KEGG   ORTHOLOGY: K04838
Entry
K04838                      KO                                     

Name
SCN5A, NAV1.5
Definition
voltage-gated sodium channel type V alpha
Pathway
ko04261  Adrenergic signaling in cardiomyocytes
Disease
H00294  Dilated cardiomyopathy
H00720  Long QT syndrome
H00728  Brugada syndrome
H00729  Sick sinus syndrome
H00730  Familial idiopathic ventricular fibrillation
H00731  Atrial fibrillation
H01263  Progressive cardiac conduction defect (PCCD)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09150 Organismal Systems
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    K04838  SCN5A, NAV1.5; voltage-gated sodium channel type V alpha
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels
    K04838  SCN5A, NAV1.5; voltage-gated sodium channel type V alpha
Ion channels [BR:ko04040]
 Voltage-gated cation channels
  Sodium channel, voltage-gated (Nav)
   K04838  SCN5A, NAV1.5; voltage-gated sodium channel type V alpha
Other DBs
GO: 0005248
TC: 1.A.1.10.3
Genes
HSA: 6331(SCN5A)
PTR: 747523(SCN5A)
PPS: 100992941(SCN5A)
GGO: 101149930(SCN5A)
PON: 100459117(SCN5A)
NLE: 100598395(SCN5A)
MCC: 695085(SCN5A)
MCF: 102120184(SCN5A)
CSAB: 103221052(SCN5A)
RRO: 104668732(SCN5A)
RBB: 108513787(SCN5A)
CJC: 100414601(SCN5A)
SBQ: 101049906(SCN5A)
MMU: 20271(Scn5a)
MCAL: 110301251(Scn5a)
MPAH: 110327174(Scn5a)
RNO: 25665(Scn5a)
MUN: 110555054(Scn5a)
CGE: 100751166(Scn5a)
NGI: 103736659(Scn5a)
HGL: 101710111(Scn5a)
CCAN: 109695727(Scn5a)
OCU: 100009516(SCN5A)
TUP: 102496922(SCN5A)
CFA: 403497(SCN5A)
VVP: 112921648(SCN5A)
AML: 100474866(SCN5A)
UMR: 103680654(SCN5A)
UAH: 113253790(SCN5A)
ORO: 101385643(SCN5A)
ELK: 111159034
FCA: 101100994(SCN5A)
PTG: 102950274(SCN5A)
PPAD: 109248762(SCN5A)
AJU: 106966698(SCN5A)
BTA: 282061(SCN5A)
BOM: 102278540(SCN5A)
BIU: 109576489(SCN5A)
BBUB: 102391734(SCN5A)
CHX: 102176565(SCN5A)
OAS: 101111582(SCN5A)
SSC: 100152567(SCN5A)
CFR: 102515216(SCN5A)
CDK: 105084646(SCN5A)
BACU: 103007817(SCN5A)
LVE: 103071162(SCN5A)
OOR: 101283432(SCN5A)
DLE: 111169457(SCN5A)
PCAD: 102989289(SCN5A)
ECB: 100034027(SCN5A)
EPZ: 103561075(SCN5A)
EAI: 106842860(SCN5A)
MYB: 102240070(SCN5A)
MYD: 102759220(SCN5A)
MNA: 107524300(SCN5A)
HAI: 109393494(SCN5A)
DRO: 112309499(SCN5A)
PALE: 102891452(SCN5A)
RAY: 107499591(SCN5A)
MJV: 108386093
TMU: 101343697
MDO: 100653514(SCN5A)
SHR: 100925158
PCW: 110197030
OAA: 100087403
GGA: 395947(SCN5A)
CJO: 107308775
APLA: 101799433
GFR: 102041347 102045246(SCN5A)
FAB: 101819537
PHI: 102107374(SCN5A)
CCW: 104686420(SCN5A)
FPG: 101918751(SCN5A) 101922203
CLV: 102083872(SCN5A)
PADL: 103915628(SCN5A) 103915646
AAM: 106490283(SCN5A)
AMJ: 102565252
PSS: 102452890
CMY: 102931383
ACS: 100565207(scn5a)
GJA: 107111187
XTR: 100485924(scn5a)
NPR: 108784628
DRE: 566868(scn5lab) 795688(scn12aa)
CCAR: 109112823
IPU: 100304599 100305061(Scn5a)
EEE: 113583377
NCC: 104962026
CVG: 107097019
KMR: 108238657
POV: 109640420
OTW: 112227769
CMK: 103188289
 » show all
Reference
  Authors
Zhang H, Zou B, Du F, Xu K, Li M
  Title
Reporting sodium channel activity using calcium flux: pharmacological promiscuity of cardiac Nav1.5.
  Journal
Mol Pharmacol 87:207-17 (2015)
DOI:10.1124/mol.114.094789
  Sequence
[hsa:6331]
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