KEGG ORTHOLOGY: K02620

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    K02620  TCF7, TCF-1; transcription factor 7
   04390 Hippo signaling pathway
    K02620  TCF7, TCF-1; transcription factor 7
09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    K02620  TCF7, TCF-1; transcription factor 7
   04550 Signaling pathways regulating pluripotency of stem cells
    K02620  TCF7, TCF-1; transcription factor 7
09150 Organismal Systems
  09152 Endocrine system
   04916 Melanogenesis
    K02620  TCF7, TCF-1; transcription factor 7
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K02620  TCF7, TCF-1; transcription factor 7
  09162 Cancer: specific types
   05210 Colorectal cancer
    K02620  TCF7, TCF-1; transcription factor 7
   05225 Hepatocellular carcinoma
    K02620  TCF7, TCF-1; transcription factor 7
   05226 Gastric cancer
    K02620  TCF7, TCF-1; transcription factor 7
   05216 Thyroid cancer
    K02620  TCF7, TCF-1; transcription factor 7
   05221 Acute myeloid leukemia
    K02620  TCF7, TCF-1; transcription factor 7
   05217 Basal cell carcinoma
    K02620  TCF7, TCF-1; transcription factor 7
   05215 Prostate cancer
    K02620  TCF7, TCF-1; transcription factor 7
   05213 Endometrial cancer
    K02620  TCF7, TCF-1; transcription factor 7
   05224 Breast cancer
    K02620  TCF7, TCF-1; transcription factor 7
  09166 Cardiovascular disease
   05412 Arrhythmogenic right ventricular cardiomyopathy
    K02620  TCF7, TCF-1; transcription factor 7
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    K02620  TCF7, TCF-1; transcription factor 7
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    K02620  TCF7, TCF-1; transcription factor 7
  09172 Infectious disease: viral
   05167 Kaposi sarcoma-associated herpesvirus infection
    K02620  TCF7, TCF-1; transcription factor 7
   05165 Human papillomavirus infection
    K02620  TCF7, TCF-1; transcription factor 7
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K02620  TCF7, TCF-1; transcription factor 7
Transcription factors [BR:ko03000]
Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   HMG TCF-1
    K02620  TCF7, TCF-1; transcription factor 7

Genes

HSA:	6932(TCF7)

PTR:	745839(TCF7)

PPS:	100980839(TCF7)

GGO:	101149731(TCF7)

PON:	100461234(TCF7)

NLE:	100595737(TCF7)

MCC:	710234(TCF7)

MCF:	102142248(TCF7)

CSAB:

103244543(TCF7)

RRO:	104659811(TCF7)

RBB:	108529562(TCF7)

CJC:	100399154(TCF7)

SBQ:	101029076(TCF7)

MMU:	21414(Tcf7)

MCAL:

110304948(Tcf7)

MPAH:

110332085(Tcf7)

RNO:	363595(Tcf7)

MUN:	110549622(Tcf7)

CGE:	100757390(Tcf7)

NGI:	103729786(Tcf7)

HGL:	101707882(Tcf7)

CCAN:

109689465(Tcf7)

OCU:	100339216(TCF7)

TUP:	102484318(TCF7)

CFA:	481506(TCF7)

VVP:	112917059(TCF7)

AML:	100476528(TCF7)

UMR:	103663815(TCF7)

UAH:	113261735(TCF7)

ORO:	101376237(TCF7)

ELK:

111141244

FCA:	101098768(TCF7)

PTG:	102957988(TCF7)

PPAD:

109250863(TCF7)

AJU:	106984911(TCF7)

BTA:	782690(TCF7)

BOM:	102266633(TCF7)

BIU:	109562015(TCF7)

BBUB:

102408996(TCF7)

CHX:	102173736(TCF7)

OAS:	101101980(TCF7)

SSC:	100512951(TCF7)

CFR:	102519063(TCF7)

CDK:	105090254(TCF7)

BACU:

103018264(TCF7)

LVE:	103074150(TCF7)

OOR:	101289599(TCF7)

DLE:	111182442(TCF7)

PCAD:

102992878(TCF7)

ECB:	100072786(TCF7)

EPZ:	103543120(TCF7)

EAI:	106834657(TCF7)

MYB:	102250528(TCF7)

MYD:	102757003(TCF7)

MNA:	107525397(TCF7)

