KEGG   ORTHOLOGY: K04721Help
Entry
K04721                      KO                                     

Name
TNFSF10, TRAIL, CD253
Definition
tumor necrosis factor ligand superfamily member 10
Pathway
ko04060  Cytokine-cytokine receptor interaction
ko04061  Viral protein interaction with cytokine and cytokine receptor
ko04068  FoxO signaling pathway
ko04210  Apoptosis
ko04217  Necroptosis
ko04650  Natural killer cell mediated cytotoxicity
ko05130  Pathogenic Escherichia coli infection
ko05164  Influenza A
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04068 FoxO signaling pathway
    K04721  TNFSF10, TRAIL, CD253; tumor necrosis factor ligand superfamily member 10
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K04721  TNFSF10, TRAIL, CD253; tumor necrosis factor ligand superfamily member 10
   04061 Viral protein interaction with cytokine and cytokine receptor
    K04721  TNFSF10, TRAIL, CD253; tumor necrosis factor ligand superfamily member 10
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    K04721  TNFSF10, TRAIL, CD253; tumor necrosis factor ligand superfamily member 10
   04217 Necroptosis
    K04721  TNFSF10, TRAIL, CD253; tumor necrosis factor ligand superfamily member 10
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    K04721  TNFSF10, TRAIL, CD253; tumor necrosis factor ligand superfamily member 10
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    K04721  TNFSF10, TRAIL, CD253; tumor necrosis factor ligand superfamily member 10
  09172 Infectious disease: viral
   05164 Influenza A
    K04721  TNFSF10, TRAIL, CD253; tumor necrosis factor ligand superfamily member 10
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome
    K04721  TNFSF10, TRAIL, CD253; tumor necrosis factor ligand superfamily member 10
   04052 Cytokines and growth factors
    K04721  TNFSF10, TRAIL, CD253; tumor necrosis factor ligand superfamily member 10
   04090 CD molecules
    K04721  TNFSF10, TRAIL, CD253; tumor necrosis factor ligand superfamily member 10
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of colorectal cancer cells
   K04721  TNFSF10, TRAIL, CD253; tumor necrosis factor ligand superfamily member 10
Cytokines and growth factors [BR:ko04052]
 Cytokines
  Tumor necrosis fators
   K04721  TNFSF10, TRAIL, CD253; tumor necrosis factor ligand superfamily member 10
CD molecules [BR:ko04090]
 Proteins
  K04721  CD253, TNFSF10; tumor necrosis factor (ligand) superfamily, member 10
BRITE hierarchy
Other DBs
GO: 0005164
Genes
HSA: 8743(TNFSF10)
PTR: 460852(TNFSF10)
PPS: 100986991(TNFSF10)
GGO: 101130096(TNFSF10)
PON: 100441526(TNFSF10)
NLE: 100579535(TNFSF10)
MCC: 694451(TNFSF10)
MCF: 101864918(TNFSF10)
CSAB: 103221246(TNFSF10)
RRO: 104657165(TNFSF10)
RBB: 108525949 108540415(TNFSF10)
CJC: 100396000(TNFSF10)
SBQ: 101030281(TNFSF10)
MMU: 22035(Tnfsf10)
MCAL: 110291484(Tnfsf10)
MPAH: 110320972(Tnfsf10)
RNO: 246775(Tnfsf10)
CGE: 100754968(Tnfsf10)
NGI: 103739879(Tnfsf10)
HGL: 101702439(Tnfsf10)
OCU: 100355808(TNFSF10)
TUP: 102501703(TNFSF10)
CFA: 100174780(TNFSF10)
VVP: 112926677(TNFSF10)
AML: 100463573(TNFSF10)
UMR: 103676141(TNFSF10)
