KEGG ORTHOLOGY: K03754

ORTHOLOGY: K03754

Entry

K03754                      KO

Symbol

EIF2B2

Name

translation initiation factor eIF-2B subunit beta

Pathway

map05168

Herpes simplex virus 1 infection

Disease

H00869

Leukoencephalopathy with vanishing white matter

Brite

KEGG Orthology (KO) [BR:ko00001]
09160 Human Diseases
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    K03754  EIF2B2; translation initiation factor eIF-2B subunit beta
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03012 Translation factors
    K03754  EIF2B2; translation initiation factor eIF-2B subunit beta
Translation factors [BR:ko03012]
Eukaryotic type
  Initiation factors
   eIF-2B
    K03754  EIF2B2; translation initiation factor eIF-2B subunit beta

Other DBs

COG:

COG1184

GO:

0003743

Genes

HSA:	8892(EIF2B2)

PTR:	453042(EIF2B2)

PPS:	100984717(EIF2B2)

GGO:	101125653(EIF2B2)

PON:	100461180(EIF2B2)

PPYG:

129012604(EIF2B2)

NLE:	100584234(EIF2B2)

HMH:	116484844(EIF2B2)

SSYN:

129487651(EIF2B2)

MCC:	701360(EIF2B2)

MCF:	101866679(EIF2B2)

MTHB:

126959551

MNI:	105495779(EIF2B2)

CSAB:

103229342(EIF2B2)

CATY:

105590862(EIF2B2)

PANU:

101018813(EIF2B2)

TGE:	112629259(EIF2B2)

MLEU:

105540799(EIF2B2)

RRO:	104677583(EIF2B2)

RBB:	108534922(EIF2B2)

TFN:	117069323(EIF2B2)

PTEH:

111520987(EIF2B2)

CANG:

105517146(EIF2B2)

CJC:	100387159(EIF2B2)

SBQ:	101043072(EIF2B2)

CIMI:

108304449(EIF2B2)

ANAN:

105707309(EIF2B2)

CSYR:

103266533(EIF2B2)

MMUR:

105858771(EIF2B2)

LCAT:

123646601(EIF2B2)

PCOQ:

105819910(EIF2B2)

OGA:	100951653(EIF2B2)

MMU:	217715(Eif2b2)

MCAL:

110306835(Eif2b2)

MPAH:

110324472(Eif2b2)

RNO:	84005(Eif2b2)

MCOC:

116080502(Eif2b2)

ANU:	117696949(Eif2b2)

ASYL:

127687107(Eif2b2)

MUN:	110546956(Eif2b2)

CGE:	100759048(Eif2b2)

MAUA:

101832944(Eif2b2)

PROB:

127230988(Eif2b2)

PLEU:

114698083(Eif2b2)

MORG:

121452290(Eif2b2)

MFOT:

126515187

AAMP:

119818905(Eif2b2)

NGI:	103747349(Eif2b2)

HGL:	101724125(Eif2b2)

CPOC:

100734729(Eif2b2)

CCAN:

109693996(Eif2b2)

DORD:

106002525(Eif2b2)

DSP:	122118802(Eif2b2)

PLOP:

125363250(Eif2b2)

NCAR:

124975966

MMMA:

107149289(Eif2b2)

ITI:	101957794(Eif2b2)

OCU:	100009318(EIF2B2)

OPI:	101527461(EIF2B2)

TUP:	102490361(EIF2B2)

GVR:	103586268(EIF2B2)

CFA:	490789(EIF2B2)

CLUD:

112657741(EIF2B2)

VVP:	112927285(EIF2B2)

VLG:	121492998(EIF2B2) 121498693

NPO:	129496371(EIF2B2)

AML:	100473858(EIF2B2)

UMR:	103671068(EIF2B2)

UAH:	113270323(EIF2B2)

UAR:	123798975(EIF2B2)

ELK:

111148707

LLV:

125104591

MPUF:

101688887(EIF2B2)

MNP:	132000162(EIF2B2)

MLK:	131836862(EIF2B2)

NVS:	122891120 122894175(EIF2B2)

ORO:	101369416(EIF2B2)

EJU:	114207976(EIF2B2)

ZCA:	113909872(EIF2B2)

MLX:	118002028(EIF2B2)

NSU:	110571450(EIF2B2)

LWW:	102730070(EIF2B2)

FCA:	101096323(EIF2B2)

PYU:	121032058(EIF2B2)

PCOO:

112856039(EIF2B2)

PBG:	122469338(EIF2B2)

PVIV:

125167594(EIF2B2)

LRUF:

124512639

LGF:	123584085(EIF2B2)

PTG:	102960310(EIF2B2)

PPAD:

109253845(EIF2B2)

PUC:

125909342

PLEZ:

