KEGG   ORTHOLOGY: K05004Help
Entry
K05004                      KO                                     

Name
KCNJ11, KIR6.2
Definition
potassium inwardly-rectifying channel subfamily J member 11
Pathway
ko04911  Insulin secretion
ko04929  GnRH secretion
ko04930  Type II diabetes mellitus
Disease
H00409  Type 2 diabetes mellitus
H00410  Maturity onset diabetes of the young (MODY)
H00512  Permanent neonatal diabetes mellitus
H00513  Transient neonatal diabetes mellitus
H01267  Familial hyperinsulinemic hypoglycemia
Brite
KEGG Orthology (KO) [BR:ko00001]
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    K05004  KCNJ11, KIR6.2; potassium inwardly-rectifying channel subfamily J member 11
   04929 GnRH secretion
    K05004  KCNJ11, KIR6.2; potassium inwardly-rectifying channel subfamily J member 11
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    K05004  KCNJ11, KIR6.2; potassium inwardly-rectifying channel subfamily J member 11
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels
    K05004  KCNJ11, KIR6.2; potassium inwardly-rectifying channel subfamily J member 11
Ion channels [BR:ko04040]
 Voltage-gated cation channels
  Potassium channel, inwardly-rectifying (Kir)
   K05004  KCNJ11, KIR6.2; potassium inwardly-rectifying channel subfamily J member 11
BRITE hierarchy
Other DBs
GO: 0015272
TC: 1.A.2.1.6 1.A.2.1.7
Genes
HSA: 3767(KCNJ11)
PTR: 466450(KCNJ11)
PPS: 100980303(KCNJ11)
GGO: 101129230(KCNJ11)
PON: 100456411(KCNJ11)
NLE: 100600741(KCNJ11)
MCC: 696722(KCNJ11)
MCF: 102120776(KCNJ11)
CSAB: 103239552(KCNJ11)
RRO: 104667631(KCNJ11)
RBB: 108528224(KCNJ11)
CJC: 100401039(KCNJ11)
SBQ: 101042307(KCNJ11)
MMU: 16514(Kcnj11)
MCAL: 110298992(Kcnj11)
MPAH: 110330563(Kcnj11)
RNO: 83535(Kcnj11)
MUN: 110550463(Kcnj11)
CGE: 100764690(Kcnj11)
NGI: 103734449(Kcnj11)
HGL: 101705172(Kcnj11)
CCAN: 109695036(Kcnj11)
OCU: 100008648(KCNJ11)
TUP: 102491373(KCNJ11)
CFA: 485401(KCNJ11)
VVP: 112927031(KCNJ11)
AML: 100482116(KCNJ11)
UMR: 103679394(KCNJ11)
UAH: 113246617(KCNJ11)
ORO: 101366830(KCNJ11)
FCA: 101097019(KCNJ11)
PTG: 102971792(KCNJ11)
PPAD: 109271200(KCNJ11)
AJU: 106977484(KCNJ11)
BTA: 532060(KCNJ11)
BOM: 102271347(KCNJ11)
BIU: 109569756(KCNJ11)
BBUB: 102404657(KCNJ11)
CHX: 102185938(KCNJ11)
OAS: 101114135(KCNJ11)
SSC: 100158240(KCNJ11)
CFR: 102523652(KCNJ11)
CDK: 105086669(KCNJ11)
BACU: 103000433(KCNJ11)
LVE: 103080959(KCNJ11)
OOR: 101271168(KCNJ11)
DLE: 111165280(KCNJ11)
PCAD: 102975891(KCNJ11)
ECB: 100056520(KCNJ11)
EPZ: 103545814(KCNJ11)
EAI: 106835482(KCNJ11)
MYB: 102243336(KCNJ11)
MYD: 102760388(KCNJ11)
MNA: 107546740(KCNJ11)
HAI: 109388108(KCNJ11)
DRO: 112303443(KCNJ11)
PALE: 102884116(KCNJ11)
RAY: 107508032(KCNJ11)
MJV: 108404863(KCNJ11)
LAV: 100671185(KCNJ11)
