KEGG   ORTHOLOGY: K04503
Entry
K04503                      KO                                     

Symbol
CCND1
Name
G1/S-specific cyclin-D1
Pathway
map01522  Endocrine resistance
map04068  FoxO signaling pathway
map04110  Cell cycle
map04115  p53 signaling pathway
map04151  PI3K-Akt signaling pathway
map04152  AMPK signaling pathway
map04218  Cellular senescence
map04310  Wnt signaling pathway
map04340  Hedgehog signaling pathway
map04371  Apelin signaling pathway
map04390  Hippo signaling pathway
map04510  Focal adhesion
map04530  Tight junction
map04630  JAK-STAT signaling pathway
map04917  Prolactin signaling pathway
map04919  Thyroid hormone signaling pathway
map04921  Oxytocin signaling pathway
map04933  AGE-RAGE signaling pathway in diabetic complications
map04934  Cushing syndrome
map04936  Alcoholic liver disease
map05160  Hepatitis C
map05162  Measles
map05163  Human cytomegalovirus infection
map05165  Human papillomavirus infection
map05166  Human T-cell leukemia virus 1 infection
map05167  Kaposi sarcoma-associated herpesvirus infection
map05169  Epstein-Barr virus infection
map05200  Pathways in cancer
map05203  Viral carcinogenesis
map05205  Proteoglycans in cancer
map05206  MicroRNAs in cancer
map05207  Chemical carcinogenesis - receptor activation
map05210  Colorectal cancer
map05212  Pancreatic cancer
map05213  Endometrial cancer
map05214  Glioma
map05215  Prostate cancer
map05216  Thyroid cancer
map05218  Melanoma
map05219  Bladder cancer
map05220  Chronic myeloid leukemia
map05221  Acute myeloid leukemia
map05222  Small cell lung cancer
map05223  Non-small cell lung cancer
map05224  Breast cancer
map05225  Hepatocellular carcinoma
map05226  Gastric cancer
map05416  Viral myocarditis
Disease
H00006  Hairy cell leukemia
H00010  Multiple myeloma
H00016  Oral cancer
H00017  Esophageal cancer
H00031  Breast cancer
H00055  Laryngeal cancer
H00559  von Hippel-Lindau syndrome
H01464  Mantle cell lymphoma
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    K04503  CCND1; G1/S-specific cyclin-D1
   04340 Hedgehog signaling pathway
    K04503  CCND1; G1/S-specific cyclin-D1
   04390 Hippo signaling pathway
    K04503  CCND1; G1/S-specific cyclin-D1
   04371 Apelin signaling pathway
    K04503  CCND1; G1/S-specific cyclin-D1
   04630 JAK-STAT signaling pathway
    K04503  CCND1; G1/S-specific cyclin-D1
   04068 FoxO signaling pathway
    K04503  CCND1; G1/S-specific cyclin-D1
   04151 PI3K-Akt signaling pathway
    K04503  CCND1; G1/S-specific cyclin-D1
   04152 AMPK signaling pathway
    K04503  CCND1; G1/S-specific cyclin-D1
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    K04503  CCND1; G1/S-specific cyclin-D1
   04115 p53 signaling pathway
    K04503  CCND1; G1/S-specific cyclin-D1
   04218 Cellular senescence
    K04503  CCND1; G1/S-specific cyclin-D1
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    K04503  CCND1; G1/S-specific cyclin-D1
   04530 Tight junction
    K04503  CCND1; G1/S-specific cyclin-D1
 09150 Organismal Systems
  09152 Endocrine system
   04917 Prolactin signaling pathway
    K04503  CCND1; G1/S-specific cyclin-D1
   04921 Oxytocin signaling pathway
    K04503  CCND1; G1/S-specific cyclin-D1
   04919 Thyroid hormone signaling pathway
    K04503  CCND1; G1/S-specific cyclin-D1
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K04503  CCND1; G1/S-specific cyclin-D1
   05206 MicroRNAs in cancer
    K04503  CCND1; G1/S-specific cyclin-D1
   05205 Proteoglycans in cancer