122222945(EIF2B2)

AJU:

106974358

HHV:	120231982(EIF2B2)

BTA:	513958(EIF2B2)

BOM:	102273733(EIF2B2)

BIU:	109565357(EIF2B2)

BBUB:

102390622(EIF2B2)

BBIS:

105000063(EIF2B2)

CHX:	102184443(EIF2B2)

OAS:	101108921(EIF2B2)

BTAX:

128054132(EIF2B2)

CSUM:

138070377(EIF2B2)

ODA:	120852710(EIF2B2)

CCAD:

122443866(EIF2B2)

MREE:

136172137(EIF2B2)

OVR:	110146203(EIF2B2)

MBEZ:

129562488(EIF2B2)

SSC:	100515216(EIF2B2)

CFR:	102520690(EIF2B2)

CBAI:

105075211(EIF2B2)

CDK:	105086093(EIF2B2)

VPC:	102531625(EIF2B2)

BACU:

103018030(EIF2B2)

BMUS:

118891002(EIF2B2)

LVE:	103082506(EIF2B2)

OOR:	101284780(EIF2B2)

LALB:

132511982(EIF2B2)

DLE:	111176245(EIF2B2)

PCAD:

102979709(EIF2B2)

PSIU:

116748721(EIF2B2)

NASI:

112394824(EIF2B2)

ECB:	100057247(EIF2B2)

EPZ:	103548611(EIF2B2)

EAI:	106827723(EIF2B2)

MYB:	102243338(EIF2B2)

MYD:	102761576(EIF2B2)

MMYO:

118658148(EIF2B2)

MLF:	102421003(EIF2B2) 102421870

MDT:	132231347(EIF2B2)

MYUM:

139011192(EIF2B2)

PKL:	118715220(EIF2B2)

EFUS:

103283569(EIF2B2)

MNA:	107533830(EIF2B2)

DRO:	112311651(EIF2B2)

SHON:

118976810(EIF2B2)

AJM:	119036521(EIF2B2)

PDIC:

114491822(EIF2B2)

PHAS:

123808304(EIF2B2)

MMF:	118617231(EIF2B2)

PPAM:

129065889(EIF2B2)

HAI:	109381520(EIF2B2)

RFQ:	117024140(EIF2B2)

PALE:

102890039(EIF2B2)

PGIG:

120619512(EIF2B2)

PVP:	105299220(EIF2B2)

RAY:	107498904(EIF2B2)

MJV:	108399232(EIF2B2)

TOD:	119239358(EIF2B2)

SARA:

101543904(EIF2B2)

SFUM:

130041450(EIF2B2)

SETR:

126004050(EIF2B2)

LAV:	100675367(EIF2B2)

TMU:

101355575

ETF:	101640636(EIF2B2)

DNM:	101445569(EIF2B2)

MDO:	100018522(EIF2B2)

GAS:	123235858(EIF2B2) 123256330

SHR:	100925215(EIF2B2)

AFZ:

127549492

PCW:	110208320(EIF2B2)

TVP:	118829421(EIF2B2)

PBRV:

138164426(EIF2B2)

OAA:	100085404(EIF2B2)

TACU:

119944794(EIF2B2)

GGA:	423359(EIF2B2)

PCOC:

116229411(EIF2B2)

MGP:	100543153(EIF2B2)

CJO:	107315094(EIF2B2)

TPAI:

128086960(EIF2B2)

LMUT:

125694817(EIF2B2)

NMEL:

110402134(EIF2B2)

APLA:

101801118(EIF2B2)

ACYG:

106038830(EIF2B2)

CATA:

118244471(EIF2B2)

AFUL:

116489336(EIF2B2)

TGU:	100190609(EIF2B2)

LSR:	110477227(EIF2B2)

SCAN:

103826523(EIF2B2)

PMOA:

120500465(EIF2B2)

OTC:	121332211(EIF2B2)

PRUF:

121355923(EIF2B2)

ATRC:

139589918(EIF2B2)

GFR:	102032650(EIF2B2)

FAB:	101806486(EIF2B2)

OMA:	130254166(EIF2B2)

PHI:	102104085(EIF2B2)

PMAJ:

107205951(EIF2B2)

CCAE:

111929971(EIF2B2)

CCW:	104685198(EIF2B2)

CBRC:

103621038(EIF2B2)

ACOE:

138111699(EIF2B2)

ETL:	114056010(EIF2B2)

ZAB:	102068544(EIF2B2)

ZLE:	135448027(EIF2B2)

ACHL:

103801531(EIF2B2)

SVG:	106861709(EIF2B2)

MMEA:

130578414(EIF2B2)

HRT:	120754620(EIF2B2)

SATI:

136363002(EIF2B2)

CCIC:

134045388(EIF2B2)

