KEGG   ORTHOLOGY: K18052Help
Entry
K18052                      KO                                     

Name
PRKCQ
Definition
novel protein kinase C theta type [EC:2.7.11.13]
Pathway
ko04064  NF-kappa B signaling pathway
ko04140  Autophagy - animal
ko04270  Vascular smooth muscle contraction
ko04658  Th1 and Th2 cell differentiation
ko04659  Th17 cell differentiation
ko04660  T cell receptor signaling pathway
ko04750  Inflammatory mediator regulation of TRP channels
ko04920  Adipocytokine signaling pathway
ko04931  Insulin resistance
ko05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Disease
H00408  Type 1 diabetes mellitus
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04064 NF-kappa B signaling pathway
    K18052  PRKCQ; novel protein kinase C theta type
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    K18052  PRKCQ; novel protein kinase C theta type
 09150 Organismal Systems
  09151 Immune system
   04660 T cell receptor signaling pathway
    K18052  PRKCQ; novel protein kinase C theta type
   04658 Th1 and Th2 cell differentiation
    K18052  PRKCQ; novel protein kinase C theta type
   04659 Th17 cell differentiation
    K18052  PRKCQ; novel protein kinase C theta type
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    K18052  PRKCQ; novel protein kinase C theta type
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    K18052  PRKCQ; novel protein kinase C theta type
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    K18052  PRKCQ; novel protein kinase C theta type
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    K18052  PRKCQ; novel protein kinase C theta type
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    K18052  PRKCQ; novel protein kinase C theta type
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K18052  PRKCQ; novel protein kinase C theta type
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.13  protein kinase C
     K18052  PRKCQ; novel protein kinase C theta type
Protein kinases [BR:ko01001]
 Serine/threonine kinases: AGC group
  PKC family [OT]
   K18052  PRKCQ; novel protein kinase C theta type
BRITE hierarchy
Other DBs
GO: 0004699
Genes
HSA: 5588(PRKCQ)
PTR: 450288(PRKCQ)
PPS: 100995594(PRKCQ)
GGO: 101127426(PRKCQ)
PON: 100443896(PRKCQ)
NLE: 100583445(PRKCQ)
MCC: 722559(PRKCQ)
MCF: 102125438(PRKCQ)
CSAB: 103237845(PRKCQ)
RRO: 104664850(PRKCQ)
RBB: 108529909(PRKCQ)
CJC: 100415241(PRKCQ)
SBQ: 101035951(PRKCQ)
MMU: 18761(Prkcq)
MCAL: 110288992(Prkcq)
MPAH: 110333780(Prkcq)
RNO: 85420(Prkcq)
MUN: 110556894(Prkcq)
CGE: 100762470(Prkcq)
NGI: 103727298(Prkcq)
HGL: 101724103(Prkcq)
CCAN: 109698517(Prkcq)
OCU: 103350889(PRKCQ)
TUP: 102498896(PRKCQ)
CFA: 478013(PRKCQ)
VVP: 112933595(PRKCQ)
AML: 100484647(PRKCQ)
UMR: 103676251(PRKCQ)
UAH: 113241147(PRKCQ)
ORO: 101381252(PRKCQ)
FCA: 101100730(PRKCQ)
PTG: 102953214(PRKCQ) 102971297
AJU: 106982347(PRKCQ)
BTA: 505901(PRKCQ)
BOM: 102273710(PRKCQ)
