KEGG   ORTHOLOGY: K04157Help
Entry
K04157                      KO                                     

Name
HTR2
Definition
5-hydroxytryptamine receptor 2
Pathway
ko04020  Calcium signaling pathway
ko04080  Neuroactive ligand-receptor interaction
ko04540  Gap junction
ko04726  Serotonergic synapse
ko04750  Inflammatory mediator regulation of TRP channels
Disease
H01450  Obsessive-compulsive disorder
H01611  Alcohol dependence
H01646  Major depressive disorder
H01649  Schizophrenia
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    K04157  HTR2; 5-hydroxytryptamine receptor 2
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K04157  HTR2; 5-hydroxytryptamine receptor 2
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    K04157  HTR2; 5-hydroxytryptamine receptor 2
 09150 Organismal Systems
  09156 Nervous system
   04726 Serotonergic synapse
    K04157  HTR2; 5-hydroxytryptamine receptor 2
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    K04157  HTR2; 5-hydroxytryptamine receptor 2
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors
    K04157  HTR2; 5-hydroxytryptamine receptor 2
G protein-coupled receptors [BR:ko04030]
 Rhodopsin family
  Biogenic amine
   Serotonin
    K04157  HTR2; 5-hydroxytryptamine receptor 2
BRITE hierarchy
Other DBs
GO: 0004993
TC: 9.A.14.3.7
Genes
HSA: 3356(HTR2A) 3357(HTR2B) 3358(HTR2C)
PTR: 467355(HTR2A) 473740(HTR2C) 737647(HTR2B)
PPS: 100970741(HTR2A) 100985583(HTR2B) 100986689(HTR2C)
GGO: 101128199(HTR2A) 101152068(HTR2C) 101154041(HTR2B)
PON: 100173935(HTR2A) 100440561(HTR2C) 100461323(HTR2B)
NLE: 100585054(HTR2A) 100600461(HTR2C) 105739571(HTR2B)
MCC: 613032(HTR2A) 708141(HTR2C) 711808(HTR2B)
MCF: 101925599(HTR2A) 102120602(HTR2C) 102123932(HTR2B)
CSAB: 103214396(HTR2A) 103218049(HTR2B) 103232513(HTR2C)
RRO: 104657074(HTR2C) 104658160(HTR2A) 104661391(HTR2B) 104675082
CJC: 100387477(HTR2C) 100394497(HTR2B) 100401180(HTR2A)
SBQ: 101034608(HTR2A) 101050137(HTR2C) 104651786(HTR2B)
MMU: 15558(Htr2a) 15559(Htr2b) 15560(Htr2c)
MCAL: 110286873(Htr2c) 110297492(Htr2b) 110309591(Htr2a)
MPAH: 110313621(Htr2c) 110321310(Htr2b) 110325595(Htr2a)
RNO: 25187(Htr2c) 29581(Htr2b) 29595(Htr2a)
MUN: 110542683(Htr2c) 110554410(Htr2a) 110556120(Htr2b)
CGE: 100689471(Htr2a) 100754331(Htr2c) 103161688(Htr2b)
NGI: 103726746(Htr2a) 103738204(Htr2b) 103740878(Htr2c)
HGL: 101699201(Htr2b) 101708395(Htr2a) 101726296(Htr2c)
CCAN: 109674862(Htr2c) 109681473(Htr2b) 109694580(Htr2a)
OCU: 100009461(HTR2A) 100343392(HTR2B) 100343600(HTR2C)
TUP: 102483637(HTR2C) 102487731(HTR2A) 102494933(HTR2B)
CFA: 403881(HTR2B) 403882(HTR2A) 450240(HTR2C)
VVP: 112908428(HTR2C) 112925512(HTR2B) 112933902(HTR2A)
AML: 100464098(HTR2C) 100466077(HTR2B) 100483987(HTR2A)
UMR: 103662679(HTR2B) 103677593(HTR2A) 103679732(HTR2C)
UAH: 113241249(HTR2C) 113250359(HTR2B) 113251337(HTR2A)
ORO: 101363070(HTR2C) 101370581(HTR2B) 101380929(HTR2A)
FCA: 101081108(HTR2A) 101095762(HTR2B) 101099620(HTR2C)
PTG: 102950986(HTR2B) 102963662(HTR2A) 102965088(HTR2C)
PPAD: 109253686(HTR2C) 109264924(HTR2B) 109265941(HTR2A)
