KEGG   ORTHOLOGY: K00478
Entry
K00478                      KO                                     

Name
HR
Definition
[histone H3]-dimethyl-L-lysine9 demethylase [EC:1.14.11.65]
Disease
H00780  Atrichia with papular lesions
H00784  Localized autosomal recessive hypotrichosis
H00786  Hereditary hypotrichosis simplex
H00858  Marie-Unna hereditary hypotrichosis
H01158  Alopecia universalis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins
    K00478  HR; [histone H3]-dimethyl-L-lysine9 demethylase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.11  With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
    1.14.11.65  [histone H3]-dimethyl-L-lysine9 demethylase
     K00478  HR; [histone H3]-dimethyl-L-lysine9 demethylase
Chromosome and associated proteins [BR:ko03036]
 Eukaryotic type
  Histone modification proteins
   Histone demethylases
    K00478  HR; [histone H3]-dimethyl-L-lysine9 demethylase
Other DBs
GO: 0032454
Genes
HSA: 55806(HR)
PTR: 464040(HR)
PPS: 100980801(HR)
GGO: 101132441(HR)
PON: 100451474(HR)
NLE: 100594054(HR)
MCC: 574164(HR)
MCF: 102146603(HR)
CSAB: 103215441(HR)
RRO: 104663955(HR)
RBB: 108521323(HR)
CJC: 100400684(HR)
SBQ: 101041467(HR)
MMU: 15460(Hr)
MCAL: 110309466(Hr)
MPAH: 110325567(Hr)
RNO: 60563(Hr)
MUN: 110551667(Hr)
CGE: 100765886(Hr)
NGI: 103747778(Hr)
HGL: 101710794(Hr)
CCAN: 109690461(Hr)
OCU: 100357019(HR)
TUP: 102497988(HR)
CFA: 486130(HR)
VVP: 112926824(HR)
AML: 100478044(HR)
UMR: 103673344(HR)
UAH: 113270010(HR)
ORO: 101381177(HR)
ELK: 111155178
FCA: 101090097(HR)
PTG: 102971648(HR)
PPAD: 109277357(HR)
AJU: 106981121(HR)
BTA: 785815(HR)
BOM: 102284413(HR)
BIU: 109563100(HR)
BBUB: 102411447(HR)
CHX: 102171151(HR)
OAS: 443241(HR)
SSC: 397617(HR)
CFR: 102517929(HR)
CDK: 105102729(HR)
BACU: 103014592(HR)
LVE: 103089845(HR)
OOR: 101289157(HR)
DLE: 111169011(HR)
PCAD: 102993125(HR)
ECB: 100053727(HR)
EPZ: 103566264(HR)
EAI: 106847718(HR)
MYB: 102258695(HR)
MYD: 102755445(HR)
MNA: 107543545(HR)
HAI: 109382348(HR)
DRO: 112305232(HR)
PALE: 102895975(HR)
RAY: 107509236(HR)
MJV: 108393188(HR)
LAV: 100675014(HR)
TMU: 101357906
MDO: 100033094(HR)
SHR: 100913734(HR)
PCW: 110200432(HR)
OAA: 100088813(HR)
GGA: 107049623(HR)
TGU: 115498188(HR)
LSR: 110479416(HR)
SCAN: 108963604
PHI: 102114626(HR)
PMAJ: 107213805(HR)
FPG: 101919240(HR)
FCH: 102050963(HR)
CLV: 102095540(HR)
NNI: 104016037
ASN: 102375877(HR)
AMJ: 102561002(HR)
CMY: 102938050(HR)
CPIC: 101944418(HR)
 » show all
Reference
  Authors
Liu L, Kim H, Casta A, Kobayashi Y, Shapiro LS, Christiano AM
  Title
Hairless is a histone H3K9 demethylase.
  Journal
FASEB J 28:1534-42 (2014)
DOI:10.1096/fj.13-237677
  Sequence
[hsa:55806]
LinkDB

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