BIU: 109567889(PRKCQ)
BBUB: 102403335(PRKCQ)
PHD: 102324605(PRKCQ)
CHX: 102170884(PRKCQ)
OAS: 101113426(PRKCQ)
SSC: 100621326(PRKCQ)
CFR: 102517668(PRKCQ)
CDK: 105091352(PRKCQ)
BACU: 102997547(PRKCQ)
LVE: 103088766(PRKCQ)
OOR: 101276634(PRKCQ)
DLE: 111177982(PRKCQ)
PCAD: 102982768(PRKCQ)
ECB: 100070207(PRKCQ)
EPZ: 103557074(PRKCQ)
EAI: 106831239(PRKCQ)
MYB: 102242050(PRKCQ)
MYD: 102767625(PRKCQ)
MNA: 107542460(PRKCQ)
HAI: 109383803(PRKCQ)
RSS: 109450679(PRKCQ)
DRO: 112320743(PRKCQ)
PALE: 102892408(PRKCQ)
RAY: 107505977(PRKCQ)
LAV: 100657357(PRKCQ)
TMU: 101355872
MDO: 100010321(PRKCQ)
SHR: 100919789(PRKCQ)
PCW: 110193342(PRKCQ)
OAA: 100085025(PRKCQ)
GGA: 776459(PRKCQ)
MGP: 100547919(PRKCQ)
CJO: 107315299(PRKCQ)
NMEL: 110392242(PRKCQ)
APLA: 101804738(PRKCQ)
ACYG: 106038746(PRKCQ)
TGU: 100232581(PRKCQ)
LSR: 110470915(PRKCQ)
SCAN: 103822473(PRKCQ)
GFR: 102035650(PRKCQ)
FAB: 101807238(PRKCQ)
PHI: 102104222(PRKCQ)
PMAJ: 107205082(PRKCQ)
CCAE: 111923214(PRKCQ)
CCW: 104694520(PRKCQ)
ETL: 114067845(PRKCQ)
FPG: 101923479(PRKCQ)
FCH: 102055219(PRKCQ)
CLV: 102091403(PRKCQ)
EGZ: 104134835(PRKCQ)
NNI: 104010494(PRKCQ)
ACUN: 113490778(PRKCQ) 113490787
PADL: 103920828(PRKCQ)
AAM: 106484941(PRKCQ)
ASN: 102388307(PRKCQ)
AMJ: 106737047(PRKCQ)
PSS: 102453686(PRKCQ)
CMY: 102938526(PRKCQ)
CPIC: 101932141(PRKCQ)
ACS: 100566301(prkcq) 103282196
PBI: 103056759(PRKCQ)
PMUR: 107298816(PRKCQ)
XTR: 100038268(prkcq)
NPR: 108794777(PRKCQ)
DRE: 555521(prkcq)
SRX: 107728508(prkcq) 107748461
SANH: 107666947(prkcq) 107675981
SGH: 107555829 107597022(prkcq)
IPU: 108279855(prkcq)
PHYP: 113532328(prkcq)
AMEX: 103040891(prkcq)
EEE: 113587890(prkcq)
TRU: 101069776(prkcq)
LCO: 104933094(prkcq)
NCC: 104948477 104958569(prkcq)
MZE: 101466316(prkcq)
OLA: 101167165(prkcq)
XMA: 102232226(prkcq)
XCO: 114160610(prkcq)
PRET: 103459790(prkcq)
NFU: 107387306(prkcq)
KMR: 108233171(prkcq)
AOCE: 111574060(prkcq)
CSEM: 103383100(prkcq)
POV: 109641482
LCF: 108895932(prkcq)
SDU: 111224634(prkcq)
HCQ: 109532640(prkcq)
BPEC: 110161495(prkcq)
MALB: 109967605(prkcq)
SASA: 106576193 106609272(prkcq)
SALP: 111949731(prkcq) 111951275
ELS: 105028527(prkcq)
SFM: 108931662(prkcq) 108935967
PKI: 111842352(prkcq) 111860125
LCM: 102348224(PRKCQ)
CMK: 103187922(prkcq)
AQU: 100631608
ABV: AGABI2DRAFT116898(AGABI2DRAFT_116898)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:8444877
  Authors
Baier G, Telford D, Giampa L, Coggeshall KM, Baier-Bitterlich G, Isakov N, Altman A
  Title
Molecular cloning and characterization of PKC theta, a novel member of the protein kinase C (PKC) gene family expressed predominantly in hematopoietic cells.
  Journal
J Biol Chem 268:4997-5004 (1993)
  Sequence
[hsa:5588]
Reference
  Authors
Altman A, Villalba M
  Title
Protein kinase C-theta (PKC theta): a key enzyme in T cell life and death.
  Journal
J Biochem 132:841-6 (2002)
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