FPG:	101920847(EIF2B2)

FCH:	102059815(EIF2B2)

CCRI:

104155710(EIF2B2)

NNT:	104401966(EIF2B2)

SHAB:

115606007(EIF2B2)

ACUN:

113480339(EIF2B2)

TALA:

104362972(EIF2B2)

ACHC:

115350903(EIF2B2)

HALD:

104311326(EIF2B2)

HLE:	104841809(EIF2B2)

AGEN:

126049153

HHAR:

128139813(EIF2B2)

GCL:

127016419

CSTI:

104559522(EIF2B2)

LDI:	104353273(EIF2B2)

MNB:	103773764(EIF2B2)

DPUB:

104308195(EIF2B2)

PPUS:

135178699(EIF2B2)

AVIT:

104268498(EIF2B2)

BRHI:

104497360(EIF2B2)

EGZ:	104133283(EIF2B2)

NNI:	104020991(EIF2B2)

PCRI:

104037825(EIF2B2)

PCAO:

104040054(EIF2B2)

PADL:

103912963(EIF2B2)

AFOR:

103900262(EIF2B2)

FGA:	104070586(EIF2B2)

GSTE:

104258894(EIF2B2)

CLV:	102087395(EIF2B2)

MUI:	104534377(EIF2B2)

PGUU:

104468242(EIF2B2)

PLET:

104616923(EIF2B2)

EHS:	104509190(EIF2B2)

CMAC:

104480010(EIF2B2)

CUCA:

104061665(EIF2B2)

TEO:	104378405(EIF2B2)

BREG:

104630416(EIF2B2)

OHA:	104334100(EIF2B2)

ACAR:

104527355(EIF2B2)

CPEA:

104385433(EIF2B2)

CVF:	104288203(EIF2B2)

RTD:	128908385(EIF2B2)

AAM:	106482871(EIF2B2)

AROW:

112960519(EIF2B2)

NPD:	112957950(EIF2B2)

TGT:	104579143(EIF2B2)

DNE:	112995397(EIF2B2)

SCAM:

104141537(EIF2B2)

ASN:	102385807(EIF2B2)

AMJ:	102561022(EIF2B2)

CPOO:

109321265(EIF2B2)

GGN:	109298614(EIF2B2)

PSS:	102452982(EIF2B2)

CMY:	102941577(EIF2B2)

CCAY:

125637595(EIF2B2)

DCC:	119857166(EIF2B2)

CPIC:

101935106(EIF2B2)

TST:	117876386(EIF2B2)

CABI:

116837539(EIF2B2)

MRV:	120403688(EIF2B2)

ACS:	100552697(eif2b2)

ASAO:

132764407(EIF2B2)

PVT:	110079079(EIF2B2)

SUND:

121930805(EIF2B2)

PBI:	103067765(EIF2B2)

PMUR:

107293079(EIF2B2)

CTIG:

120311772(EIF2B2)

TSR:	106545089(EIF2B2)

PGUT:

117665831(EIF2B2)

APRI:

131187769(EIF2B2)

PTEX:

113443542(EIF2B2)

NSS:	113410038(EIF2B2)

VKO:	123026438(EIF2B2)

PMUA:

114591893(EIF2B2)

PRAF:

128409064(EIF2B2)

ZVI:	118081852(EIF2B2)

HCG:	128340616(EIF2B2)

GJA:	107118332(EIF2B2)

STOW:

125426543(EIF2B2)

EMC:	129323647(EIF2B2)

XLA:	379960(eif2b2.L)

XTR:	496931(eif2b2)

NPR:	108802483(EIF2B2)

RTEM:

120920633(EIF2B2)

BGAR:

122942085(EIF2B2)

PWL:	138260206(EIF2B2)

GSH:	117361084 117363460(EIF2B2)

DRE:	405839(eif2b2)

SRX:	107719358 107742715

SANH:

107685362 107697194

SGH:	107550419(eif2b2) 107593258

CCAR:

109080935

CAUA:

113083365 113097324 113120643

CGIB:

127938739 127984153

PTET:

122324464(eif2b2)

LROH:

127183305(eif2b2)

OMC:	131527398(eif2b2)

PPRM:

120460313(eif2b2)

RKG:	130103003(eif2b2)

MAMB:

125278490(eif2b2)

CIDE:

127502074

CERY:

137019191(eif2b2)

MASI:

127409696 127415674

TROS:

130565574 130566025

TDW:	130434554(eif2b2)

MANU:

129429928(eif2b2)

PDAB:

135738360(eif2b2)

IPU:

108255365

IFU:	128618064(eif2b2)

SMEO:

124401610(eif2b2)

TFD:	113651677(eif2b2)

TVC:	132855414(eif2b2)

CGAR:

128518001(eif2b2)

