KEGG   ORTHOLOGY: K14959Help
Entry
K14959                      KO                                     

Name
MLL4
Definition
histone-lysine N-methyltransferase MLL4 [EC:2.1.1.43]
Pathway
ko00310  Lysine degradation
Disease
H00831  Primary dystonia
H01613  Follicular lymphoma
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00310 Lysine degradation
    K14959  MLL4; histone-lysine N-methyltransferase MLL4
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K14959  MLL4; histone-lysine N-methyltransferase MLL4
   03036 Chromosome and associated proteins
    K14959  MLL4; histone-lysine N-methyltransferase MLL4
Enzymes [BR:ko01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.43  histone-lysine N-methyltransferase
     K14959  MLL4; histone-lysine N-methyltransferase MLL4
Transcription factors [BR:ko03000]
 Eukaryotic Type
  Zinc finger
   Cys4 Trithorax
    K14959  MLL4; histone-lysine N-methyltransferase MLL4
Chromosome and associated proteins [BR:ko03036]
 Eukaryotic Type
  Histone modification proteins
   HMTs (histone methyltransferases)
    HKMTs (histone lysine methyltransferases)
     K14959  MLL4; histone-lysine N-methyltransferase MLL4
   HMT complexes
    MLL3/MLL4 complex
     K14959  MLL4; histone-lysine N-methyltransferase MLL4
BRITE hierarchy
Other DBs
RN: R03875 R03938 R04866 R04867
GO: 0042800
Genes
HSA: 9757(KMT2B)
PTR: 455959(KMT2B)
PPS: 100979249(KMT2B)
GGO: 101139923(KMT2B)
PON: 100442005(KMT2B)
NLE: 100594433(KMT2B)
MCC: 718835(KMT2B)
MCF: 102115861(KMT2B) 107128203
CSAB: 103234531(KMT2B)
RRO: 104667085(KMT2B) 104667132
RBB: 108512323(KMT2B)
CJC: 100407541(KMT2B)
SBQ: 101034359(KMT2B) 101049466
MMU: 75410(Kmt2b)
RNO: 102550344(Kmt2b)
CGE: 100750575(Kmt2b)
NGI: 103729965(Kmt2b)
HGL: 101699273(Kmt2b)
CCAN: 109689598(Kmt2b)
OCU: 100353483(KMT2B)
TUP: 102477772(KMT2B)
CFA: 100688666(KMT2B)
AML: 100469094(KMT2B)
UMR: 103682560(KMT2B)
ORO: 101370290(KMT2B)
FCA: 101098760(KMT2B)
PTG: 102964982(KMT2B)
AJU: 106974745(KMT2B)
BTA: 785776(KMT2B)
BOM: 102269320(KMT2B)
BIU: 109572325(KMT2B)
PHD: 102321056(KMT2B)
CHX: 102172292(KMT2B)
OAS: 101104086(KMT2B)
SSC: 100520742(KMT2B)
CFR: 102520520(KMT2B)
CDK: 105088051(KMT2B)
BACU: 103015601(KMT2B)
LVE: 103073652(KMT2B)
OOR: 101276223(KMT2B)
ECB: 100059802(KMT2B)
EPZ: 103566091(KMT2B)
EAI: 106829152(KMT2B)
MYB: 102259087(KMT2B)
MYD: 102771251(KMT2B)
HAI: 109372008(KMT2B)
RSS: 109457187(KMT2B)
PALE: 102881431(KMT2B)
LAV: 100669611(KMT2B)
TMU: 101345928
MDO: 100617561(KMT2B)
SHR: 100926753 100927672(KMT2B)
PHI: 106629042
ASN: 102382195(KMT2B)
CMY: 102931937(KMT2B)
CPIC: 101950574(KMT2B)
ACS: 100556600(kmt2b)
PVT: 110089900(KMT2B)
PBI: 103058696(KMT2B)
GJA: 107108169(KMT2B) 107109138
XTR: 100144721(kmt2b)
NPR: 108799776(KMT2B)
DRE: 560856(kmt2ba) 566825(kmt2bb)
IPU: 108272954 108277672(kmt2b)
AMEX: 103022217(kmt2b) 103024771
TRU: 101064190 101073293(kmt2b)
LCO: 104927558 104932361(kmt2b)
NCC: 104960690 104961389(kmt2b)
MZE: 101467874 101481309(kmt2b)
OLA: 101157226 101174945(kmt2b)
XMA: 102222844 102229737(kmt2b)
PRET: 103472504 103478519(kmt2b)
NFU: 107372442(kmt2b) 107394636
CSEM: 103388508(kmt2b) 103394161
HCQ: 109514546 109525616(kmt2b)
BPEC: 110161138 110171497(kmt2b)
ELS: 105007527 105019114(kmt2b)
SFM: 108930328(kmt2b)
EPA: 110242030
HMG: 100210554
AQU: 100636799
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Demers C, Chaturvedi CP, Ranish JA, Juban G, Lai P, Morle F, Aebersold R, Dilworth FJ, Groudine M, Brand M
  Title
Activator-mediated recruitment of the MLL2 methyltransferase complex to the beta-globin locus.
  Journal
Mol Cell 27:573-84 (2007)
DOI:10.1016/j.molcel.2007.06.022
  Sequence
[hsa:9757]
Reference
  Authors
Cho YW, Hong T, Hong S, Guo H, Yu H, Kim D, Guszczynski T, Dressler GR, Copeland TD, Kalkum M, Ge K
  Title
PTIP associates with MLL3- and MLL4-containing histone H3 lysine 4 methyltransferase complex.
  Journal
J Biol Chem 282:20395-406 (2007)
DOI:10.1074/jbc.M701574200
  Sequence
[hsa:9757]
LinkDB All DBs

DBGET integrated database retrieval system