KEGG   ORTHOLOGY: K04011
Entry
K04011                      KO                                     
Symbol
CR1, CD35
Name
complement component (3b/4b) receptor 1
Pathway
map04610  Complement and coagulation cascades
map04613  Neutrophil extracellular trap formation
map04640  Hematopoietic cell lineage
map05134  Legionellosis
map05140  Leishmaniasis
map05144  Malaria
map05152  Tuberculosis
Disease
H00361  Malaria
Brite
KEGG Orthology (KO) [BR:ko00001]
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    K04011  CR1, CD35; complement component (3b/4b) receptor 1
   04610 Complement and coagulation cascades
    K04011  CR1, CD35; complement component (3b/4b) receptor 1
   04613 Neutrophil extracellular trap formation
    K04011  CR1, CD35; complement component (3b/4b) receptor 1
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05134 Legionellosis
    K04011  CR1, CD35; complement component (3b/4b) receptor 1
   05152 Tuberculosis
    K04011  CR1, CD35; complement component (3b/4b) receptor 1
  09174 Infectious disease: parasitic
   05144 Malaria
    K04011  CR1, CD35; complement component (3b/4b) receptor 1
   05140 Leishmaniasis
    K04011  CR1, CD35; complement component (3b/4b) receptor 1
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K04011  CR1, CD35; complement component (3b/4b) receptor 1
  09183 Protein families: signaling and cellular processes
   04090 CD molecules
    K04011  CR1, CD35; complement component (3b/4b) receptor 1
Membrane trafficking [BR:ko04131]
 Endocytosis
  Phagocytosis
   Integrins (complement receptors)
    K04011  CR1, CD35; complement component (3b/4b) receptor 1
CD molecules [BR:ko04090]
 Proteins
  K04011  CD35, CR1; complement component (3b/4b) receptor 1
Other DBs
GO: 0004877 0001861
Genes
HSA: 1378(CR1) 1379(CR1L)
PTR: 449643(CR1) 450119(CR1L)
PPS: 100982795(CR1) 103783766(CR1L)
GGO: 101139740(CR1) 101152327(CR1L)
PON: 100438675(CR1L) 100443325(CR1)
NLE: 100587880(CR1)
MCC: 718120(CR1)
MCF: 102116805(CR1L) 102117401(CR1)
MTHB: 126949087
MNI: 105484964(CR1)
CSAB: 103230172(CR1L) 103231020(CR1)
CATY: 105577086(CR1) 105577089(CR1L)
PANU: 101016492
TGE: 112631312(CR1)
MLEU: 105536432(CR1)
RRO: 104664179 104664181(CR1L)
PTEH: 111531168(CR1)
CANG: 105508881(CR1)
SBQ: 101048758(CR1) 104651759(CR1L)
CIMI: 108302105(CR1)
LCAT: 123626890(CR1)
PCOQ: 105805845(CR1)
OGA: 100947887(CR1)
MMU: 12946(Cr1l)
MCAL: 110289966(Cr1l)
MPAH: 110321621(Cr1l)
RNO: 54243(Cr1l)
CGE: 100772783(Cr1l)
PROB: 127223973(Cr1l)
PLEU: 114687532 114687533(Cr1l)
NGI: 103727019(Cr1l)
HGL: 106010834
DSP: 122109129
NCAR: 124961795
MMMA: 125618504
OCU: 100144334
OPI: 101527358
TUP: 102486522(CR1) 106736063
GVR: 103596051
VLG: 121492857
AML: 100480199
UMR: 103672539
UAR: 123785798(CR1)
LLV: 125086031
MPUF: 101670537(CR1L)
MLK: 131814397(CR1)
ORO: 101384034(CR1L)
ZCA: 113933203(CR1L)
MLX: 118014262(CR1L)
