KEGG   ORTHOLOGY: K01231
Entry
K01231                      KO                                     

Name
MAN2
Definition
alpha-mannosidase II [EC:3.2.1.114]
Pathway
ko00510  N-Glycan biosynthesis
ko00513  Various types of N-glycan biosynthesis
ko01100  Metabolic pathways
Module
M00075  N-glycan biosynthesis, complex type
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00510 N-Glycan biosynthesis
    K01231  MAN2; alpha-mannosidase II
   00513 Various types of N-glycan biosynthesis
    K01231  MAN2; alpha-mannosidase II
Enzymes [BR:ko01000]
 3. Hydrolases
  3.2  Glycosylases
   3.2.1  Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
    3.2.1.114  mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase
     K01231  MAN2; alpha-mannosidase II
Other DBs
RN: R05984
GO: 0004572
Genes
HSA: 4122(MAN2A2) 4124(MAN2A1)
PTR: 461982(MAN2A1) 745986(MAN2A2)
PPS: 100973826(MAN2A1) 100975142(MAN2A2)
GGO: 101130735(MAN2A2) 101130746(MAN2A1)
PON: 100449341(MAN2A2) 100455258(MAN2A1)
NLE: 100581120(MAN2A1) 100598002(MAN2A2)
MCC: 705480(MAN2A1) 715720(MAN2A2)
MCF: 101865831(MAN2A1) 102118107(MAN2A2)
CSAB: 103231182(MAN2A2) 103244316(MAN2A1)
RRO: 104675604(MAN2A1) 104679282(MAN2A2)
RBB: 108517212(MAN2A2)
CJC: 100394604(MAN2A2) 100415670(MAN2A1)
SBQ: 101028436(MAN2A1) 101032034(MAN2A2)
MMU: 140481(Man2a2) 17158(Man2a1)
MCAL: 110298418(Man2a2) 110302683 110312160(Man2a1)
MPAH: 110327713(Man2a2) 110335524(Man2a1)
RNO: 25478(Man2a1) 308757(Man2a2)
CGE: 100757006(Man2a1) 100764014(Man2a2)
NGI: 103749886(Man2a2) 103752287(Man2a1)
HGL: 101697315(Man2a1) 101717094(Man2a2)
CCAN: 109695085(Man2a2) 109699084(Man2a1)
OCU: 100345634(MAN2A2) 100350334(MAN2A1)
TUP: 102469872(MAN2A2) 102485972(MAN2A1)
CFA: 488745(MAN2A2) 488878(MAN2A1)
VVP: 112915442(MAN2A1) 112921479(MAN2A2)
AML: 100474640(MAN2A1) 100475150(MAN2A2)
UMR: 103660265(MAN2A2) 103675784(MAN2A1)
UAH: 113255007(MAN2A1) 113263716(MAN2A2)
ORO: 101368244(MAN2A1) 101371875(MAN2A2)
FCA: 101086451(MAN2A1) 101101317(MAN2A2)
PTG: 102953845(MAN2A1) 102959757(MAN2A2)
PPAD: 109267616(MAN2A1) 109273465(MAN2A2)
AJU: 106965940(MAN2A2) 106975671(MAN2A1)
BTA: 521539(MAN2A1) 527449(MAN2A2)
BOM: 102269911(MAN2A2) 102286530(MAN2A1)
BIU: 109562380(MAN2A1) 109575464(MAN2A2)
BBUB: 102393495(MAN2A2) 102396245(MAN2A1)
CHX: 102171012(MAN2A2) 102182591(MAN2A1)
OAS: 101106798(MAN2A2) 101116572(MAN2A1)
SSC: 100154397(MAN2A2) 100514631(MAN2A1)
CFR: 102512093(MAN2A2) 102513706(MAN2A1)
CDK: 105094696(MAN2A2) 105095392(MAN2A1)
BACU: 103020657(MAN2A1) 103021128(MAN2A2)
LVE: 103074675(MAN2A2) 103076739(MAN2A1)
OOR: 101272169(MAN2A1) 101272204(MAN2A2)
DLE: 111169626(MAN2A2) 111183761(MAN2A1)
PCAD: 102974194(MAN2A2) 102974411(MAN2A1)
ECB: 100053432(MAN2A2) 100064575(MAN2A1)
EPZ: 103546211(MAN2A2) 103551677(MAN2A1)
EAI: 106832048(MAN2A2) 106832412(MAN2A1)
MYB: 102239755(MAN2A2) 102241544(MAN2A1)
MYD: 102760778(MAN2A1) 102764752(MAN2A2)
MNA: 107540397(MAN2A2) 107546496(MAN2A1)
HAI: 109371540(MAN2A1) 109381472(MAN2A2)
