)
PMAJ: 107205883(PDE3B)
CCW: 104687817(PDE3B)
ETL: 114060399(PDE3B)
FPG: 101919766(PDE3B)
FCH: 102048500(PDE3B)
CLV: 102098034(PDE3B)
EGZ: 104123195(PDE3B)
NNI: 104010948(PDE3B)
ACUN: 113480962(PDE3B)
PADL: 103923803(PDE3B)
AAM: 106497111(PDE3B)
ASN: 102368588(PDE3B)
AMJ: 102562481(PDE3B)
PSS: 102462190(PDE3B)
CMY: 102938238(PDE3B)
CPIC: 101941595(PDE3B) 101946638
ACS: 100556429(pde3b)
PVT: 110083180(PDE3B)
PBI: 103054757
PMUR: 107295022(PDE3B)
GJA: 107120115(PDE3B)
XLA: 108715307 496104(pde3b.L)
XTR: 100487373(pde3b)
DRE: 563432(si:ch211-79e4.4)
SGH: 107585943 107593359(pde3b)
IPU: 108271336(pde3b)
PHYP: 113536443(pde3b)
AMEX: 103038322(pde3b)
EEE: 113575781(pde3b)
TRU: 101071965(pde3b)
LCO: 104919129(pde3b)
NCC: 104964399(pde3b)
MZE: 101469697(pde3b)
OLA: 101164632(pde3b)
XMA: 102237705(pde3b)
XCO: 114143385(pde3b)
PRET: 103462442(pde3b)
NFU: 107381568(pde3b)
KMR: 108251643(pde3b)
AOCE: 111563275(pde3b)
CSEM: 103379285(pde3b)
POV: 109636766(pde3b)
LCF: 108888822(pde3b)
SDU: 111236552(pde3b)
HCQ: 109525876(pde3b)
BPEC: 110172817(pde3b)
MALB: 109963611(pde3b)
SALP: 111969490
ELS: 105022265(pde3b)
SFM: 108934551 108939323(pde3b)
LCM: 102357842(PDE3B)
CMK: 103174909(pde3b)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Kitamura T, Kitamura Y, Kuroda S, Hino Y, Ando M, Kotani K, Konishi H, Matsuzaki H, Kikkawa U, Ogawa W, Kasuga M
  Title
Insulin-induced phosphorylation and activation of cyclic nucleotide phosphodiesterase 3B by the serine-threonine kinase Akt.
  Journal
Mol Cell Biol 19:6286-96 (1999)
DOI:10.1128/MCB.19.9.6286
  Sequence
[mmu:18576]
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