NGRA:

132876977(eif2b2)

TRN:	134319801(eif2b2)

AMEX:

103034429(eif2b2)

CMAO:

118816008(eif2b2)

EEE:	113590127(eif2b2)

CHAR:

105889795(eif2b2)

SPIL:

134097688(eif2b2)

TRU:	101078626(eif2b2)

TFS:	130516372(eif2b2)

TNG:	GSTEN00030335G001

LCO:

104921450

NCC:	104951066(eif2b2)

TBEN:

117492173(eif2b2)

CGOB:

115003568(eif2b2)

PGEO:

117439954(eif2b2)

GACU:

117533800(eif2b2)

EMAC:

134876947(eif2b2)

ELY:	117270597(eif2b2)

EFO:	125896930(eif2b2)

PLEP:

121955603(eif2b2) 121965714

SLUC:

116066396(eif2b2)

ECRA:

117961722(eif2b2)

ESP:	116706485(eif2b2)

PFLV:

114573344(eif2b2)

GAT:	120808495(eif2b2)

PPUG:

119194917(eif2b2)

AFB:	129107325(eif2b2)

CLUM:

117727899(eif2b2)

PSWI:

130202585(eif2b2)

CANA:

137785766(eif2b2)

CVE:	137882299(eif2b2)

MSAM:

119909243(eif2b2)

SCHU:

122862758(eif2b2)

CUD:	121521559(eif2b2)

SPUL:

138585030(eif2b2)

LMIX:

132985011(eif2b2)

ALAT:

119013143(eif2b2)

ASTR:

137613509(eif2b2)

MZE:	101486741(eif2b2)

ONL:	100708663(eif2b2)

OAU:	116310786 116314104

OLA:	101167261(eif2b2)

OML:	112158527(eif2b2)

CSAI:

133464687(eif2b2)

XMA:	102224563(eif2b2)

XCO:	114158177(eif2b2)

XHE:	116734164(eif2b2)

PRET:

103457602(eif2b2)

PFOR:

103138631(eif2b2)

PLAI:

106938760(eif2b2)

PMEI:

106920012(eif2b2)

GAF:	122825529(eif2b2)

PPRL:

129351173(eif2b2)

CVG:	107083159(eif2b2)

CTUL:

119785102(eif2b2)

GMU:	124882153(eif2b2)

NFU:	107377526(eif2b2)

KMR:	108242477(eif2b2)

ALIM:

106516921(eif2b2)

NWH:	119418188(eif2b2)

AOCE:

111566663(eif2b2)

EJA:	138193809(eif2b2)

BFRE:

138619835(eif2b2)

MCEP:

124998633(eif2b2)

CSEM:

103380802(eif2b2)

POV:	109636013(eif2b2)

SSEN:

122783741(eif2b2)

HHIP:

117758556(eif2b2)

HSP:	118099410(eif2b2)

PPLT:

128460138(eif2b2)

SMAU:

118290546(eif2b2)

LCF:

108895654

SDU:	111240360(eif2b2)

SLAL:

111653032(eif2b2)

XGL:	120788656(eif2b2)

HCQ:	109524836(eif2b2)

SSCV:

125990319(eif2b2)

SBIA:

133496563(eif2b2)

PEE:	133416957(eif2b2)

PTAO:

133468105(eif2b2)

BPEC:

110154251(eif2b2)

MALB:

109970029(eif2b2)

BSPL:

114850091(eif2b2)

SSCO:

133997658(eif2b2)

SASA:

100195606(ei2bb) 106608291

STRU:

115151293 115175162

OTW:	112235304 112236225 121844091

OMY:	110522643 110529271

OGO:	123990478 123995454

ONE:	115116795 115118995

OKI:	109879523 109880624

OKE:	118376446 118378620 127931311

OMM:	135506246 135538354 135557980

SALP:

112070671 112072975

SNH:	120019202 120024391

CCLU:

121552621 121556165

ELS:	105005943(eif2b2)

SFM:	108930715(eif2b2)

PKI:	111852419(eif2b2)

AANG:

118230402(eif2b2)

AROT:

135251179(eif2b2)

CCOG:

133125039(eif2b2)

LOC:	102685939(eif2b2)

PSPA:

121324747 121329949

ARUT:

117421798 117423541

PSEX:

120519168(eif2b2)

LCM:	102364409(EIF2B2)

CMK:	103189961(eif2b2)

RTP:	109926559(eif2b2)

CPLA:

122555454(eif2b2)

HOC:	132818455(eif2b2)

LERI:

129700101(eif2b2)

PMRN:

116937581(EIF2B2)

LRJ:	133346202(EIF2B2)

BFO:

BBEL:

CIN:

SCLV:

SPU:

LPIC:

APLC:

ARUN:

AJC:

