KEGG   ORTHOLOGY: K05061
Entry
K05061                      KO                                     

Name
CSF3R, CD114
Definition
granulocyte colony-stimulating factor receptor
Pathway
ko04060  Cytokine-cytokine receptor interaction
ko04151  PI3K-Akt signaling pathway
ko04630  JAK-STAT signaling pathway
ko04640  Hematopoietic cell lineage
ko05200  Pathways in cancer
Disease
H02410  Myelodysplastic/myeloproliferative neoplasms
H02412  Atypical chronic myeloid leukemia
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K05061  CSF3R, CD114; granulocyte colony-stimulating factor receptor
   04151 PI3K-Akt signaling pathway
    K05061  CSF3R, CD114; granulocyte colony-stimulating factor receptor
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05061  CSF3R, CD114; granulocyte colony-stimulating factor receptor
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    K05061  CSF3R, CD114; granulocyte colony-stimulating factor receptor
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K05061  CSF3R, CD114; granulocyte colony-stimulating factor receptor
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors
    K05061  CSF3R, CD114; granulocyte colony-stimulating factor receptor
   04090 CD molecules
    K05061  CSF3R, CD114; granulocyte colony-stimulating factor receptor
Cytokine receptors [BR:ko04050]
 Interleukin receptor families
  Prolactin receptor family
   K05061  CSF3R, CD114; granulocyte colony-stimulating factor receptor
CD molecules [BR:ko04090]
 Proteins
  K05061  CD114, CSF3R; colony stimulating factor 3 receptor (granulocyte)
Genes
HSA: 1441(CSF3R)
PTR: 456756(CSF3R)
PPS: 100974292(CSF3R)
GGO: 101128750(CSF3R)
PON: 100433338(CSF3R)
NLE: 100594510(CSF3R)
MCC: 713485(CSF3R)
MCF: 102132219(CSF3R)
CSAB: 103225104(CSF3R)
RRO: 104660161(CSF3R)
RBB: 108537272(CSF3R)
CJC: 100393434(CSF3R)
SBQ: 101042318(CSF3R)
MMU: 12986(Csf3r)
MCAL: 110293219(Csf3r)
MPAH: 110323626(Csf3r)
RNO: 298518(Csf3r)
MUN: 110540287(Csf3r)
CGE: 100760185(Csf3r)
NGI: 103733325(Csf3r)
HGL: 101723599(Csf3r)
CCAN: 109690426(Csf3r)
OCU: 100342746(CSF3R)
TUP: 102471059(CSF3R)
CFA: 607605(CSF3R)
VVP: 112914671(CSF3R)
AML: 100464681(CSF3R)
UMR: 103666378(CSF3R)
UAH: 113268281(CSF3R)
ORO: 101377969(CSF3R)
ELK: 111143352
FCA: 101089787(CSF3R)
PTG: 102961715(CSF3R)
PPAD: 109255488(CSF3R)
AJU: 106973256(CSF3R)
BOM: 102274942(CSF3R)
BIU: 109556495(CSF3R)
BBUB: 102410273(CSF3R)
CHX: 102175546(CSF3R)
OAS: 101118070(CSF3R)
SSC: 100622336(CSF3R)
CFR: 102505807(CSF3R)
CDK: 105086937(CSF3R)
BACU: 103000462(CSF3R)
LVE: 103075275(CSF3R)
OOR: 101275322(CSF3R)
DLE: 111175589(CSF3R)
PCAD: 102980945(CSF3R)
ECB: 100069253(CSF3R)
EPZ: 103549278(CSF3R)
EAI: 106830549(CSF3R)
