KEGG   ORTHOLOGY: K01325
Entry
K01325                      KO                                     

Name
KLK1_2
Definition
tissue kallikrein [EC:3.4.21.35]
Pathway
ko04614  Renin-angiotensin system
ko04961  Endocrine and other factor-regulated calcium reabsorption
Brite
KEGG Orthology (KO) [BR:ko00001]
 09150 Organismal Systems
  09152 Endocrine system
   04614 Renin-angiotensin system
    K01325  KLK1_2; tissue kallikrein
  09155 Excretory system
   04961 Endocrine and other factor-regulated calcium reabsorption
    K01325  KLK1_2; tissue kallikrein
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors
    K01325  KLK1_2; tissue kallikrein
  09183 Protein families: signaling and cellular processes
   04147 Exosome
    K01325  KLK1_2; tissue kallikrein
Enzymes [BR:ko01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.21  Serine endopeptidases
    3.4.21.35  tissue kallikrein
     K01325  KLK1_2; tissue kallikrein
Peptidases and inhibitors [BR:ko01002]
 Serine peptidases
  Family S1: chymotrypsin family
   K01325  KLK1_2; tissue kallikrein
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   K01325  KLK1_2; tissue kallikrein
Genes
HSA: 3816(KLK1) 3817(KLK2)
PTR: 107969791(KLK1) 748637(KLK2)
PPS: 100967412(KLK2) 100995152(KLK1)
GGO: 101144843(KLK1)
PON: 100431610(KLK1) 100432729(KLK2)
NLE: 115836983(KLK1)
MCC: 106994826(KLK1) 719436
MCF: 102135781(KLK1) 102139474(KLK2)
CSAB: 103235100(KLK1) 103235106(KLK2)
RRO: 104667242(KLK1)
RBB: 108532416(KLK1)
CJC: 100402463(KLK1)
SBQ: 101045013(KLK1) 101045648
MMU: 13646(Klk1b22) 13648(Klk1b9) 16612(Klk1) 16613(Klk1b11) 16616(Klk1b21) 16617(Klk1b24) 16618(Klk1b26) 16619(Klk1b27) 16622(Klk1b5) 16623(Klk1b1) 16624(Klk1b8) 18050(Klk1b3)
RNO: 100361452(Klk1c4) 100911689 103690048 108348116 24523(Klk1) 24594(Klk1b3) 24841(Klk1c2) 292855(Klk1c12) 292858(Klk1c10) 292866(Klk1c8) 292868(Klk1c9) 292872(Klk1c3) 408242(Klk1c6)
CGE: 100754155
NGI: 103743763(Klk1) 103743764
HGL: 101705888 101719001(Klk1)
OCU: 100101620
TUP: 102489025(KLK1)
CFA: 403942(KLK1) 403967(KLK2)
AML: 100476682 100476932(KLK1)
UAH: 113247288(KLK1) 113247344
FCA: 101090062(KLK1) 101097936
PTG: 102963319(KLK1) 102963589
PPAD: 109252991 109252996(KLK1)
AJU: 106989422(KLK1)
BTA: 493738(KLK1)
BOM: 102283027(KLK1)
BIU: 109571921(KLK1)
BBUB: 102406481
CHX: 102177186(KLK1)
OAS: 100048991(KLK1)
SSC: 431673(KLK1)
CFR: 102515972(KLK1)
CDK: 105100157(KLK1)
BACU: 103007165(KLK1)
LVE: 103081797(KLK1)
OOR: 101283477(KLK1)
DLE: 111181109(KLK1)
PCAD: 102980618(KLK1)
EAI: 106845317 106845494(KLK1)
MYB: 102251175(KLK1)
MYD: 102765308(KLK1)
MNA: 107531831(KLK1)
HAI: 109390988(KLK1)
DRO: 112310143(KLK1)
PALE: 102893946(KLK1) 102898477
RAY: 107500469(KLK1)
MJV: 108397931(KLK1)
TMU: 101344800
OAA: 100087855(KLK1)
PRET: 103465468
 » show all
Reference
  Authors
Gkika D, Topala CN, Chang Q, Picard N, Thebault S, Houillier P, Hoenderop JG, Bindels RJ
  Title
Tissue kallikrein stimulates Ca(2+) reabsorption via PKC-dependent plasma membrane accumulation of TRPV5.
  Journal
EMBO J 25:4707-16 (2006)
DOI:10.1038/sj.emboj.7601357
  Sequence
[mmu:16612]
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