SKO:

PFLL:

DME:	Dmel_CG2677(eIF2Bbeta)

DER:

6551224

DSE:

6616182

DSI:	Dsimw501_GD16616(Dsim_GD16616)

DYA:	Dyak_GE16274

DAN:

DSR:

DPO:

DPE:

DMN:	108159239 117191670 117191671

DWI:

6641494

DGR:

6565364

DMO:	Dmoj_GI15870

DAZ:

108618784

DNV:

108656364

DHE:

111605319

DVI:	6636653(eIF2Bbeta)

CCAT:

105664432

BOD:

106624763

BDR:	105225183 125778468

RZE:	108364346 108377944

AOQ:

TDA:

MDE:

SCAC:

LCQ:

LSQ:

CVJ:	135956490(eIF2Bbeta)

GFS:

119637563

ECOE:

129946482

CLON:

129615643 129615654 129615655

HIS:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AFUN:

AMOU:

AALI:

AAG:

AALB:

ASUA:

CQU:	CpipJ_CPIJ015788

CPII:

CNS:

BCOO:

LLL:

PPAP:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BHUN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

COBS:

139110201(Eif2bbeta)

HST:

DQU:

CFO:

FEX:

PMEC:

138943393(Eif2bbeta)

LHU:	105668389(eIF2Bbeta)

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

TPRE:

LHT:

LBD:

MDL:

CGLO:

FAS:

DAM:

AGIF:

CINS:

VCAN:

CCIN:

DSM:

NPT:	124222484(eIF2Bbeta)

NFB:

NLO:

NVG:

AROA:

TCA:

TMOL:

138137371(eIF2Bbeta)

DPA:

109540709

ESIM:

136416727(eIF2Bbeta)

EFOR:

136346954(eIF2Bbeta)

SOY:

AGRG:

ATD:

CSET:

HAXR:

AGB:	108906083 111691322

LDC:

DVV:

NVL:

APLN:

PPYR:

OTU:

BMOR:

MCIX:

PPOT:

ZCE:

LSIN:

ATRA:

CFEL:

API:

DNX:

AGS:

RMD:

ACOO:

DVT:

BTAB:

DCI:

CLEC:

HHAL:

106678484(eIF2Bbeta)

NLU:

HVI:

MQU:

FOC:

TPAL:

ZNE:

CSEC:

SGRE:

BROR:

IEL:

FCD:

DPX:	DAPPUDRAFT_304186

DMK:

DPZ:

AFRA:

PVM:

PJA:

PCHN:

PMOO:

HAME:

PCLA:

123766511(eIF2Bbeta)

PTRU:

123503820

ESN:

127006774

MNZ:

135204162

MRJ:	136846604(eIF2Bbeta)

HAZT:

LSM:

TCF:

PPOI:

DSV:

RSAN:

RMP:

VDE:

VJA:

TUT:

DPTE:

DFR:

CSCU:

CVS:	136973347(eIF2Bbeta)

PTEP:

ABRU:

UDV:

LPOL:

PMEO:

CEL:	CELE_Y47H9C.7(eif-2Bbeta)

CBR:

CBG_15840

CRQ:	GCK72_001595

BMY:	BM_BM6630(Bma-eif-2Bbeta)

LOA:	LOAG_13668

TSP:

Tsp_06062

HRO:	HELRODRAFT_188412

LGI:	LOTGIDRAFT_204385

PVUL:

PCAN:

LSAX:

BGT:

GAE:

HRF:

HRJ:

HASI:

HCRA:

CRG:

CANU:

CVN:

OED:

MYI:

PMAX:

AIRR:

MCAF:

MMER:

RPHI:

DPOL:

MAEA:

OBI:

OSN:

LJP:

LAK:

SMM:	Smp_014620

SHX:	MS3_00006645(EIF2B2_1)

OVI:	T265_03569

EGL:

LLON:

NVE:

EPA:

ATEN:

AMIL:

MCAZ:

MFOO:

PDAM:

SPIS:

DGT:

XEN:

HMG:

HSY:

RES:

TAD:	TRIADDRAFT_58132

AQU:	100640519 100640884

ATH:

ALY:

CRB:

CSAT:

EUS:	EUTSA_v10007798mg

BRP:	103849359 103870682

BNA:	106451264 106452954 111206237 125601820

BOE:	106292586 106321545

RSZ:	108811357 108813735 108861997

THJ:	104818980 104822485

CPAP:

110806361

CIT:	102618607 102624845

CIC:	CICLE_v10001295mg CICLE_v10005415mg CICLE_v10006759mg

PVY:

MINC:

TCC:

GRA:

GHI:	107904422 107904723

GAB:

108453458

HSYR:

120154495 120157656 120207987

DZI:	111295370 111309999

EGR:

