KEGG   ORTHOLOGY: K01334
Entry
K01334                      KO                                     

Name
CFD
Definition
complement factor D [EC:3.4.21.46]
Pathway
ko04610  Complement and coagulation cascades
ko05150  Staphylococcus aureus infection
ko05171  Coronavirus disease - COVID-19
Disease
H00104  Alternative complement pathway component defects
Brite
KEGG Orthology (KO) [BR:ko00001]
 09150 Organismal Systems
  09151 Immune system
   04610 Complement and coagulation cascades
    K01334  CFD; complement factor D
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05150 Staphylococcus aureus infection
    K01334  CFD; complement factor D
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    K01334  CFD; complement factor D
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors
    K01334  CFD; complement factor D
Enzymes [BR:ko01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.21  Serine endopeptidases
    3.4.21.46  complement factor D
     K01334  CFD; complement factor D
Peptidases and inhibitors [BR:ko01002]
 Serine peptidases
  Family S1: chymotrypsin family
   K01334  CFD; complement factor D
Genes
HSA: 1675(CFD)
PPS: 100968920(CFD)
PON: 100936423(CFD)
NLE: 100599422(CFD)
MCC: 721138(CFD)
MCF: 102136571(CFD)
CSAB: 103233571(CFD)
RRO: 104671463(CFD)
CJC: 100389630(CFD)
SBQ: 101030841(CFD)
MMU: 11537(Cfd)
MCAL: 110303909(Cfd)
MPAH: 110326960(Cfd)
RNO: 54249(Cfd)
MUN: 110551364(Cfd)
CGE: 100763302(Cfd)
NGI: 103737401(Cfd)
HGL: 106007830(Cfd)
CCAN: 109693669(Cfd)
TUP: 106734227(CFD)
CFA: 485095(CFD)
VVP: 112935509(CFD)
AML: 100483447(CFD)
UAH: 113242706(CFD)
ORO: 101380360(CFD)
ELK: 111161686
FCA: 101093500(CFD)
PPAD: 109257710(CFD)
AJU: 113596379
BTA: 505647(CFD)
BOM: 102275200(CFD)
BBUB: 102411586(CFD)
CHX: 102173560(CFD)
OAS: 101115705(CFD)
SSC: 396877(CFD)
CFR: 102507253(CFD)
CDK: 105106574(CFD)
LVE: 103086658(CFD)
OOR: 101272668(CFD)
DLE: 111170499(CFD)
PCAD: 102995550(CFD)
ECB: 111774154(CFD)
EAI: 106834238(CFD)
MYD: 102756294(CFD)
MNA: 107538545(CFD)
HAI: 109390585(CFD)
PALE: 102897797(CFD)
RAY: 107500957(CFD)
MJV: 108395527(CFD)
LAV: 100672291(CFD)
TMU: 101356637
SHR: 100928352(CFD)
PCW: 110196242(CFD)
OAA: 791100(CFD)
GGA: 100857593(CFD)
MGP: 100541228(CFD)
CJO: 107325464(CFD)
NMEL: 110388819(CFD)
APLA: 113845674
TGU: 100224290
LSR: 110475732
SCAN: 103822039
GFR: 102036496(CFD)
FAB: 101807799(CFD)
PHI: 102114080(CFD)
PMAJ: 107215597
CCAE: 111940403
ETL: 114066373(CFD)
FPG: 101921526(CFD)
FCH: 102048162(CFD)
CLV: 106145861(CFD)
NNI: 104016308(CFD)
AAM: 106484250(CFD)
ASN: 102381206
AMJ: 102567707(CFD)
PSS: 112545587
CMY: 102931053(CFD)
CPIC: 101935732(CFD)
PVT: 110072602(CFD)
PBI: 103066225
PMUR: 107282291(CFD)
TSR: 106542872
PMUA: 114588305(CFD)
GJA: 107120759(CFD)
XLA: 494791(cfd.L)
XTR: 394945(cfd)
NPR: 108798700
DRE: 553553(cfd)
SRX: 107733667
SGH: 107556907
IPU: 100862744
PHYP: 113544922
AMEX: 103044529
EEE: 113579255
TRU: 101070023
LCO: 104926791
NCC: 104963116
MZE: 101478226
ONL: 100692083
OLA: 100049308(olklklp)
XMA: 102225583
XCO: 114134801
PRET: 103458165
CVG: 107087104
NFU: 107373416
KMR: 108250570
ALIM: 106519943
AOCE: 111580112
CSEM: 103383188
POV: 109640960
LCF: 108889155
SDU: 111225539
SLAL: 111646789
HCQ: 109511554
BPEC: 110155605
MALB: 109962455
SASA: 101448046
OTW: 112265777
SALP: 112075441
ELS: 105015868
SFM: 108919827
PKI: 111860508
CLEC: 106662046
 » show all
Reference
  Authors
Sim RB, Tsiftsoglou SA
  Title
Proteases of the complement system.
  Journal
Biochem Soc Trans 32:21-7 (2004)
DOI:10.1042/bst0320021
Reference
PMID:1374388
  Authors
White RT, Damm D, Hancock N, Rosen BS, Lowell BB, Usher P, Flier JS, Spiegelman BM
  Title
Human adipsin is identical to complement factor D and is expressed at high levels in adipose tissue.
  Journal
J Biol Chem 267:9210-3 (1992)
  Sequence
[hsa:1675]
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