AJU: 106972003(HTR2A) 106985374(HTR2C) 106989230(HTR2B)
BTA: 407135(HTR2B) 407230(HTR2A) 538909(HTR2C)
BIU: 109554842(HTR2C) 109566702(HTR2A) 109571939(HTR2B)
BBUB: 102395490(HTR2A) 102396941(HTR2B) 102406013
CHX: 102178674(HTR2B) 102182605(HTR2A) 102188025(HTR2C)
OAS: 101106827(HTR2B) 101108550(HTR2C) 443018(HTR2A)
SSC: 100524920(HTR2C) 396837(HTR2B) 397432(HTR2A)
CFR: 102508630(HTR2A) 102509390 102515846(HTR2B) 102519705(HTR2C)
CDK: 105089744(HTR2A) 105093754(HTR2B) 105102699(HTR2C)
BACU: 103000850(HTR2B) 103009628(HTR2C) 103012145(HTR2A)
LVE: 103073903(HTR2A) 103080324(HTR2B) 103082384(HTR2C)
OOR: 101271859(HTR2A) 101284631(HTR2C) 101286066(HTR2B)
DLE: 111165771(HTR2C) 111171924(HTR2B) 111175327(HTR2A)
PCAD: 102981228(HTR2C) 102983328(HTR2B) 102994764(HTR2A)
ECB: 100009685(HTR2A) 100057052(HTR2B) 100057852(HTR2C)
EPZ: 103542332 103554064(HTR2A) 103557503(HTR2B) 103567740(HTR2C)
EAI: 106825322 106827891(HTR2B) 106829676(HTR2A) 106840829(HTR2C)
MYB: 102247721(HTR2B) 102248200(HTR2A) 102257871(HTR2C)
MYD: 102757521 102761959(HTR2B) 102762407(HTR2A) 102770864(HTR2C)
MNA: 107526926(HTR2A) 107530766(HTR2B) 107537524(HTR2C)
HAI: 109372366(HTR2C) 109374899(HTR2B) 109375158(HTR2A) 109376340
DRO: 112307665(HTR2B) 112308251(HTR2C) 112313639(HTR2A)
PALE: 102886552(HTR2B) 102887090(HTR2C) 102891388(HTR2A)
RAY: 107502272(HTR2A) 107503628(HTR2C) 107504978(HTR2B)
MJV: 108390885(HTR2C) 108400063(HTR2A) 108402174 108409285(HTR2B)
LAV: 100667129(HTR2C) 100667507(HTR2A) 100673510(HTR2B)
MDO: 100011052(HTR2C) 100014874(HTR2B) 100029146(HTR2A)
SHR: 100916548(HTR2A) 100923468(HTR2C) 100925360(HTR2B)
PCW: 110192373(HTR2C) 110198031(HTR2B) 110213438(HTR2A)
OAA: 100077777(HTR2B) 100083607(HTR2A) 100089114(HTR2C)
GGA: 395581(HTR2B) 428070(HTR2A) 428707(HTR2C)
MGP: 100545433(HTR2C) 100547971(HTR2A) 100548582 104912670(HTR2B)
CJO: 107308144(HTR2A) 107312619(HTR2C) 107318169(HTR2B)
NMEL: 110387688(HTR2A) 110398996(HTR2B) 110403168(HTR2C)
APLA: 101792508(HTR2C) 101797990(HTR2B) 101799400(HTR2A)
ACYG: 106035097(HTR2A) 106037442(HTR2C) 106044819(HTR2B)
TGU: 100228803(HTR2B) 100231073(HTR2A) 100231995(HTR2C)
LSR: 110469564(HTR2A) 110478070(HTR2B) 110479894(HTR2C)
SCAN: 103815365(HTR2B) 103816352(HTR2C) 103827411(HTR2A)
GFR: 102031437(HTR2C) 102042340(HTR2B) 102042399(HTR2A)
FAB: 101809829(HTR2A) 101812767(HTR2B) 101814868(HTR2C)
PHI: 102100868(HTR2C) 102101838(HTR2B) 102106216(HTR2A)
PMAJ: 107202093(HTR2A) 107203885(HTR2C) 107208732(HTR2B)
CCAE: 111929360(HTR2C) 111933427(HTR2B) 111933807(HTR2A)
CCW: 104687951(HTR2B) 104689976(HTR2A) 104691663(HTR2C)
ETL: 114057602(HTR2B) 114064170(HTR2A) 114067317(HTR2C)
FPG: 101913447(HTR2A) 101916173(HTR2C) 101919366(HTR2B)
FCH: 102048060(HTR2A) 102048676(HTR2B) 102049402(HTR2C)
CLV: 102085834(HTR2B) 102086029(HTR2A) 102095812(HTR2C)
EGZ: 104123366(HTR2B) 104124263(HTR2C) 104131599(HTR2A)
NNI: 104010904(HTR2A) 104012894(HTR2C) 104015655(HTR2B)
ACUN: 113479963(HTR2C) 113480096(HTR2A) 113483429(HTR2B)
PADL: 103915890(HTR2A) 103916571(HTR2B) 103923352(HTR2C)
AAM: 106489257(HTR2A) 106492948(HTR2C) 106498329(HTR2B)
