KEGG ORTHOLOGY: K16366

ORTHOLOGY: K16366

Entry

K16366 KO

Name

EDN1

Definition

endothelin-1

Pathway

ko04024

cAMP signaling pathway

ko04066

HIF-1 signaling pathway

ko04080

Neuroactive ligand-receptor interaction

ko04270

Vascular smooth muscle contraction

ko04668

TNF signaling pathway

ko04916

Melanogenesis

ko04924

Renin secretion

ko04926

Relaxin signaling pathway

ko04933

AGE-RAGE signaling pathway in diabetic complications

ko05200

Pathways in cancer

ko05410

Hypertrophic cardiomyopathy (HCM)

ko05418

Fluid shear stress and atherosclerosis

Disease

H01884

Auriculocondylar syndrome

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04668 TNF signaling pathway
    K16366  EDN1; endothelin-1
   04066 HIF-1 signaling pathway
    K16366  EDN1; endothelin-1
   04024 cAMP signaling pathway
    K16366  EDN1; endothelin-1
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K16366  EDN1; endothelin-1
09150 Organismal Systems
  09152 Endocrine system
   04926 Relaxin signaling pathway
    K16366  EDN1; endothelin-1
   04916 Melanogenesis
    K16366  EDN1; endothelin-1
   04924 Renin secretion
    K16366  EDN1; endothelin-1
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    K16366  EDN1; endothelin-1
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K16366  EDN1; endothelin-1
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    K16366  EDN1; endothelin-1
   05410 Hypertrophic cardiomyopathy (HCM)
    K16366  EDN1; endothelin-1
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    K16366  EDN1; endothelin-1

Genes

HSA:	1906(EDN1)

PTR:	462437(EDN1)

PPS:	100982777(EDN1)

GGO:	101142752(EDN1)

PON:	100457204(EDN1)

NLE:	100579923(EDN1)

MCC:	699982(EDN1)

MCF:	102115765(EDN1)

CSAB:

103222156(EDN1)

RRO:	104657358(EDN1)

RBB:	108541613(EDN1)

CJC:	100414848(EDN1)

SBQ:	101052988(EDN1)

MMU:	13614(Edn1)

MCAL:

110308576(Edn1)

MPAH:

110334180(Edn1)

RNO:	24323(Edn1)

MUN:	110544244(Edn1)

CGE:	100768493(Edn1)

NGI:	103732886(Edn1)

HGL:	101724063(Edn1)

CCAN:

109676387(Edn1)

OCU:	100009270(EDN1)

TUP:	102475703(EDN1)

CFA:	403424(EDN1)

VVP:	112920459(EDN1)

AML:	100470926(EDN1)

UMR:	103664910(EDN1)

UAH:	113264459(EDN1)

ORO:	101377023(EDN1)

ELK:

111156738

FCA:	494214(EDN1)

PTG:	102969504(EDN1)

PPAD:

109249630(EDN1)

AJU:	106974187(EDN1)

BTA:	281137(EDN1)

BOM:	102272983(EDN1)

BIU:	109577403(EDN1)

BBUB:

102408650(EDN1)

CHX:	102175912(EDN1)

OAS:	443498(EDN1)

SSC:	396915(EDN1)

CFR:	102508685(EDN1)

CDK:	105102504(EDN1)

BACU:

103016665(EDN1)

LVE:	103074734(EDN1)

OOR:	101277994(EDN1)

DLE:	111181269(EDN1)

PCAD:

102990236(EDN1)

ECB:	100034060(EDN1)

EPZ:	103552897(EDN1)

EAI:	106842476(EDN1)

MYB:	102263857(EDN1)

MYD:	102756144(EDN1)

MNA:	107530403(EDN1)

HAI:	109375416(EDN1)

DRO:	112309401(EDN1)

PALE:

102895320(EDN1)

RAY:	107515476(EDN1)

MJV:	108408339(EDN1)

LAV:	100672459(EDN1)

TMU:

101349561

MDO:	100026601(EDN1)

SHR:	100918955(EDN1)

PCW:	110224099(EDN1)

OAA:	100084367(EDN1)

GGA:	420854(EDN1)

MGP:	104910143(EDN1)

CJO:	107309703(EDN1)

NMEL:

110394591(EDN1)

APLA:

101803012(EDN1)

ACYG:

106044328(EDN1)

TGU:	100219314(EDN1)

LSR:	110473713(EDN1)

SCAN:

103815071(EDN1)

GFR:	102041445(EDN1)

FAB:	101815457(EDN1)

PHI:	102105741(EDN1)

PMAJ:

107199930(EDN1)

CCAE:

111923790(EDN1)

CCW:	104691397(EDN1)

ETL:	114061304(EDN1)

FPG:	101921903(EDN1)

FCH:	102058534(EDN1)

CLV:	102085468(EDN1)

EGZ:	104125502(EDN1)

NNI:	104021891(EDN1)

ACUN:

113477413(EDN1)

PADL:

103919091(EDN1)

AAM:	106482527(EDN1)

ASN:	102379277(EDN1)

AMJ:	102571363(EDN1)

PSS:	102444660(EDN1)

CMY:	102930019(EDN1)

CPIC:

101935305(EDN1)

ACS:	100554891(edn1)

PVT:	110091723(EDN1)

PBI:	103050714(EDN1)

PMUR:

107283011(EDN1)

PMUA:

114600898(EDN1)

XLA:	100036806(edn1.S) 100158354(edn1.L)

XTR:	100144700(edn1)

NPR:

108798928

DRE:	58032(edn1)

SRX:	107727565 107734027 107738957

SANH:

107669974 107681615 107689457

SGH:	107551767 107553437 107559691

CCAR:

109064665

IPU:	108257472(edn1)

PHYP:

113524460

AMEX:

103038749

EEE:

113580419

TRU:	101069760 105417514

LCO:

104939271

NCC:

104963382

MZE:	101467161(edn1)

ONL:	100689848(edn1)

OLA:	101157583 101161654(edn1)

XMA:	102217021(edn1)

XCO:

114156283

PRET:

103473010(edn1)

CVG:

NFU:

KMR:

ALIM:

CSEM:

103393940(edn1)

POV:

109640492

LCF:

108899556

SDU:	111230592(edn1)

SLAL:

111655032

HCQ:	109513567(edn1)

BPEC:

110159270(edn1)

MALB:

109958566(edn1)

SASA:

106570392 106571542 106589028 106607917

OTW:	112229569 112236432 112251717

SALP:

111954543 111954886 112074729

ELS:	105012590(edn1)

SFM:	108931832(edn1)

PKI:	111843869(edn1)

LCM:	102347799(EDN1)

CMK:	103187042(edn1)

RTP:

109921618

» show all

Reference

PMID:3282927

Authors

Itoh Y, Yanagisawa M, Ohkubo S, Kimura C, Kosaka T, Inoue A, Ishida N, Mitsui Y, Onda H, Fujino M, et al.

Title

Cloning and sequence analysis of cDNA encoding the precursor of a human endothelium-derived vasoconstrictor peptide, endothelin: identity of human and porcine endothelin.

Journal

FEBS Lett 231:440-4 (1988)
DOI:10.1016/0014-5793(88)80867-6

Sequence

[hsa:1906]

Reference

PMID:20466059

Authors

Khimji AK, Rockey DC

Title

Endothelin--biology and disease.

Journal

Cell Signal 22:1615-25 (2010)
DOI:10.1016/j.cellsig.2010.05.002

LinkDB

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