MYB: 102241961(CSF3R)
MYD: 102764425(CSF3R)
MNA: 107542574(CSF3R)
HAI: 109390482(CSF3R)
DRO: 112299557(CSF3R)
PALE: 102897878(CSF3R)
RAY: 107512067(CSF3R)
MJV: 108400801(CSF3R)
LAV: 100665706(CSF3R)
TMU: 101343066
MDO: 100031592(CSF3R)
SHR: 100928707(CSF3R)
PCW: 110206350(CSF3R)
OAA: 100080173(CSF3R)
GGA: 419620(CSF3R)
MGP: 100542145(CSF3R)
CJO: 107324075(CSF3R)
NMEL: 110387487(CSF3R)
APLA: 101791747(CSF3R)
ACYG: 106038086(CSF3R)
TGU: 100229496(CSF3R)
LSR: 110484278(CSF3R)
SCAN: 103822640(CSF3R)
GFR: 102033859(CSF3R)
FAB: 101807604(CSF3R)
PHI: 102101360(CSF3R)
PMAJ: 107214013(CSF3R)
CCAE: 111938933(CSF3R)
CCW: 104694794(CSF3R)
ETL: 114058886(CSF3R)
FPG: 106112048(CSF3R)
FCH: 106630793(CSF3R)
CLV: 106145641(CSF3R)
NNI: 104017904
AAM: 106490870(CSF3R)
ASN: 102369421 102370521
AMJ: 102560832(CSF3R)
PSS: 102460143(CSF3R)
CMY: 102931914(CSF3R)
CPIC: 101942477(CSF3R)
ACS: 103281080(csf3r) 103282176 103282641
PVT: 110082761(CSF3R)
PBI: 112542138(CSF3R)
PMUR: 114922295(CSF3R)
TSR: 106543650(CSF3R)
PMUA: 114601738(CSF3R)
GJA: 107110150(CSF3R)
XLA: 108704665 446770(csf3r.L)
XTR: 100498116(csf3r)
NPR: 108804707(CSF3R)
DRE: 100134935(csf3r)
SRX: 107732744 107738609
SANH: 107661013 107679306
SGH: 107557599 107598921
CCAR: 109104913
IPU: 108269562(csf3r)
PHYP: 113533987(csf3r)
AMEX: 103033065(csf3r)
EEE: 113578072(csf3r)
TRU: 101072170(csf3r)
LCO: 104919598(csf3r)
NCC: 104941919
MZE: 101478204(csf3r)
ONL: 100703184(csf3r)
OLA: 101166496(csf3r)
XMA: 102231746(csf3r)
XCO: 114142021(csf3r)
PRET: 103477807(csf3r)
CVG: 107084721
NFU: 107396619
KMR: 108235335(csf3r)
ALIM: 106524680(csf3r)
AOCE: 111572351(csf3r)
CSEM: 103387876(csf3r)
POV: 109633009(csf3r)
LCF: 108899580(csf3r)
SDU: 111235806(csf3r)
SLAL: 111661606(csf3r)
HCQ: 109513114(csf3r)
BPEC: 110174290(csf3r)
MALB: 109954603(csf3r)
SASA: 100137055(csf3r)
OTW: 112231743 112233690 112246633
SALP: 111959064 111964732
ELS: 105028375
SFM: 108927808(csf3r)
PKI: 111848842(csf3r)
LCM: 102353589(CSF3R)
 » show all
Reference
PMID:2147944
  Authors
Larsen A, Davis T, Curtis BM, Gimpel S, Sims JE, Cosman D, Park L, Sorensen E, March CJ, Smith CA
  Title
Expression cloning of a human granulocyte colony-stimulating factor receptor: a structural mosaic of hematopoietin receptor, immunoglobulin, and fibronectin domains.
  Journal
J Exp Med 172:1559-70 (1990)
DOI:10.1084/jem.172.6.1559
  Sequence
[hsa:1441]
Reference
PMID:1717255
  Authors
Fukunaga R, Ishizaka-Ikeda E, Pan CX, Seto Y, Nagata S
  Title
Functional domains of the granulocyte colony-stimulating factor receptor.
  Journal
EMBO J 10:2855-65 (1991)
DOI:10.1002/j.1460-2075.1991.tb07835.x
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