DRO: 112305889(MAN2A2) 112307206(MAN2A1)
PALE: 102878318(MAN2A1) 102884371(MAN2A2)
RAY: 107506530(MAN2A1) 107514130(MAN2A2)
MJV: 108385796(MAN2A2) 108407113(MAN2A1)
LAV: 100669338(MAN2A1) 100671385(MAN2A2)
MDO: 100010442(MAN2A1) 100014504(MAN2A2)
SHR: 100913308(MAN2A1) 100922248(MAN2A2)
PCW: 110193635(MAN2A2) 110195899(MAN2A1)
OAA: 100082559(MAN2A1) 100090754(MAN2A2)
GGA: 415585(MAN2A2) 415611(MAN2A1)
MGP: 100539000(MAN2A2) 104915174(MAN2A1)
CJO: 107306350(MAN2A1) 107318993(MAN2A2)
NMEL: 110389397(MAN2A1) 110403851(MAN2A2)
APLA: 101790343(MAN2A2) 101792614(MAN2A1)
ACYG: 106042345(MAN2A1) 106048641(MAN2A2)
TGU: 100226019(MAN2A2) 100227845(MAN2A1)
LSR: 110467593(MAN2A1) 110476670(MAN2A2)
SCAN: 103816135(MAN2A2) 103824196(MAN2A1)
GFR: 102041186(MAN2A1) 102041635(MAN2A2)
FAB: 101806895(MAN2A2) 101819402(MAN2A1)
PHI: 102101154(MAN2A2) 102113458(MAN2A1)
PMAJ: 107209587(MAN2A2) 107216400(MAN2A1)
CCAE: 111940865(MAN2A1) 111943021(MAN2A2)
CCW: 104683853(MAN2A2) 104693206(MAN2A1)
ETL: 114056033(MAN2A1) 114064253(MAN2A2)
FPG: 101913159(MAN2A2) 101921020
FCH: 102048168(MAN2A2) 102050767(MAN2A1)
CLV: 102090971(MAN2A2) 102097702(MAN2A1)
EGZ: 104133484(MAN2A2) 104135037(MAN2A1)
NNI: 104017021(MAN2A2) 104022201(MAN2A1)
ACUN: 113484037(MAN2A2) 113489918(MAN2A1)
PADL: 103914784(MAN2A2) 103920875(MAN2A1)
AAM: 106491449(MAN2A2)
ASN: 102369470(MAN2A1) 102383379(MAN2A2)
AMJ: 102561641(MAN2A1) 102566705(MAN2A2)
PSS: 102459905(MAN2A1)
CMY: 102941559(MAN2A2) 102944199(MAN2A1)
CPIC: 101937670(MAN2A1) 101953630(MAN2A2)
ACS: 100555933(man2a1) 100568077(man2a2)
PVT: 110072017(MAN2A1) 110084439(MAN2A2)
PBI: 103053695(MAN2A1) 103058391(MAN2A2)
PMUR: 107289784(MAN2A2) 107293675(MAN2A1)
TSR: 106543694(MAN2A1) 106553803(MAN2A2)
PMUA: 114584355(MAN2A2) 114606107(MAN2A1)
GJA: 107120457(MAN2A1) 107125467(MAN2A2)
XLA: 108707218(man2a1.S) 108712863(man2a2.S) 108717353(man2a1.L) 443991(man2a2.L)
XTR: 100036612(man2a1) 448465(man2a2)
NPR: 108789334(MAN2A1) 108798147(MAN2A2)
DRE: 100333987(man2a2) 560219(man2a1)
SANH: 107663767 107670215 107673231(man2a2) 107691725(man2a1)
CCAR: 109078545
IPU: 108274717(man2a2)
PHYP: 113529699(man2a2)
AMEX: 103023301(man2a1) 103041860(man2a2)
EEE: 113572463 113588518(man2a2)
TRU: 101061792(man2a2) 101077627(man2a1)
LCO: 104925267(man2a2) 104932414
NCC: 104944004(man2a2)
MZE: 101474154 101483319(man2a2)
ONL: 100708597(man2a2) 102081444
OLA: 101158104(man2a2) 101174073
XMA: 102218498(man2a1) 102232197(man2a2)
XCO: 114136954 114155110(man2a2)
PRET: 103460455(man2a1) 103466353(man2a2)
CVG: 107098036(man2a1) 107104235(man2a2)
NFU: 107374983(man2a1) 107388979(man2a2)
KMR: 108228395 108239965(man2a2)
ALIM: 106515631(man2a2) 106536243
AOCE: 111563148(man2a2) 111564348
CSEM: 103380513(man2a2) 103390365(man2a1)
POV: 109624583(man2a2) 109642276
LCF: 108874626(man2a1) 108875305(man2a2)
SDU: 111228707(man2a2) 111238819(man2a1)
SLAL: 111651803 111655358(man2a2)
HCQ: 109530362(man2a2)
BPEC: 110153167 110165893(man2a2)
