KEGG   ORTHOLOGY: K04177
Entry
K04177                      KO                                     
Symbol
CCR2, CD192
Name
C-C chemokine receptor type 2
Pathway
map04060  Cytokine-cytokine receptor interaction
map04061  Viral protein interaction with cytokine and cytokine receptor
map04062  Chemokine signaling pathway
Disease
H01360  Allergic rhinitis
H01563  HIV infection
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K04177  CCR2, CD192; C-C chemokine receptor type 2
   04061 Viral protein interaction with cytokine and cytokine receptor
    K04177  CCR2, CD192; C-C chemokine receptor type 2
 09150 Organismal Systems
  09151 Immune system
   04062 Chemokine signaling pathway
    K04177  CCR2, CD192; C-C chemokine receptor type 2
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors
    K04177  CCR2, CD192; C-C chemokine receptor type 2
   04050 Cytokine receptors
    K04177  CCR2, CD192; C-C chemokine receptor type 2
   04090 CD molecules
    K04177  CCR2, CD192; C-C chemokine receptor type 2
G protein-coupled receptors [BR:ko04030]
 Rhodopsin family
  Chemokine
   CC Chemokine
    K04177  CCR2, CD192; C-C chemokine receptor type 2
Cytokine receptors [BR:ko04050]
 Chemokine receptors
  CC Chemokine
   K04177  CCR2, CD192; C-C chemokine receptor type 2
CD molecules [BR:ko04090]
 Proteins
  K04177  CD192, CCR2; chemokine (C-C motif) receptor 2
Other DBs
GO: 0016493
Genes
HSA: 729230(CCR2)
PTR: 740071(CCR2)
PPS: 100971232(CCR2)
GGO: 101152844(CCR2)
PON: 100460754(CCR2)
NLE: 100600152(CCR2)
MCC: 574098(CCR2)
MCF: 102139070(CCR2)
MTHB: 126948589
CSAB: 103227534(CCR2)
CATY: 105573603(CCR2)
PANU: 101005212
TGE: 112618699(CCR2)
RRO: 104671329(CCR2)
RBB: 108517672(CCR2)
TFN: 117080177(CCR2)
PTEH: 111555460(CCR2)
CJC: 100398782(CCR2)
SBQ: 101029020
CSYR: 103273776
MMUR: 105874441(CCR5)
LCAT: 123623099(CCR2)
OGA: 100952845(CCR2)
MMU: 12772(Ccr2)
MCAL: 110302121(Ccr2)
MPAH: 110327781(Ccr2)
RNO: 60463(Ccr2)
MCOC: 116073446(Ccr2)
MUN: 110566893(Ccr2)
CGE: 100762449
MAUA: 121132779(Ccr2)
PLEU: 114685946
MORG: 121464459
MFOT: 126501174
AAMP: 119809805(Ccr2)
NGI: 103728833(Ccr2)
HGL: 101724105(Ccr2)
CPOC: 100718888(Ccr2)
CCAN: 109696494(Ccr2)
DORD: 105996279(Ccr2)
DSP: 122095629
NCAR: 124968379
OCU: 100358097(CCR2)
TUP: 102499629(CCR2)
CFA: 484790(CCR2)
CLUD: 112666829
VVP: 112912504
VLG: 121494286(CCR2)
AML: 100484065(CCR2)
UMR: 103674886(CCR2)
UAH: 113256789(CCR2)
UAR: 123780022(CCR2)
ELK: 111144089
MPUF: 101692076
ORO: 101386073(CCR2)
ZCA: 113918613(CCR2)
MLX: 118004926(CCR2)
NSU: 110574371
FCA: 100049057(CCR2)
PYU: 121011105(CCR2)
PBG: 122487180(CCR2)
LRUF: 124523192
PTG: 102950605(CCR2)
PPAD: 109247712(CCR2)
AJU: 106969042(CCR2)
HHV: 120229385
BTA: 539002(CCR2)
BOM: 102288304(CCR2)
BBUB: 102393452(CCR2)
CHX: 102178953
OAS: 101117706
ODA: 120868160(CCR2)
CCAD: 122425043(CCR2)
SSC: 414372(CCR2)
CFR: 102511746
CBAI: 105078727(CCR2)
CDK: 105103470(CCR2)
VPC: 102534466(CCR2)
BACU: 103003157(CCR2)
LVE: 103089757(CCR2)
OOR: 101274157(CCR2)
DLE: 111174476
PCAD: 102984380
PSIU: 116762255
ECB: 100048936(CCR2)
EPZ: 103555075
EAI: 106838386(CCR2)
MYB: 102252432(CCR2)
MYD: 102763483(CCR2)
MMYO: 118668297(CCR2)
MLF: 102435043(CCR2)
MNA: 107529375
PKL: 118715586
HAI: 109375227(CCR2)
DRO: 112309753
SHON: 118976168(CCR2)
AJM: 119037669(CCR2)
PDIC: 114501622(CCR2)
PHAS: 123830755(CCR2)
MMF: 118633395(CCR2)
RFQ: 117036949
PALE: 102891380
PGIG: 120582273(CCR2)
PVP: 105290283(CCR2)
RAY: 107509098(CCR2)
MJV: 108400628(CCR2)
TOD: 119259162(CCR2)
SARA: 101549920(CCR2)
LAV: 100660192
TMU: 101341117
DNM: 101434065(CCR2)
LCO: 104934762
MZE: 101469701
SDU: 111227909
BPEC: 110162175
PMAX: 117338183
MMER: 123565977
XEN: 124448237
 » show all
Reference
PMID:8146186
  Authors
Charo IF, Myers SJ, Herman A, Franci C, Connolly AJ, Coughlin SR
  Title
Molecular cloning and functional expression of two monocyte chemoattractant protein 1 receptors reveals alternative splicing of the carboxyl-terminal tails.
  Journal
Proc Natl Acad Sci U S A 91:2752-6 (1994)
DOI:10.1073/pnas.91.7.2752
  Sequence
[hsa:729230]
Reference
  Authors
Tan JH, Ludeman JP, Wedderburn J, Canals M, Hall P, Butler SJ, Taleski D, Christopoulos A, Hickey MJ, Payne RJ, Stone MJ
  Title
Tyrosine sulfation of chemokine receptor CCR2 enhances interactions with both monomeric and dimeric forms of the chemokine monocyte chemoattractant protein-1 (MCP-1).
  Journal
J Biol Chem 288:10024-34 (2013)
DOI:10.1074/jbc.M112.447359
  Sequence
[hsa:729230]
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