KEGG   ORTHOLOGY: K01320
Entry
K01320                      KO                                     

Name
F7
Definition
coagulation factor VII [EC:3.4.21.21]
Pathway
ko04610  Complement and coagulation cascades
Disease
H02256  Factor VII deficiency
Brite
KEGG Orthology (KO) [BR:ko00001]
 09150 Organismal Systems
  09151 Immune system
   04610 Complement and coagulation cascades
    K01320  F7; coagulation factor VII
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors
    K01320  F7; coagulation factor VII
Enzymes [BR:ko01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.21  Serine endopeptidases
    3.4.21.21  coagulation factor VIIa
     K01320  F7; coagulation factor VII
Peptidases and inhibitors [BR:ko01002]
 Serine peptidases
  Family S1: chymotrypsin family
   K01320  F7; coagulation factor VII
Genes
HSA: 2155(F7)
PTR: 744785(F7)
PPS: 100987335(F7)
GGO: 101136216(F7)
PON: 100452636(F7)
NLE: 100607316(F7)
MCC: 721933(F7)
MCF: 102121077(F7)
CSAB: 103214833(F7)
RRO: 104659908(F7)
RBB: 108521813(F7)
CJC: 100410381(F7)
SBQ: 101043113(F7)
MMU: 14068(F7)
MCAL: 110300360(F7)
MPAH: 110336954(F7)
RNO: 260320(F7)
CGE: 100758763(F10)
NGI: 103746283(F7)
HGL: 101706917(F7)
CCAN: 109686462(F7)
OCU: 100009399(F7)
TUP: 102482034(F7)
CFA: 607661(F7)
VVP: 112927508(F7)
AML: 100471728(F7)
UMR: 103657528(F7)
UAH: 113247584(F7)
ORO: 101366144(F7)
ELK: 111147145
FCA: 101090581(F7)
PTG: 102950134(F7)
PPAD: 109264041(F7)
AJU: 106986724(F7)
BTA: 617960(F7)
BOM: 102272114(F7)
BIU: 109567023(F7)
BBUB: 102408637(F7)
CHX: 102174404(F7)
OAS: 101118369(F7)
SSC: 733661(F7)
CFR: 102519118(F7)
CDK: 105091336(F7)
LVE: 103076497(F7)
OOR: 101277688(F7)
DLE: 111176366(F7)
PCAD: 102977949(F7)
ECB: 100067072(F7)
EPZ: 103549658(F7)
EAI: 106839877(F7)
MYB: 102260786(F7)
MYD: 102765822(F7)
MNA: 107536944(F7)
HAI: 109383930(F7)
DRO: 112321523(F7)
PALE: 102884062(F7)
RAY: 107514334(F7)
MJV: 108398704(F7)
LAV: 100655748(F7)
TMU: 101347612
MDO: 100022420(F7)
SHR: 100921248(F7)
PCW: 110193401(F7)
GGA: 395086(F7)
MGP: 100548839(F7)
CJO: 107307824(F7)
NMEL: 110407377
APLA: 101796107(F7)
ACYG: 106046420
TGU: 100223776
LSR: 110478744
SCAN: 103812401
GFR: 102035674(F7)
FAB: 101814835(F7)
PHI: 102113790(F7)
PMAJ: 107211187(F7)
CCW: 104686114(F7)
ETL: 114057854
FPG: 101911545(F7)
FCH: 102049587(F7)
CLV: 102092108(F7)
EGZ: 104132450(F7)
NNI: 104019371(F7)
ACUN: 113485847(F7)
PADL: 103918860(F7)
AAM: 106493960(F7)
ASN: 102375756(F7)
AMJ: 102560637(F7)
PSS: 102463876(F7)
CMY: 102939588(F7)
CPIC: 101936681(F7)
ACS: 107982633
PBI: 103068222
PMUR: 107290448(F7)
PMUA: 114596455(F7)
GJA: 107110910
XLA: 444394(f7.S)
XTR: 780280(f7)
NPR: 108791687(F7)
DRE: 100038778(f7l) 114423(f7)
LCO: 104936792
XMA: 102224608
LCF: 108877177
ELS: 105019751
LCM: 102350380(F7)
CMK: 103183473
 » show all
Reference
  Authors
Suzuki K, Sugawara T, Ishida Y, Suwabe A
  Title
Compound heterozygous mutations (p.Leu13Pro and p.Tyr294*) associated with factor VII deficiency cause impaired secretion through ineffective translocation and extensive intracellular degradation of factor VII.
  Journal
Thromb Res 131:166-72 (2013)
DOI:10.1016/j.thromres.2012.10.005
Reference
PMID:3486420
  Authors
Hagen FS, Gray CL, O'Hara P, Grant FJ, Saari GC, Woodbury RG, Hart CE, Insley M, Kisiel W, Kurachi K, et al.
  Title
Characterization of a cDNA coding for human factor VII.
  Journal
Proc Natl Acad Sci U S A 83:2412-6 (1986)
DOI:10.1073/pnas.83.8.2412
  Sequence
[hsa:2155]
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