KEGG   ORTHOLOGY: K04437Help
Entry
K04437                      KO                                     

Name
FLNA
Definition
filamin
Pathway
ko04010  MAPK signaling pathway
ko04510  Focal adhesion
ko05132  Salmonella infection
ko05205  Proteoglycans in cancer
Disease
H00270  Periventricular nodular heterotopia
H00456  Fronto-otopalatodigital syndromes
H00499  Spondylocarpotarsal synostosis syndrome
H00594  Distal myopathy
H00595  Myofibrillar myopathies
H00894  FG syndrome
H01276  Chronic idiopathic intestinal pseudo-obstruction
H01740  Macrothrombocytopenia
H02048  Larsen syndrome
H02064  Atelosteogenesis type I and III
H02067  Boomerang dysplasia
H02227  Frontometaphyseal dysplasia
H02229  Terminal osseous dysplasia
H02230  X-linked cardiac valvular dysplasia
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K04437  FLNA; filamin
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    K04437  FLNA; filamin
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    K04437  FLNA; filamin
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    K04437  FLNA; filamin
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins
    K04437  FLNA; filamin
   04147 Exosome
    K04437  FLNA; filamin
Cytoskeleton proteins [BR:ko04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Cross-linking proteins
     K04437  FLNA; filamin
  Intermediate filaments
   Intermediate filament-binding proteins
    K04437  FLNA; filamin
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   K04437  FLNA; filamin
BRITE hierarchy
Genes
HSA: 2316(FLNA) 2317(FLNB) 2318(FLNC)
PTR: 460476(FLNB) 463711(FLNC) 465940(FLNA)
PPS: 100980320(FLNA) 100991254(FLNC) 100992733(FLNB)
GGO: 101130344(FLNB) 101134853(FLNA) 101142657(FLNC) 101144974
PON: 100436976(FLNB) 100446579(FLNA) 100447210(FLNC)
NLE: 100584689(FLNC) 100585343 100597513(FLNA) 100603369(FLNB)
MCC: 699524(FLNA) 700223(FLNC) 702732(FLNB)
MCF: 102114837(FLNC) 102117123 102134285(FLNB) 102138509(FLNA)
CSAB: 103226867(FLNC) 103227804(FLNB) 103232822(FLNA)
RRO: 104660189(FLNB) 104663540(FLNA) 104674436(FLNC) 104674440
CJC: 100385221(FLNA) 100394911(FLNB) 100397531(FLNC) 103790788
SBQ: 101030782(FLNC) 101033199(FLNB) 101038946(FLNA)
MMU: 192176(Flna) 286940(Flnb) 68794(Flnc)
MCAL: 110287345(Flna) 110297122(Flnc) 110308932(Flnb)
MPAH: 110314123(Flna) 110316290(Flnc) 110325251(Flnb)
RNO: 293860(Flna) 306204(Flnb) 362332(Flnc)
MUN: 110554614(Flnb) 110562530(Flna) 110564415(Flnc)
CGE: 100751994(Flnc) 100760050(Flna) 100769967(Flnb)
HGL: 101702004(Flna) 101714131(Flnb) 101714775(Flnc)
OCU: 100008760(FLNB) 100328754(FLNA) 100328756(RA_M006_JSM7BED4F) 100353671(FLNC)
TUP: 102493536(FLNA) 102497970(FLNB) 102498440(FLNC)
CFA: 481084(FLNA) 482266(FLNC) 484713(FLNB)
VVP: 112909750(FLNB) 112911473(FLNA) 112928910(FLNC)
AML: 100467791 100475857(FLNC) 100481308(FLNB)
UMR: 103674200(FLNB) 103676641(FLNC) 103679686(FLNA)
UAH: 113247826(FLNA) 113257012(FLNB) 113263925(FLNC)
ORO: 101380560(FLNA) 101382948(FLNB) 101383660(FLNC)
FCA: 101081210(FLNC) 101082637(FLNA) 101098612(FLNB)
PTG: 102951673(FLNB) 102958609(FLNC) 102969406(FLNA)
PPAD: 109259850(FLNA) 109268963(FLNC) 109279138(FLNB)
AJU: 106968844(FLNB) 106973900(FLNC) 106989714(FLNA)
BTA: 281165(FLNA) 528415(FLNC) 613533(FLNB)
BOM: 102265714(FLNB) 102281567(FLNA) 102287936(FLNC)
BIU: 109555118(FLNA) 109557606(FLNC) 109576011(FLNB)
BBUB: 102398881(FLNC) 102403050(FLNA) 102411216(FLNB)
