KEGG   ORTHOLOGY: K05036
Entry
K05036                      KO                                     

Symbol
SLC6A3, DAT
Name
solute carrier family 6 (neurotransmitter transporter, dopamine) member 3
Pathway
map04721  Synaptic vesicle cycle
map04728  Dopaminergic synapse
map05012  Parkinson disease
map05022  Pathways of neurodegeneration - multiple diseases
map05030  Cocaine addiction
map05031  Amphetamine addiction
map05034  Alcoholism
Brite
KEGG Orthology (KO) [BR:ko00001]
 09150 Organismal Systems
  09156 Nervous system
   04728 Dopaminergic synapse
    K05036  SLC6A3, DAT; solute carrier family 6 (neurotransmitter transporter, dopamine) member 3
   04721 Synaptic vesicle cycle
    K05036  SLC6A3, DAT; solute carrier family 6 (neurotransmitter transporter, dopamine) member 3
 09160 Human Diseases
  09164 Neurodegenerative disease
   05012 Parkinson disease
    K05036  SLC6A3, DAT; solute carrier family 6 (neurotransmitter transporter, dopamine) member 3
   05022 Pathways of neurodegeneration - multiple diseases
    K05036  SLC6A3, DAT; solute carrier family 6 (neurotransmitter transporter, dopamine) member 3
  09165 Substance dependence
   05030 Cocaine addiction
    K05036  SLC6A3, DAT; solute carrier family 6 (neurotransmitter transporter, dopamine) member 3
   05031 Amphetamine addiction
    K05036  SLC6A3, DAT; solute carrier family 6 (neurotransmitter transporter, dopamine) member 3
   05034 Alcoholism
    K05036  SLC6A3, DAT; solute carrier family 6 (neurotransmitter transporter, dopamine) member 3
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters
    K05036  SLC6A3, DAT; solute carrier family 6 (neurotransmitter transporter, dopamine) member 3
Transporters [BR:ko02000]
 Solute carrier family (SLC)
  SLC6: Sodium- and chloride-dependent neurotransmitter transporter
   K05036  SLC6A3, DAT; solute carrier family 6 (neurotransmitter transporter, dopamine) member 3
Other DBs
GO: 0005330
TC: 2.A.22.1.3
Genes
HSA: 6531(SLC6A3)
PTR: 750842(SLC6A3)
PPS: 100991516(SLC6A3)
PON: 100435121(SLC6A3)
NLE: 100596846(SLC6A3)
MCC: 574143(SLC6A3)
MCF: 102142756(SLC6A3)
CSAB: 103214932(SLC6A3)
CATY: 105600707(SLC6A3)
PANU: 101022805(SLC6A3)
RRO: 104668699(SLC6A3)
RBB: 108513703(SLC6A3)
TFN: 117064705(SLC6A3)
PTEH: 111528338(SLC6A3)
CJC: 100393968(SLC6A3)
SBQ: 101032424(SLC6A3)
MMUR: 105876449(SLC6A3)
MMU: 13162(Slc6a3)
MCAL: 110307893(Slc6a3)
MPAH: 110328936(Slc6a3)
RNO: 24898(Slc6a3)
MCOC: 116083177(Slc6a3)
MUN: 110545376(Slc6a3)
CGE: 100774258
PLEU: 114696105(Slc6a3)
NGI: 103749676(Slc6a3)
HGL: 101709245(Slc6a3)
CCAN: 109698262(Slc6a3)
OCU: 103347477
TUP: 102500212(SLC6A3)
CFA: 609304(SLC6A3)
VVP: 112935444(SLC6A3)
VLG: 121477472(SLC6A3)
AML: 100478402(SLC6A3)
UMR: 103679238(SLC6A3)
UAH: 113260791(SLC6A3)
ORO: 101362179(SLC6A3)
ELK: 111153448
MPUF: 101689277(SLC6A3)
EJU: 114198569(SLC6A3)
MLX: 118006229(SLC6A3)
FCA: 101101618(SLC6A3)
PBG: 122480191(SLC6A3)
PTG: 102971363(SLC6A3)
PPAD: 109267683(SLC6A3)
AJU: 106985115(SLC6A3)
HHV: 120235641(SLC6A3)
BTA: 788410(SLC6A3)
BOM: 102268138(SLC6A3)
BIU: 109574743(SLC6A3)
BBUB: 102401631(SLC6A3)
CHX: 102187167(SLC6A3)
OAS: 101111908(SLC6A3)
ODA: 120879278(SLC6A3)
CCAD: 122454559(SLC6A3)
SSC: 100521346(SLC6A3)
CFR: 102510470(SLC6A3)
CBAI: 105081248(SLC6A3)
CDK: 105102174(SLC6A3)
BACU: 103002528(SLC6A3)
LVE: 103087626(SLC6A3)
OOR: 101289168(SLC6A3)
DLE: 111178539(SLC6A3)
PCAD: 102981726(SLC6A3)
ECB: 100054747(SLC6A3)
EPZ: 103567498(SLC6A3)
EAI: 106835898(SLC6A3)
MYB: 102244563(SLC6A3)
MYD: 102770667(SLC6A3)
MMYO: 118657033(SLC6A3)
MNA: 107536458(SLC6A3)
HAI: 109371679(SLC6A3)
DRO: 112320941(SLC6A3)
SHON: 118998658(SLC6A3)
