KEGG   ORTHOLOGY: K14963
Entry
K14963                      KO                                     

Name
WDR5, SWD3, CPS30
Definition
COMPASS component SWD3
Pathway
ko04934  Cushing syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    K14963  WDR5, SWD3, CPS30; COMPASS component SWD3
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins
    K14963  WDR5, SWD3, CPS30; COMPASS component SWD3
Chromosome and associated proteins [BR:ko03036]
 Eukaryotic type
  Histone modification proteins
   HAT complexes
    ATAC complex
     K14963  WDR5, SWD3, CPS30; COMPASS component SWD3
    NSL complex
     K14963  WDR5, SWD3, CPS30; COMPASS component SWD3
   HMT complexes
    COMPASS/SET1 complex
     K14963  WDR5, SWD3, CPS30; COMPASS component SWD3
    COMPASS/SET1 complex (yeast)
     K14963  WDR5, SWD3, CPS30; COMPASS component SWD3
    MLL-HCF complex
     K14963  WDR5, SWD3, CPS30; COMPASS component SWD3
    MLL3/MLL4 complex
     K14963  WDR5, SWD3, CPS30; COMPASS component SWD3
Genes
HSA: 11091(WDR5) 54554(WDR5B)
PTR: 460630(WDR5B) 746901(WDR5)
PPS: 100988935(WDR5) 103782718(WDR5B)
GGO: 101128389(WDR5) 101143690(WDR5B)
PON: 100174268(WDR5B) 100937108(WDR5)
NLE: 100583558(WDR5) 100605376(WDR5B)
MCC: 714703(WDR5B) 722123(WDR5)
MCF: 102133326(WDR5) 102142817(WDR5B)
CSAB: 103228188(WDR5B) 103239670(WDR5)
RRO: 104667922(WDR5B) 104669711(WDR5)
RBB: 108513196(WDR5) 108519294(WDR5B)
CJC: 100404600(WDR5B) 100407139(WDR5)
SBQ: 101044805(WDR5) 101046172(WDR5B)
MMU: 140858(Wdr5) 69544(Wdr5b)
MCAL: 110289684(Wdr5) 110311569(Wdr5b)
MPAH: 110318087(Wdr5) 110329721(Wdr5b)
RNO: 303907(Wdr5b) 362093(Wdr5)
MUN: 110547225(Wdr5b) 110548924(Wdr5)
CGE: 100767658(Wdr5b) 100768958(Wdr5)
NGI: 103741975(Wdr5b) 103742822(Wdr5)
HGL: 101696645(Wdr5b) 101723351(Wdr5)
CCAN: 109689244(Wdr5b) 109695048(Wdr5)
OCU: 100358109(WDR5B)
TUP: 102475039(WDR5B) 102501799(WDR5)
CFA: 100685660(WDR5B) 608113(WDR5)
VVP: 112913493(WDR5B) 112935884(WDR5)
AML: 100477065(WDR5) 100484804(WDR5B)
UMR: 103678761(WDR5B) 103679925(WDR5)
UAH: 113252248(WDR5B) 113266583(WDR5)
ORO: 101364832(WDR5) 101384276(WDR5B)
FCA: 101082447(WDR5) 101086592(WDR5B)
PTG: 102952912(WDR5B) 102957253(WDR5)
PPAD: 109258265(WDR5) 109266477(WDR5B)
AJU: 106984103(WDR5B) 106988270(WDR5)
BTA: 100125836(WDR5) 100138335(WDR5B)
BOM: 102264764(WDR5) 102273992(WDR5B)
BIU: 109555088(WDR5B)
BBUB: 102405727(WDR5B) 102405857(WDR5)
CHX: 102177810(WDR5) 102186906(WDR5B)
OAS: 101113552(WDR5B) 101118597(WDR5)
SSC: 100156729(WDR5) 100627452(WDR5B)
CFR: 102509213(WDR5) 102520548(WDR5B)
CDK: 105090294(WDR5B) 105102806(WDR5)
BACU: 103002089(WDR5B) 103004110(WDR5)
LVE: 103071811(WDR5B) 103083572(WDR5)
OOR: 101269329(WDR5B) 101270353(WDR5)
DLE: 111171472(WDR5B) 111177067(WDR5)
