KEGG   ORTHOLOGY: K00559
Entry
K00559                      KO                                     
Symbol
SMT1, ERG6
Name
sterol 24-C-methyltransferase [EC:2.1.1.41]
Pathway
map00100  Steroid biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00102  Ergocalciferol biosynthesis, squalene 2,3-epoxide => ergosterol/ergocalciferol
M00917  Phytosterol biosynthesis, squalene 2,3-epoxide => campesterol/sitosterol
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09103 Lipid metabolism
   00100 Steroid biosynthesis
    K00559  SMT1, ERG6; sterol 24-C-methyltransferase
Enzymes [BR:ko01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.41  sterol 24-C-methyltransferase
     K00559  SMT1, ERG6; sterol 24-C-methyltransferase
Other DBs
RN: R04427 R07481
COG: COG0500
GO: 0003838
Genes
BMY: BM_BM4647(Bma-strm-1)
NAI: NECAME_03546
AQU: 100639491
ATH: AT5G13710(SMT1)
ALY: 9307650
CRB: 17882375
CSAT: 104705624 104735382 104769590
EUS: EUTSA_v10014014mg
BRP: 103850891 103856028
BNA: 106371823 106384356 106392091 106431054 106440921
CPAP: 110809321
CIT: 102628258
GRA: 105790583
GAB: 108470188
VRA: 106760797
VAR: 108332339
VUN: 114165537
CAM: 101497864
LJA: Lj3g3v0825030.1(Lj3g3v0825030.1) Lj3g3v0825030.2(Lj3g3v0825030.2)
FVE: 101293342
RCN: 112181939
PPER: 18785581
PMUM: 103330640
PAVI: 110765835
PDUL: 117619806
JCU: 105628730
SIND: 105169293
EGT: 105969542
ECAD: 122595873
CCAV: 112522572
BVG: 104907757
SOE: 110778345
NNU: 104597375
NCOL: 116249160
DOSA: Os03t0807600-00(Os03g0807600) Os07t0206700-01(Os07g0206700) Os11t0296900-00(Os11g0296900)
OBR: 102713236
TUA: 125529735
AOF: 109833715
SMO: SELMODRAFT_449609(SMT1-2) SELMODRAFT_449613(SMT1-1)
PPP: 112291818
MIS: MICPUN_93596(SMT1)
SCE: YML008C(ERG6)
SEUB: DI49_4081
ERC: Ecym_4063
KMX: KLMA_30671(ERG6)
NCS: NCAS_0H02570(NCAS0H02570)
NDI: NDAI_0C01050(NDAI0C01050)
TPF: TPHA_0D02350(TPHA0D02350)
TBL: TBLA_0D01630(TBLA0D01630)
TDL: TDEL_0A03930(TDEL0A03930)
KAF: KAFR_0C05410(KAFR0C05410)
KNG: KNAG_0B03670(KNAG0B03670)
CAL: CAALFM_C302150CA(ERG6)
CDU: CD36_82130(ERG6)
SLB: AWJ20_2170(ERG6)
BNN: FOA43_002150(ERG6)
BBRX: BRETT_003844(ERG6)
NCR: NCU02502 NCU03006(erg-4)
NTE: NEUTE1DRAFT150553(NEUTE1DRAFT_150553) NEUTE1DRAFT73978(NEUTE1DRAFT_73978)
ANG: ANI_1_1324144(An16g00300) ANI_1_256124(An14g01590) ANI_1_752184(An04g04210)
APUU: APUU_21581S APUU_22198S(ERG6_1) APUU_80754S(ERG6_2)
PTE: PTT_11273
SPO: SPBC16E9.05(erg6)
CNE: CNB03100
CNB: CNBB2600
TASA: A1Q1_06727
LBC: LACBIDRAFT_184995(erg6)
ABP: AGABI1DRAFT115299(AGABI1DRAFT_115299)
ABV: AGABI2DRAFT194260(AGABI2DRAFT_194260)
MGL: MGL_2877
MRT: MRET_3473
DDI: DDB_G0288907(smt1)
DFA: DFA_09943(smt1)
SMIN: v1.2.010320.t1(symbB.v1.2.010320.t1) v1.2.020967.t1(symbB.v1.2.020967.t1) v1.2.040208.t1(symbB.v1.2.040208.t1)
SPAR: SPRG_05001
LPAN: LPMP_352450(LMSMT)
TMC: LMI_2904
NDK: I601_4050(rebM_4)
SUS: Acid_3267
 » show all
Reference
  Authors
Jayasimha P, Nes WD
  Title
Photoaffinity labeling and mutational analysis of 24-C-sterol methyltransferase defines the AdoMet binding site.
  Journal
Lipids 43:681-93 (2008)
DOI:10.1007/s11745-008-3198-x
  Sequence
[sce:YML008C]
Reference
  Authors
Ganapathy K, Kanagasabai R, Nguyen TT, Nes WD
  Title
Purification, characterization and inhibition of sterol C24-methyltransferase from Candida albicans.
  Journal
Arch Biochem Biophys 505:194-201 (2011)
DOI:10.1016/j.abb.2010.10.008
  Sequence
Reference
  Authors
Diener AC, Li H, Zhou W, Whoriskey WJ, Nes WD, Fink GR
  Title
Sterol methyltransferase 1 controls the level of cholesterol in plants.
  Journal
Plant Cell 12:853-70 (2000)
DOI:10.1105/tpc.12.6.853
  Sequence
[ath:AT5G13710]
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