AJM: 119043343(SLC6A3)
MMF: 118641782(SLC6A3)
PALE: 102895017(SLC6A3)
PGIG: 120586141(SLC6A3)
RAY: 107499955(SLC6A3)
MJV: 108400617(SLC6A3)
TOD: 119260671(SLC6A3)
LAV: 100675742(SLC6A3)
TMU: 101341243
MDO: 100015498(SLC6A3)
SHR: 100914957(SLC6A3)
PCW: 110201221(SLC6A3)
OAA: 100074809(SLC6A3)
XLA: 108720038(slc6a3.S)
XTR: 100488824(slc6a3)
NPR: 108802238(SLC6A3)
DRE: 80787(slc6a3)
SRX: 107758825
SANH: 107701804(slc6a3)
IPU: 108272311
PHYP: 113533694(slc6a3)
AMEX: 103026128(slc6a3)
EEE: 113592231
TRU: 101072244(slc6a3)
LCO: 104940426(slc6a3)
NCC: 104943319(slc6a3)
CGOB: 115021666(slc6a3)
ELY: 117265547(slc6a3)
PLEP: 121945820(slc6a3)
SLUC: 116049211(slc6a3)
ECRA: 117946100(slc6a3)
PFLV: 114557281(slc6a3)
GAT: 120810599(slc6a3)
MSAM: 119897882(slc6a3)
CUD: 121513842(slc6a3)
MZE: 101475398(slc6a3)
ONL: 100706735(slc6a3)
OAU: 116329393(slc6a3)
OLA: 101158881(slc6a3)
OML: 112144056(slc6a3)
XMA: 102218251(slc6a3)
XCO: 114141853(slc6a3)
XHE: 116717885(slc6a3)
PRET: 103478700(slc6a3)
CVG: 107102765(slc6a3)
CTUL: 119791322(slc6a3)
NFU: 107378744(slc6a3)
KMR: 108232182(slc6a3)
ALIM: 106521609
AOCE: 111566236(slc6a3)
CSEM: 103388332(slc6a3)
POV: 109632076(slc6a3)
LCF: 108889083(slc6a3)
SDU: 111227736(slc6a3)
SLAL: 111673067(slc6a3)
XGL: 120784168(slc6a3)
HCQ: 109521906(slc6a3)
BPEC: 110171536(slc6a3)
MALB: 109958350(slc6a3)
OMY: 110511094(slc6a3)
ELS: 105016608(slc6a3)
SFM: 108940585(slc6a3)
PKI: 111843531(slc6a3)
AANG: 118219797(slc6a3)
LOC: 102685205(slc6a3)
LCM: 102364171(SLC6A3)
CMK: 103184821(slc6a3)
RTP: 109935564
BBEL: 109482976
APLC: 110981970
SKO: 100313588
DME: Dmel_CG8380(DAT)
DER: 6548430
DSE: 6609460
DSI: Dsimw501_GD25533(Dsim_GD25533)
DAN: 6494123
DSR: 110188351
DPE: 6590142
DWI: 6640614
DGR: 6571527
DAZ: 108616389
DNV: 108654559
DHE: 111596626
DVI: 6624853
CCAT: 101456969
MDE: 101897187
LCQ: 111685093
ACOZ: 120953301
AARA: 120895525
AAG: 5572892
AALB: 109429040
CPII: 120422641
AME: 412285(Dat)
ACER: 107994910
BIM: 100607968
BBIF: 117207766
BTER: 100645993
CCAL: 108629049
OBB: 114881613
MGEN: 117228829
NMEA: 116432766
CGIG: 122396552
SOC: 105193284
MPHA: 105832387
AEC: 105143343
ACEP: 105623076
PBAR: 105433448
VEM: 105565420
HST: 105189735
DQU: 106740589
CFO: 105253050
FEX: 115243423
LHU: 105677423
PGC: 109861383
OBO: 105277848
PCF: 106794068
MDL: 103572075
CCIN: 107267933
TCA: 655713
DPA: 109541994
ATD: 109594465
AGB: 108908963
LDC: 111513856
NVL: 108564139
PPYR: 116176837
BMOR: 101744281
BMAN: 114248855
BANY: 112043523
PMAC: 106720628
PPOT: 106109110
PRAP: 110996907
ZCE: 119835249
HAW: 110369757
TNL: 113491764
PXY: 105383693
API: 100162013
DNX: 107171027
AGS: 114120239
RMD: 113554711
BTAB: 109037240
CLEC: 106661545
HHAL: 106678308
NLU: 111053418
ZNE: 110840806
CSEC: 111875251
DMK: 116922827
PVM: 113806330
EAF: 111705348
DSV: 119446770
RMP: 119163942
VDE: 111253292
VJA: 111259064
TUT: 107367028
PTEP: 107446382
SDM: 118190547
CEL: CELE_T23G5.5(dat-1)
CBR: CBG10151(Cbr-dat-1)
BMY: BM_BM5960(Bma-dat-1)
TSP: Tsp_00144
BGT: 106074484
CRG: 105321513
MYI: 110464038
PMAX: 117332583
OBI: 106874339
LAK: 106154282
 » show all
Reference
  Authors
Uhl GR
  Title
Dopamine transporter: basic science and human variation of a key molecule for dopaminergic function, locomotion, and parkinsonism.
  Journal
Mov Disord 18 Suppl 7:S71-80 (2003)
DOI:10.1002/mds.10578
Reference
PMID:1406597
  Authors
Giros B, el Mestikawy S, Godinot N, Zheng K, Han H, Yang-Feng T, Caron MG
  Title
Cloning, pharmacological characterization, and chromosome assignment of the human dopamine transporter.
  Journal
Mol Pharmacol 42:383-90 (1992)
  Sequence
[hsa:6531]
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