KEGG   ORTHOLOGY: K00445Help
Entry
K00445                      KO                                     

Name
WNT6
Definition
wingless-type MMTV integration site family, member 6
Pathway
ko04150  mTOR signaling pathway
ko04310  Wnt signaling pathway
ko04390  Hippo signaling pathway
ko04550  Signaling pathways regulating pluripotency of stem cells
ko04916  Melanogenesis
ko04934  Cushing syndrome
ko05165  Human papillomavirus infection
ko05200  Pathways in cancer
ko05205  Proteoglycans in cancer
ko05217  Basal cell carcinoma
ko05224  Breast cancer
ko05225  Hepatocellular carcinoma
ko05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    K00445  WNT6; wingless-type MMTV integration site family, member 6
   04390 Hippo signaling pathway
    K00445  WNT6; wingless-type MMTV integration site family, member 6
   04150 mTOR signaling pathway
    K00445  WNT6; wingless-type MMTV integration site family, member 6
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    K00445  WNT6; wingless-type MMTV integration site family, member 6
 09150 Organismal Systems
  09152 Endocrine system
   04916 Melanogenesis
    K00445  WNT6; wingless-type MMTV integration site family, member 6
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K00445  WNT6; wingless-type MMTV integration site family, member 6
   05205 Proteoglycans in cancer
    K00445  WNT6; wingless-type MMTV integration site family, member 6
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    K00445  WNT6; wingless-type MMTV integration site family, member 6
   05226 Gastric cancer
    K00445  WNT6; wingless-type MMTV integration site family, member 6
   05217 Basal cell carcinoma
    K00445  WNT6; wingless-type MMTV integration site family, member 6
   05224 Breast cancer
    K00445  WNT6; wingless-type MMTV integration site family, member 6
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    K00445  WNT6; wingless-type MMTV integration site family, member 6
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    K00445  WNT6; wingless-type MMTV integration site family, member 6
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   00536 Glycosaminoglycan binding proteins
    K00445  WNT6; wingless-type MMTV integration site family, member 6
Glycosaminoglycan binding proteins [BR:ko00536]
 Heparan sulfate / Haparin
  Morphogens
   K00445  WNT6; wingless-type MMTV integration site family, member 6
BRITE hierarchy
Genes
HSA: 7475(WNT6)
PTR: 742467(WNT6)
PPS: 100987794(WNT6)
GGO: 101132496(WNT6)
PON: 100440643(WNT6)
NLE: 100606818(WNT6)
MCC: 700573(WNT6)
MCF: 102132660(WNT6)
CSAB: 103217884(WNT6)
RRO: 104660036(WNT6)
RBB: 108518481(WNT6)
CJC: 100394855(WNT6)
SBQ: 101028364(WNT6)
MMU: 22420(Wnt6)
MCAL: 110299810(Wnt6)
MPAH: 110321884(Wnt6)
RNO: 316526(Wnt6)
MUN: 110566399(Wnt6)
CGE: 100751289(Wnt6)
NGI: 103727729(Wnt6)
HGL: 101698823(Wnt6)
CCAN: 109693790(Wnt6)
OCU: 100348986(WNT6)
TUP: 102483667(WNT6)
CFA: 488527(WNT6)
VVP: 112922542(WNT6)
AML: 100467896(WNT6)
UAH: 113250444(WNT6)
ORO: 101374890(WNT6)
FCA: 101099392(WNT6)
PTG: 102956004(WNT6)
PPAD: 109265051(WNT6)
AJU: 106970073(WNT6)
BTA: 505075(WNT6)
BOM: 102286828(WNT6)
BIU: 109570782(WNT6)
BBUB: 102407032(WNT6)
CHX: 108637658(WNT6)
OAS: 101111785(WNT6)
SSC: 100622044(WNT6)
CFR: 102511574(WNT6)
CDK: 105096131(WNT6)
BACU: 102997453(WNT6)
LVE: 103079243(WNT6)
OOR: 101288015(WNT6)
DLE: 111172090(WNT6)
PCAD: 102993713(WNT6)
ECB: 100058824(WNT6)
EPZ: 103567913(WNT6)
EAI: 106838461(WNT6)
MYB: 102256374(WNT6)
MYD: 102757803(WNT6)
MNA: 107524769(WNT6)
HAI: 109380535(WNT6)