CHX: 102170485(FLNC) 102176601(FLNA) 102187630(FLNB)
OAS: 101104655(FLNC) 101120390(FLNA) 101123330(FLNB)
SSC: 100514491(FLNB) 100518997(FLNC) 733585(FLNA)
CDK: 105085371(FLNC) 105089800(FLNB) 105098720(FLNA)
BACU: 103000025(FLNA) 103001285(FLNC) 103018177(FLNB)
LVE: 103070633(FLNA) 103082555(FLNB) 103085481(FLNC)
OOR: 101275748(FLNA) 101277589(FLNC) 101285072(FLNB)
DLE: 111170584(FLNA) 111174250(FLNB) 111178654(FLNC)
PCAD: 102987028(FLNB) 102988864(FLNA) 102994181(FLNC)
ECB: 100057963(FLNB) 100058256(FLNA) 100071760(FLNC)
EAI: 106825616(FLNA) 106839532(FLNC) 106848649(FLNB)
MYB: 102246018(FLNC) 102255293(FLNB) 102257802(FLNA)
MYD: 102756703(FLNC) 102761579(FLNB) 102764268(FLNA)
MNA: 107531471(FLNB) 107537382(FLNC) 107545550(FLNA)
HAI: 109377338(FLNA) 109384635(FLNC) 109388247(FLNB)
DRO: 112296269(FLNA) 112299880(FLNC) 112301177(FLNB)
PALE: 102887099(FLNB) 102889996(FLNA) 102894137(FLNC)
RAY: 107499467(FLNA) 107503384(FLNB) 107512795(FLNC)
MJV: 108387997(FLNA) 108392169(FLNC) 108394917(FLNB)
LAV: 100655159(FLNB) 100666153(FLNC) 100674763(FLNA)
MDO: 100014156(FLNB) 100014995(FLNC) 100617907(FLNA)
SHR: 100923582(FLNB) 100924343(FLNA) 100932639(FLNC)
PCW: 110195967(FLNB) 110200343(FLNA) 110219227(FLNC)
OAA: 100077046(FLNA) 100078338(FLNC) 100084462(FLNB)
GGA: 378913(FLNB) 395260(FLNC) 395261(FLNA)
MGP: 100549125(FLNB)
NMEL: 110391461 110404616(FLNB)
APLA: 101796074(FLNB) 113841470
ACYG: 106037975(FLNB) 106048920(FLNC)
TGU: 100224625(FLNC) 100230709(FLNB) 105759947
LSR: 110471636(FLNB) 110479584(FLNC) 110482785
SCAN: 103817009(FLNB) 103822494(FLNC)
FAB: 101807613(FLNC) 101815478(FLNB)
PHI: 102102293(FLNA) 102109930(FLNC) 102113738(FLNB)
PMAJ: 107198769(FLNC) 107210334(FLNB)
CCW: 104683467(FLNB)
FPG: 101914782(FLNB) 101921248(FLNC)
FCH: 102048385(FLNC) 102055640(FLNB)
EGZ: 104126644(FLNB)
ACUN: 113484731(FLNB)
PADL: 103915476(FLNB)
ASN: 102367807(FLNC) 102368306(FLNB) 102370975(FLNA)
AMJ: 102570042(FLNB) 102572603(FLNC) 102573539(FLNA)
PSS: 102454001(FLNB) 102459888
CMY: 102942474(FLNC) 102947590(FLNB)
CPIC: 101935574(FLNA) 101940457 101948714(FLNC) 101953493(FLNB)
PVT: 110078614(FLNA) 110082409(FLNB) 110089402(FLNC)
PBI: 103050411(FLNC) 103063627(FLNA) 103064197(FLNB)
PMUA: 114587359(FLNA) 114591708(FLNB) 114606020(FLNC)
XTR: 100329116(flnc) 100485165(flnb) 779840(flna)
NPR: 108790450(FLNA) 108791862(FLNB) 108794883(FLNC)
DRE: 100048921(flnca) 100534866(flnb) 562529(flna) 563023(flnb) 570288(flncb)
ELS: 105013504 105013563(flnb) 105021804(flnc)
LCM: 102345455(FLNA) 102352444(FLNC) 102360310(FLNB)
CMK: 103190015(flnc) 103190036(flnb)
CIN: 100186514
SPU: 579510
DME: Dmel_CG30092(jbug) Dmel_CG3937(cher) Dmel_CG5984(CG5984)
DSI: Dsimw501_GD15083(Dsim_GD15083) Dsimw501_GD20251(Dsim_GD20251) Dsimw501_GD25106(Dsim_GD25106)
AAG: 5572167
CLEC: 106661376
CEL: CELE_C23F12.1(fln-2) CELE_Y66H1B.2(fln-1)
AMIL: 114962179
PDAM: 113683703
SPIS: 111330767
DDI: DDB_G0269100(abpC)
DFA: DFA_01474(abpC)
EHI: EHI_104630(3.t00014)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Adams M, Simms RJ, Abdelhamed Z, Dawe HR, Szymanska K, Logan CV, Wheway G, Pitt E, Gull K, Knowles MA, Blair E, Cross SH, Sayer JA, Johnson CA
  Title
A meckelin-filamin A interaction mediates ciliogenesis.
  Journal
Hum Mol Genet 21:1272-86 (2012)
DOI:10.1093/hmg/ddr557
  Sequence
[hsa:2316] [mmu:192176]
LinkDB All DBs

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