KEGG   ORTHOLOGY: K04959Help
Entry
K04959                      KO                                     

Name
ITPR2
Definition
inositol 1,4,5-triphosphate receptor type 2
Pathway
ko04020  Calcium signaling pathway
ko04022  cGMP-PKG signaling pathway
ko04070  Phosphatidylinositol signaling system
ko04114  Oocyte meiosis
ko04210  Apoptosis
ko04218  Cellular senescence
ko04270  Vascular smooth muscle contraction
ko04371  Apelin signaling pathway
ko04540  Gap junction
ko04611  Platelet activation
ko04621  NOD-like receptor signaling pathway
ko04625  C-type lectin receptor signaling pathway
ko04720  Long-term potentiation
ko04723  Retrograde endocannabinoid signaling
ko04724  Glutamatergic synapse
ko04725  Cholinergic synapse
ko04726  Serotonergic synapse
ko04728  Dopaminergic synapse
ko04730  Long-term depression
ko04750  Inflammatory mediator regulation of TRP channels
ko04912  GnRH signaling pathway
ko04915  Estrogen signaling pathway
ko04918  Thyroid hormone synthesis
ko04921  Oxytocin signaling pathway
ko04922  Glucagon signaling pathway
ko04924  Renin secretion
ko04925  Aldosterone synthesis and secretion
ko04927  Cortisol synthesis and secretion
ko04928  Parathyroid hormone synthesis, secretion and action
ko04929  GnRH secretion
ko04934  Cushing syndrome
ko04935  Growth hormone synthesis, secretion and action
ko04970  Salivary secretion
ko04971  Gastric acid secretion
ko04972  Pancreatic secretion
ko05010  Alzheimer disease
ko05131  Shigellosis
ko05163  Human cytomegalovirus infection
ko05167  Kaposi sarcoma-associated herpesvirus infection
ko05170  Human immunodeficiency virus 1 infection
ko05205  Proteoglycans in cancer
Disease
H02281  Isolated anhidrosis with normal sweat glands
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04371 Apelin signaling pathway
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   04020 Calcium signaling pathway
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   04070 Phosphatidylinositol signaling system
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   04022 cGMP-PKG signaling pathway
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   04210 Apoptosis
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   04218 Cellular senescence
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
  09144 Cellular community - eukaryotes
   04540 Gap junction
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   04621 NOD-like receptor signaling pathway
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   04625 C-type lectin receptor signaling pathway
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
  09152 Endocrine system
   04922 Glucagon signaling pathway
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   04929 GnRH secretion
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   04912 GnRH signaling pathway
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   04915 Estrogen signaling pathway
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   04921 Oxytocin signaling pathway
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   04935 Growth hormone synthesis, secretion and action
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   04918 Thyroid hormone synthesis
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   04928 Parathyroid hormone synthesis, secretion and action
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   04924 Renin secretion
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   04925 Aldosterone synthesis and secretion
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   04927 Cortisol synthesis and secretion
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
  09154 Digestive system
   04970 Salivary secretion
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   04971 Gastric acid secretion
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   04972 Pancreatic secretion
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
  09156 Nervous system
   04724 Glutamatergic synapse
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   04725 Cholinergic synapse
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   04728 Dopaminergic synapse
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   04726 Serotonergic synapse