TMU: 101358977
MDO: 100020213(KCNJ11)
SHR: 100916146(KCNJ11)
PCW: 110220980(KCNJ11)
OAA: 100078904(KCNJ11)
GGA: 428846(KCNJ11)
MGP: 100548439(KCNJ11)
CJO: 107314656(KCNJ11)
NMEL: 110401615(KCNJ11)
ACYG: 106033944(KCNJ11)
TGU: 101234039(KCNJ11)
LSR: 110468058(KCNJ11)
SCAN: 103827027(KCNJ11)
GFR: 102036380(KCNJ11)
FAB: 101812828(KCNJ11)
PHI: 102105182(KCNJ11)
PMAJ: 107206445(KCNJ11)
CCAE: 111930702(KCNJ11)
CCW: 104687858(KCNJ11)
ETL: 114068368
FPG: 101920113(KCNJ11)
FCH: 102047979(KCNJ11)
CLV: 102097320(KCNJ11)
EGZ: 104123162(KCNJ11)
NNI: 104010917(KCNJ11)
ACUN: 113481076(KCNJ11)
PADL: 103920771(KCNJ11)
AAM: 106497034(KCNJ11)
ASN: 102387184(KCNJ11)
AMJ: 102573244(KCNJ11)
PSS: 102455513(KCNJ11)
CMY: 102944815(KCNJ11)
CPIC: 101950352(KCNJ11)
ACS: 100557606(kcnj11)
PVT: 110083978(KCNJ11)
PBI: 103057667(KCNJ11)
PMUR: 107299623(KCNJ11)
TSR: 106545207(KCNJ11)
PMUA: 114598687(KCNJ11)
GJA: 107120536(KCNJ11)
XTR: 100492679(kcnj11)
DRE: 497647(kcnj11l) 664687(kcnj11)
IPU: 108274973(kcnj11) 108275367
PHYP: 113529697(kcnj11) 113529904
AMEX: 103029391(kcnj11) 103039440
EEE: 113580551(kcnj11) 113584496
LCO: 104936255(kcnj11)
NCC: 104940798(kcnj11) 104953678
MZE: 101469628 101476213(kcnj11)
ONL: 100702542(kcnj11) 100711429
OLA: 101160139(kcnj11) 101160728
XMA: 102223903(kcnj11) 102236473
XCO: 114149749 114156678(kcnj11)
PRET: 103466171(kcnj11) 103466804
CVG: 107089459(kcnj11) 107103515
NFU: 107389035(kcnj11) 107389114
KMR: 108237505(kcnj11) 108251025
ALIM: 106515676(kcnj11) 106531031
POV: 109638970(kcnj11) 109644572
LCF: 108872529 108875228(kcnj11)
SDU: 111228434(kcnj11) 111233716
SLAL: 111661811(kcnj11)
HCQ: 109518256 109530391(kcnj11)
BPEC: 110165921(kcnj11)
MALB: 109967904(kcnj11) 109969132
ELS: 105018669 105030993(kcnj11)
SFM: 108929062 108942174(kcnj11)
PKI: 111846817 111859420(kcnj11)
LCM: 102345462(KCNJ11)
CMK: 103174890(kcnj11)
SMIN: v1.2.021113.t1(symbB.v1.2.021113.t1)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:8607800
  Authors
Tokuyama Y, Fan Z, Furuta H, Makielski JC, Polonsky KS, Bell GI, Yano H
  Title
Rat inwardly rectifying potassium channel Kir6.2: cloning electrophysiological characterization, and decreased expression in pancreatic islets of male Zucker diabetic fatty rats.
  Journal
Biochem Biophys Res Commun 220:532-8 (1996)
DOI:10.1006/bbrc.1996.0439
  Sequence
[rno:83535]
Reference
PMID:7502040
  Authors
Inagaki N, Gonoi T, Clement JP 4th, Namba N, Inazawa J, Gonzalez G, Aguilar-Bryan L, Seino S, Bryan J
  Title
Reconstitution of IKATP: an inward rectifier subunit plus the sulfonylurea receptor.
  Journal
Science 270:1166-70 (1995)
DOI:10.1126/science.270.5239.1166
  Sequence
[hsa:3767]
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