KEGG ORTHOLOGY: K16025

ORTHOLOGY: K16025

Entry

K16025                      KO

Symbol

asm14

Name

methoxymalonate biosynthesis acyl carrier protein

Pathway

map01051

Biosynthesis of ansamycins

map01052

Type I polyketide structures

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01052 Type I polyketide structures
    K16025  asm14; methoxymalonate biosynthesis acyl carrier protein
   01051 Biosynthesis of ansamycins
    K16025  asm14; methoxymalonate biosynthesis acyl carrier protein
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01008 Polyketide biosynthesis proteins
    K16025  asm14; methoxymalonate biosynthesis acyl carrier protein
Polyketide biosynthesis proteins [BR:ko01008]
Polyketide tailoring proteins
  Others
   K16025  asm14; methoxymalonate biosynthesis acyl carrier protein

Genes

PDY:	QJQ58_11880

MBAI:

MB901379_02750

NTP:	CRH09_20595

SGRF:

SGFS_005690 SGFS_014230

SCB:	SCAB_83951

SVL:	Strvi_4990 Strvi_5875 Strvi_6780

SRC:	M271_37835 M271_41245 M271_50130

SMAL:

SMALA_0863 SMALA_1179 SMALA_1271 SMALA_1367

SSOI:

I1A49_00860 I1A49_07820 I1A49_09375 I1A49_09840

SBH:	SBI_09655(ozmE)

SCW:	TU94_03085 TU94_30695

SAMB:

SAM23877_5601(srm36)

SCZ:	ABE83_03045

SLE:	sle_62760(sle_62760)

STRT:

A8713_28280

SCLF:

BB341_27675

SGS:	AVL59_10140

SAUO:

BV401_01110 BV401_08130 BV401_09665 BV401_10140

SSIA:

A7J05_02370

SALJ:

SMD11_1671

SGD:	ELQ87_38735

SQZ:	FQU76_00590 FQU76_32215

SKA:	CP970_02200

SCAV:

CVT27_30480

SRIM:

CP984_12650

SSUB:

CP968_05710

STSU:

B7R87_00480 B7R87_01725 B7R87_31515

SGX:	H4W23_35895

SSPB:

CP982_14320

SHK:	J2N69_35945

SCAE:

IHE65_08975

SANT:

QR300_33400 QR300_40715

SJN:	RI060_20870

SOV:	QZH56_33495

KSK:	KSE_73500(bfmC)

KAB:	B7C62_33095

KIS:	HUT16_05335 HUT16_33225

STRH:

GXP74_17965 GXP74_23585

NAKE:

KGD83_23290

SAIU:

J4H86_01030

AMAZ:

LUW76_46585

SACC:

EYD13_07705 EYD13_10135

AMYB:

AORI:

APRT:

APRE:

AMI:	Amir_3186 Amir_3280

SESP:

BN6_35410

SSYI:

EKG83_24515

KUT:	JJ691_23710(dltC_1)

KPHY:

AOZ06_39660

ACTI:

UA75_16780

ACTA:

C1701_25705

UME:	RM788_50530

MTUA:

MICH:

MCAB:

ACTN:

ACTR:

PLK:	CIK06_12130

PSUU:

Psuf_000460

» show all

Reference

PMID:17076505

Authors

Wenzel SC, Williamson RM, Grunanger C, Xu J, Gerth K, Martinez RA, Moss SJ, Carroll BJ, Grond S, Unkefer CJ, Muller R, Floss HG

Title

On the biosynthetic origin of methoxymalonyl-acyl carrier protein, the substrate for incorporation of "glycolate" units into ansamitocin and soraphen A.

Journal

J Am Chem Soc 128:14325-36 (2006)
DOI:10.1021/ja064408t

Reference

PMID:12060743

Authors

Yu TW, Bai L, Clade D, Hoffmann D, Toelzer S, Trinh KQ, Xu J, Moss SJ, Leistner E, Floss HG

Title

The biosynthetic gene cluster of the maytansinoid antitumor agent ansamitocin from Actinosynnema pretiosum.

Journal

Proc Natl Acad Sci U S A 99:7968-73 (2002)
DOI:10.1073/pnas.092697199

Sequence

[apre:CNX65_16210]

LinkDB

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