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   04720 Long-term potentiation
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   04730 Long-term depression
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   04723 Retrograde endocannabinoid signaling
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
  09171 Infectious disease: bacterial
   05131 Shigellosis
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   05163 Human cytomegalovirus infection
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   05167 Kaposi sarcoma-associated herpesvirus infection
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
Ion channels [BR:ko04040]
 Ligand-gated channels
  IP3 receptor
   K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
BRITE hierarchy
Other DBs
GO: 0005220
TC: 1.A.3.2
Genes
HSA: 3709(ITPR2)
PTR: 473389(ITPR2)
PPS: 100980378(ITPR2)
GGO: 101151502(ITPR2)
PON: 100434318(ITPR2)
NLE: 100599135(ITPR2)
MCC: 708714(ITPR2)
MCF: 102115744(ITPR2)
CSAB: 103218776(ITPR2)
RRO: 104675331(ITPR2)
RBB: 108523739(ITPR2)
SBQ: 101049881(ITPR2)
MMU: 16439(Itpr2)
MCAL: 110295833(Itpr2)
MPAH: 110317251(Itpr2)
RNO: 81678(Itpr2)
MUN: 110558908(Itpr2)
CGE: 100758965(Itpr2)
HGL: 101716022(Itpr2)
OCU: 100356806(ITPR2)
TUP: 102482868(ITPR2)
CFA: 486628(ITPR2)
VVP: 112917203(ITPR2)
AML: 100477888(ITPR2)
UMR: 103665275(ITPR2)
UAH: 113257782(ITPR2)
ORO: 101377380(ITPR2)
FCA: 101101230(ITPR2)
PTG: 102971840(ITPR2)
PPAD: 109268756(ITPR2)
AJU: 106968786(ITPR2)
BTA: 281878(ITPR2)
BOM: 102269013(ITPR2)
BIU: 109558547(ITPR2)
BBUB: 102401062(ITPR2)
CHX: 102170858(ITPR2)
OAS: 101113317
SSC: 100517279(ITPR2)
CFR: 102517295(ITPR2)
CDK: 105102013(ITPR2)
BACU: 103018280(ITPR2)
LVE: 103078697(ITPR2)
OOR: 101281155(ITPR2)
DLE: 111176861(ITPR2)
PCAD: 102984842(ITPR2)
ECB: 100064557(ITPR2)
EPZ: 103546630(ITPR2) 103548182
EAI: 106834887(ITPR2)
MYB: 102256216(ITPR2)
MNA: 107525255(ITPR2)
DRO: 112318382(ITPR2)
PALE: 102896356(ITPR2)
RAY: 107497427(ITPR2)
MJV: 108403293(ITPR2)
LAV: 100667845(ITPR2)
TMU: 101356404
MDO: 100010212(ITPR2)
SHR: 100921270(ITPR2)
PCW: 110193334(ITPR2)
OAA: 103164954(ITPR2)
GGA: 418212(ITPR2)
MGP: 100551445(ITPR2)
CJO: 107316928(ITPR2)
NMEL: 110396437(ITPR2)
APLA: 101791934(ITPR2)
ACYG: 106038242(ITPR2)
TGU: 100230706(ITPR2)
LSR: 110474888(ITPR2)
SCAN: 103819592(ITPR2)
GFR: 102036319(ITPR2)
FAB: 101811180(ITPR2)
PHI: 102112318(ITPR2)
PMAJ: 107204618(ITPR2)
CCAE: 111930014(ITPR2)
CCW: 104696157(ITPR2)
ETL: 114064981(ITPR2)
FPG: 101920370
FCH: 102052635(ITPR2)
CLV: 102096683(ITPR2)
EGZ: 104135140(ITPR2)
NNI: 104012694(ITPR2)
ACUN: 113489114(ITPR2)
PADL: 103924320(ITPR2)
AAM: 106488657
ASN: 102379727
AMJ: 102570264(ITPR2)
PSS: 102453428(ITPR2)
CMY: 102942754(ITPR2)
CPIC: 101931123(ITPR2) 101945828
ACS: 100567982(itpr2)
PVT: 110081241(ITPR2)
PBI: 103058322
PMUR: 107296465(ITPR2)
TSR: 106542057
PMUA: 114604922(ITPR2) 114604923
GJA: 107125949(ITPR2)
XLA: 108710178
XTR: 100124748(itpr2)
NPR: 108786728(ITPR2)
DRE: 562585(itpr2)
SRX: 107730567(itpr2) 107740421
IPU: 108264307(itpr2)
PHYP: 113534384(itpr2)
EEE: 113590571 113592031(itpr2)
TRU: 101063873(itpr2)
LCO: 104924371(itpr2)
MZE: 101466928(itpr2)
ONL: 100690527(itpr2)
OLA: 101155191(itpr2)
XMA: 102220160(itpr2)
XCO: 114157038(itpr2)
PRET: 103466096(itpr2)
CVG: 107104059(itpr2)
NFU: 107388954(itpr2)
KMR: 108239960(itpr2)
ALIM: 106515612(itpr2)
AOCE: 111568340(itpr2)
CSEM: 103380150(itpr2)
POV: 109624047(itpr2)
LCF: 108875355(itpr2)
SDU: 111228375(itpr2)
SLAL: 111655344(itpr2)
HCQ: 109530334(itpr2)
BPEC: 110165611
MALB: 109970756(itpr2)
SASA: 100196824(itpr2)
ELS: 105022141(itpr2)
SFM: 108942564(itpr2)
PKI: 111845672(itpr2)
LCM: 102359880(ITPR2)
CMK: 103188869(itpr2)
RTP: 109918007(itpr2) 109921877
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Iwai M, Tateishi Y, Hattori M, Mizutani A, Nakamura T, Futatsugi A, Inoue T, Furuichi T, Michikawa T, Mikoshiba K
  Title
Molecular cloning of mouse type 2 and type 3 inositol 1,4,5-trisphosphate receptors and identification of a novel type 2 receptor splice variant.
  Journal
J Biol Chem 280:10305-17 (2005)
DOI:10.1074/jbc.M413824200
  Sequence
[mmu:16439]
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