KEGG   ORTHOLOGY: K01370
Entry
K01370                      KO                                     

Name
CASP1
Definition
caspase 1 [EC:3.4.22.36]
Pathway
ko04217  Necroptosis
ko04613  Neutrophil extracellular trap formation
ko04621  NOD-like receptor signaling pathway
ko04623  Cytosolic DNA-sensing pathway
ko04625  C-type lectin receptor signaling pathway
ko05014  Amyotrophic lateral sclerosis
ko05130  Pathogenic Escherichia coli infection
ko05131  Shigellosis
ko05132  Salmonella infection
ko05133  Pertussis
ko05134  Legionellosis
ko05135  Yersinia infection
ko05164  Influenza A
ko05171  Coronavirus disease - COVID-19
ko05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    K01370  CASP1; caspase 1
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    K01370  CASP1; caspase 1
   04621 NOD-like receptor signaling pathway
    K01370  CASP1; caspase 1
   04623 Cytosolic DNA-sensing pathway
    K01370  CASP1; caspase 1
   04625 C-type lectin receptor signaling pathway
    K01370  CASP1; caspase 1
 09160 Human Diseases
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    K01370  CASP1; caspase 1
   05164 Influenza A
    K01370  CASP1; caspase 1
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    K01370  CASP1; caspase 1
   05132 Salmonella infection
    K01370  CASP1; caspase 1
   05131 Shigellosis
    K01370  CASP1; caspase 1
   05135 Yersinia infection
    K01370  CASP1; caspase 1
   05133 Pertussis
    K01370  CASP1; caspase 1
   05134 Legionellosis
    K01370  CASP1; caspase 1
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    K01370  CASP1; caspase 1
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    K01370  CASP1; caspase 1
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors
    K01370  CASP1; caspase 1
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K01370  CASP1; caspase 1
Enzymes [BR:ko01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.22  Cysteine endopeptidases
    3.4.22.36  caspase-1
     K01370  CASP1; caspase 1
Peptidases and inhibitors [BR:ko01002]
 Cysteine peptidases
  Family C14: caspase family
   K01370  CASP1; caspase 1
Membrane trafficking [BR:ko04131]
 Autophagy
  Other autophagy associated proteins
   TRIM-directed selective autophagy
    K01370  CASP1; caspase 1
Genes
HSA: 834(CASP1)
PTR: 101058924(CASP1)
PPS: 100985633(CARD17) 100985973 100986637(CARD16)
GGO: 101136563
PON: 100437679(CASP1) 100442809
NLE: 100588974(CASP1)
MCC: 100426388 706568
MCF: 102118885(CASP1)
CSAB: 103248363 103248365(CASP1) 103248933
RRO: 104665271(CASP1) 104665273 104665280
CJC: 100385618(CASP1)
SBQ: 101048062(CASP1)
MMU: 12362(Casp1)
MCAL: 110302061(Casp1)
MPAH: 110328145(Casp1)
RNO: 25166(Casp1)
MUN: 110552936
CGE: 100759171
NGI: 103743236(Casp1)
HGL: 101725179(Casp1)
CCAN: 109694935(Casp1)
OCU: 100101588(CASP1)
TUP: 102490614(CASP1)
BTA: 514214(CASP1)
BIU: 109570010(CASP1)
BBUB: 102395839(CASP1)
OAS: 101117013
SSC: 397319(CASP1)
CFR: 102514999(CASP1)
CDK: 105100418(CASP1)
BACU: 103013120
LVE: 103078860
OOR: 101289850(CASP1)
DLE: 111167579(CASP1)
PCAD: 102982110(CASP1)
ECB: 100033888(CASP1)
EPZ: 103559838(CASP1)
EAI: 106837656(CASP1)
MYB: 102247565 102258149(CASP1)
MYD: 102769699
MNA: 107532340
HAI: 109377701(CASP1)
DRO: 112314315(CASP1)
RAY: 107504293(CASP1)
TMU: 101359297
SHR: 100935043
OAA: 100078458
GGA: 395764(CASP1)
MGP: 100549639
CJO: 107322632
NMEL: 110407545 110407549(CARD16)
APLA: 101789899
ACYG: 106041090
FPG: 101914004
FCH: 102051371
CLV: 102097973
EGZ: 104131761
NNI: 104012458
ACUN: 113487354
PADL: 103916608
AAM: 106484675
ASN: 102373345
AMJ: 102575910(CASP1)
PSS: 102454294
CMY: 102948326
CPIC: 101951713
ACS: 100554079
PVT: 110084544
PBI: 103067193
PMUR: 107288559
PMUA: 114585476
GJA: 107112418
XLA: 378669(casp1.S) 397719(casp1.L)
XTR: 100491605(casp1)
NPR: 108790873
DRE: 566185(caspbl) 57933(caspa)
IPU: 108267794(CASP1)
PHYP: 113540111
LCO: 104924732
NCC: 104959782
OLA: 101174762
PRET: 103474681
NFU: 107380030
AOCE: 111582467
CSEM: 103378482
POV: 109630250
LCF: 108891827
SLAL: 111654143
BPEC: 110163616
SASA: 106612902
ELS: 105011822
SFM: 108922456
PKI: 111841516
LCM: 102363742
CMK: 103180499(caspase-1)
RTP: 109916765
 » show all
Reference
PMID:7780029
  Authors
Keane KM, Giegel DA, Lipinski WJ, Callahan MJ, Shivers BD
  Title
Cloning, tissue expression and regulation of rat interleukin 1 beta converting enzyme.
  Journal
Cytokine 7:105-10 (1995)
DOI:10.1006/cyto.1995.1014
  Sequence
[rno:25166]
Reference
PMID:1373520
  Authors
Cerretti DP, Kozlosky CJ, Mosley B, Nelson N, Van Ness K, Greenstreet TA, March CJ, Kronheim SR, Druck T, Cannizzaro LA, et al.
  Title
Molecular cloning of the interleukin-1 beta converting enzyme.
  Journal
Science 256:97-100 (1992)
DOI:10.1126/science.1373520
  Sequence
[hsa:834]
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