104454550

RARG:

115742318

GMX:	100778545 100801044 100807877

GSJ:	114368829 114375131 114418604

PVU:	137834810 137838021

VRA:	106761185 106774914

VAR:	108333145 108343748

VUN:	114164126 114180336

VUM:	124829633 124841836

CCAJ:

APRC:

MTR:

TPRA:

CAM:

PSAT:

VVO:	131650259 131650312

LJA:

130748582

ADU:

107471963

AIP:

107623491

AHF:	112716993 112783607

LANG:

109328541

PCIN:

129299903 129307442

QSA:	O6P43_003176 O6P43_029683

FVE:	101298118 101310833

AANS:

126789916 126801803

RCN:	112178583 112196359

PPER:

PMUM:

PAVI:

PDUL:

MDM:	103411508 103438548 103453492

MSYL:

126595333 126597061 126603850 126629871

PXB:	103942731 103945586 103952157

PCOX:

ZJU:

MNT:

CSAV:

CSV:

CMO:

BHJ:

MCHA:

CMAX:

CMOS:

CPEP:

RCU:	8263741 8270898

MEAN:

JCU:

HBR:

MESC:

POP:	112327014 7462782 7475407 7487011

PEU:	105108088 105122785 105129898

PALZ:

118048911 118054272 118061232

PNZ:	133682289 133697686 133701796

JRE:	108988930 108990757

CILL:

122292085 122294324

CAVE:

132176356

AGLU:

133879554

QSU:	111999363 112015180

QLO:	115986430 115986780 115994918

TWL:	119980913 120004889

VVI:

100256712

VRI:

117928807

SLY:	101258004 101266888

SPEN:

107004852 107031378

SOT:	102580093 102590114

SSTN:

125852298 125871792

SDUL:

129883166 129901115

CANN:

107850423 107864213

LBB:	132610184 132613779

NTA:	107759173 107762934(NIFb) 107806721 107815973

NSY:	104236671 104242505

NTO:	104093446 104120788

NAU:	109222233 109236942 109245063

INI:

ITR:

SIND:

OEU:

EGT:

SSPL:

121755675 121759216 121805793 121809596

SMIL:

SHIS:

APAN:

HAN:

ECAD:

LSV:	111902898 111918153

CCAV:

112502300 112512458

DCR:

108227382

CSIN:

114269023 114310324

RVL:	131315901 131334762

AEW:	130759776 130783498

DLT:

127800163

BVG:

104884434

SOE:	110790030 110802203

CQI:	110684944 110686373 110715184

ATRI:

MOF:

NNU:

MING:

TSS:

PSOM:

OSA:

OBR:

OGL:

BDI:

ATS:

TDC:	119267477 119331149

TAES:

123043971 123117906 123180878

TUA:

LPER:

LRD:

SBI:

ZMA:	100191235 100283019

MFLO:

SITA:

SVS:

PVIR:

PHAI:

PAUA:

PDA:	103707304 103716312

EGU:

105058611

MUS:

135626701

ZOF:	121982235 121986131 122031057 122033618

DCT:

110095827

PEQ:

110025830

AOF:	109833597 109848890

MSIN:

ACAK:

NCOL:

ATR:

CJF:	131060046 131079447

SMO:	SELMODRAFT_186716 SELMODRAFT_88504

PPP:	112273878 112287840

CRE:	CHLRE_16g662902v5

VCN:	VOLCADRAFT_68671(eif2Bb)

MNG:

MNEG_6493

CSL:	COCSUDRAFT_18960

CVR:	CHLNCDRAFT_24479

APRO:

F751_2607

OLU:	OSTLU_5458

OTA:	OT_ostta13g00970

BPG:	Bathy17g00520

MIS:	MICPUN_59380

CME:	CYME_CMT272C

GSL:	Gasu_12620

CCP:	CHC_T00008764001

SCE:	YLR291C(GCD7)

SEUB:

DI49_3798

SPAO:

SPAR_L03120

AGO:	AGOS_AGR292C

ERC:

Ecym_3099

KLA:	KLLA0_A04433g KLLA0_C05082g

KMX:	KLMA_10224(GCD7) KLMA_50132(GCD7)

LTH:	KLTH0G14894g

ZRO:	ZYRO0D14740g

CGR:	2888275(GVI51_G09515)

NCS:	NCAS_0F00430(NCAS0F00430)

NDI:	NDAI_0D02680(NDAI0D02680)

TPF:	TPHA_0F02750(TPHA0F02750)

TBL:	TBLA_0E01000(TBLA0E01000)

TGB:	HG536_0H03930

TDL:	TDEL_0G03830(TDEL0G03830)

KAF:	KAFR_0A04820(KAFR0A04820)

KNG:	KNAG_0F03160(KNAG0F03160)