PCAD: 102991102(WDR5) 102991509(WDR5B)
ECB: 100069126(WDR5) 100070656(WDR5B)
EPZ: 103548429(WDR5B) 103561602(WDR5)
EAI: 106823723(WDR5B) 106845344(WDR5)
MYB: 102258638(WDR5B) 102259721(WDR5)
MYD: 102762509(WDR5) 102767541(WDR5B)
MNA: 107524615(WDR5) 107527400(WDR5B)
HAI: 109381213(WDR5) 109388223(WDR5B)
DRO: 112306429(WDR5) 112320639(WDR5B)
PALE: 102881828(WDR5) 102887720(WDR5B)
RAY: 107502029(WDR5) 107512488(WDR5B)
MJV: 108399549(WDR5) 108407467(WDR5B)
LAV: 100671380(WDR5B) 100673925(WDR5)
SHR: 100921909(WDR5) 100930938
PCW: 110205366(WDR5)
OAA: 100074270(WDR5)
GGA: 417144(WDR5)
MGP: 100541376(WDR5)
CJO: 107321859(WDR5)
NMEL: 110406798(WDR5)
APLA: 101797619(WDR5)
ACYG: 106044131(WDR5)
TGU: 100227253(WDR5)
LSR: 110477628(WDR5)
SCAN: 103818961(WDR5)
GFR: 102037774(WDR5)
FAB: 101812189(WDR5)
PHI: 102100079(WDR5)
PMAJ: 107211986(WDR5)
CCAE: 111937050(WDR5)
CCW: 104688343(WDR5)
ETL: 114059119(WDR5)
FPG: 101923680(WDR5)
FCH: 102048034(WDR5)
CLV: 102098320(WDR5)
EGZ: 104129338(WDR5)
NNI: 104023199(WDR5)
ACUN: 113486537(WDR5)
PADL: 103915262(WDR5)
AAM: 106486992(WDR5)
ASN: 102384300(WDR5)
AMJ: 102557893(WDR5)
PSS: 102443711(WDR5)
CMY: 102935004(WDR5)
CPIC: 101935819(WDR5)
ACS: 100566644(wdr5)
PVT: 110089297(WDR5)
PBI: 103047991(WDR5)
PMUR: 107291027(WDR5)
TSR: 106548360(WDR5)
PMUA: 114589250(WDR5)
GJA: 107106566(WDR5)
XLA: 446809(wdr5.L) 447447(wdr5.S)
XTR: 496891(wdr5)
NPR: 108795635(WDR5)
DRE: 406372(wdr5)
CCAR: 109078979 109098293(wdr5)
IPU: 108278780(wdr5)
PHYP: 113535582(wdr5)
AMEX: 103023146 103033424(wdr5)
EEE: 113573076 113573682(wdr5)
TRU: 101079208(wdr5)
LCO: 104924863(wdr5)
MZE: 101467125(wdr5)
ONL: 100690256(wdr5)
OLA: 101166483(wdr5)
XMA: 102234605(wdr5)
XCO: 114149502(wdr5)
PRET: 103474008(wdr5)
CVG: 107102159(wdr5)
NFU: 107396361(wdr5)
KMR: 108241381(wdr5)
ALIM: 106513572(wdr5)
AOCE: 111563718(wdr5)
CSEM: 103389491(wdr5) 103397940
POV: 109643566(wdr5)
LCF: 108880297(wdr5) 108894557
SDU: 111237447 111237506(wdr5)
SLAL: 111649058 111655952(wdr5)
HCQ: 109530340(wdr5)
BPEC: 110172341(wdr5)
MALB: 109957409 109960757(wdr5)
ELS: 105024177(wdr5)
SFM: 108927192 108938379(wdr5)
LCM: 102363163(WDR5)
CMK: 103182966(wdr5)
RTP: 109926241
BFO: 118421231
CIN: 100176938
SPU: 579376
APLC: 110988617
SKO: 100375790
DME: Dmel_CG10931(CG10931) Dmel_CG17437(wds)
DSI: Dsimw501_GD11312(Dsim_GD11312) Dsimw501_GD16610(Dsim_GD16610)
DAN: 6504881
DVI: 6633369
MDE: 101900923
LCQ: 111679275
AAG: 5580266
AME: 552669
BIM: 100742659
BTER: 100642280
CCAL: 108625612
OBB: 114877620
SOC: 105207713
MPHA: 105838145
AEC: 105148427
ACEP: 105619088
PBAR: 105433387
VEM: 105570420
HST: 105182660
DQU: 106744095
CFO: 105258800
LHU: 105673266
PGC: 109854748
OBO: 105280398
PCF: 106788391
NVI: 100114928
