KEGG   ORTHOLOGY: K22429Help
Entry
K22429                      KO                                     

Name
FGF21
Definition
fibroblast growth factor 21
Pathway
ko04010  MAPK signaling pathway
ko04014  Ras signaling pathway
ko04015  Rap1 signaling pathway
ko04151  PI3K-Akt signaling pathway
ko04714  Thermogenesis
ko04810  Regulation of actin cytoskeleton
ko05200  Pathways in cancer
ko05218  Melanoma
ko05224  Breast cancer
ko05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    K22429  FGF21; fibroblast growth factor 21
   04015 Rap1 signaling pathway
    K22429  FGF21; fibroblast growth factor 21
   04010 MAPK signaling pathway
    K22429  FGF21; fibroblast growth factor 21
   04151 PI3K-Akt signaling pathway
    K22429  FGF21; fibroblast growth factor 21
 09140 Cellular Processes
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    K22429  FGF21; fibroblast growth factor 21
 09150 Organismal Systems
  09159 Environmental adaptation
   04714 Thermogenesis
    K22429  FGF21; fibroblast growth factor 21
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K22429  FGF21; fibroblast growth factor 21
  09162 Cancer: specific types
   05226 Gastric cancer
    K22429  FGF21; fibroblast growth factor 21
   05218 Melanoma
    K22429  FGF21; fibroblast growth factor 21
   05224 Breast cancer
    K22429  FGF21; fibroblast growth factor 21
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors
    K22429  FGF21; fibroblast growth factor 21
   00536 Glycosaminoglycan binding proteins
    K22429  FGF21; fibroblast growth factor 21
Cytokines and growth factors [BR:ko04052]
 Growth factors
  Growth factors (RTK binding)
   K22429  FGF21; fibroblast growth factor 21
Glycosaminoglycan binding proteins [BR:ko00536]
 Heparan sulfate / Haparin
  Growth factors/receptors
   K22429  FGF21; fibroblast growth factor 21
BRITE hierarchy
Other DBs
GO: 0005104
Genes
HSA: 26291(FGF21)
PTR: 468948(FGF21)
PPS: 100975521(FGF21)
GGO: 101149990(FGF21)
PON: 100447289(FGF21)
NLE: 100590773(FGF21)
MCC: 718288(FGF21)
MCF: 102126624(FGF21)
CSAB: 103234997(FGF21)
RRO: 104666549(FGF21)
CJC: 100389889(FGF21)
SBQ: 101048392(FGF21)
MMU: 56636(Fgf21)
MCAL: 110299358(Fgf21)
MPAH: 110338839(Fgf21)
RNO: 170580(Fgf21)
MUN: 110550501(Fgf21)
CGE: 100757339(Fgf21)
NGI: 103743629(Fgf21)
HGL: 101717974(Fgf21)
CCAN: 109682677(Fgf21)
OCU: 100356340(FGF21)
TUP: 102474175(FGF21)
CFA: 484395(FGF21)
VVP: 112931222(FGF21)
AML: 100478145(FGF21)
UMR: 103657101(FGF21)
UAH: 113243199(FGF21)
ORO: 101373782(FGF21)
ELK: 111160539
FCA: 101080595(FGF21)
PTG: 102963142(FGF21)
PPAD: 109253108(FGF21)
AJU: 106988712(FGF21)
BTA: 785576(FGF21)
BOM: 102282265(FGF21)
BIU: 109572074(FGF21)
BBUB: 102394633(FGF21)
CHX: 102185860(FGF21)
OAS: 101108510(FGF21)
SSC: 100302504(FGF21)
CFR: 102514176(FGF21)
CDK: 105102899(FGF21)
BACU: 103016083(FGF21)
LVE: 103081969(FGF21)
OOR: 101287388(FGF21)
DLE: 111180649(FGF21)
PCAD: 102973747(FGF21)
ECB: 100054542(FGF21)
EPZ: 103553325(FGF21)
EAI: 106838258(FGF21)
MYB: 102260667(FGF21)
MYD: 102768942(FGF21)
MNA: 107531851(FGF21)
HAI: 109391024(FGF21)
DRO: 112310055(FGF21)
PALE: 102886540(FGF21)
RAY: 107498854(FGF21)
MJV: 108400332(FGF21)
LAV: 100661893(FGF21)
TMU: 101356236
SHR: 100931317(FGF21)
PCW: 110219692(FGF21)
NMEL: 110391341
ASN: 102386963(FGF21)
AMJ: 102565552(FGF21)
CMY: 102941236
CPIC: 101934102(FGF21)
ACS: 100564275(fgf21)
PVT: 110078593(FGF21)
PBI: 103064082(FGF21)
PMUR: 107282458(FGF21)
TSR: 106538689(FGF21)
PMUA: 114582678(FGF21)
XTR: 105947943
DRE: 724048(fgf21)
IPU: 108263130
PHYP: 113546510
EEE: 113589172
TRU: 101073344(fgf21)
LCO: 104920702(fgf21)
MZE: 101485258(fgf21)
ONL: 100703128
OLA: 111946374
XMA: 102232669
XCO: 114153231
PRET: 103481230
CVG: 107101219
NFU: 107387534(fgf21)
KMR: 108237167
ALIM: 106517425
AOCE: 111584608
CSEM: 103381999(fgf21)
POV: 109626716(fgf21)
LCF: 108884404
SDU: 111219763(fgf21)
SLAL: 111658620(fgf21)
HCQ: 109524005
MALB: 109963646
SASA: 106579352
OTW: 112223261
SALP: 111977638
ELS: 109615792(fgf21)
LCM: 102367098
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Nishimura T, Nakatake Y, Konishi M, Itoh N
  Title
Identification of a novel FGF, FGF-21, preferentially expressed in the liver.
  Journal
Biochim Biophys Acta 1492:203-6 (2000)
DOI:10.1016/S0167-4781(00)00067-1
  Sequence
[hsa:26291]
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