ZMK:	HG535_0G02280

SLUD:

SCDLUD_000877

DHA:	DEHA2D10978g

PIC:	PICST_59263(GCD7)

PGU:	PGUG_00713

SPAA:

SPAPADRAFT_60515

LEL:	PVL30_000747(GCD7)

LBG:	92205536(LODBEIA_P03400)

CAL:	CAALFM_C203990WA(GCD7)

CTP:	CTRG_01445

COT:	CORT_0A08550

CDU:	CD36_18640

CTEN:

18246594(GCD7)

CLU:	CLUG_00155

CLUS:

A9F13_20g00880

CAUR:

CJI96_0002162

ASAU:

88171949(PUMCH_000881)

PPA:	PAS_chr3_0564

PKZ:	C5L36_0D03260

BNN:	FOA43_002290

BBRX:

BRETT_005066

OPA:	HPODL_03423

YLI:	2908723(YALI2_E01024g)

SLB:	AWJ20_4911(GCD7)

NCR:

NCU08952

NTE:	NEUTE1DRAFT37485(NEUTE1DRAFT_37485)

SMP:	10806729(SMAC4_05527)

PAN:	PODANSg9135

PBEL:

QC761_212710(GCD7)

PPSD:

QC762_212710(GCD7)

PPSP:

QC763_212710(GCD7)

PPSA:

QC764_212710(GCD7)

TTT:	THITE_2109048

MTM:	MYCTH_2302808

CTHR:

MGR:

PGRI:

SSCK:

FGR:	FGSG_10301

FPU:	FPSE_12374

FPOA:

FPOAC1_003403

FVN:	FVRRES_03750

FVR:	FVEG_03031

FOX:	FOXG_05104

NHE:	NECHADRAFT_80621

FFC:	NCS54_00720000

FKR:	NCS57_00760300

FMU:	J7337_005933

TRE:	TRIREDRAFT_82380

TRR:	M419DRAFT_143271

TATV:

25782455(TrAtP1_006930)

TASP:

36616552(TrAFT101_006135)

MAW:	19253553(GCD7_1)

MAJ:

MAA_03137

MBRN:

26241367(G6M90_00g077700)

PCHM:

VFPPC_09491

CMT:

CCM_03636

AMUS:

LMH87_007980

PLJ:	90642675(PLICBS_001971)

PTKZ:

JDV02_006957(GCD7)

VAL:	VDBG_00600

VDA:	VDAG_00213

CFJ:	CFIO01_02369

CLUP:

CLUP02_11113

CHIG:

CH63R_08715

CDET:

87949891(CDEST_13391)

SAPO:

SAPIO_CDS10770

ELA:	UCREL1_5278

PFY:	PFICI_07259

SSL:	SS1G_10541

BFU:	BCIN_04g01580(Bcgcd7)

MBE:

MBM_05060

PSCO:

LY89DRAFT_734842

GLZ:	GLAREA_10174

ANI:	ANIA_01344

AFM:	AFUA_1G09450

ACT:	ACLA_026050

NFI:	NFIA_016160

AOR:	AO090012000928

ANG:	An08g00980

AFV:	AFLA_002650

ALUC:

AKAW2_30884S(GCD7)

ACHE:

ACHE_30938S(GCD7)

APUU:

APUU_50365A(GCD7)

PCS:	N7525_011418

PDP:	PDIP_41110

POU:	POX_d06011

TMF:	EYB26_000994

TRG:	TRUGW13939_03233

CIM:	CIMG_11906(CIMG07125)

CPW:	9695763(GCD7)

URE:	UREG_05776

ABE:

ARB_08003

TVE:

TRV_04600

PBL:	PAAG_00386

PBN:	PADG_02287

AJE:	HCAG_01946

BGH:	BDBG_03869

PNO:	SNOG_04949

PTE:

PTT_18328

PTRR:

6342390(PtrM4_091000)

BZE:	COCCADRAFT_106961

BSC:	COCSADRAFT_99727

BOR:	COCMIDRAFT_100143

AALT:

CC77DRAFT_228431

ADAC:

96084379(ACET3X_004057)

ARAB:

EKO05_0007336

ZTR:	MYCGRDRAFT_77243

PFJ:	MYCFIDRAFT_187374

FFU:	CLAFUR5_14021

CBET:

CB0940_05098

BCOM:

BAUCODRAFT_460357

NPA:	UCRNP2_9012

SPO:	2543035(tif222)

SOM:	SOMG_02037(tif222)

CNE:

CNL06080

CNB:

CNBI0750

CNG:	CNAG_05007

CGI:	CGB_D0660C

CDEU:

CNBG_4673

CDEP:

91086866(L203_102655)

KMG:	30163367(I203_102569)

KNE:	92182367(IAR55_005109)

