KEGG   ORTHOLOGY: K04670
Entry
K04670                      KO                                     

Name
ACVR2A
Definition
activin receptor type-2A [EC:2.7.11.30]
Pathway
ko04060  Cytokine-cytokine receptor interaction
ko04350  TGF-beta signaling pathway
ko04550  Signaling pathways regulating pluripotency of stem cells
ko05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04350 TGF-beta signaling pathway
    K04670  ACVR2A; activin receptor type-2A
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K04670  ACVR2A; activin receptor type-2A
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    K04670  ACVR2A; activin receptor type-2A
 09160 Human Diseases
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    K04670  ACVR2A; activin receptor type-2A
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K04670  ACVR2A; activin receptor type-2A
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.30  receptor protein serine/threonine kinase
     K04670  ACVR2A; activin receptor type-2A
Protein kinases [BR:ko01001]
 Receptor serine/threonine kinases (RSTK): TKL group
  TGFBR2 family [OT]
   K04670  ACVR2A; activin receptor type-2A
Other DBs
GO: 0016362
Genes
HSA: 92(ACVR2A)
PTR: 459646(ACVR2A)
GGO: 101126947(ACVR2A)
PON: 100435220(ACVR2A)
NLE: 100583170(ACVR2A)
MCC: 707017(ACVR2A)
MCF: 102121129(ACVR2A)
CSAB: 103217052(ACVR2A)
RRO: 104655489(ACVR2A)
RBB: 108512386(ACVR2A)
CJC: 100397767(ACVR2A)
SBQ: 101036787(ACVR2A)
MCAL: 110309902(Acvr2a)
MPAH: 110318164(Acvr2a)
RNO: 29263(Acvr2a)
MUN: 110539455(Acvr2a)
NGI: 103727329(Acvr2a)
HGL: 101707586(Acvr2a)
CCAN: 109689204(Acvr2a)
TUP: 102499226(ACVR2A)
CFA: 476140(ACVR2A)
VVP: 112926859(ACVR2A)
UMR: 103667704(ACVR2A)
UAH: 113250906(ACVR2A)
ORO: 101369734(ACVR2A)
ELK: 111145945
FCA: 101097750(ACVR2A)
PTG: 102948807(ACVR2A)
PPAD: 109270733(ACVR2A)
BTA: 281598(ACVR2A)
BOM: 102269861(ACVR2A)
BIU: 109567962(ACVR2A)
BBUB: 102408304(ACVR2A)
CHX: 100860918(ACVR2A)
SSC: 397282(ACVR2A)
LVE: 103079492(ACVR2A)
OOR: 101283151(ACVR2A)
DLE: 111172738(ACVR2A)
PCAD: 102976118(ACVR2A)
ECB: 100049823(ACVR2A)
EPZ: 103549990(ACVR2A)
MYB: 102253638(ACVR2A)
MNA: 107531463(ACVR2A)
HAI: 109388998(ACVR2A)
DRO: 112313101(ACVR2A)
RAY: 107513936(ACVR2A)
MJV: 108391910(ACVR2A)
LAV: 100672302(ACVR2A)
MDO: 100018756(ACVR2A)
SHR: 100918537(ACVR2A)
PCW: 110207162(ACVR2A)
OAA: 100089503(ACVR2A)
GGA: 396324(ACVR2A)
MGP: 100545173(ACVR2A)
CJO: 107317053(ACVR2A)
NMEL: 110399402(ACVR2A)
APLA: 101789784(ACVR2A)
ACYG: 106041002(ACVR2A)
TGU: 100224301(ACVR2A)
LSR: 110476487(ACVR2A)
SCAN: 103814260(ACVR2A)
GFR: 102039219(ACVR2A)
FAB: 101821260(ACVR2A)
PHI: 102113171(ACVR2A)
PMAJ: 107207587(ACVR2A)
CCAE: 111932342(ACVR2A)
CCW: 104694095(ACVR2A)
ETL: 114070947(ACVR2A)
FPG: 101915701(ACVR2A)
FCH: 102053325(ACVR2A)
CLV: 102098638(ACVR2A)
EGZ: 104130385(ACVR2A)
NNI: 104009770(ACVR2A)
ACUN: 113481999(ACVR2A)
PADL: 103912640(ACVR2A)
AAM: 106498516(ACVR2A)
ASN: 102368733(ACVR2A)
AMJ: 102562921(ACVR2A)
PSS: 102454507(ACVR2A)
CMY: 102945188(ACVR2A)
CPIC: 101933615(ACVR2A)
ACS: 100562173(acvr2a)
PVT: 110074952(ACVR2A)
PBI: 103055188(ACVR2A)
PMUR: 107294303(ACVR2A)
TSR: 106545601(ACVR2A)
PMUA: 114604932(ACVR2A)
GJA: 107108802(ACVR2A)
XLA: 399283(acvr2a.L) 495087(acvr2a.S)
XTR: 100216172(acvr2a)
NPR: 108795499(ACVR2A)
DRE: 100331014(acvr2ab) 553359(acvr2aa)
IPU: 108266626 108272703(acvr2a)
EEE: 113581626(acvr2a) 113588617
TRU: 101071858
LCO: 104926240(acvr2a) 104935816
NCC: 104960238(acvr2a)
MZE: 101464704 101481875(acvr2a)
OLA: 100049489(acvr2a)
XMA: 102217256 102227541(acvr2a)
XCO: 114141013(acvr2a) 114147517
PRET: 103457427(acvr2a) 103460036
CVG: 107082824(acvr2a) 107091036
NFU: 107384683(acvr2a)
KMR: 108245115(acvr2a) 108250825
ALIM: 106535166(acvr2a)
CSEM: 103389624(acvr2a)
POV: 109639027(acvr2a) 109642017
SDU: 111230419 111233326(acvr2a)
SLAL: 111656765 111670353(acvr2a)
BPEC: 110153188(acvr2a)
MALB: 109955601(acvr2a) 109970419
SFM: 108924278 108929958(acvr2a)
LCM: 102354804(ACVR2A)
CMK: 103180467(acvr2a)
SPU: 115929923
NVE: 5521759
SPIS: 111320874
DGT: 114519640
HMG: 100204356
 » show all
Reference
PMID:1311955
  Authors
Matzuk MM, Bradley A
  Title
Cloning of the human activin receptor cDNA reveals high evolutionary conservation.
  Journal
Biochim Biophys Acta 1130:105-8 (1992)
DOI:10.1016/0167-4781(92)90472-C
  Sequence
[hsa:92]
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