    K04503  CCND1; G1/S-specific cyclin-D1
   05207 Chemical carcinogenesis - receptor activation
    K04503  CCND1; G1/S-specific cyclin-D1
   05203 Viral carcinogenesis
    K04503  CCND1; G1/S-specific cyclin-D1
  09162 Cancer: specific types
   05210 Colorectal cancer
    K04503  CCND1; G1/S-specific cyclin-D1
   05212 Pancreatic cancer
    K04503  CCND1; G1/S-specific cyclin-D1
   05225 Hepatocellular carcinoma
    K04503  CCND1; G1/S-specific cyclin-D1
   05226 Gastric cancer
    K04503  CCND1; G1/S-specific cyclin-D1
   05214 Glioma
    K04503  CCND1; G1/S-specific cyclin-D1
   05216 Thyroid cancer
    K04503  CCND1; G1/S-specific cyclin-D1
   05221 Acute myeloid leukemia
    K04503  CCND1; G1/S-specific cyclin-D1
   05220 Chronic myeloid leukemia
    K04503  CCND1; G1/S-specific cyclin-D1
   05218 Melanoma
    K04503  CCND1; G1/S-specific cyclin-D1
   05219 Bladder cancer
    K04503  CCND1; G1/S-specific cyclin-D1
   05215 Prostate cancer
    K04503  CCND1; G1/S-specific cyclin-D1
   05213 Endometrial cancer
    K04503  CCND1; G1/S-specific cyclin-D1
   05224 Breast cancer
    K04503  CCND1; G1/S-specific cyclin-D1
   05222 Small cell lung cancer
    K04503  CCND1; G1/S-specific cyclin-D1
   05223 Non-small cell lung cancer
    K04503  CCND1; G1/S-specific cyclin-D1
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K04503  CCND1; G1/S-specific cyclin-D1
   05160 Hepatitis C
    K04503  CCND1; G1/S-specific cyclin-D1
   05162 Measles
    K04503  CCND1; G1/S-specific cyclin-D1
   05163 Human cytomegalovirus infection
    K04503  CCND1; G1/S-specific cyclin-D1
   05167 Kaposi sarcoma-associated herpesvirus infection
    K04503  CCND1; G1/S-specific cyclin-D1
   05169 Epstein-Barr virus infection
    K04503  CCND1; G1/S-specific cyclin-D1
   05165 Human papillomavirus infection
    K04503  CCND1; G1/S-specific cyclin-D1
  09166 Cardiovascular disease
   05416 Viral myocarditis
    K04503  CCND1; G1/S-specific cyclin-D1
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    K04503  CCND1; G1/S-specific cyclin-D1
   04933 AGE-RAGE signaling pathway in diabetic complications
    K04503  CCND1; G1/S-specific cyclin-D1
   04934 Cushing syndrome
    K04503  CCND1; G1/S-specific cyclin-D1
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    K04503  CCND1; G1/S-specific cyclin-D1
Genes
HSA: 595(CCND1)
PTR: 747442(CCND1)
PPS: 100995605(CCND1)
GGO: 101130447(CCND1)
PON: 100171625(CCND1)
NLE: 100605736(CCND1)
MCC: 574320(CCND1)
MCF: 102135329(CCND1)
CSAB: 103246489(CCND1)
CATY: 105577306(CCND1)
PANU: 101019923(CCND1)
RRO: 104677168(CCND1)
RBB: 108538745(CCND1)
TFN: 117081518(CCND1)
PTEH: 111522272(CCND1)
CJC: 100399312
SBQ: 101047858(CCND1)
MMUR: 105867511(CCND1)
MMU: 12443(Ccnd1)
MCAL: 110298189(Ccnd1)
MPAH: 110322378(Ccnd1)
RNO: 58919(Ccnd1)
MCOC: 116103285(Ccnd1)
MUN: 110546940(Ccnd1)
CGE: 100689063(Ccnd1)
PLEU: 114694498(Ccnd1)
NGI: 103751498(Ccnd1)
HGL: 101712621(Ccnd1)
CCAN: 109696351(Ccnd1)
TUP: 102490651(CCND1)
CFA: 449028(CCND1)
VVP: 112924157(CCND1)
VLG: 121501724(CCND1)
AML: 100469787(CCND1)
UMR: 103671139(CCND1)
UAH: 113243982(CCND1)
ORO: 101371532(CCND1)
ELK: 111149458
MPUF: 101670844(CCND1)
EJU: 114220310(CCND1)
MLX: 118016166(CCND1)
FCA: 100037407(CCND1)
PYU: 121023852(CCND1)
PTG: 102959906(CCND1)
PPAD: 109246902(CCND1)
AJU: 106971167(CCND1)
HHV: 120233874(CCND1)
BTA: 524530(CCND1)
BOM: 102270546(CCND1)
BIU: 109554439(CCND1)
BBUB: 102411133(CCND1)
CHX: 102169650(CCND1)