MALB: 109968742(man2a2) 109973112(man2a1)
SASA: 106561301 106562091(man2a1) 106568341 106573342(man2a2)
SALP: 111952337(man2a2) 111961325(man2a1) 111962448 111981710
ELS: 105018384(man2a2) 105027936(man2a1)
SFM: 108932015(man2a1) 108941123(man2a2)
PKI: 111835779(man2a1) 111845078(man2a2)
LCM: 102355620 102360088(MAN2A2)
CMK: 103178412(man2a1) 103188552(man2a2)
BFO: 118411916
CIN: 100180083
SPU: 594620
APLC: 110979321
SKO: 102802038
DME: Dmel_CG18802(alpha-Man-IIa)
DER: 6552301
DSE: 6607114
DSI: Dsimw501_GD18615(Dsim_GD18615)
DAN: 6500000
DSR: 110191164
DPE: 6595142
DMN: 108155782
DWI: 6647583
DAZ: 108614123
DNV: 108653307
DHE: 111593673
DVI: 6629947
MDE: 101898268
LCQ: 111685869
AAG: 5575653
AME: 552382
BIM: 100749601
BTER: 100646824
CCAL: 108623658
OBB: 114880562
SOC: 105198479
MPHA: 105836778
AEC: 105154407
ACEP: 105623777
PBAR: 105423365
VEM: 105565777
HST: 105190974
DQU: 106750368
CFO: 105253605
LHU: 105674564
PGC: 109851679
OBO: 105274664
PCF: 106789840
NVI: 100116564
CSOL: 105364669
TCA: 660728
DPA: 109544976
ATD: 109605290
NVL: 108562674
BMOR: 101742043
BMAN: 114250890
PMAC: 106721685
PRAP: 110993078
HAW: 110380432
TNL: 113499077
PXY: 105380392
API: 100169064
DNX: 107161638
AGS: 114131656
RMD: 113555742
BTAB: 109044339
CLEC: 106666206
ZNE: 110835247
FCD: 110848037
PVM: 113815567
TUT: 107360206
DPTE: 113797886
PTEP: 107455528
CEL: CELE_F58H1.1(aman-2)
CBR: CBG23330(Cbr-aman-2)
TSP: Tsp_10745
SHX: MS3_01222
EGL: EGR_08871
NVE: 5512609
EPA: 110234138
ADF: 107347367
AMIL: 114961754
PDAM: 113670726
SPIS: 111324658
DGT: 114525319
ATH: AT5G14950(GMII)
ALY: 9309767
CRB: 17881567
THJ: 104821170
CIT: 102615196
TCC: 18601342
EGR: 104422581
VRA: 106770832
VAR: 108345656
VUN: 114180334
CCAJ: 109817438
CAM: 101499632(MAN2A2)
LJA: Lj2g3v1022240.1(Lj2g3v1022240.1)
ADU: 107471073
AIP: 107622688
FVE: 101296768
RCN: 112184196
PPER: 18782416
PMUM: 103329931
PAVI: 110756683
PXB: 103928463
ZJU: 107415425
CSV: 101208332
CMO: 103487047
MCHA: 111018346
RCU: 8280600
JCU: 105642251
MESC: 110601253
JRE: 108992841
QSU: 111999605
VVI: 100243903(MAN2A2)
SLY: 101266287
SPEN: 107011510
SOT: 102605224
CANN: 107860595
NSY: 104211404
NTO: 104108022
NAU: 109205422
SIND: 105177181
OEU: 111409226
HAN: 110903921
LSV: 111891915
CCAV: 112523600
DCR: 108214457
BVG: 104905356
SOE: 110786831
NNU: 104607979
OSA: 4340636
DOSA: Os06t0245700-00(Os06g0245700)
OBR: 102707404
BDI: 100822520
ATS: 109783252
SBI: 8061493
SITA: 101761357
PDA: 103710003
MUS: 103990861
DCT: 110092430
PEQ: 110026121
AOF: 109820905
ATR: 18446724
PPP: 112275693
DFA: DFA_02000 DFA_07693(manD)
 » show all
Reference
PMID:8524845
  Authors
Misago M, Liao YF, Kudo S, Eto S, Mattei MG, Moremen KW, Fukuda MN
  Title
Molecular cloning and expression of cDNAs encoding human alpha-mannosidase II and a previously unrecognized alpha-mannosidase IIx isozyme.
  Journal
Proc Natl Acad Sci U S A 92:11766-70 (1995)
DOI:10.1073/pnas.92.25.11766
  Sequence
[hsa:4124 4122]
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