HAI:	109382635(TCF7)

DRO:	112318180(TCF7)

PALE:

102885788(TCF7)

RAY:	107506797(TCF7)

MJV:	108406081(TCF7)

LAV:	100663559(TCF7)

TMU:

101350837

MDO:	100017589(TCF7)

SHR:	100930141(TCF7)

PCW:	110211723(TCF7)

OAA:	100082332(TCF7)

GGA:	395229(TCF7)

MGP:	100544924(TCF7)

CJO:	107320225(TCF7)

NMEL:

110405287(TCF7)

APLA:

101803610(TCF7)

ACYG:

106032766(TCF7)

TGU:	100221008(TCF7)

LSR:	110481074(TCF7)

SCAN:

103817470(TCF7)

GFR:	102036749(TCF7)

FAB:	101820491(TCF7)

PHI:	102110510(TCF7)

PMAJ:

107210639(TCF7)

CCAE:

111935599(TCF7)

CCW:	104683724(TCF7)

ETL:	114063910(TCF7)

FPG:	101919678(TCF7)

FCH:	102058554(TCF7)

CLV:	102094656(TCF7)

EGZ:	104133478(TCF7)

NNI:	104012004(TCF7)

ACUN:

113485114(TCF7)

PADL:

103915850(TCF7)

AAM:	106487174(TCF7)

ASN:	102383175(TCF7)

AMJ:	102576120(TCF7)

PSS:	102446665(TCF7)

CMY:

102943166

CPIC:

101937399(TCF7)

ACS:	100554608(tcf7)

PVT:	110079405(TCF7)

PBI:	103067042(TCF7)

PMUR:

107294908(TCF7)

TSR:	106542632(TCF7)

PMUA:

114591268(TCF7)

GJA:	107125983(TCF7)

XLA:	398658(tcf7.S)

XTR:	395061(tcf7)

NPR:	108792126(TCF7)

DRE:	497649(tcf7)

SRX:	107728269 107742437(tcf7)

SANH:

107661683(tcf7) 107692971

SGH:	107557295 107603263

CCAR:

109048020

IPU:	108278866(tcf7)

PHYP:

113535749

AMEX:

103045826

EEE:	113578029(tcf7)

TRU:	101076516(tcf7)

LCO:

104924428

NCC:	104960861(tcf7)

MZE:	101469770(tcf7)

ONL:	100710520(tcf7)

OLA:	101162309(tcf7) 101162335 111947120

XMA:	102221228(tcf7) 111610761

XCO:	114152465(tcf7) 114157642

PRET:

103460015(tcf7) 103480959

CVG:	107085909(tcf7)

NFU:	107378492 107386837(tcf7)

KMR:	108238102(tcf7)

ALIM:

106524564(tcf7) 106532889

AOCE:

111566135

CSEM:

103394864(tcf7)

POV:	109635808(tcf7)

LCF:	108893669(tcf7)

SDU:	111234495(tcf7)

SLAL:

111659992(tcf7)

HCQ:	109515640 109531063

MALB:

109966812(tcf7)

SASA:

106567524 106603814

OTW:	112228202 112246539 112258094

SALP:

111979956 112069673

ELS:

105026693

SFM:	108929645 108934364

PKI:

111839551

LCM:	102350321(TCF7)

CMK:	103183678(tcf7)

RTP:

CBR:

MYI:

Reference

PMID:1569101

Authors

van de Wetering M, Oosterwegel M, Holstege F, Dooyes D, Suijkerbuijk R, Geurts van Kessel A, Clevers H

Title

The human T cell transcription factor-1 gene. Structure, localization, and promoter characterization.

Journal

J Biol Chem 267:8530-6 (1992)

Sequence

[hsa:6932]

Reference

PMID:17143293

Authors

Arce L, Yokoyama NN, Waterman ML

Title

Diversity of LEF/TCF action in development and disease.

Journal

Oncogene 25:7492-504 (2006)
DOI:10.1038/sj.onc.1210056

Reference

PMID:11477404

Authors

Ioannidis V, Beermann F, Clevers H, Held W

Title

The beta-catenin--TCF-1 pathway ensures CD4(+)CD8(+) thymocyte survival.

Journal

Nat Immunol 2:691-7 (2001)
DOI:10.1038/90623

Sequence

[mmu:21414]

LinkDB

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