CSOL: 105360713
TCA: 660221
DPA: 109542708
NVL: 108562345
BMOR: 692642(Wds)
BMAN: 114245527
PMAC: 106719638
PRAP: 111004391
HAW: 110374459
TNL: 113494496
PXY: 105398547
DNX: 107169774
AGS: 114125296
RMD: 113552203
BTAB: 109040787
CLEC: 106661058
ZNE: 110835223
FCD: 110848000
TUT: 107362251
DPTE: 113791897
PTEP: 107455599
CEL: CELE_C14B1.4(wdr-5.1) CELE_K04G11.4(wdr-5.2) CELE_ZC302.2(wdr-5.3)
CBR: CBG08899 CBG09206(Cbr-tag-125) CBG09688
BMY: Bm1_28000
OBI: 106875273
LAK: 106154500
SHX: MS3_02750
EGL: EGR_07002
ATH: AT3G49660(WDR5a) AT4G02730(WDR5b)
LJA: Lj4g3v2352060.1(Lj4g3v2352060.1) Lj5g3v0977410.1(Lj5g3v0977410.1)
DOSA: Os03t0725400-01(Os03g0725400) Os07t0572000-01(Os07g0572000)
ZMA: 100216826(pco089076) 100276374 103633326
VCN: VOLCADRAFT_109001(VMUT11)
APRO: F751_0490
SCE: YBR175W(SWD3)
ERC: Ecym_7078
KMX: KLMA_10808(SWD3)
NCS: NCAS_0B01910(NCAS0B01910)
NDI: NDAI_0C05770(NDAI0C05770)
TPF: TPHA_0I01690(TPHA0I01690)
TBL: TBLA_0B04390(TBLA0B04390)
TDL: TDEL_0A05290(TDEL0A05290)
KAF: KAFR_0I00640(KAFR0I00640)
PIC: PICST_32006(SWD3)
CAL: CAALFM_C602170CA(SWD3)
SLB: AWJ20_5017(SWD3)
NCR: NCU03244
NTE: NEUTE1DRAFT72317(NEUTE1DRAFT_72317)
MGR: MGG_04473
SSCK: SPSK_02354
NHE: NECHADRAFT_122274(SWDC2101)
MAW: MAC_03191
MAJ: MAA_04285
CMT: CCM_02300
MBE: MBM_01293
ANI: AN3926.2
ANG: ANI_1_1672094(An11g01650)
ABE: ARB_07942
TVE: TRV_04096
PTE: PTT_04320
ZTR: MYCGRDRAFT_100547(SWDC2401)
SPO: SPBC354.03(swd3)
CNE: CND01430
CNB: CNBD4890
TASA: A1Q1_03324
ABP: AGABI1DRAFT119061(AGABI1DRAFT_119061) AGABI1DRAFT32084(AGABI1DRAFT_32084)
ABV: AGABI2DRAFT115290(AGABI2DRAFT_115290) AGABI2DRAFT186220(AGABI2DRAFT_186220) AGABI2DRAFT62628(AGABI2DRAFT_62628)
DDI: DDB_G0287273(wdr5)
EHI: EHI_117620(157.t00011)
CPV: cgd2_2880
SMIN: v1.2.001462.t1(symbB.v1.2.001462.t1)
CALH: IJ00_02690
 » show all
Reference
  Authors
Patel A, Dharmarajan V, Vought VE, Cosgrove MS
  Title
On the mechanism of multiple lysine methylation by the human mixed lineage leukemia protein-1 (MLL1) core complex.
  Journal
J Biol Chem 284:24242-56 (2009)
DOI:10.1074/jbc.M109.014498
  Sequence
[hsa:11091]
Reference
  Authors
Krogan NJ, Dover J, Khorrami S, Greenblatt JF, Schneider J, Johnston M, Shilatifard A
  Title
COMPASS, a histone H3 (Lysine 4) methyltransferase required for telomeric silencing of gene expression.
  Journal
J Biol Chem 277:10753-5 (2002)
DOI:10.1074/jbc.C200023200
  Sequence
[sce:YBR175W]
Reference
  Authors
Gori F, Divieti P, Demay MB
  Title
Cloning and characterization of a novel WD-40 repeat protein that dramatically accelerates osteoblastic differentiation.
  Journal
J Biol Chem 276:46515-22 (2001)
DOI:10.1074/jbc.M105757200
  Sequence
[hsa:11091]
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