OAS: 100144763(CCND1)
ODA: 120874144(CCND1)
CCAD: 122430666(CCND1)
SSC: 100738589(CCND1)
CFR: 102518309(CCND1)
CBAI: 105070367(CCND1)
CDK: 105104393(CCND1)
BACU: 103013404(CCND1)
LVE: 103090612(CCND1)
OOR: 101273294(CCND1)
DLE: 111183632(CCND1)
PCAD: 102996914(CCND1)
ECB: 102149114(CCND1)
EAI: 106844248(CCND1)
MYB: 102263484(CCND1)
MYD: 102759793(CCND1)
MMYO: 118665181(CCND1)
MNA: 107537434(CCND1)
HAI: 109389297(CCND1)
DRO: 112317273(CCND1)
SHON: 118998396(CCND1)
AJM: 119041888(CCND1)
MMF: 118628257(CCND1)
PALE: 102885330(CCND1)
PGIG: 120584714(CCND1)
RAY: 107503391(CCND1)
MJV: 108388480(CCND1)
TOD: 119246910 119249876(CCND1)
LAV: 100669703(CCND1)
TMU: 101359745
MDO: 100013257(CCND1)
SHR: 100917462(CCND1)
PCW: 110197171(CCND1)
OAA: 100075081(CCND1)
GGA: 396341(CCND1)
PCOC: 116229085(CCND1)
MGP: 100539759(CCND1)
CJO: 107314428(CCND1)
NMEL: 110400907(CCND1)
APLA: 101800639(CCND1)
ACYG: 106044779(CCND1)
TGU: 100231612(CCND1)
LSR: 110469631(CCND1)
SCAN: 103822217(CCND1)
PMOA: 120509851(CCND1)
GFR: 102042858(CCND1)
FAB: 101807319(CCND1)
PHI: 102099659(CCND1)
PMAJ: 107205992(CCND1)
CCAE: 111930656(CCND1)
CCW: 104697629(CCND1)
ETL: 114067926(CCND1)
FPG: 101914937(CCND1)
FCH: 102053036(CCND1)
CLV: 102086245(CCND1)
EGZ: 104124693(CCND1)
NNI: 104009408(CCND1)
ACUN: 113481227(CCND1)
PADL: 103925769(CCND1)
AAM: 106498229(CCND1)
NPD: 112943487(CCND1)
ASN: 102378816(CCND1)
AMJ: 102563714(CCND1)
CPOO: 109321196(CCND1)
GGN: 109298996(CCND1)
PSS: 102457993(CCND1)
CMY: 102947923(CCND1)
CPIC: 101943958(CCND1)
TST: 117877043(CCND1)
CABI: 116819583(CCND1)
ACS: 100563772(ccnd1)
PVT: 110073542(CCND1)
PBI: 103066913(CCND1)
PMUR: 107285821(CCND1)
TSR: 106546690(CCND1)
PGUT: 117665432(CCND1)
PMUA: 114596879(CCND1)
ZVI: 118085960(CCND1)
GJA: 107121511(CCND1)
XLA: 379161(ccnd1.S) 379937(ccnd1.L) 447541 447748(ccndx.L)
XTR: 448045(ccnd1) 548862(ccndx)
NPR: 108785450(CCND1) 108793412
DRE: 30222(ccnd1)
CCAR: 109093191(ccnd1)
IPU: 108271119(ccnd1)
PHYP: 113528462 113536429(ccnd1)
AMEX: 103031956(ccnd1)
EEE: 113578962(ccnd1) 113588422
TRU: 101061278(ccnd1)
LCO: 104937240(ccnd1) 104939589
NCC: 104950786(ccnd1) 104967413
CGOB: 115004643(ccnd1) 115009127
ELY: 117257798(ccnd1) 117261946
SLUC: 116040204 116041081(ccnd1)
ECRA: 117946450(ccnd1) 117948766
PFLV: 114552928(ccnd1) 114560618
MSAM: 119890260(ccnd1) 119894289
CUD: 121512170(ccnd1) 121514619
MZE: 101467298 101485361(ccnd1)
ONL: 100691051(ccnd1) 100691373
OAU: 116331023 116332748(ccnd1)
OLA: 101169672(ccnd1)
OML: 112141930(ccnd1)
XMA: 102233074(ccnd1)
XCO: 114143123(ccnd1)
XHE: 116719094(ccnd1)
PRET: 103462287(ccnd1)
CVG: 107096221(ccnd1)
CTUL: 119795187(ccnd1)
NFU: 107374449(ccnd1)
KMR: 108237918(ccnd1)
ALIM: 106510985(ccnd1)
AOCE: 111576239(ccnd1)
CSEM: 103379080 103379853(ccnd1)
POV: 109625110(ccnd1) 109642994
SDU: 111221119(ccnd1) 111234824
XGL: 120792411(ccnd1) 120793380(zgc:158868)
BPEC: 110169262(ccnd1) 110174870
MALB: 109967859(ccnd1)
ELS: 105017289(ccnd1) 105018279
SFM: 108940463 108941209(ccnd1)
PKI: 111851863
LOC: 102687804(ccnd1)
ARUT: 117432035(ccnd1) 117435119
LCM: 102361167(CCND1) 102367471
TCA: 660655
HAME: 121864115
EAF: 111700425
FCY: FRACYDRAFT_140762(dsCyc9b)
 » show all
Reference
PMID:1826542
  Authors
Motokura T, Bloom T, Kim HG, Juppner H, Ruderman JV, Kronenberg HM, Arnold A
  Title
A novel cyclin encoded by a bcl1-linked candidate oncogene.
  Journal
Nature 350:512-5 (1991)
DOI:10.1038/350512a0
  Sequence
[hsa:595]
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