FCA: 102899461(CR1L)
PCOO: 112857686(CR1)
PBG: 122475746(CR1L)
PVIV: 125155671(CR1L)
LRUF: 124510073
PTG: 102963346(CR1)
PPAD: 109255305(CR1L)
PUC: 125925340
AJU: 106981814
BTA: 100138386(CR1L)
CHX: 102187247
OAS: 105614152
MBEZ: 129551005(CR1L)
SSC: 100623585(CR1)
CFR: 102520980(CR1)
CBAI: 105075451(CR1)
CDK: 105100014(CR1) 116148703(CR1L)
VPC: 102528250(CR1)
BACU: 102998630(CR1)
BMUS: 118884475(CR1)
OOR: 101290167(CR1)
DLE: 111184732(CR1)
PSIU: 116760667
NASI: 112403443(CR1L) 112403485
ECB: 106783153(CR1L)
EPZ: 103541409 103556836(CR1) 103556844(CR1L)
MYB: 102258516(CR1)
MYD: 102768212
MMYO: 118673246(CR1)
MLF: 102418475(CR1) 111827234
PKL: 118721675(CR1)
EFUS: 103297471(CR1)
MNA: 107543130(CR1)
DRO: 112318208(CR1)
AJM: 119056794(CR1L) 119058024(CR1)
PDIC: 114512109(CR1)
PHAS: 123826717(CR1)
PPAM: 129062463(CR1)
HAI: 109377857(CR1)
RFQ: 117015038(CR1)
PALE: 102890927
RAY: 107497854(CR1) 107506394
LAV: 100661341
TMU: 101358574
ETF: 101654788
DNM: 101430310
AFZ: 127562612
OAA: 100078027(CD46)
GGA: 419853(CR1L)
CJO: 107324773
NMEL: 110388368(CR1) 110388376
ACYG: 106041274(CR1)
TGU: 100232607
LSR: 110473053(CR1L)
SCAN: 103823334
PMOA: 120495860(CR1)
OTC: 121347945
PRUF: 121353306(CR1)
FAB: 101813858(CR1)
OMA: 130263545
PHI: 102102097(CR1)
PMAJ: 107214784(CR2)
CCW: 104692504
CBRC: 103620376
ETL: 114063123
ZAB: 102075373(CR1)
FPG: 101918890(CR1)
FCH: 102052627(CR1L)
CLV: 102085822(CR1)
EGZ: 104131252
NNI: 104010344
PLET: 104614136
EHS: 104513022
ACUN: 113488794(CR1)
TALA: 104357956
PADL: 103923604
ACHC: 115334971
HALD: 104314970
HLE: 104839002
CMAC: 104483969
MUI: 104547834
BREG: 104632039
FGA: 104084255
GSTE: 104256771
DPUB: 104297273
PGUU: 104467909
ACAR: 104518232
CPEA: 104392614
CVF: 104289334
RTD: 128900460(CR1)
DNE: 112990190(CR2)
AMJ: 102559090(CR1L) 102559514 102559728(CR1)
CCAY: 125625224
PVT: 110086557 110086565(CR1)
SUND: 121928961(CR2)
PBI: 103054975 103059413(CR2)
PMUR: 107288372
PGUT: 117674726
APRI: 131201734
VKO: 123031486
PMUA: 114599337
PRAF: 128415132(CR1)
ZVI: 118088521(CR1)
HCG: 128323132(CR1)
EMC: 129330399(CR1)
NPR: 108791741
GSH: 117347550
IPU: 108275743
TRU: 105418765
MZE: 112429769
CMK: 103182520
CSCU: 111613790
CANU: 128164476
 » show all
Reference
PMID:2972794
  Authors
Klickstein LB, Bartow TJ, Miletic V, Rabson LD, Smith JA, Fearon DT
  Title
Identification of distinct C3b and C4b recognition sites in the human C3b/C4b receptor (CR1, CD35) by deletion mutagenesis.
  Journal
J Exp Med 168:1699-717 (1988)
DOI:10.1084/jem.168.5.1699
  Sequence
[hsa:1378]
Reference
  Authors
Ogembo JG, Kannan L, Ghiran I, Nicholson-Weller A, Finberg RW, Tsokos GC, Fingeroth JD
  Title
Human complement receptor type 1/CD35 is an Epstein-Barr Virus receptor.
  Journal
Cell Rep 3:371-85 (2013)
DOI:10.1016/j.celrep.2013.01.023
  Sequence
[hsa:1378]
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