TMS:	TREMEDRAFT_71172

TASA:

A1Q1_02835

CCAC:

CcaHIS019_0305840(GCD7)

PPL:	POSPLDRAFT_115304

TVS:	TRAVEDRAFT_61514

DSQ:	DICSQDRAFT_98327

PCO:	PHACADRAFT_50940

SHS:	STEHIDRAFT_92333

HIR:	HETIRDRAFT_308679

PSQ:	PUNSTDRAFT_104748

ADL:	AURDEDRAFT_116034

GTR:	GLOTRDRAFT_56481

RSX:	RhiXN_02212

LBC:	LACBIDRAFT_305835

CCI:	CC1G_01152

PCUB:

JR316_0003364

MRR:	Moror_10790

E1B28_009030

SCM:	SCHCO_02605422(SCHCODRAFT_02605422)

SLA:	SERLADRAFT_372886

WSE:	WALSEDRAFT_59344

WIC:	J056_001613

UMA:	UMAG_00997

PFP:	PFL1_01126

SGRA:

MGL:

MRT:

MSYM:

PGR:	PGTG_18270 PGTG_18600

PTRC:

PtA15_12A522

PSTR:

Pst134EA_017661

MLR:	MELLADRAFT_36951

RIE:	OCT59_010954

MBR:	MONBRDRAFT_38213

SRE:	PTSG_12388

DDI:	DDB_G0291271(eIF2b2)

DPP:	DICPUDRAFT_153616

DFA:	DFA_03653(eIF2b2)

EHI:	EHI_019170(93.t00026)

EDI:	EDI_204790

EIV:	EIN_169350

ACAN:

ACA1_192680

PFA:	PF3D7_1250600

PFD:	PFDG_02492

PFH:	PFHG_03643

PREI:

PRSY57_1250000

PGAB:

PGSY75_1250600

PLAG:

39743217(PADL01_1250800)

PYO:	PY17X_1466100

PCB:	PCHAS_1465800

PBE:	PBANKA_1463500

PVV:	PVVCY_1406560

PKN:	PKNH_1470600

PVX:	PVX_101425

PCY:	PCYB_147500

PMAL:

PMUG01_14083800

PBRS:

92373967(MKS88_005880)

PREL:

PRELSG_1465900

PCOT:

PCOAH_00051580

CPV:

cgd5_1600

CHO:	Chro.50223

TGO:	TGME49_313060

TET:	TTHERM_00193960

PTM:	GSPATT00028599001 GSPATT00031243001

PTI:	PHATRDRAFT_21290

FCY:	FRACYDRAFT_141956

TPS:	THAPSDRAFT_6056

PIF:	PITG_10480

PSOJ:

PHYSODRAFT_312818

BLAC:

94347249(CCR75_003484)

SPAR:

SPRG_01783

TBR:	Tb927.8.4390

TBG:	TbgDal_VIII4150

TCR:	506865.40 509569.50

LMA:	LMJF_10_0950

LIF:	LINJ_10_1030

LDO:	LDBPK_101030

LMI:	LMXM_10_0950

LMAT:

92516994(LSCM1_07094)

LPAN:

LPMP_100880

LOI:	92362491(LSCM4_06642)

LEIS:

94182239(GH5_06967)

LENR:

94174542(CUR178_07388)

LEIN:

94191510(JIQ42_07941)

PHET:

94293665(JKF63_07656)

NGR:	NAEGRDRAFT_51423

TVA:	TVAG_2v0504620

GLA:	GL50803_007652

EHX:	EMIHUDRAFT_431349

» show all

Reference

PMID:9472020

Authors

Pavitt GD, Ramaiah KV, Kimball SR, Hinnebusch AG

Title

eIF2 independently binds two distinct eIF2B subcomplexes that catalyze and regulate guanine-nucleotide exchange.

Journal

Genes Dev 12:514-26 (1998)
DOI:10.1101/gad.12.4.514

Sequence

[sce:YLR291C]

Reference

PMID:7596406

Authors

Sherrington R, Rogaev EI, Liang Y, Rogaeva EA, Levesque G, Ikeda M, Chi H, Lin C, Li G, Holman K, Tsuda T, Mar L, Foncin JF, Bruni AC, Montesi MP, Sorbi S, Rainero I, Pinessi L, Nee L, Chumakov I, Pollen D, Brookes A, Sanseau P, Polinsky RJ, Wasco W, Da Silva HA, Haines JL, Perkicak-Vance MA, Tanzi RE, Roses AD, Fraser PE, Rommens JM, St George-Hyslop PH

Title

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease.

Journal

Nature 375:754-60 (1995)
DOI:10.1038/375754a0

Sequence

[hsa:8892]

LinkDB

DBGET integrated database retrieval system