UAH: 113255024(TNFSF10)
ORO: 101371152(TNFSF10)
ELK: 111152154
FCA: 100174789(TNFSF10)
PTG: 102963342(TNFSF10)
PPAD: 109275136(TNFSF10)
AJU: 106990055(TNFSF10)
BTA: 507215(TNFSF10)
BOM: 102287110(TNFSF10)
BIU: 109558018(TNFSF10)
BBUB: 102402214(TNFSF10)
CHX: 102173335(TNFSF10)
OAS: 101114153(TNFSF10)
SSC: 406191(TNFSF10)
CFR: 102506160(TNFSF10)
CDK: 105085942(TNFSF10)
BACU: 102997406(TNFSF10)
LVE: 103083521(TNFSF10)
OOR: 101282902(TNFSF10)
DLE: 111173963(TNFSF10)
PCAD: 102992913(TNFSF10)
ECB: 100064377(TNFSF10)
EPZ: 103546356(TNFSF10)
EAI: 106847522(TNFSF10)
MYB: 102262545(TNFSF10)
MYD: 102751425(TNFSF10)
MNA: 107533523(TNFSF10)
HAI: 109371673(TNFSF10)
DRO: 112307528(TNFSF10)
PALE: 102885663(TNFSF10)
RAY: 107516234(TNFSF10)
MJV: 108383372(TNFSF10)
LAV: 100659733(TNFSF10)
TMU: 101359129
MDO: 100010299(TNFSF10)
SHR: 105750042(TNFSF10)
PCW: 110204161(TNFSF10)
OAA: 100074849(TNFSF10)
GGA: 378894(TNFSF10)
MGP: 100550143(TNFSF10)
CJO: 107318308(TNFSF10)
NMEL: 110398962(TNFSF10)
APLA: 101797713(TNFSF10)
ACYG: 106031999(TNFSF10)
TGU: 100227931(TNFSF10)
LSR: 110480362(TNFSF10)
SCAN: 103815595(TNFSF10)
GFR: 102042782(TNFSF10)
FAB: 101806118(TNFSF10)
PHI: 102100672(TNFSF10)
PMAJ: 107208991(TNFSF10)
CCAE: 111933337(TNFSF10)
CCW: 104688035(TNFSF10)
ETL: 114061190(TNFSF10)
FPG: 101922846(TNFSF10)
FCH: 102047699(TNFSF10)
CLV: 102093335(TNFSF10)
EGZ: 104132497(TNFSF10)
NNI: 104022070(TNFSF10)
ACUN: 113483422(TNFSF10)
PADL: 103924981(TNFSF10)
AAM: 106486566(TNFSF10)
ASN: 102371031(TNFSF10)
AMJ: 102576971(TNFSF10)
PSS: 102460636(TNFSF10)
CMY: 102945208(TNFSF10)
CPIC: 101952595(TNFSF10)
ACS: 100566541(tnfsf10)
PVT: 110071293 110079056(TNFSF10)
PBI: 103056379(TNFSF10)
PMUR: 107286546(TNFSF10)
TSR: 106547753(TNFSF10)
PMUA: 114597986(TNFSF10)
XLA: 100316914(tnfsf10.S) 108717006(tnfsf10.L)
XTR: 100493578(tnfsf10)
NPR: 108784823(TNFSF10)
DRE: 436866(tnfsf10)
TRU: 100653422(tnfsf10) 101061420
OLA: 101156131(tnfsf10) 101172365
CVG: 107085098(tnfsf10) 107103203
NFU: 107383107 107392066(tnfsf10)
ALIM: 106522312 106525539(tnfsf10) 106534382
CSEM: 103377512 103378994(tnfsf10)
LCF: 108875098(tnfsf10) 108885067 108902513(tnfsf11)
SLAL: 111651407 111659525 111665906(tnfsf10)
ELS: 105022065
LCM: 102345421(TNFSF10) 102347335
CMK: 103177380 103190454(tnfsf10)
SPU: 100891737
PCAN: 112555287
OBI: 106873185
LAK: 106155782
DGT: 114535243
 » show all
TaxonomyKoalaUniProt
Reference
PMID:8777713
  Authors
Wiley SR, Schooley K, Smolak PJ, Din WS, Huang CP, Nicholl JK, Sutherland GR, Smith TD, Rauch C, Smith CA, et al.
  Title
Identification and characterization of a new member of the TNF family that induces apoptosis.
  Journal
Immunity 3:673-82 (1995)
DOI:10.1016/1074-7613(95)90057-8
  Sequence
[hsa:8743]
Reference
  Authors
McGrath EE, Marriott HM, Lawrie A, Francis SE, Sabroe I, Renshaw SA, Dockrell DH, Whyte MK
  Title
TNF-related apoptosis-inducing ligand (TRAIL) regulates inflammatory neutrophil apoptosis and enhances resolution of inflammation.
  Journal
J Leukoc Biol 90:855-65 (2011)
DOI:10.1189/jlb.0211062
  Sequence
[mmu:22035]
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