KEGG   ORTHOLOGY: K01351
Entry
K01351                      KO                                     
Symbol
KLK3, PSA
Name
semenogelase [EC:3.4.21.77]
Pathway
map05200  Pathways in cancer
map05215  Prostate cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K01351  KLK3, PSA; semenogelase
  09162 Cancer: specific types
   05215 Prostate cancer
    K01351  KLK3, PSA; semenogelase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors
    K01351  KLK3, PSA; semenogelase
Enzymes [BR:ko01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.21  Serine endopeptidases
    3.4.21.77  semenogelase
     K01351  KLK3, PSA; semenogelase
Peptidases and inhibitors [BR:ko01002]
 Serine peptidases
  Family S1: chymotrypsin family
   K01351  KLK3, PSA; semenogelase
Genes
HSA: 354(KLK3)
PTR: 493182(KLK3)
PPS: 100996069(KLK3)
GGO: 101143851(KLK3)
PON: 100432364(KLK3)
PPYG: 129020783(KLK3)
NLE: 100585512
HMH: 116478137(KLK3)
SSYN: 129460307
MCC: 719444(KLK3)
MCF: 102138599(KLK3)
MTHB: 126943121
MNI: 105497141
CSAB: 103235103(KLK3)
CATY: 105595343(KLK3)
PANU: 100127349(KLK3)
TGE: 112613502
MLEU: 105528939(KLK3)
RRO: 104667244
RBB: 108532415(KLK3)
TFN: 117091652
PTEH: 111519951(KLK3)
CANG: 105514724
 » show all
Reference
PMID:1725227
  Authors
Espana F, Gilabert J, Estelles A, Romeu A, Aznar J, Cabo A
  Title
Functionally active protein C inhibitor/plasminogen activator inhibitor-3 (PCI/PAI-3) is secreted in seminal vesicles, occurs at high concentrations in human seminal plasma and complexes with prostate-specific antigen.
  Journal
Thromb Res 64:309-20 (1991)
DOI:10.1016/0049-3848(91)90002-E
  Sequence
[hsa:354]
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