KEGG   ORTHOLOGY: K04981
Entry
K04981                      KO                                     

Name
TRPM6, CHAK2
Definition
transient receptor potential cation channel subfamily M member 6 [EC:2.7.11.1]
Pathway
ko04978  Mineral absorption
Disease
H01210  Hypomagnesemia
Brite
KEGG Orthology (KO) [BR:ko00001]
 09150 Organismal Systems
  09154 Digestive system
   04978 Mineral absorption
    K04981  TRPM6, CHAK2; transient receptor potential cation channel subfamily M member 6
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K04981  TRPM6, CHAK2; transient receptor potential cation channel subfamily M member 6
  09183 Protein families: signaling and cellular processes
   04040 Ion channels
    K04981  TRPM6, CHAK2; transient receptor potential cation channel subfamily M member 6
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     K04981  TRPM6, CHAK2; transient receptor potential cation channel subfamily M member 6
Protein kinases [BR:ko01001]
 Serine/threonine kinases: Other
  Alpha family [OT]
   K04981  TRPM6, CHAK2; transient receptor potential cation channel subfamily M member 6
Ion channels [BR:ko04040]
 Voltage-gated cation channels
  Transient receptor potential channel (TRP)
   K04981  TRPM6, CHAK2; transient receptor potential cation channel subfamily M member 6
Other DBs
GO: 0005262
TC: 1.A.4.5.8
Genes
HSA: 140803(TRPM6)
PTR: 472957(TRPM6)
PPS: 100993141(TRPM6)
GGO: 101141316(TRPM6)
PON: 100449302(TRPM6)
NLE: 100586509(TRPM6)
MCC: 706119(TRPM6)
MCF: 102114781(TRPM6)
CSAB: 103219595(TRPM6)
RRO: 104682191(TRPM6)
RBB: 108542658(TRPM6)
CJC: 100413008(TRPM6)
SBQ: 101049323(TRPM6)
MMU: 225997(Trpm6)
MCAL: 110285256(Trpm6)
MPAH: 110337260(Trpm6)
RNO: 293874(Trpm6)
MUN: 110558143(Trpm6)
CGE: 100771631(Trpm6)
NGI: 103737704(Trpm6)
HGL: 101707911(Trpm6)
OCU: 100345554(TRPM6)
TUP: 102471583(TRPM6)
CFA: 484163(TRPM6)
VVP: 112922062(TRPM6)
AML: 100480512(TRPM6)
UMR: 103663270(TRPM6)
UAH: 113269845(TRPM6)
ELK: 111153633
FCA: 101092301(TRPM6)
PTG: 102950437(TRPM6)
PPAD: 109275383(TRPM6)
AJU: 106982974(TRPM6)
BTA: 527597(TRPM6)
BOM: 102283347(TRPM6)
BIU: 109562963(TRPM6)
BBUB: 102408750(TRPM6)
CHX: 102185359(TRPM6)
OAS: 101114337(TRPM6)
SSC: 100157775(TRPM6)
CFR: 102519057(TRPM6)
CDK: 105106142(TRPM6)
BACU: 103012230(TRPM6)
LVE: 103087343(TRPM6)
DLE: 111174589(TRPM6)
PCAD: 102981038(TRPM6)
ECB: 100054478(TRPM6)
EPZ: 103558420(TRPM6)
EAI: 106836091(TRPM6)
MYB: 102249828(TRPM6)
MYD: 102757488(TRPM6)
MNA: 107544979(TRPM6)
HAI: 109387013(TRPM6)
DRO: 112299668(TRPM6)
PALE: 102891157(TRPM6)
RAY: 107511650(TRPM6)
MJV: 108390801
LAV: 100660086(TRPM6)
MDO: 100020109(TRPM6)
SHR: 100917919(TRPM6)
PCW: 110223196(TRPM6)
OAA: 100075204(TRPM6)
GGA: 100859603(TRPM6)
MGP: 100543277
CJO: 107306212(TRPM6)
NMEL: 110390035(TRPM6)
ACYG: 106044150(TRPM6)
TGU: 100224433(TRPM6)
LSR: 110476496(TRPM6)
SCAN: 103821061(TRPM6)
GFR: 102032555(TRPM6)
FAB: 101813319(TRPM6)
PHI: 102105266(TRPM6)
PMAJ: 107216044(TRPM6)
CCAE: 111941667(TRPM6)
CCW: 104685289(TRPM6)
ETL: 114058706(TRPM6)
FPG: 101916722(TRPM6)
FCH: 102058568(TRPM6)
CLV: 102098942(TRPM6)
EGZ: 104123829(TRPM6)
NNI: 104011393(TRPM6)
ACUN: 113490057(TRPM6)
PADL: 103920433(TRPM6)
ASN: 102383374(TRPM6)
AMJ: 102570433(TRPM6)
PSS: 102451955(TRPM6)
CMY: 102936673(TRPM6)
CPIC: 101943674(TRPM6)
ACS: 100562006(trpm6)
PVT: 110075995(TRPM6)
PBI: 103050645(TRPM6)
PMUR: 107286166(TRPM6)
TSR: 106539701(TRPM6)
PMUA: 114606395(TRPM6)
GJA: 107110738(TRPM6)
XLA: 108714521(trpm6.L)
XTR: 100487366(trpm6)
NPR: 108795305(TRPM6)
DRE: 100149353(trpm6)
IPU: 108255945
PHYP: 113542245
AMEX: 103038531
EEE: 113588635
TRU: 101071857
LCO: 104917868
MZE: 101470275
ONL: 100711567
OLA: 101159200
XMA: 102235160
XCO: 114155109
PRET: 103470583
CVG: 107092757
NFU: 107393684
KMR: 108236508
ALIM: 106520105
AOCE: 111582188
CSEM: 103397405
POV: 109633834
LCF: 108878239
SDU: 111229137
SLAL: 111644988
HCQ: 109511275
BPEC: 110169882
MALB: 109954800
ELS: 105014476
SFM: 108938957
PKI: 111839386
LCM: 102346743(TRPM6)
CMK: 103182374(trpm6)
RTP: 109928628
 » show all
Reference
  Authors
Schlingmann KP, Weber S, Peters M, Niemann Nejsum L, Vitzthum H, Klingel K, Kratz M, Haddad E, Ristoff E, Dinour D, Syrrou M, Nielsen S, Sassen M, Waldegger S, Seyberth HW, Konrad M
  Title
Hypomagnesemia with secondary hypocalcemia is caused by mutations in TRPM6, a new member of the TRPM gene family.
  Journal
Nat Genet 31:166-70 (2002)
DOI:10.1038/ng889
  Sequence
[hsa:140803]
LinkDB

DBGET integrated database retrieval system