ASN: 102372520(HTR2A) 102382062(HTR2B) 102382146(HTR2C)
AMJ: 102559315(HTR2B) 102568820(HTR2A) 106737647(HTR2C)
PSS: 102444453(HTR2A) 102462551(HTR2B) 102462937(HTR2C)
CMY: 102929763(HTR2A) 102931448(HTR2B) 102941475(HTR2C)
CPIC: 101932965(HTR2B) 101941354(HTR2A) 101943655 103305687(HTR2C)
ACS: 100564939(htr2c) 100568225(htr2a) 103280552(htr2b)
PVT: 110080131(HTR2C) 110088746(HTR2B) 110090936(HTR2A)
PBI: 103049440(HTR2B) 103052056(HTR2A) 103056807
PMUR: 107284273(HTR2A) 107298396(HTR2B) 107303283(HTR2C)
TSR: 106543701(HTR2A) 106547938 106553044(HTR2B)
PMUA: 114589285 114598199(HTR2B)
GJA: 107112911(HTR2A) 107114689(HTR2C) 107122772(HTR2B)
XLA: 108698473(htr2c.L) 108700167(5HT2C) 108707544(htr2a.L) 108709802(htr2a.S) 108718039 398699(htr2b.L)
XTR: 100492782(htr2a) 100496012(htr2c) 101731179(htr2b)
NPR: 108787214(HTR2C) 108797781(HTR2A) 108804696(HTR2B)
DRE: 100000981(htr2cl1) 559806(htr2ab) 560808(htr2aa) 751784(htr2b)
TRU: 101065375(htr2b) 101072775
LCO: 104923507(htr2b) 104934529 104937824(htr2a)
NCC: 104941298(htr2b) 104956255 104967967(htr2a)
ONL: 100699488(htr2a) 100707925 102082854(htr2b)
OLA: 101162203(htr2b) 101165845 101173822(htr2a)
XMA: 102216937 102225313(htr2a) 102231059(htr2b)
XCO: 114148278(htr2a) 114151104(htr2b) 114158055
PRET: 103463475(htr2b) 103480397 103481442(htr2a)
NFU: 107376997 107389582(htr2a) 107392734(htr2b)
AOCE: 111562806 111577721(htr2b) 111580781(htr2a) 111581919
CSEM: 103386587 103393744(htr2b)
SDU: 111218433(htr2b) 111233466 111237980(htr2a)
SLAL: 111651417(htr2b) 111659539(htr2a) 111667109 111672114
HCQ: 109516666 109517021(htr2a) 109518992(htr2b)
MALB: 109958260(htr2b) 109971365 109972599(htr2a)
CMK: 103177605(htr2a) 103179372(htr2c) 103184487(htr2b)
RTP: 109910745(htr2a) 109927481 109938884(htr2b)
CIN: 104266609
SPU: 105440540
DME: Dmel_CG1056(5-HT2A) Dmel_CG42796(5-HT2B)
DSI: Dsimw501_GD15145(Dsim_GD15145) Dsimw501_GD19740(Dsim_GD19740)
AME: 411323(5-HT2alpha) 552518(5-HT2beta)
ACEP: 105621906
NVI: 107981124
MDL: 103569390
DPX: DAPPUDRAFT_7660(SerR.3)
TUT: 107360876
PTEP: 107450287
CEL: CELE_F59C12.2(ser-1)
CBR: CBG16350(Cbr-ser-1)
TSP: Tsp_02403
PDAM: 113671403
SPIS: 111330902
DGT: 114529873
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Nebigil CG, Choi DS, Dierich A, Hickel P, Le Meur M, Messaddeq N, Launay JM, Maroteaux L
  Title
Serotonin 2B receptor is required for heart development.
  Journal
Proc Natl Acad Sci U S A 97:9508-13 (2000)
DOI:10.1073/pnas.97.17.9508
  Sequence
[mmu:15559]
Reference
PMID:1722404
  Authors
Saltzman AG, Morse B, Whitman MM, Ivanshchenko Y, Jaye M, Felder S
  Title
Cloning of the human serotonin 5-HT2 and 5-HT1C receptor subtypes.
  Journal
Biochem Biophys Res Commun 181:1469-78 (1991)
DOI:10.1016/0006-291X(91)92105-S
  Sequence
[hsa:3356 3358]
Reference
PMID:8078486
  Authors
Kursar JD, Nelson DL, Wainscott DB, Baez M
  Title
Molecular cloning, functional expression, and mRNA tissue distribution of the human 5-hydroxytryptamine2B receptor.
  Journal
Mol Pharmacol 46:227-34 (1994)
  Sequence
[hsa:3357]
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