KEGG   ORTHOLOGY: K00522
Entry
K00522                      KO                                     

Name
FTH1
Definition
ferritin heavy chain [EC:1.16.3.2]
Pathway
ko04216  Ferroptosis
ko04217  Necroptosis
ko04978  Mineral absorption
Disease
H00211  Hemochromatosis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09140 Cellular Processes
  09143 Cell growth and death
   04216 Ferroptosis
    K00522  FTH1; ferritin heavy chain
   04217 Necroptosis
    K00522  FTH1; ferritin heavy chain
 09150 Organismal Systems
  09154 Digestive system
   04978 Mineral absorption
    K00522  FTH1; ferritin heavy chain
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome
    K00522  FTH1; ferritin heavy chain
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.16  Oxidizing metal ions
   1.16.3  With oxygen as acceptor
    1.16.3.2  bacterial non-heme ferritin
     K00522  FTH1; ferritin heavy chain
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   K00522  FTH1; ferritin heavy chain
  Exosomal proteins of bladder cancer cells
   K00522  FTH1; ferritin heavy chain
Genes
HSA: 2495(FTH1)
PTR: 104005653 473551(FTHL17) 738986(FTH1)
PPS: 100979329(FTH1) 100992304
GGO: 101139119(FTH1) 101147863
PON: 100173063(FTH1) 100435152 100442351 100447799(FTHL17)
NLE: 100598158(FTH1)
MCC: 574118(FTH1) 699053 707011 707851(FTHL17) 714576
MCF: 101926130(FTH1) 102146520
CSAB: 103226189 103241960(FTH1)
RRO: 104665915 104667685 104671809 104679370(FTH1)
SBQ: 101029833 101031817(FTH1)
MMU: 14319(Fth1)
MCAL: 110285677(Fth1) 110287058(Fth1p18) 110287929
MPAH: 110314735 110327990(Fth1)
RNO: 25319(Fth1) 679217 689130
MUN: 110544339 110548076(Fth1)
HGL: 101723628(Fth1) 106007745
CCAN: 109682913 109700913(Fth1)
OCU: 100009597(FTH1)
TUP: 102467785(FTH1) 102493282
CFA: 100499480(FTH1) 403631(FTH1)
VVP: 112911077(FTH1)
AML: 100470967(FTH1)
UMR: 103673242 103678175(FTH1)
UAH: 113246990(FTH1) 113250385
ELK: 111149509
FCA: 101080615 654516(FTH1)
PTG: 102951417(FTHL17) 102951898(FTH1)
PPAD: 109246565(FTH1) 109249338(FTHL17) 109261932
AJU: 106983516(FTHL17) 106986975(FTH1)
BTA: 100300003 281173(FTH1)
BIU: 109554491(FTH1)
SSC: 397030(FTH1)
BACU: 102999703(FTH1) 103012179
OOR: 101277313(FTH1)
DLE: 111183880(FTH1)
PCAD: 102977739(FTH1)
MNA: 107527641(FTH1) 107540068
HAI: 109390045(FTH1)
PALE: 102886235(FTH1) 102887940
RAY: 107501607(FTH1) 107503923(FTH1P18) 107505665
MJV: 108384127(FTHL17) 108407764(FTH1)
SHR: 100921504(FTHL17) 116419734(FTH1)
GGA: 395970(FTH1)
MGP: 100550283(FTH1)
CJO: 107314460(FTH1)
NMEL: 110401443(FTH1)
APLA: 101798267
TGU: 100190515(FTH1)
LSR: 110481429 110484929(FTH1)
SCAN: 103822126(FTH1)
GFR: 102040223(FTH1)
FAB: 101810471(FTH1)
PHI: 102106212(FTL) 102112207(FTH1)
PMAJ: 107199045 107205408(FTH1)
CCAE: 111930410(FTH1) 111943644
CCW: 104697642(FTH1)
ETL: 114067857(FTH1) 114072656
FPG: 101910956(FTH1)
FCH: 102058424(FTH1)
CLV: 102097301(FTH1)
EGZ: 104129641(FTH1)
NNI: 104009481(FTH1) 104011616
ACUN: 113481284(FTH1)
PADL: 103925789(FTH1)
AAM: 106490041(FTH1)
XLA: 100036818 100036823 108706145 379267(fth1.S) 379339 379618(MGC68606) 398724(ftmt.S) 399281(fth1.L) 444042 779108(fth1a)
XTR: 394604(fth1.1) 394709(MGC76132) 394820(MGC75752) 448524 448718(ftmt)
DRE: 100006428 100006523(fthl28) 100126128(zgc:173594) 100170833(fthl29) 406286(zgc:56095) 436651(fthl27) 447823(fth1b) 553552(fthl31) 558816 559768(fthl30) 58108(fth1a)
CIN: 100175623
SPU: 100892337
DME: Dmel_CG2216(Fer1HCH) Dmel_CG4349(Fer3HCH)
DSI: Dsimw501_GD15908(Dsim_GD15908) Dsimw501_GD17157(Dsim_GD17157)
DYA: Dyak_GE16178 Dyak_GE23394(Dyak_Fer1HCH)
MDE: 101898530
OBB: 114871271
NVI: 100116376(Ft)
CSOL: 105361464
BMOR: 732916 732949
API: 100168726
DNX: 107173194
AGS: 114127725
RMD: 113555523
ZNE: 110832915
CEL: CELE_C54F6.14(ftn-1) CELE_D1037.3(ftn-2)
CBR: CBG00826(Cbr-ftn-1) CBG12026(Cbr-ftn-2)
EGL: EGR_09055
AMIL: 114954346
PDAM: 113666209
ATH: AT2G40300(FER4) AT3G11050(FER2) AT3G56090(FER3) AT5G01600(FER1)
GMX: 100778273 100781581 100787160(FER2-1) 100799326 100810000 547476(SFERH-3) 547477(SFERH-4) 547698 547824(H-1) 547988(SFERH-2)
LJA: Lj2g3v2817760.1(Lj2g3v2817760.1)
CSV: 101221012
CMO: 103495136
MCHA: 111015964
DOSA: Os11t0106700-01(Os11g0106700) Os12t0106000-01(Os12g0106000)
BDI: 100837024
ATS: 109758981(LOC109758981) 109769587(LOC109769587)
ZMA: 542392(fer2) 542553(fer1)
ATR: 18433372
CRE: CHLREDRAFT_206372(FER1)
APRO: F751_1166
MIS: MICPUN_96750(FTN)
SMIN: v1.2.000231.t1(symbB.v1.2.000231.t1)
 » show all
Reference
PMID:8695634
  Authors
Harrison PM, Arosio P
  Title
The ferritins: molecular properties, iron storage function and cellular regulation.
  Journal
Biochim Biophys Acta 1275:161-203 (1996)
DOI:10.1016/0005-2728(96)00022-9
Reference
PMID:3840162
  Authors
Boyd D, Vecoli C, Belcher DM, Jain SK, Drysdale JW
  Title
Structural and functional relationships of human ferritin H and L chains deduced from cDNA clones.
  Journal
J Biol Chem 260:11755-61 (1985)
  Sequence
[hsa:2495]
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