DRO: 112308052(WNT6)
PALE: 102882368(WNT6)
RAY: 107516780(WNT6)
MJV: 108390505(WNT6)
LAV: 100675069(WNT6)
TMU: 101341737
MDO: 100010861(WNT6)
SHR: 100933826(WNT6)
PCW: 110219493(WNT6)
OAA: 100089786(WNT6)
GGA: 395235(WNT6)
MGP: 100540128(WNT6)
CJO: 107317037(WNT6)
NMEL: 110400365(WNT6)
APLA: 101803438(WNT6)
ACYG: 106039313(WNT6)
TGU: 100230318(WNT6)
LSR: 110468403(WNT6)
SCAN: 103814356(WNT6)
GFR: 102035490(WNT6)
FAB: 101819686(WNT6)
PHI: 102100841(WNT6)
PMAJ: 107207801(WNT6)
CCAE: 111931742(WNT6) 111943653
CCW: 104693964(WNT6)
ETL: 114055668(WNT6)
FPG: 101921385(WNT6)
FCH: 102054753(WNT6)
CLV: 102085008(WNT6)
EGZ: 104132404(WNT6)
NNI: 104010067(WNT6)
ACUN: 113482396(WNT6)
PADL: 103917663(WNT6)
AAM: 106499139(WNT6)
ASN: 102377243(WNT6)
AMJ: 106737397(WNT6)
PSS: 102457308
CPIC: 101949600(WNT6)
ACS: 100565609(wnt6)
PVT: 110078170(WNT6)
PBI: 103054454(WNT6)
PMUR: 107292513(WNT6)
TSR: 106540757(WNT6)
PMUA: 114603052(WNT6)
GJA: 107107564(WNT6)
XLA: 108701298(wnt6.L) 378676(wnt6.S)
XTR: 101733784(wnt6)
NPR: 108801546(WNT6)
DRE: 100332722(wnt6a) 561831(wnt6b)
IPU: 108266110(wnt6) 108273177
PHYP: 113523750(wnt6) 113538450
AMEX: 103038704 103041984(wnt6)
EEE: 113574053 113591172(wnt6)
TRU: 101062888(wnt6)
LCO: 104919603(wnt6)
NCC: 104943745(wnt6)
MZE: 101474169(wnt6)
ONL: 100695021(wnt6)
OLA: 101174712(wnt6)
XMA: 102234174(wnt6)
XCO: 114148282(wnt6)
PRET: 103460530(wnt6)
CVG: 107092662(wnt6)
NFU: 107390192(wnt6)
KMR: 108238486(wnt6)
ALIM: 106523158(wnt6)
AOCE: 111580967(wnt6)
POV: 109631098(wnt6)
LCF: 108902815(wnt6)
SDU: 111218508(wnt6)
SLAL: 111668743(wnt6)
HCQ: 109522420(wnt6)
BPEC: 110156189(wnt6)
MALB: 109964395(wnt6)
SASA: 106581837(wnt6) 106586152
SALP: 111972696 111974089(wnt6)
ELS: 105029531(wnt6)
SFM: 108927964(wnt6)
PKI: 111848415(wnt6) 111858301
LCM: 102350297 102352652(WNT6)
SPU: 585147
APLC: 110984744
SKO: 100313763(Wnt6)
DME: Dmel_CG4969(Wnt6)
DER: 6542672
DSI: Dsimw501_GD23460(Dsim_wg)
DSR: 110182670
DPE: 6589315
DMN: 108162806
DWI: 6644099
DAZ: 108611686
DNV: 108658171
DHE: 111602345
MDE: 101898284
LCQ: 111677056
AAG: 5564830
AME: 413501
BIM: 100745430
BTER: 100647833
CCAL: 108622250
OBB: 114871802
SOC: 105200052
MPHA: 105838834
AEC: 105150855
ACEP: 105618731
PBAR: 105429522
VEM: 105566204
HST: 105189290
DQU: 106746483
CFO: 105258968
LHU: 105676116
PGC: 109859095
OBO: 105285325
NVI: 100119613
CSOL: 105367707
TCA: 656429(Wnt6)
DPA: 109545719
NVL: 108563654
BMOR: 101741216
PMAC: 106714253
PRAP: 110994201
HAW: 110371053
TNL: 113501221
PXY: 105397939
BTAB: 109044640
ZNE: 110828845
FCD: 110849830
DPX: DAPPUDRAFT_290641(WNT6)
DPTE: 113795868
PTEP: 107438387
PCAN: 112559562
CRG: 105348241
MYI: 110462024
OBI: 106878314
LAK: 106180551
EPA: 110250756
ADF: 107333377
AMIL: 114957169
PDAM: 113671496
SPIS: 111330934
DGT: 114517724
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Kirikoshi H, Sekihara H, Katoh M
  Title
WNT10A and WNT6, clustered in human chromosome 2q35 region with head-to-tail manner, are strongly coexpressed in SW480 cells.
  Journal
Biochem Biophys Res Commun 283:798-805 (2001)
DOI:10.1006/bbrc.2001.4855
  Sequence
[hsa:7475]
Reference
  Authors
Yuan G, Regel I, Lian F, Friedrich T, Hitkova I, Hofheinz RD, Strobel P, Langer R, Keller G, Rocken C, Zimmermann W, Schmid RM, Ebert MP, Burgermeister E
  Title
WNT6 is a novel target gene of caveolin-1 promoting chemoresistance to epirubicin in human gastric cancer cells.
  Journal
Oncogene 32:375-87 (2013)
DOI:10.1038/onc.2012.40
  Sequence
[hsa:7475]
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