KEGG   ORTHOLOGY: K18026Help
Entry
K18026                      KO                                     

Name
PTPN2, PTPT
Definition
tyrosine-protein phosphatase non-receptor type 2 [EC:3.1.3.48]
Pathway
ko04630  JAK-STAT signaling pathway
Disease
H00408  Type 1 diabetes mellitus
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 Jak-STAT signaling pathway
    K18026  PTPN2, PTPT; tyrosine-protein phosphatase non-receptor type 2
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins
    K18026  PTPN2, PTPT; tyrosine-protein phosphatase non-receptor type 2
Enzymes [BR:ko01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.48  protein-tyrosine-phosphatase
     K18026  PTPN2, PTPT; tyrosine-protein phosphatase non-receptor type 2
Protein phosphatases and associated proteins [BR:ko01009]
 Protein tyrosine phosphatases (PTPs)
  Class I PTPs (Classical)
   Non-receptor PTPs
    K18026  PTPN2, PTPT; tyrosine-protein phosphatase non-receptor type 2
BRITE hierarchy
Other DBs
GO: 0004725
Genes
HSA: 5771(PTPN2)
PTR: 455504(PTPN2)
PPS: 100969647(PTPN2)
GGO: 101137356(PTPN2)
PON: 100445655(PTPN2)
NLE: 100603034(PTPN2)
MCC: 114673846(PTPN2)
MCF: 101866630(PTPN2)
CSAB: 103222817(PTPN2)
RRO: 104671929(PTPN2)
RBB: 108533096(PTPN2)
CJC: 100412533(PTPN2)
SBQ: 101027825(PTPN2)
MMU: 19255(Ptpn2)
MCAL: 110285003(Ptpn2)
MPAH: 110333049(Ptpn2)
RNO: 117063(Ptpn2)
MUN: 110562689(Ptpn2)
CGE: 103163089(Ptpn2)
NGI: 103741724(Ptpn2)
HGL: 101725549(Ptpn2)
CCAN: 109685072(Ptpn2)
OCU: 100338151(PTPN2)
TUP: 102485713(PTPN2)
CFA: 490563(PTPN2)
VVP: 112925308(PTPN2)
AML: 100483443(PTPN2)
UMR: 103673356(PTPN2)
UAH: 113245907(PTPN2)
ORO: 101383123(PTPN2)
ELK: 111142429
FCA: 101095923(PTPN2)
PTG: 102953894(PTPN2)
PPAD: 109257633(PTPN2)
AJU: 106981464(PTPN2)
BTA: 540888(PTPN2)
BOM: 102281612(PTPN2)
BIU: 109577870(PTPN2)
BBUB: 102414227(PTPN2)
CHX: 102179903(PTPN2)
OAS: 101106987(PTPN2)
SSC: 100171401(PTPN2)
CFR: 102509923(PTPN2)
CDK: 105086470(PTPN2)
BACU: 103014463(PTPN2)
LVE: 103091407(PTPN2)
OOR: 101279319(PTPN2)
DLE: 111163085(PTPN2)
PCAD: 102987085(PTPN2)
ECB: 100057795(PTPN2)
EPZ: 103554305(PTPN2)
EAI: 106828641(PTPN2)
MYB: 102241649(PTPN2)
MYD: 102756120(PTPN2)
MNA: 107525236(PTPN2)
HAI: 109396445(PTPN2)
DRO: 112322685(PTPN2)
PALE: 102880076(PTPN2)
RAY: 107497714(PTPN2)
LAV: 100654678(PTPN2)
TMU: 101346964
MDO: 100018164(PTPN2)
SHR: 100935022(PTPN2)
PCW: 110207799(PTPN2)
OAA: 100083956(PTPN2)
GGA: 396409(PTPN2)
MGP: 100545675(PTPN2)
CJO: 107310024(PTPN2)
NMEL: 110393189(PTPN2)
APLA: 101802229(PTPN2)
ACYG: 106034930(PTPN2)
TGU: 100225009(PTPN2)
LSR: 110469243(PTPN2)
SCAN: 103826514(PTPN2)
GFR: 102033724(PTPN2)
FAB: 101807816(PTPN2)
PHI: 102110181(PTPN2)
PMAJ: 107199798(PTPN2)
CCAE: 111924854(PTPN2)
CCW: 104687339(PTPN2)
ETL: 114058219(PTPN2)
FPG: 101917001(PTPN2)
FCH: 102048689(PTPN2)
CLV: 102096578(PTPN2)
EGZ: 104132865(PTPN2)
NNI: 104017656(PTPN2)
ACUN: 113476100(PTPN2)
PADL: 103912275(PTPN2)
AAM: 106484308(PTPN2)
ASN: 102367862(PTPN2)
AMJ: 102567939(PTPN2)
PSS: 102456619(PTPN2)
CMY: 102945334(PTPN2)
CPIC: 101935962(PTPN2)
ACS: 100558082(ptpn2)
PVT: 110078033(PTPN2)
PBI: 103053565(PTPN2)
PMUR: 107288173(PTPN2)
TSR: 106545742(PTPN2)
PMUA: 114600765(PTPN2)
GJA: 107113098(PTPN2)
XLA: 431888(ptpn2.L) 446745(ptpn2.S)
XTR: 100492067(ptpn2)
NPR: 108787318(PTPN2)
DRE: 393438(ptpn2a) 561613(ptpn2b)
IPU: 108257293(ptpn2) 108272944
TRU: 101063867(ptpn2) 101065622
LCO: 104918639 104936248(ptpn2)
XMA: 102224419(ptpn2) 102229317
XCO: 114144543(ptpn2) 114155628
PRET: 103465904(ptpn2) 103472442
NFU: 107378879(ptpn2) 107394678
KMR: 108234147(ptpn2) 108241382
ALIM: 106518165 106519263(ptpn2)
AOCE: 111565512(ptpn2) 111566760
CSEM: 103388897(ptpn2) 103394276
LCF: 108876292(ptpn2) 108898162
SDU: 111223475 111227823(ptpn2)
HCQ: 109514592 109521924(ptpn2)
BPEC: 110167244 110171483(ptpn2)
MALB: 109958764 109963839(ptpn2)
OTW: 112229372(ptpn2) 112242499
SALP: 112076838
PKI: 111844781 111852532(ptpn2)
LCM: 102364029(PTPN2)
CMK: 103179645(ptpn2)
RTP: 109933050(ptpn2)
PCAN: 112553188
ADF: 107356737
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Simoncic PD, Lee-Loy A, Barber DL, Tremblay ML, McGlade CJ
  Title
The T cell protein tyrosine phosphatase is a negative regulator of janus family kinases 1 and 3.
  Journal
Curr Biol 12:446-53 (2002)
DOI:10.1016/S0960-9822(02)00697-8
  Sequence
[hsa:5771] [mmu:19255]
LinkDB All DBs

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